NO20052859L - Fremgangsmate for fremstilling av resperidon og intermediater derav - Google Patents
Fremgangsmate for fremstilling av resperidon og intermediater deravInfo
- Publication number
- NO20052859L NO20052859L NO20052859A NO20052859A NO20052859L NO 20052859 L NO20052859 L NO 20052859L NO 20052859 A NO20052859 A NO 20052859A NO 20052859 A NO20052859 A NO 20052859A NO 20052859 L NO20052859 L NO 20052859L
- Authority
- NO
- Norway
- Prior art keywords
- resperidone
- intermediates
- preparation
- enriched
- isomeroxime
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42572702P | 2002-11-13 | 2002-11-13 | |
PCT/EP2003/012504 WO2004043923A1 (fr) | 2002-11-13 | 2003-11-07 | Procede de fabrication de la risperidone et des intermediaires associes |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20052859D0 NO20052859D0 (no) | 2005-06-13 |
NO20052859L true NO20052859L (no) | 2005-08-05 |
Family
ID=32313043
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20052859A NO20052859L (no) | 2002-11-13 | 2005-06-13 | Fremgangsmate for fremstilling av resperidon og intermediater derav |
Country Status (9)
Country | Link |
---|---|
US (2) | US7405298B2 (fr) |
EP (1) | EP1560814A1 (fr) |
CN (1) | CN100390146C (fr) |
AR (1) | AR041954A1 (fr) |
AU (1) | AU2003288017A1 (fr) |
HR (1) | HRP20050424A2 (fr) |
NO (1) | NO20052859L (fr) |
WO (1) | WO2004043923A1 (fr) |
ZA (1) | ZA200503698B (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA200603113B (en) * | 2003-09-26 | 2007-08-29 | Jubilant Organosys Ltd | Process for the preparation of risperidone |
WO2009077551A1 (fr) * | 2007-12-18 | 2009-06-25 | Janssen Pharmaceutica Nv | Procédé de préparation de la rispéridone |
US8772345B2 (en) | 2011-08-03 | 2014-07-08 | Southwest Research Institute | Oximes for treatment of peripheral and central nervous system exposure to acetyl cholinesterase inhibitors |
US8653108B1 (en) | 2011-08-03 | 2014-02-18 | Southwest Research Institute | Oximes for treatment of peripheral and central nervous system exposure to acetyl cholinesterase inhibitors |
US9162983B2 (en) | 2013-05-22 | 2015-10-20 | Southwest Research Institute | Reactivators of organophosphorous inhibited acetylcholinesterase |
CN104557918A (zh) * | 2014-12-12 | 2015-04-29 | 瑞阳制药有限公司 | 苯并异恶唑类抗精神病药利培酮的制备方法 |
CN107422055A (zh) * | 2017-07-27 | 2017-12-01 | 天津药物研究院药业有限责任公司 | 一种利培酮原料或制剂中杂质的检测方法 |
CN108445101B (zh) * | 2018-03-16 | 2021-01-01 | 安徽新世纪药业有限公司 | 一种利培酮口服溶液有关物质的检测方法 |
CN109438443A (zh) * | 2018-12-24 | 2019-03-08 | 浙江工业大学上虞研究院有限公司 | 利培酮的制备方法 |
CN111777601B (zh) * | 2020-05-23 | 2021-07-16 | 白银京宇新药业有限公司 | 一种6-氟-3-(4-哌啶基)-1,2苯并异噁唑盐酸盐的制备方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3946022A (en) * | 1974-03-04 | 1976-03-23 | Richardson-Merrell Inc. | Piperidine derivatives |
US4335127A (en) | 1979-01-08 | 1982-06-15 | Janssen Pharmaceutica, N.V. | Piperidinylalkyl quinazoline compounds, composition and method of use |
US4342870A (en) | 1980-03-28 | 1982-08-03 | Janssen Pharmaceutica N.V. | Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives |
US4408054A (en) * | 1981-11-12 | 1983-10-04 | Hoechst-Roussel Pharmaceuticals Inc. | Oximes of 4-benzoyl-piperidines |
US4804663A (en) | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
CA2000786C (fr) | 1988-11-07 | 1999-01-26 | Cornelus G. M. Janssen | 3-piperidinyl-1,2-benzisoxazoles |
GB9008850D0 (en) * | 1990-04-19 | 1990-06-13 | Janssen Pharmaceutica Nv | Novel 2,9-disubstituted-4h-pyridol(1,2-a)pyrimidin-4-ones |
ES2050069B1 (es) * | 1992-07-10 | 1994-12-16 | Vita Invest Sa | Procedimiento para la obtencion de 3-(2-(4-(6-fluoro-1,2-benzisoxazol-3-il)piperidino)etil)-2-metil-6,7,8,9-tetrahidro-4h-pirido(1,2-a) pirimidin-4-ona. |
ES2074966B1 (es) | 1994-02-11 | 1996-06-16 | Vita Invest Sa | Procedimiento para la obtencion de 3-(2-(4-(6-fluoro-benzo(d)isoxazol-3-il)piperidin-1-il)-etil)-2-metil-6,7,8,9-tetrahidro-4h-pirido-(1,2-a)pirimidin-4-ona. |
CZ295402B6 (cs) | 2000-05-05 | 2005-08-17 | Rpg Life Sciences Limited | Způsob přípravy antipsychotického 3-[2-[4-(6-fluor-1,2-benzizoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2,-a]pyrimidin-4-onu |
US20020115672A1 (en) | 2000-08-08 | 2002-08-22 | Barnaba Krochmal | Preparation of risperidone |
EP1982980A1 (fr) | 2000-08-14 | 2008-10-22 | Teva Pharmaceutical Industries Ltd. | Forme cristalline de la rispéridone |
HU227118B1 (en) | 2001-11-13 | 2010-07-28 | Egis Gyogyszergyar Nyilvanosan | Process for the preparation of 3-{2-[4-(6-fluoro-1,2-benzizoxazol-3-yl)-1-piperidinyl]-ethyl}-6,7,8,9-tetrahydro-2-methyl-4h-pyrido[1,2-a]pyrimidin-4-one |
MXPA06007654A (es) * | 2003-12-31 | 2006-09-04 | Warner Lambert Co | Derivados de piperidina n-sustituidos. |
-
2003
- 2003-11-07 EP EP03779870A patent/EP1560814A1/fr not_active Withdrawn
- 2003-11-07 AU AU2003288017A patent/AU2003288017A1/en not_active Abandoned
- 2003-11-07 CN CNB2003801049621A patent/CN100390146C/zh not_active Expired - Fee Related
- 2003-11-07 WO PCT/EP2003/012504 patent/WO2004043923A1/fr not_active Application Discontinuation
- 2003-11-13 AR ARP030104179A patent/AR041954A1/es unknown
- 2003-11-13 US US10/705,926 patent/US7405298B2/en not_active Expired - Fee Related
-
2005
- 2005-05-09 ZA ZA200503698A patent/ZA200503698B/en unknown
- 2005-05-12 HR HR20050424A patent/HRP20050424A2/xx not_active Application Discontinuation
- 2005-06-13 NO NO20052859A patent/NO20052859L/no not_active Application Discontinuation
-
2008
- 2008-06-18 US US12/141,596 patent/US20080262227A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
HRP20050424A2 (en) | 2006-08-31 |
CN100390146C (zh) | 2008-05-28 |
WO2004043923A1 (fr) | 2004-05-27 |
US7405298B2 (en) | 2008-07-29 |
AR041954A1 (es) | 2005-06-01 |
AU2003288017A1 (en) | 2004-06-03 |
NO20052859D0 (no) | 2005-06-13 |
EP1560814A1 (fr) | 2005-08-10 |
US20080262227A1 (en) | 2008-10-23 |
CN1720228A (zh) | 2006-01-11 |
ZA200503698B (en) | 2006-08-30 |
US20040097523A1 (en) | 2004-05-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |