NO20052991L - Kinazolinforbindelser. - Google Patents
Kinazolinforbindelser.Info
- Publication number
- NO20052991L NO20052991L NO20052991A NO20052991A NO20052991L NO 20052991 L NO20052991 L NO 20052991L NO 20052991 A NO20052991 A NO 20052991A NO 20052991 A NO20052991 A NO 20052991A NO 20052991 L NO20052991 L NO 20052991L
- Authority
- NO
- Norway
- Prior art keywords
- quinazoline
- therapy
- formula
- preparation
- methods
- Prior art date
Links
- JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical compound N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 2
- 125000006163 5-membered heteroaryl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02293239 | 2002-12-24 | ||
| PCT/GB2003/005636 WO2004058752A1 (fr) | 2002-12-24 | 2003-12-22 | Composes de quinazoline |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20052991D0 NO20052991D0 (no) | 2005-06-17 |
| NO20052991L true NO20052991L (no) | 2005-07-19 |
Family
ID=32668916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20052991A NO20052991L (no) | 2002-12-24 | 2005-06-17 | Kinazolinforbindelser. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7407946B2 (fr) |
| EP (1) | EP1575946A1 (fr) |
| JP (1) | JP2006516138A (fr) |
| KR (1) | KR20050087863A (fr) |
| CN (1) | CN1753889A (fr) |
| AU (1) | AU2003290322A1 (fr) |
| BR (1) | BR0317680A (fr) |
| CA (1) | CA2508921A1 (fr) |
| MX (1) | MXPA05006920A (fr) |
| NO (1) | NO20052991L (fr) |
| WO (1) | WO2004058752A1 (fr) |
| ZA (1) | ZA200504828B (fr) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1847539T1 (sl) * | 2002-12-24 | 2010-01-29 | Astrazeneca Ab | Kinazolinski derivati |
| CL2004000797A1 (es) * | 2003-04-16 | 2005-05-27 | Astrazeneca Ab | Compuestos derivados de quinazolina, inhibidores de aurora quinasa; procedimiento de preparacion; composicion farmaceutica; y su uso para preparar un medicamento para tratar cancer colorrectal, de mama, de pulmon, de prostata, de vejiga, renal o panc |
| JP2006526599A (ja) * | 2003-06-02 | 2006-11-24 | アストラゼネカ アクチボラグ | 癌のような増殖性疾患の治療のためのオーロラキナーゼインヒビターとしての（３−（（キナゾリン−４−イル）アミノ）−１ｈ−ピラゾール−１−イル）アセトアミド誘導体及び関連化合物 |
| US8153643B2 (en) | 2004-10-12 | 2012-04-10 | Astrazeneca Ab | Quinazoline derivatives |
| EP1812439B2 (fr) | 2004-10-15 | 2017-12-06 | Takeda Pharmaceutical Company Limited | Inhibiteurs de kinase |
| US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| EP1785420A1 (fr) * | 2005-11-14 | 2007-05-16 | 4Sc Ag | Analogues de thiazole et leurs utilisation |
| WO2007099323A2 (fr) * | 2006-03-02 | 2007-09-07 | Astrazeneca Ab | Dérivés de la quinoline |
| UY30183A1 (es) | 2006-03-02 | 2007-10-31 | Astrazeneca Ab | Derivados de quinolina |
| US20090042910A1 (en) * | 2006-03-02 | 2009-02-12 | Frederic Henri Jung | Quinoline derivatives for treating cancer |
| WO2007113548A1 (fr) * | 2006-04-06 | 2007-10-11 | Astrazeneca Ab | Dérivés de naphtyridine |
| US20070258976A1 (en) * | 2006-05-04 | 2007-11-08 | Ward Keith W | Combination Therapy for Diseases Involving Angiogenesis |
| GB0609617D0 (en) | 2006-05-16 | 2006-06-21 | Astrazeneca Ab | Process & intermediate |
| EA200970361A1 (ru) | 2006-10-09 | 2010-02-26 | Такеда Фармасьютикал Компани Лимитед | Ингибиторы киназы |
| EP2149565A1 (fr) | 2008-07-24 | 2010-02-03 | Bayer Schering Pharma AG | Dérivés de chinazoline substitués par du sulfonamide en tant que modulateurs d'immunité pour le traitement de inflammations et allergies |
| ES2559209T3 (es) | 2010-04-14 | 2016-02-11 | Bristol-Myers Squibb Company | Nuevos activadores de la glucocinasa y métodos de uso de los mismos |
| CA3142576A1 (fr) * | 2011-01-21 | 2012-07-26 | Basilea Pharmaceutica Ag | Utilisation du bubr1 comme biomarqueur de reponse medicamenteuse aux furazanobenzimidazoles |
| EP2956138B1 (fr) | 2013-02-15 | 2022-06-22 | Kala Pharmaceuticals, Inc. | Composés thérapeutiques et utilisations de ceux-ci |
| US9688688B2 (en) | 2013-02-20 | 2017-06-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof |
| ES2831625T3 (es) | 2013-02-20 | 2021-06-09 | Kala Pharmaceuticals Inc | Compuestos terapéuticos y sus usos |
| US9890173B2 (en) | 2013-11-01 | 2018-02-13 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| MX355330B (es) | 2013-11-01 | 2018-04-16 | Kala Pharmaceuticals Inc | Formas cristalinas de compuestos terapeuticos y sus usos. |
| CA3036340A1 (fr) | 2016-09-08 | 2018-03-15 | Kala Pharmaceuticals, Inc. | Formes cristallines de composes therapeutiques et leurs utilisations |
| KR20190051010A (ko) | 2016-09-08 | 2019-05-14 | 칼라 파마슈티컬스, 인크. | 치료 화합물의 결정형 및 그의 용도 |
| AU2017324713B2 (en) | 2016-09-08 | 2020-08-13 | KALA BIO, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9922171D0 (en) | 1999-09-21 | 1999-11-17 | Zeneca Ltd | Chemical compounds |
| CA2384291A1 (fr) | 1999-09-21 | 2001-03-29 | Astrazeneca Ab | Derives de quinazoline et leur utilisation comme produits pharmaceutiques |
| NZ522696A (en) | 2000-06-28 | 2004-08-27 | Astrazeneca Ab | Substituted quinazoline derivatives and their use as inhibitors |
| EP1408980A4 (fr) * | 2001-06-21 | 2004-10-20 | Ariad Pharma Inc | Nouvelles quinazolines et leur utilisation |
| ATE412657T1 (de) * | 2002-12-24 | 2008-11-15 | Astrazeneca Ab | Therapeutische quinazolin-derivate |
| SI1847539T1 (sl) * | 2002-12-24 | 2010-01-29 | Astrazeneca Ab | Kinazolinski derivati |
-
2003
- 2003-12-22 US US10/539,481 patent/US7407946B2/en not_active Expired - Fee Related
- 2003-12-22 CA CA002508921A patent/CA2508921A1/fr not_active Abandoned
- 2003-12-22 MX MXPA05006920A patent/MXPA05006920A/es not_active Application Discontinuation
- 2003-12-22 JP JP2004563353A patent/JP2006516138A/ja active Pending
- 2003-12-22 KR KR1020057012019A patent/KR20050087863A/ko not_active Application Discontinuation
- 2003-12-22 AU AU2003290322A patent/AU2003290322A1/en not_active Abandoned
- 2003-12-22 BR BR0317680-0A patent/BR0317680A/pt not_active Application Discontinuation
- 2003-12-22 WO PCT/GB2003/005636 patent/WO2004058752A1/fr active Application Filing
- 2003-12-22 CN CNA2003801098990A patent/CN1753889A/zh active Pending
- 2003-12-22 EP EP03782681A patent/EP1575946A1/fr not_active Withdrawn
-
2005
- 2005-06-13 ZA ZA200504828A patent/ZA200504828B/en unknown
- 2005-06-17 NO NO20052991A patent/NO20052991L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050087863A (ko) | 2005-08-31 |
| AU2003290322A1 (en) | 2004-07-22 |
| JP2006516138A (ja) | 2006-06-22 |
| MXPA05006920A (es) | 2006-02-10 |
| NO20052991D0 (no) | 2005-06-17 |
| US20060058523A1 (en) | 2006-03-16 |
| BR0317680A (pt) | 2005-11-29 |
| CN1753889A (zh) | 2006-03-29 |
| US7407946B2 (en) | 2008-08-05 |
| WO2004058752A1 (fr) | 2004-07-15 |
| ZA200504828B (en) | 2008-02-27 |
| CA2508921A1 (fr) | 2004-07-15 |
| EP1575946A1 (fr) | 2005-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |