NO20054974D0 - 9-azabicyklo(3.3.1)non-6-en derivater med et heteroatom i 3-posisjonen som renin inhibitorer - Google Patents
9-azabicyklo(3.3.1)non-6-en derivater med et heteroatom i 3-posisjonen som renin inhibitorerInfo
- Publication number
- NO20054974D0 NO20054974D0 NO20054974A NO20054974A NO20054974D0 NO 20054974 D0 NO20054974 D0 NO 20054974D0 NO 20054974 A NO20054974 A NO 20054974A NO 20054974 A NO20054974 A NO 20054974A NO 20054974 D0 NO20054974 D0 NO 20054974D0
- Authority
- NO
- Norway
- Prior art keywords
- azabicyclo
- heteroatom
- derivatives
- renin inhibitors
- renin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP0304492 | 2003-04-30 | ||
PCT/EP2004/004371 WO2004096366A1 (en) | 2003-04-30 | 2004-04-26 | 9-azabicyclo’3.3.1!non-6-ee derivatives with a heteroatom at the 3-position as renin inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20054974D0 true NO20054974D0 (no) | 2005-10-26 |
NO20054974L NO20054974L (no) | 2005-11-28 |
Family
ID=33395690
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20054974A NO20054974L (no) | 2003-04-30 | 2005-10-26 | 9-azabicyklo(3.3.1)non-6-en derivater med et heteroatom i 3-posisjonen som renin inhibitorer |
Country Status (13)
Country | Link |
---|---|
US (1) | US20060258648A1 (no) |
EP (1) | EP1622685A1 (no) |
JP (1) | JP2006524655A (no) |
KR (1) | KR20060008937A (no) |
CN (1) | CN1780663A (no) |
AU (1) | AU2004233575A1 (no) |
BR (1) | BRPI0409884A (no) |
CA (1) | CA2521938A1 (no) |
MX (1) | MXPA05011498A (no) |
NO (1) | NO20054974L (no) |
RU (1) | RU2005137155A (no) |
WO (1) | WO2004096366A1 (no) |
ZA (1) | ZA200509661B (no) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1680427A1 (en) * | 2003-10-23 | 2006-07-19 | Actelion Pharmaceuticals Ltd. | Diazabicyclononene and tetrahydropyridine derivatives as renin inhibitors |
CA2547551A1 (en) * | 2003-12-05 | 2005-06-16 | Actelion Pharmaceuticals Ltd | Diazabicyclononene and tetrahydropyridine derivatives with a new side-chain |
WO2006021403A1 (en) * | 2004-08-25 | 2006-03-02 | Actelion Pharmaceuticals Ltd | Bicyclononene derivatives |
ATE462703T1 (de) | 2004-08-25 | 2010-04-15 | Actelion Pharmaceuticals Ltd | Bicyclononen-derivate als renin-inhibitoren |
WO2006058546A1 (en) * | 2004-12-01 | 2006-06-08 | Actelion Pharmaceuticals Ltd | Novel lactame derivatives as renin inhibitors |
WO2006063610A1 (en) * | 2004-12-17 | 2006-06-22 | Actelion Pharmaceuticals Ltd | Heteroaryl substituted diazabicyclononene derivatives |
GB0428526D0 (en) | 2004-12-30 | 2005-02-09 | Novartis Ag | Organic compounds |
GB0514203D0 (en) | 2005-07-11 | 2005-08-17 | Novartis Ag | Organic compounds |
US8129411B2 (en) | 2005-12-30 | 2012-03-06 | Novartis Ag | Organic compounds |
JP2009526767A (ja) | 2006-02-02 | 2009-07-23 | アクテリオン ファーマシューティカルズ リミテッド | 新規二級アミン |
EP2007725A2 (en) * | 2006-03-16 | 2008-12-31 | Nicox S.A. | Non-peptidic renin inhibitors nitroderivatives |
JP2010527942A (ja) | 2007-05-24 | 2010-08-19 | メルク フロスト カナダ リミテツド | 新規類のレニン阻害剤 |
ES2541107T3 (es) | 2007-06-25 | 2015-07-16 | Novartis Ag | Derivados de N5-(2-etoxietil)-N3-(2-piridinil)-3,5-piperidindicarboxamida para su uso como inhibidores de renina |
CA2696689A1 (en) | 2007-08-20 | 2009-02-26 | Merck Frosst Canada Ltd. | Renin inhibitors |
EP2231605A1 (en) | 2007-12-05 | 2010-09-29 | Basf Se | Pyridylmethyl-sulfonamide compounds |
ES2548134T3 (es) | 2008-05-05 | 2015-10-14 | Actelion Pharmaceuticals Ltd. | Derivados de piperidina 3,4-sustituida como inhibidores de renina |
EP2189462B9 (en) * | 2008-11-25 | 2012-06-13 | Universita' Degli Studi di Firenze | Bicyclic peptidomimetic inhibitors of aspartyl-proteases for the treatment of infectious diseases |
CN102093389B (zh) * | 2009-12-09 | 2014-11-19 | 华东理工大学 | 双联和氧桥杂环新烟碱化合物及其制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3509161A (en) * | 1967-07-10 | 1970-04-28 | Boehringer & Soehne Gmbh | 3-phenyl-granatene-(2)-derivatives |
US5380758A (en) * | 1991-03-29 | 1995-01-10 | Brigham And Women's Hospital | S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof |
US5703073A (en) * | 1995-04-19 | 1997-12-30 | Nitromed, Inc. | Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs |
CZ292327B6 (cs) * | 1995-09-07 | 2003-09-17 | F. Hoffmann-La Roche Ag | Derivát 4-(oxyalkoxyfenyl)-3-oxypiperidinu, způsob jeho přípravy, meziprodukt pro jeho přípravu a farmaceutický prostředek, který ho obsahuje |
EP1501830B1 (en) * | 2002-04-29 | 2011-10-05 | Actelion Pharmaceuticals Ltd. | 7-aryl-3,9-diazabicyclo[3.3.1]non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension, cardiovascular or renal diseases |
WO2004002957A1 (en) * | 2002-06-27 | 2004-01-08 | Actelion Pharmaceuticals Ltd | Novel tetrahydropyridine derivatives as renin inhibitors |
-
2004
- 2004-04-26 JP JP2006505260A patent/JP2006524655A/ja active Pending
- 2004-04-26 MX MXPA05011498A patent/MXPA05011498A/es unknown
- 2004-04-26 KR KR1020057020489A patent/KR20060008937A/ko not_active Application Discontinuation
- 2004-04-26 EP EP04729430A patent/EP1622685A1/en not_active Withdrawn
- 2004-04-26 WO PCT/EP2004/004371 patent/WO2004096366A1/en active Application Filing
- 2004-04-26 US US10/554,702 patent/US20060258648A1/en not_active Abandoned
- 2004-04-26 CN CNA2004800116375A patent/CN1780663A/zh active Pending
- 2004-04-26 AU AU2004233575A patent/AU2004233575A1/en not_active Abandoned
- 2004-04-26 BR BRPI0409884-6A patent/BRPI0409884A/pt not_active Application Discontinuation
- 2004-04-26 CA CA002521938A patent/CA2521938A1/en not_active Abandoned
- 2004-04-26 RU RU2005137155/04A patent/RU2005137155A/ru not_active Application Discontinuation
-
2005
- 2005-10-26 NO NO20054974A patent/NO20054974L/no not_active Application Discontinuation
- 2005-11-29 ZA ZA200509661A patent/ZA200509661B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
BRPI0409884A (pt) | 2006-05-23 |
MXPA05011498A (es) | 2005-12-15 |
ZA200509661B (en) | 2006-11-29 |
CA2521938A1 (en) | 2004-11-11 |
WO2004096366A1 (en) | 2004-11-11 |
RU2005137155A (ru) | 2006-03-27 |
EP1622685A1 (en) | 2006-02-08 |
US20060258648A1 (en) | 2006-11-16 |
NO20054974L (no) | 2005-11-28 |
KR20060008937A (ko) | 2006-01-27 |
AU2004233575A1 (en) | 2004-11-11 |
JP2006524655A (ja) | 2006-11-02 |
CN1780663A (zh) | 2006-05-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20054974D0 (no) | 9-azabicyklo(3.3.1)non-6-en derivater med et heteroatom i 3-posisjonen som renin inhibitorer | |
DK1501826T3 (da) | Substituerede indoler som alpha-1-agonister | |
ATE478870T1 (de) | Spiroindolinpiperidinderivate | |
ATE460418T1 (de) | Heterocyclocarboxamidderivate | |
DE60330372D1 (de) | Indol-3-schwefelderivate | |
DK2248807T3 (da) | N-Phenyl-2-pyrimidinaminderivater | |
PL372123A1 (en) | Thiazole derivatives | |
AU2003260345A1 (en) | 2-phenylpyridin-4-yl derivatives as alk5 inhibitors | |
NO20052993D0 (no) | 4,5-diaryltiazolderivater som CB-1 ligander. | |
NO20053215D0 (no) | Pyrazolderivater med anvendelse som COX-1-inhibitorer. | |
NO20050665L (no) | Pyrrolidonderivater som MAOE inhibitoere | |
DK1492785T3 (da) | 2-hydroxy-3-heteroarylindol-derivater som GSK3-inhibitorer | |
NO20053775D0 (no) | Diazepinoindol derivater som kinaseinhibitorer. | |
NO20030055D0 (no) | Colchinolderivater som angiogenese inhibitorer | |
NO20052887D0 (no) | Pyridazinonderivater som GSK-3Beta inhibitorer. | |
NO20014483L (no) | Aminderivater som proteaseinhibitorer | |
IS7453A (is) | Trópan afleiður sem CCR5 stillar | |
ZA200408423B (en) | Novel tetrahydropyridine derivatives as renin inhibitors. | |
DK1633712T3 (da) | Seks leddede amino-amid derivater som angiogenese inhibitorer | |
AU2003250475A8 (en) | 5,6-fused 3,4-dihydropyrimidine-2-one derivatives as matrix metalloproteinase inhibitors | |
DK1963295T3 (da) | 3,6-dihydro-2-oxo-6H-(1,3,4)thiazinderivater | |
DE60327554D1 (de) | Wasserfreies kristallines azidocytosin-hemisulfat-derivat | |
DK1534707T3 (da) | Substituerede 2,4-dihydropyrrolo[3,4-b]quinolin-9-on-derivater egnede som phosphodiesteraseinhibitorer | |
NO20016201D0 (no) | Tienopyrimidiner som fosfodiesteraseinhibitorer | |
IS8042A (is) | Benz[1,2,5]thíadíazól efnasambönd |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |