NO20053903L - Nukleotidlipidesterderivater. - Google Patents

Nukleotidlipidesterderivater.

Info

Publication number
NO20053903L
NO20053903L NO20053903A NO20053903A NO20053903L NO 20053903 L NO20053903 L NO 20053903L NO 20053903 A NO20053903 A NO 20053903A NO 20053903 A NO20053903 A NO 20053903A NO 20053903 L NO20053903 L NO 20053903L
Authority
NO
Norway
Prior art keywords
nukleotidlipidesterderivater
lipid esters
tumors
treatment
adenine nucleotides
Prior art date
Application number
NO20053903A
Other languages
English (en)
Norwegian (no)
Other versions
NO20053903D0 (no
Inventor
Dieter Herrmann
Brigitte Heckl-Ostreicher
Christoph Mueller
Christian Lutz
Robert Voigt
Original Assignee
Heidelberg Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heidelberg Pharma Gmbh filed Critical Heidelberg Pharma Gmbh
Publication of NO20053903D0 publication Critical patent/NO20053903D0/no
Publication of NO20053903L publication Critical patent/NO20053903L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fats And Perfumes (AREA)
  • Medicines Containing Plant Substances (AREA)
NO20053903A 2003-03-19 2005-08-22 Nukleotidlipidesterderivater. NO20053903L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45600303P 2003-03-19 2003-03-19
EP03006059A EP1460082A1 (en) 2003-03-19 2003-03-19 Phospholipid esters of clofarabine derivatives
PCT/EP2004/002810 WO2004083155A2 (en) 2003-03-19 2004-03-18 Nucleotide lipid ester derivatives

Publications (2)

Publication Number Publication Date
NO20053903D0 NO20053903D0 (no) 2005-08-22
NO20053903L true NO20053903L (no) 2005-12-19

Family

ID=33031244

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053903A NO20053903L (no) 2003-03-19 2005-08-22 Nukleotidlipidesterderivater.

Country Status (21)

Country Link
US (1) US7419965B2 (enExample)
EP (2) EP1460082A1 (enExample)
JP (1) JP2006520359A (enExample)
KR (1) KR20050109939A (enExample)
CN (1) CN100369926C (enExample)
AT (1) ATE328000T1 (enExample)
AU (1) AU2004222163A1 (enExample)
CA (1) CA2519434A1 (enExample)
CY (1) CY1105572T1 (enExample)
DE (1) DE602004001047T2 (enExample)
DK (1) DK1606233T3 (enExample)
ES (1) ES2265636T3 (enExample)
MX (1) MXPA05008817A (enExample)
NO (1) NO20053903L (enExample)
NZ (1) NZ542011A (enExample)
PL (1) PL1606233T3 (enExample)
PT (1) PT1606233E (enExample)
RU (1) RU2347786C2 (enExample)
SI (1) SI1606233T1 (enExample)
WO (1) WO2004083155A2 (enExample)
ZA (1) ZA200507541B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2070938A1 (en) 2007-12-13 2009-06-17 Heidelberg Pharma AG Clofarabine dietherphospholipid derivatives
CN102079766A (zh) * 2009-11-29 2011-06-01 海南中化联合制药工业股份有限公司 一种单磷酸阿糖腺苷的制备方法
CN101709073B (zh) * 2009-12-01 2013-01-23 北京大学 核苷酸磷脂分子及脂质体及其制备方法和应用
CN103232510B (zh) * 2012-11-23 2015-12-23 北京大学 5’-氨基-2’,5’-双脱氧核苷酸磷脂分子及其制备方法和应用
US9771385B2 (en) * 2014-11-26 2017-09-26 Vascular Biogenics Ltd. Oxidized lipids
KR102371969B1 (ko) 2016-12-23 2022-03-08 주식회사 엘지에너지솔루션 배터리 모듈
US12397058B2 (en) 2018-06-26 2025-08-26 Tsrl, Inc. Metabolically stable prodrugs
WO2024059754A1 (en) * 2022-09-14 2024-03-21 Quantapore, Inc. Polythiolated linkers for stable nanoparticle suspensions and uses thereof
WO2025096481A1 (en) * 2023-10-29 2025-05-08 Maia Biotechnology, Inc. Telomere-targeting phosphatidyl-thio conjugates

