NO20052167L - Hjelpemidler eller preventivmidler mot urineringsfrekvens eller urinkontinens og morfinanderivater med nitrogenholdig heterocyklisk gruppe - Google Patents
Hjelpemidler eller preventivmidler mot urineringsfrekvens eller urinkontinens og morfinanderivater med nitrogenholdig heterocyklisk gruppeInfo
- Publication number
- NO20052167L NO20052167L NO20052167A NO20052167A NO20052167L NO 20052167 L NO20052167 L NO 20052167L NO 20052167 A NO20052167 A NO 20052167A NO 20052167 A NO20052167 A NO 20052167A NO 20052167 L NO20052167 L NO 20052167L
- Authority
- NO
- Norway
- Prior art keywords
- urinary incontinence
- diseases
- nitrogen
- contraceptives
- urination
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Morfinanderivat av formel (I), hvor R1er metyl, syklopropylmetyl eller lignende; R2 og R3 er hydroksy, metoksy, acetoksy eller lignende; både Y og Z er valensbindinger, -C(=O)- eller lignende; X er C2-C5-karbonkjede (ett av karbonatomene kan være substituert med oksygen, svovel eller nitrogen) som utgjør en del av ringstrukturen eller lignende; (R4)k er substituert eller ikke-substituert benzenkondensert ring, karbonylgruppe eller lignende; R9 er hydrogen eller lignende; R10 og R11 er sammenbundet til å representere -O- eller lignende, og R6 er hydrogen eller lignende, eller et farmasøytisk akseptabelt syreaddisjonssalt derav. Det er også tilveiebrakt et terapeutisk eller profylaktisk middel for urineringshyppighet eller urininkontinens, innbefattende som en effektiv bestanddel, morfinanderivatet eller det farmasøytisk akseptable syreaddisjonssaltet derav; en fremgangsmåte for terapi eller profylakse av sykdommene, og anvendelse for sykdommene. Forbindelsene ifølge oppfinnelsen er nyttige som et nytt terapeutisk eller profylaktisk middel for urineringshyppighet eller urininkontinens, er frie for bivirkninger, og nyttige for terapi eller profylakse av sykdommene og for anvendelse for sykdommene.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002295616 | 2002-10-09 | ||
PCT/JP2003/012890 WO2004033457A1 (ja) | 2002-10-09 | 2003-10-08 | 頻尿もしくは尿失禁の治療または予防剤および含窒素環状置換基を有するモルヒナン誘導体 |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20052167L true NO20052167L (no) | 2005-06-16 |
Family
ID=32089217
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20052167A NO20052167L (no) | 2002-10-09 | 2005-05-03 | Hjelpemidler eller preventivmidler mot urineringsfrekvens eller urinkontinens og morfinanderivater med nitrogenholdig heterocyklisk gruppe |
Country Status (17)
Country | Link |
---|---|
US (1) | US7320984B2 (no) |
EP (1) | EP1555266B1 (no) |
JP (1) | JP4016986B2 (no) |
KR (1) | KR101060629B1 (no) |
CN (1) | CN100537573C (no) |
AU (1) | AU2003272944B2 (no) |
BR (1) | BR0314754A (no) |
CA (1) | CA2501389C (no) |
ES (1) | ES2479042T3 (no) |
HK (1) | HK1079786B (no) |
IL (1) | IL166944A (no) |
MA (1) | MA27454A1 (no) |
MX (1) | MXPA05003723A (no) |
NO (1) | NO20052167L (no) |
NZ (1) | NZ539199A (no) |
WO (1) | WO2004033457A1 (no) |
ZA (1) | ZA200502650B (no) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060177381A1 (en) * | 2002-02-15 | 2006-08-10 | Howard Brooks-Korn | Opiopathies |
GB0210397D0 (en) * | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
KR101233289B1 (ko) * | 2004-03-30 | 2013-02-14 | 도레이 카부시키가이샤 | 지양제 |
AR053098A1 (es) | 2004-11-04 | 2007-04-25 | Toray Industries | Analgesico derivado de morfinano |
JPWO2006104280A1 (ja) * | 2005-03-31 | 2008-09-11 | 武田薬品工業株式会社 | 糖尿病の予防・治療剤 |
ES2464593T3 (es) | 2005-11-09 | 2014-06-03 | Toray Industries, Inc. | Agente terapéutico o profiláctico para trastornos funcionales digestivos |
US8106065B2 (en) * | 2005-12-21 | 2012-01-31 | Toray Industries, Inc. | Antitussive agent |
CA2687955C (en) | 2007-05-21 | 2015-06-30 | Toray Industries, Inc. | Crystalline micropowder particles |
CA2687956C (en) | 2007-05-21 | 2015-03-31 | Toray Industries, Inc. | Method for producing pharmaceutical tablet |
RU2472539C2 (ru) | 2007-08-06 | 2013-01-20 | Аллерган, Инк. | Способы и устройства для доставки препарата десмопрессина |
LT2712622T (lt) * | 2008-05-21 | 2016-09-26 | Ferring B.V. | Burnoje disperguojamas desmopresinas, skirtas nikturijos netrikdomo miego pirminio periodo pailginimui |
US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
JP5648480B2 (ja) * | 2008-10-24 | 2015-01-07 | 東レ株式会社 | 4,5−エポキシモルヒナン誘導体を含有する安定な錠剤 |
WO2010083384A2 (en) * | 2009-01-16 | 2010-07-22 | Virginia Commonwealth University | Non-peptidyl, potent, and selective mu opioid receptor antagonists |
US8623888B2 (en) * | 2009-07-15 | 2014-01-07 | Mallinckrodt Llc | 3-oxy-hydromorphone derivatives |
EP2995614B8 (en) | 2010-06-11 | 2018-03-28 | Rhodes Technologies Inc. | Transition metal-catalyzed processes for the preparation of n-allyl compounds and use thereof |
EP3458061B1 (en) * | 2016-05-19 | 2023-01-18 | Virginia Commonwealth University | Potent and selective mu opioid receptor modulators |
AU2019229892A1 (en) | 2018-03-08 | 2020-09-03 | University Of Kansas | Treatment of demyelinating diseases |
CN109970747B (zh) * | 2019-05-05 | 2020-07-24 | 潍坊科技学院 | 一种制备10α-羟基纳呋拉啡的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3318885A (en) * | 1965-07-21 | 1967-05-09 | American Cyanamid Co | Substituted 6-amino-6, 14-endoethen-ocodides and morphides |
JP2525552B2 (ja) * | 1992-01-23 | 1996-08-21 | 東レ株式会社 | モルヒナン誘導体および医薬用途 |
CA2143864C (en) | 1993-07-23 | 2006-01-24 | Hiroshi Nagase | Morphinan derivatives and pharmaceutical use thereof |
AU5090796A (en) * | 1995-03-03 | 1996-09-23 | Algos Pharmaceutical Corporation | Use of dextromethorphan or dextrorphan for the treatment of urinary incontinence |
EP1203771A4 (en) * | 1999-07-19 | 2003-07-30 | Toray Industries | HEALING OR PREVENTIVE AGENTS FOR THE TREATMENT OF FREQUENCY OF URINATION AND CONTINUITY |
WO2002080918A1 (fr) * | 2001-04-02 | 2002-10-17 | Toray Industries, Inc. | Agent therapeutique ou prophylactique en cas de miction frequente ou d'incontinence urinaire |
-
2003
- 2003-10-08 WO PCT/JP2003/012890 patent/WO2004033457A1/ja active Application Filing
- 2003-10-08 CN CNB2003801009713A patent/CN100537573C/zh not_active Expired - Fee Related
- 2003-10-08 AU AU2003272944A patent/AU2003272944B2/en not_active Ceased
- 2003-10-08 KR KR1020057006096A patent/KR101060629B1/ko not_active IP Right Cessation
- 2003-10-08 BR BR0314754-1A patent/BR0314754A/pt not_active Application Discontinuation
- 2003-10-08 NZ NZ539199A patent/NZ539199A/en not_active IP Right Cessation
- 2003-10-08 ES ES03754030.9T patent/ES2479042T3/es not_active Expired - Lifetime
- 2003-10-08 MX MXPA05003723A patent/MXPA05003723A/es active IP Right Grant
- 2003-10-08 US US10/530,664 patent/US7320984B2/en not_active Expired - Fee Related
- 2003-10-08 EP EP03754030.9A patent/EP1555266B1/en not_active Expired - Lifetime
- 2003-10-08 JP JP2004542845A patent/JP4016986B2/ja not_active Expired - Fee Related
- 2003-10-08 CA CA2501389A patent/CA2501389C/en not_active Expired - Fee Related
-
2005
- 2005-02-16 IL IL166944A patent/IL166944A/en not_active IP Right Cessation
- 2005-04-01 ZA ZA200502650A patent/ZA200502650B/en unknown
- 2005-04-13 MA MA28218A patent/MA27454A1/fr unknown
- 2005-05-03 NO NO20052167A patent/NO20052167L/no not_active Application Discontinuation
- 2005-12-29 HK HK05112093.6A patent/HK1079786B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
MA27454A1 (fr) | 2005-07-01 |
JPWO2004033457A1 (ja) | 2006-04-27 |
BR0314754A (pt) | 2005-07-26 |
CN1703415A (zh) | 2005-11-30 |
HK1079786A1 (en) | 2006-04-13 |
CA2501389A1 (en) | 2004-04-22 |
US7320984B2 (en) | 2008-01-22 |
ES2479042T3 (es) | 2014-07-23 |
EP1555266B1 (en) | 2014-05-21 |
EP1555266A4 (en) | 2006-12-06 |
KR101060629B1 (ko) | 2011-08-31 |
NZ539199A (en) | 2008-09-26 |
AU2003272944B2 (en) | 2009-11-12 |
US20060040970A1 (en) | 2006-02-23 |
MXPA05003723A (es) | 2005-09-30 |
HK1079786B (zh) | 2010-03-12 |
CA2501389C (en) | 2013-01-08 |
CN100537573C (zh) | 2009-09-09 |
WO2004033457A1 (ja) | 2004-04-22 |
AU2003272944A1 (en) | 2004-05-04 |
EP1555266A1 (en) | 2005-07-20 |
KR20050056232A (ko) | 2005-06-14 |
JP4016986B2 (ja) | 2007-12-05 |
IL166944A (en) | 2010-11-30 |
ZA200502650B (en) | 2006-06-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |