NO20054078L - Humane antistoffer spesifikke for Interleukin 15 (IL15). - Google Patents
Humane antistoffer spesifikke for Interleukin 15 (IL15).Info
- Publication number
- NO20054078L NO20054078L NO20054078A NO20054078A NO20054078L NO 20054078 L NO20054078 L NO 20054078L NO 20054078 A NO20054078 A NO 20054078A NO 20054078 A NO20054078 A NO 20054078A NO 20054078 L NO20054078 L NO 20054078L
- Authority
- NO
- Norway
- Prior art keywords
- human
- human antibodies
- antibodies
- interleukin
- antibodies specific
- Prior art date
Links
- 102000003812 Interleukin-15 Human genes 0.000 title 2
- 108090000172 Interleukin-15 Proteins 0.000 title 2
- 108010002352 Interleukin-1 Proteins 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 230000009261 transgenic effect Effects 0.000 abstract 2
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 210000004408 hybridoma Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000005215 recombination Methods 0.000 abstract 1
- 230000006798 recombination Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 238000011830 transgenic mouse model Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
Abstract
Sammendrag Isolerte humane monoklonale antistoffer som binder spesifikt til IL-1 5 (f.eks. human IL-1 5) og beslektede antistoffbaserte sammensetninger og molekyler er beskrevet. De humane antistoffene kan produseres i et transfektom eller i et ikke-humant transgent dyr, f.eks. en transgen mus, som kan produsere flere isotyper av humane monoklonale antistoffer ved å gjennomgå V-D-J rekombinasjon og isotypeskifting. Det er også beskrevet farmasøytiske sammensetninger omfattende de humane antistoffene, ikke-humane transgene dyr og hybridomer som produserer de humane antistoffene og terapeutiske og diagnostiske fremgangsmåter for anvendelse av de humane antistoffene.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/374,932 US7329405B2 (en) | 2001-08-23 | 2003-02-26 | Human antibodies specific for interleukin 15 (IL-15) |
US10/379,741 US7247304B2 (en) | 2001-08-23 | 2003-03-05 | Methods of treating using anti-IL-15 antibodies |
PCT/IB2004/000484 WO2004076620A2 (en) | 2003-02-26 | 2004-02-25 | Human antibodies specific for interleukin 15 (il-15) |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20054078D0 NO20054078D0 (no) | 2005-09-01 |
NO20054078L true NO20054078L (no) | 2005-11-02 |
Family
ID=32930206
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20054078A NO20054078L (no) | 2003-02-26 | 2005-09-01 | Humane antistoffer spesifikke for Interleukin 15 (IL15). |
Country Status (14)
Country | Link |
---|---|
US (3) | US7247304B2 (no) |
EP (1) | EP1597283A2 (no) |
KR (1) | KR20050103306A (no) |
AU (1) | AU2004215120B8 (no) |
BR (1) | BRPI0407833A (no) |
CA (1) | CA2516378A1 (no) |
GB (1) | GB2414732B (no) |
HU (1) | HUP0500951A2 (no) |
MX (1) | MXPA05008678A (no) |
NO (1) | NO20054078L (no) |
NZ (1) | NZ542418A (no) |
PL (1) | PL378276A1 (no) |
TW (1) | TWI350290B (no) |
WO (1) | WO2004076620A2 (no) |
Families Citing this family (111)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7247304B2 (en) * | 2001-08-23 | 2007-07-24 | Genmab A/S | Methods of treating using anti-IL-15 antibodies |
US20050123542A1 (en) * | 2003-11-06 | 2005-06-09 | Genmab A/S | Methods for treating disorders involving monocytes |
CU23472A1 (es) * | 2004-09-17 | 2009-12-17 | Ct Ingenieria Genetica Biotech | Péptido antagonista de la interleucina-15 |
NZ554520A (en) * | 2004-10-22 | 2010-03-26 | Amgen Inc | Methods for refolding of recombinant antibodies |
US20080311078A1 (en) | 2005-06-14 | 2008-12-18 | Gokarn Yatin R | Self-Buffering Protein Formulations |
US20070190057A1 (en) | 2006-01-23 | 2007-08-16 | Jian Wu | Methods for modulating mannose content of recombinant proteins |
AR059065A1 (es) * | 2006-01-23 | 2008-03-12 | Amgen Inc | Metodos para modular el contenido de manosa de las proteinas recombinantes |
MX2010002249A (es) * | 2007-08-31 | 2010-03-17 | Amgen Inc | Formulacion de proteina de estado solido. |
EP2197911A2 (en) * | 2007-09-14 | 2010-06-23 | Amgen Inc. | Homogeneous antibody populations |
US8383114B2 (en) * | 2007-09-27 | 2013-02-26 | Amgen Inc. | Pharmaceutical formulations |
EP3381445B1 (en) | 2007-11-15 | 2023-10-25 | Amgen Inc. | Aqueous formulation of antibody stablised by antioxidants for parenteral administration |
EP2282769A4 (en) * | 2008-04-29 | 2012-04-25 | Abbott Lab | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND ITS USES |
CA2726087A1 (en) | 2008-06-03 | 2009-12-10 | Tariq Ghayur | Dual variable domain immunoglobulins and uses thereof |
US9109026B2 (en) | 2008-06-03 | 2015-08-18 | Abbvie, Inc. | Dual variable domain immunoglobulins and uses thereof |
KR20110031369A (ko) | 2008-07-08 | 2011-03-25 | 아보트 러보러터리즈 | 프로스타글란딘 e2 이원 가변 도메인 면역글로불린 및 이의 용도 |
US8298533B2 (en) | 2008-11-07 | 2012-10-30 | Medimmune Limited | Antibodies to IL-1R1 |
UA109633C2 (uk) | 2008-12-09 | 2015-09-25 | Антитіло людини проти тканинного фактора | |
WO2011050333A1 (en) | 2009-10-23 | 2011-04-28 | Amgen Inc. | Vial adapter and system |
ES2545411T5 (es) | 2010-06-07 | 2024-04-05 | Amgen Inc | Dispositivo de administración de fármaco |
PL2580243T3 (pl) | 2010-06-09 | 2020-05-18 | Genmab A/S | Przeciwciała przeciwko ludzkiemu CD38 |
NZ604718A (en) | 2010-06-15 | 2015-01-30 | Genmab As | Human antibody drug conjugates against tissue factor |
CN103298834A (zh) | 2010-08-03 | 2013-09-11 | Abbvie公司 | 双重可变结构域免疫球蛋白及其用途 |
CA2809433A1 (en) | 2010-08-26 | 2012-03-01 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
MX341790B (es) | 2011-03-31 | 2016-09-02 | Amgen Inc | Adaptador de viales y sistema. |
AU2012245231B2 (en) | 2011-04-20 | 2016-10-13 | Amgen Inc. | Autoinjector apparatus |
EA201990685A1 (ru) | 2011-05-17 | 2019-12-30 | Дзе Рокфеллер Юниверсити | Нейтрализующие вирус иммунодефицита человека антитела и способы их применения |
CN103930142B (zh) | 2011-10-14 | 2016-12-14 | 安姆根有限公司 | 注射器和装配方法 |
EP2797955A2 (en) | 2011-12-30 | 2014-11-05 | AbbVie Inc. | Dual variable domain immunoglobulins against il-13 and/or il-17 |
CN104884472B (zh) | 2012-11-01 | 2021-10-15 | 艾伯维公司 | 抗-vegf/dll4双重可变结构域免疫球蛋白及其用途 |