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
US4751221A (en) * 1985-10-18 1988-06-14 Sloan-Kettering Institute For Cancer Research 2-fluoro-arabinofuranosyl purine nucleosides
JPS6383094A (ja) * 1986-09-27 1988-04-13 Toyo Jozo Co Ltd エ−テル型ヌクレオシド−リン脂質複合体
DE4026265A1 (de) 1990-08-20 1992-02-27 Boehringer Mannheim Gmbh Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
US5512671A (en) * 1993-02-16 1996-04-30 Wake Forest University Ether lipid-nucleoside covalent conjugates
DE4321978A1 (de) * 1993-07-01 1995-01-12 Boehringer Mannheim Gmbh Liponucleotide von Desoxynucleosiden, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel
DK0791056T3 (da) * 1994-11-12 2005-07-04 Heidelberg Pharma Gmbh Lipidopspaltende enzymkompleks
US7517858B1 (en) * 1995-06-07 2009-04-14 The Regents Of The University Of California Prodrugs of pharmaceuticals with improved bioavailability
US6670341B1 (en) * 1999-10-28 2003-12-30 Wake Forest University Health Sciences Compositions and methods for double-targeting virus infections and targeting cancer cells
US7026469B2 (en) * 2000-10-19 2006-04-11 Wake Forest University School Of Medicine Compositions and methods of double-targeting virus infections and cancer cells

Also Published As

Publication number Publication date
EP1460082A1 (en) 2004-09-22
US7419965B2 (en) 2008-09-02
MXPA05008817A (es) 2005-10-18
CN100369926C (zh) 2008-02-20
PL1606233T3 (pl) 2006-10-31
NO20053903D0 (no) 2005-08-22
WO2004083155A2 (en) 2004-09-30
ES2265636T3 (es) 2007-02-16
CA2519434A1 (en) 2004-09-30
KR20050109939A (ko) 2005-11-22
DK1606233T3 (da) 2006-09-18
EP1606233B1 (en) 2006-05-31
DE602004001047D1 (de) 2006-07-06
JP2006520359A (ja) 2006-09-07
DE602004001047T2 (de) 2007-04-19
RU2005130992A (ru) 2006-04-10
CN1771253A (zh) 2006-05-10
PT1606233E (pt) 2006-09-29
SI1606233T1 (sl) 2006-10-31
ZA200507541B (en) 2006-05-31
RU2347786C2 (ru) 2009-02-27
CY1105572T1 (el) 2010-07-28
AU2004222163A1 (en) 2004-09-30
US20060293514A1 (en) 2006-12-28
ATE328000T1 (de) 2006-06-15
WO2004083155A3 (en) 2005-03-31
NZ542011A (en) 2008-02-29
EP1606233A2 (en) 2005-12-21

Similar Documents

Publication Publication Date Title
TW200612918A (en) Lonidamine analogs
IL273422A (en) Methods and systems for extracorporeal organ treatment
AU2003220970A1 (en) Diamino-pyrimidines and their use as angiogenesis inhibitors
ATE474617T1 (de) Medizinproduktsysteme
CY1106766T1 (el) Παραγωγα πυριδινης ως αναστολεις raf κινασης
AU2003205077A1 (en) Imaging agents and methods of imaging naaladase of psma
DE602004026113D1 (de) Glp-1-verbindungen
NO20050795L (no) Forbindelser, blandinger og fremgangsmater for utnyttelse av samme
NO20052760D0 (no) Fremgangsmate for behandling av kreft og beslektede fremgangsmater.
NO20050427L (no) Carvedilolfosfatsalter og/eller solvater derav, tilsvarende preparater og/eller behandlingsfremgangsmater
DE502004002571D1 (de) Substituierte 3-pyrrolidin-indol-derivate
ATE425982T1 (de) Thienopyrimidin-derivate als kaliumkanal- inhibitoren
ATE448232T1 (de) Substituierte heterozyklen
SV2008002856A (es) 2-amino-7, 8-dihidro-6h-pirido [4,3-d] pirimidina-5-onas
NO20053903L (no) Nukleotidlipidesterderivater.
CL2004000877A1 (es) Combinacion farmaceutica que comprende 8a) melatonina y agonistas de la melatonina, y nicotina y agonistas receptores de nicotina; kit farmaceutico, y; uso en el tratamiento de insomnio, dificultades cognitivas y dificultades de memoria; kit farmaceu
EA200400197A1 (ru) Способы получения поливалентных бактериофагов для лечения бактериальных инфекций
DE50310323D1 (de) Wässrige polyurethanzubereitungen
WO2005042699A3 (en) Modified polypeptides with therapeutic activity and methods of use
WO2005089294A3 (en) Synthesis of indenoisoquinoliniums and methods of use
HRP20090513T1 (hr) S-mirtazapin, namijenjen liječenju napadaja vrućine
WO2007076320A8 (en) Compounds
IS7868A (is) Notkun á kortkólíberín-úrókortín kerfi í meðferð á bólguvaldandi sjúkdómum.
NO20044709L (no) Kombinasjonsterapi mot tumorer omfattende substituerte akryloyldistamycinderivater og rontgenbehandling

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application