SI3081249T1 (sl) | 2012-11-21 | 2021-03-31 | Amgen Inc. | Naprava za dajanje zdravila |
WO2014144280A2 (en) | 2013-03-15 | 2014-09-18 | Abbvie Inc. | DUAL SPECIFIC BINDING PROTEINS DIRECTED AGAINST IL-1β AND / OR IL-17 |
CA2904725C (en) | 2013-03-15 | 2022-04-12 | Amgen Inc. | Drug cassette, autoinjector, and autoinjector system |
JP6768501B2 (ja) | 2013-03-15 | 2020-10-14 | アムゲン・インコーポレーテッド | 薬物カセット、自動注入機、および自動注入機システム |
WO2014149357A1 (en) | 2013-03-22 | 2014-09-25 | Amgen Inc. | Injector and method of assembly |
PL3060275T3 (pl) | 2013-10-24 | 2019-12-31 | Amgen Inc. | Wstrzykiwacz i sposób montażu |
EP3060281B1 (en) | 2013-10-24 | 2019-01-30 | Amgen Inc. | Drug delivery system with temperature-sensitive control |
WO2015119906A1 (en) | 2014-02-05 | 2015-08-13 | Amgen Inc. | Drug delivery system with electromagnetic field generator |
AU2015256082C1 (en) | 2014-05-07 | 2020-09-10 | Amgen Inc. | Autoinjector with shock reducing elements |
CN112237662B (zh) | 2014-06-03 | 2022-10-21 | 安姆根有限公司 | 药物递送系统和使用方法 |
EP2963057A1 (en) | 2014-07-02 | 2016-01-06 | Calypso Biotech SA | Antibodies to IL-15 |
AU2015332557B2 (en) | 2014-10-14 | 2020-05-14 | Amgen Inc. | Drug injection device with visual and audio indicators |
WO2016094881A2 (en) | 2014-12-11 | 2016-06-16 | Abbvie Inc. | Lrp-8 binding proteins |
ES2785311T3 (es) | 2014-12-19 | 2020-10-06 | Amgen Inc | Dispositivo de administración de fármacos con botón móvil o campo de interfaz de usuario |
JP6716566B2 (ja) | 2014-12-19 | 2020-07-01 | アムジエン・インコーポレーテツド | 近接センサ付き薬物送達装置 |
CA2976935C (en) | 2015-02-17 | 2020-03-10 | Amgen Inc. | Drug delivery device with vacuum assisted securement and/or feedback |
ES2905870T3 (es) | 2015-02-27 | 2022-04-12 | Amgen Inc | Dispositivo de suministro de fármacos que tiene un mecanismo de protección de aguja con un umbral de resistencia ajustable al movimiento de la protección de aguja |
TW201710286A (zh) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | 抗vegf、pdgf及/或其受體之結合蛋白 |
EP3334747B1 (en) | 2015-08-13 | 2023-09-27 | Amgen Inc. | Charged depth filtration of antigen-binding proteins |
WO2017039786A1 (en) | 2015-09-02 | 2017-03-09 | Amgen Inc. | Syringe assembly adapter for a syringe |
WO2017100501A1 (en) | 2015-12-09 | 2017-06-15 | Amgen Inc. | Auto-injector with signaling cap |
WO2017120178A1 (en) | 2016-01-06 | 2017-07-13 | Amgen Inc. | Auto-injector with signaling electronics |
WO2017120479A1 (en) * | 2016-01-07 | 2017-07-13 | The Schepens Eye Research Institute, Inc. | Therapeutics for ocular immunoinflammatory diseases |
EP3429663B1 (en) | 2016-03-15 | 2020-07-15 | Amgen Inc. | Reducing probability of glass breakage in drug delivery devices |
WO2017189089A1 (en) | 2016-04-29 | 2017-11-02 | Amgen Inc. | Drug delivery device with messaging label |
WO2017192287A1 (en) | 2016-05-02 | 2017-11-09 | Amgen Inc. | Syringe adapter and guide for filling an on-body injector |
MX2018013616A (es) | 2016-05-13 | 2019-02-21 | Amgen Inc | Montaje de cubierta protectora de vial. |
US11238150B2 (en) | 2016-05-16 | 2022-02-01 | Amgen Inc. | Data encryption in medical devices with limited computational capability |
WO2017209899A1 (en) | 2016-06-03 | 2017-12-07 | Amgen Inc. | Impact testing apparatuses and methods for drug delivery devices |
US20180002417A1 (en) | 2016-06-15 | 2018-01-04 | Celimmune Llc | Methods and Compositions for the Treatment of Celiac Disease, Non-Celiac Gluten Sensitivity, and Refractory Celiac Disease |
CN109311972A (zh) * | 2016-06-15 | 2019-02-05 | 美国安进公司 | 用于治疗乳糜泻、非乳糜泻麸质敏感和难治性乳糜泻的方法和组合物 |
WO2018004842A1 (en) | 2016-07-01 | 2018-01-04 | Amgen Inc. | Drug delivery device having minimized risk of component fracture upon impact events |
US20190328965A1 (en) | 2016-08-17 | 2019-10-31 | Amgen Inc. | Drug delivery device with placement detection |
EA201990998A1 (ru) | 2016-10-21 | 2019-11-29 | Фармацевтические составы и способы их получения | |
EP3532127A1 (en) | 2016-10-25 | 2019-09-04 | Amgen Inc. | On-body injector |
IL267113B1 (en) * | 2016-12-21 | 2024-05-01 | Cephalon Llc | Antibodies that bind specifically to human IL-15 and their uses |
AU2018210301A1 (en) | 2017-01-17 | 2019-08-01 | Amgen Inc. | Injection devices and related methods of use and assembly |
MX2019009755A (es) | 2017-02-17 | 2019-10-07 | Amgen Inc | Mecanismo de insercion para dispositivo de suministro de farmacos. |
WO2018151890A1 (en) | 2017-02-17 | 2018-08-23 | Amgen Inc. | Drug delivery device with sterile fluid flowpath and related method of assembly |
EP3592403A1 (en) | 2017-03-06 | 2020-01-15 | Amgen Inc. | Drug delivery device with activation prevention feature |
IL268478B2 (en) | 2017-03-07 | 2023-10-01 | Amgen Inc | Inserting a needle using super pressure |
IL268386B2 (en) | 2017-03-09 | 2023-11-01 | Amgen Inc | Insertion mechanism for a drug delivery device |
EP4241807A3 (en) | 2017-03-28 | 2023-10-11 | Amgen Inc. | Plunger rod and syringe assembly system and method |
AU2018282077B2 (en) | 2017-06-08 | 2023-11-23 | Amgen Inc. | Torque driven drug delivery device |
AU2018280054B2 (en) | 2017-06-08 | 2023-07-13 | Amgen Inc. | Syringe assembly for a drug delivery device and method of assembly |
US11541183B2 (en) | 2017-06-22 | 2023-01-03 | Amgen Inc. | Device activation impact/shock reduction |
JP7475860B2 (ja) | 2017-06-23 | 2024-04-30 | アムジエン・インコーポレーテツド | スイッチアセンブリにより起動されるキャップを含む電子薬物送達デバイス |
ES2972207T3 (es) | 2017-07-14 | 2024-06-11 | Amgen Inc | Sistema de inserción-retracción de agujas con sistema de resorte de torsión doble |
MA49626A (fr) | 2017-07-21 | 2020-05-27 | Amgen Inc | Élément d'étanchéité perméable aux gaz pour récipient à médicament et procédés d'assemblage |
EP3658206A1 (en) | 2017-07-25 | 2020-06-03 | Amgen Inc. | Drug delivery device with container access system and related method of assembly |
EP4085942A1 (en) | 2017-07-25 | 2022-11-09 | Amgen Inc. | Drug delivery device with gear module and related method of assembly |
EP3664863A2 (en) | 2017-08-09 | 2020-06-17 | Amgen Inc. | Hydraulic-pneumatic pressurized chamber drug delivery system |
EP3668567A1 (en) | 2017-08-18 | 2020-06-24 | Amgen Inc. | Wearable injector with sterile adhesive patch |
US11103636B2 (en) | 2017-08-22 | 2021-08-31 | Amgen Inc. | Needle insertion mechanism for drug delivery device |
WO2019070472A1 (en) | 2017-10-04 | 2019-04-11 | Amgen Inc. | FLOW ADAPTER FOR MEDICATION DELIVERY DEVICE |
IL272636B1 (en) | 2017-10-06 | 2024-06-01 | Amgen Inc | Drug delivery device with combination assembly and related assembly method |
WO2019074579A1 (en) | 2017-10-09 | 2019-04-18 | Amgen Inc. | DRUG DELIVERY DEVICE COMPRISING A DRIVE ASSEMBLY AND ASSEMBLY METHOD THEREOF |
EP3703778A1 (en) | 2017-11-03 | 2020-09-09 | Amgen Inc. | System and approaches for sterilizing a drug delivery device |
WO2019089178A1 (en) | 2017-11-06 | 2019-05-09 | Amgen Inc. | Drug delivery device with placement and flow sensing |
WO2019090303A1 (en) | 2017-11-06 | 2019-05-09 | Amgen Inc. | Fill-finish assemblies and related methods |
SG11202002966QA (en) | 2017-11-10 | 2020-05-28 | Amgen Inc | Plungers for drug delivery devices |
IL273638B1 (en) | 2017-11-16 | 2024-06-01 | Amgen Inc | Door lock mechanism for drug delivery device |
SG11202002772VA (en) | 2017-11-16 | 2020-04-29 | Amgen Inc | Autoinjector with stall and end point detection |
US10835685B2 (en) | 2018-05-30 | 2020-11-17 | Amgen Inc. | Thermal spring release mechanism for a drug delivery device |
US11083840B2 (en) | 2018-06-01 | 2021-08-10 | Amgen Inc. | Modular fluid path assemblies for drug delivery devices |
WO2020023220A1 (en) | 2018-07-24 | 2020-01-30 | Amgen Inc. | Hybrid drug delivery devices with tacky skin attachment portion and related method of preparation |
WO2020023336A1 (en) | 2018-07-24 | 2020-01-30 | Amgen Inc. | Hybrid drug delivery devices with grip portion |
US12042645B2 (en) | 2018-07-24 | 2024-07-23 | Amgen Inc. | Delivery devices for administering drugs |
MX2021000749A (es) | 2018-07-24 | 2021-03-29 | Amgen Inc | Dispositivos de suministro para administrar farmacos. |
WO2020028009A1 (en) | 2018-07-31 | 2020-02-06 | Amgen Inc. | Fluid path assembly for a drug delivery device |
US20210346601A1 (en) | 2018-09-24 | 2021-11-11 | Amgen Inc. | Interventional dosing systems and methods |
CA3110371A1 (en) | 2018-09-28 | 2020-04-02 | Amgen Inc. | Muscle wire escapement activation assembly for a drug delivery device |
EP3860685A1 (en) | 2018-10-02 | 2021-08-11 | Amgen Inc. | Injection systems for drug delivery with internal force transmission |
EP3860686A1 (en) | 2018-10-05 | 2021-08-11 | Amgen Inc. | Drug delivery device having dose indicator |
CA3109988A1 (en) | 2018-10-15 | 2020-04-23 | Amgen Inc. | Platform assembly process for drug delivery device |
MA53912A (fr) | 2018-10-15 | 2022-01-19 | Amgen Inc | Dispositif d'administration de médicament comprenant un mécanisme d'amortissement |
TWI831847B (zh) | 2018-11-01 | 2024-02-11 | 美商安進公司 | 部分針頭縮回之藥物遞送裝置及其操作方法 |
CA3113076A1 (en) | 2018-11-01 | 2020-05-07 | Amgen Inc. | Drug delivery devices with partial drug delivery member retraction |
US11213620B2 (en) | 2018-11-01 | 2022-01-04 | Amgen Inc. | Drug delivery devices with partial drug delivery member retraction |
MX2021012557A (es) | 2019-04-24 | 2021-11-12 | Amgen Inc | Conjuntos y metodos de verificacion de esterilizacion de jeringuillas. |
MX2022002149A (es) | 2019-08-23 | 2022-03-17 | Amgen Inc | Dispositivo de suministro de farmacos con componentes de acoplamiento de capuchon de aguja configurable y metodos relacionados. |
US20240208680A1 (en) | 2021-05-21 | 2024-06-27 | Amgen Inc. | Method of optimizing a filling recipe for a drug container |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
US6075181A (en) * | 1990-01-12 | 2000-06-13 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
EP0463151B1 (en) * | 1990-01-12 | 1996-06-12 | Cell Genesys, Inc. | Generation of xenogeneic antibodies |
US6255458B1 (en) | 1990-08-29 | 2001-07-03 | Genpharm International | High affinity human antibodies and human antibodies against digoxin |
US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5574138A (en) | 1993-03-08 | 1996-11-12 | Immunex Corporation | Epithelium-derived T-cell factor |
US5591630A (en) | 1994-05-06 | 1997-01-07 | Immunex Corporation | Monoclonal antibodies that bind interleukin-15 receptors |
DE69526960T2 (de) * | 1994-11-15 | 2003-01-02 | Telefonaktiebolaget L M Ericsson (Publ), Stockholm | Dynamische kanalzuteilung für sektorisierte funkzugriffeinheiten eines mobilen kommunikationssystemes |
US5795966A (en) | 1995-02-22 | 1998-08-18 | Immunex Corp | Antagonists of interleukin-15 |
DE69622854T2 (de) | 1995-04-02 | 2003-04-10 | Chugai Seiyaku K.K., Tokio/Tokyo | Arzneimittel zur Heilung von Thrombozytopenie |
AU2466895A (en) | 1995-04-28 | 1996-11-18 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
US5660824A (en) | 1995-05-24 | 1997-08-26 | Grabstein; Kenneth H. | Muscle trophic factor |
CA2252557A1 (en) | 1996-04-26 | 1997-11-06 | Beth Israel Deaconess Medical Center, Inc. | Antagonists of interleukin-15 |
DK0932417T3 (da) | 1996-10-17 | 2003-04-14 | Immunomedics Inc | Non-antigent toxinkonjugat og fusionsprotein af internaliserende receptorsystem |
WO1998036768A1 (en) | 1997-02-21 | 1998-08-27 | Vlaams Interuniversitair Instituut Voor Biotechnologie | Use of interleukin-15 |
ATE332077T1 (de) | 1997-02-28 | 2006-07-15 | Kirin Brewery | Transgene mäuse die ein menschliche antikörper exprimieren |
US5798966A (en) * | 1997-03-31 | 1998-08-25 | Intel Corporation | Flash memory VDS compensation techiques to reduce programming variability |
GB9814892D0 (en) | 1998-07-10 | 1998-09-09 | Kennedy Rheumatology Inst | Treatment of celiac disease |
AU6689700A (en) | 1999-07-06 | 2001-01-22 | Silvia Bulfone-Paus | Method of treating psoriasis with il-15 antagonist |
US20020114781A1 (en) | 2000-09-14 | 2002-08-22 | Strom Terry B. | Modulation of IL-2- and IL-15-mediated T cell responses |
US7247304B2 (en) * | 2001-08-23 | 2007-07-24 | Genmab A/S | Methods of treating using anti-IL-15 antibodies |
CA2456648C (en) | 2001-08-23 | 2011-08-16 | Genmab A/S | Human antibodies specific for interleukin 15 (il-15) |
-
2003
- 2003-03-05 US US10/379,741 patent/US7247304B2/en not_active Expired - Lifetime
-
2004
- 2004-02-25 KR KR1020057015776A patent/KR20050103306A/ko not_active Application Discontinuation
- 2004-02-25 CA CA002516378A patent/CA2516378A1/en not_active Abandoned
- 2004-02-25 WO PCT/IB2004/000484 patent/WO2004076620A2/en active Search and Examination
- 2004-02-25 AU AU2004215120A patent/AU2004215120B8/en not_active Ceased
- 2004-02-25 PL PL378276A patent/PL378276A1/pl not_active Application Discontinuation
- 2004-02-25 MX MXPA05008678A patent/MXPA05008678A/es active IP Right Grant
- 2004-02-25 BR BRPI0407833-0A patent/BRPI0407833A/pt not_active IP Right Cessation
- 2004-02-25 EP EP04714383A patent/EP1597283A2/en not_active Withdrawn
- 2004-02-25 NZ NZ542418A patent/NZ542418A/en not_active IP Right Cessation
- 2004-02-25 GB GB0518243A patent/GB2414732B/en not_active Expired - Lifetime
- 2004-02-25 HU HU0500951A patent/HUP0500951A2/hu unknown
- 2004-02-26 TW TW093104986A patent/TWI350290B/zh not_active IP Right Cessation
-
2005
- 2005-09-01 NO NO20054078A patent/NO20054078L/no not_active Application Discontinuation
-
2007
- 2007-07-11 US US11/827,306 patent/US7597892B2/en not_active Expired - Lifetime
- 2007-07-11 US US11/827,195 patent/US7585961B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US20040071702A1 (en) | 2004-04-15 |
PL378276A1 (pl) | 2006-03-20 |
GB0518243D0 (en) | 2005-10-19 |
US7247304B2 (en) | 2007-07-24 |
WO2004076620A9 (en) | 2004-10-21 |
BRPI0407833A (pt) | 2006-02-14 |
US20080166347A1 (en) | 2008-07-10 |
MXPA05008678A (es) | 2005-11-04 |
US20080166802A1 (en) | 2008-07-10 |
NZ542418A (en) | 2008-07-31 |
WO2004076620A2 (en) | 2004-09-10 |
US7597892B2 (en) | 2009-10-06 |
AU2004215120B8 (en) | 2011-08-11 |
AU2004215120B2 (en) | 2011-07-28 |
GB2414732B (en) | 2007-01-03 |
NO20054078D0 (no) | 2005-09-01 |
AU2004215120A1 (en) | 2004-09-10 |
TWI350290B (en) | 2011-10-11 |
EP1597283A2 (en) | 2005-11-23 |
GB2414732A (en) | 2005-12-07 |
HUP0500951A2 (en) | 2007-07-30 |
TW200500378A (en) | 2005-01-01 |
US7585961B2 (en) | 2009-09-08 |
WO2004076620A3 (en) | 2004-12-23 |
CA2516378A1 (en) | 2004-09-10 |
AU2004215120A8 (en) | 2011-08-11 |
KR20050103306A (ko) | 2005-10-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20054078L (no) | Humane antistoffer spesifikke for Interleukin 15 (IL15). | |
NO20040752L (no) | Humane antistoffer spesifikke for interleukin 15 (IL-15) | |
LTPA2021514I1 (no) | ||
NO20052889L (no) | Humane monoklonale antistoffer mot CD25 | |
WO2003064606A3 (en) | Human monoclonal antibodies to prostate specific membrane antigen (psma) | |
ATE527278T1 (de) | Humane monoklonale antikörper gegen interleukin 8 (il-8) | |
ATE531731T1 (de) | Humane monoklonale antikörper gegen den epidermal-growth-factor-rezeptor (egfr) | |
DE60031279D1 (de) | Humane monoklonale antikörper gegen prostata spezifisches membranantigen | |
WO2004043989A3 (en) | Human monoclonal antibodies to heparanase | |
DE60037896D1 (de) | Menschliche antikörper gegen her2/neu | |
MX2009008706A (es) | Anticuerpos humanos contra el virus de la hepatitis c (hcv) y usos de los mismos. | |
RS20050724A (en) | Human antibodies specific for interleukin 15(il-15) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |