NO20051969L - Nukleosidderivater for behandling av hepatitt C virusinfeksjon. - Google Patents
Nukleosidderivater for behandling av hepatitt C virusinfeksjon.Info
- Publication number
- NO20051969L NO20051969L NO20051969A NO20051969A NO20051969L NO 20051969 L NO20051969 L NO 20051969L NO 20051969 A NO20051969 A NO 20051969A NO 20051969 A NO20051969 A NO 20051969A NO 20051969 L NO20051969 L NO 20051969L
- Authority
- NO
- Norway
- Prior art keywords
- hepatitis
- treatment
- virus infection
- nucleoside derivatives
- nucleoside
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/167—Purine radicals with ribosyl as the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/14—Pyrrolo-pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41522202P | 2002-09-30 | 2002-09-30 | |
US44316903P | 2003-01-29 | 2003-01-29 | |
PCT/US2003/031433 WO2004028481A2 (en) | 2002-09-30 | 2003-09-30 | Nucleoside derivatives for treating hepatitis c virus infection |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20051969L true NO20051969L (no) | 2005-05-24 |
Family
ID=32045309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20051969A NO20051969L (no) | 2002-09-30 | 2005-04-22 | Nukleosidderivater for behandling av hepatitt C virusinfeksjon. |
Country Status (13)
Country | Link |
---|---|
US (2) | US7425547B2 (es) |
EP (1) | EP1572097A4 (es) |
JP (1) | JP2006505537A (es) |
KR (1) | KR20050059199A (es) |
AU (1) | AU2003279797B2 (es) |
CA (1) | CA2499253A1 (es) |
EA (1) | EA200500584A1 (es) |
MX (1) | MXPA05003400A (es) |
NO (1) | NO20051969L (es) |
NZ (1) | NZ538457A (es) |
PL (1) | PL376043A1 (es) |
TW (1) | TW200418498A (es) |
WO (1) | WO2004028481A2 (es) |
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY164523A (en) | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
EA200601591A1 (ru) * | 2000-05-26 | 2007-02-27 | Айденикс (Кайман) Лимитед | Применение рибонуклеозидных соединений для лечения флавивирусных и пестивирусных инфекций |
WO2003026589A2 (en) * | 2001-09-28 | 2003-04-03 | Idenix (Cayman) Limited | Methods and compositions for treating hepatitis c virus using 4'-modified nucleosides |
WO2004003138A2 (en) * | 2002-06-27 | 2004-01-08 | Merck & Co., Inc. | Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase |
BR0312278A (pt) * | 2002-06-28 | 2007-06-19 | Idenix Cayman Ltd | éster 2'-c-metil-3'-o-l-valina de ribofuranosil citidina para tratamento de infecções por flaviviridae |
US7608600B2 (en) * | 2002-06-28 | 2009-10-27 | Idenix Pharmaceuticals, Inc. | Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections |
AU2003256619A1 (en) * | 2002-07-24 | 2004-02-09 | Isis Pharmaceuticals, Inc. | Pyrrolopyrimidine thionucleoside analogs as antivirals |
US7094768B2 (en) | 2002-09-30 | 2006-08-22 | Genelabs Technologies, Inc. | Nucleoside derivatives for treating hepatitis C virus infection |
AU2003279797B2 (en) * | 2002-09-30 | 2009-10-22 | Genelabs Technologies, Inc. | Nucleoside derivatives for treating hepatitis C virus infection |
SI1576138T1 (sl) | 2002-11-15 | 2017-07-31 | Idenix Pharmaceuticals Llc | 2'-metil nukleozidi v kombinaciji z interferon in flaviviridae mutacijo |
JP2006514038A (ja) * | 2002-12-23 | 2006-04-27 | イデニクス(ケイマン)リミテツド | 3’−ヌクレオシドプロドラッグの生産方法 |
US7799908B2 (en) | 2003-01-15 | 2010-09-21 | Valeant Pharmaceuticals North America | Synthesis and use of 2′-substituted-N6 -modified nucleosides |
KR20060084845A (ko) | 2003-07-25 | 2006-07-25 | 이데닉스 (케이만) 리미티드 | C형 간염을 포함하는 플라비비리다에를 치료하기 위한퓨린 뉴클레오시드 유사체 |
US7151089B2 (en) | 2003-10-27 | 2006-12-19 | Genelabs Technologies, Inc. | Nucleoside compounds for treating viral infections |
CA2543116A1 (en) | 2003-10-27 | 2005-05-19 | Genelabs Technologies, Inc. | Methods for preparing 7-(2'-substituted-.szlig.-d-ribofuranosyl)-4-(nr2r3)-5-(substituted ethyn-1-yl)-pyrrolo[2,3-d]pyrimidine derivatives |
EP1687321A1 (en) | 2003-10-27 | 2006-08-09 | Genelabs Technologies, Inc. | Nucleoside compounds for treating viral infections |
KR20060096487A (ko) | 2003-10-27 | 2006-09-11 | 진랩스 테크놀러지스, 인크. | 바이러스 감염증들을 치료하기 위한 뉴클레오시드 화합물 |
US7202223B2 (en) | 2003-10-27 | 2007-04-10 | Genelabs Technologies, Inc. | Nucleoside compounds for treating viral infections |
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JP2008501758A (ja) | 2004-06-09 | 2008-01-24 | グラクソ グループ リミテッド | ピロロピリジン誘導体 |
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EP1773355B1 (en) | 2004-06-24 | 2014-06-25 | Merck Sharp & Dohme Corp. | Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection |
KR20070073805A (ko) * | 2004-09-24 | 2007-07-10 | 이데닉스 (케이만) 리미티드 | 플라비바이러스, 페스티바이러스 및 헤파시바이러스를치료하기 위한 방법 및 조성물 |
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TWI406664B (zh) * | 2006-03-30 | 2013-09-01 | Univ Kyoto | 硫氧還蛋白(thioredoxin)產生促進劑 |
GB0609492D0 (en) | 2006-05-15 | 2006-06-21 | Angeletti P Ist Richerche Bio | Therapeutic agents |
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JP2010533699A (ja) | 2007-07-17 | 2010-10-28 | イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー | C型肝炎感染症の治療のための大環状インドール誘導体 |
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WO2010082050A1 (en) | 2009-01-16 | 2010-07-22 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | Macrocyclic and 7-aminoalkyl-substituted benzoxazocines for treatment of hepatitis c infections |
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WO2012082436A2 (en) * | 2010-12-03 | 2012-06-21 | Epizyme, Inc. | Modulators of histone methyltransferase, and methods of use thereof |
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JP2016517426A (ja) | 2013-03-15 | 2016-06-16 | エピザイム,インコーポレイティド | 置換プリン化合物の合成方法 |
CN106061984A (zh) | 2014-02-13 | 2016-10-26 | 配体药物公司 | 前药化合物及其用途 |
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JP2018523665A (ja) | 2015-08-06 | 2018-08-23 | キメリックス インコーポレイテッド | 抗ウイルス剤として有用なピロロピリミジンヌクレオシドおよびその類縁体 |
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CA3087932A1 (en) | 2018-01-09 | 2019-07-18 | Ligand Pharmaceuticals, Inc. | Acetal compounds and therapeutic uses thereof |
US20240165144A1 (en) * | 2019-10-16 | 2024-05-23 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for modulating innate immune signaling pathways |
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JPS6160695A (ja) * | 1984-08-30 | 1986-03-28 | Arakawa Chiyoutarou Kk | 新規なn↑6−置換アデノシン誘導体及びその製造法並びにそれを有効成分とする降圧薬 |
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DE4141454A1 (de) * | 1991-11-25 | 1993-05-27 | Schering Ag | Neues verfahren zur herstellung von 2-fluorpurin-derivaten |
CA2129105A1 (en) * | 1992-02-12 | 1993-08-19 | Michael J. Conrad | Applications of fluorescent n-nucleosides and fluorescent structural analogs of n-nucleosides |
DK62592D0 (es) * | 1992-05-14 | 1992-05-14 | Novo Nordisk As | |
JPH08506343A (ja) * | 1993-02-03 | 1996-07-09 | ジェンシア・インコーポレイテッド | リキソフラノシル誘導体を含むアデノシンキナーゼ阻害物質 |
JPH09506333A (ja) * | 1993-09-17 | 1997-06-24 | ギリアード サイエンシーズ,インコーポレイテッド | 治療化合物の投薬方法 |
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BR0312278A (pt) | 2002-06-28 | 2007-06-19 | Idenix Cayman Ltd | éster 2'-c-metil-3'-o-l-valina de ribofuranosil citidina para tratamento de infecções por flaviviridae |
AU2003279797B2 (en) | 2002-09-30 | 2009-10-22 | Genelabs Technologies, Inc. | Nucleoside derivatives for treating hepatitis C virus infection |
US7094768B2 (en) | 2002-09-30 | 2006-08-22 | Genelabs Technologies, Inc. | Nucleoside derivatives for treating hepatitis C virus infection |
US7799908B2 (en) | 2003-01-15 | 2010-09-21 | Valeant Pharmaceuticals North America | Synthesis and use of 2′-substituted-N6 -modified nucleosides |
-
2003
- 2003-09-30 AU AU2003279797A patent/AU2003279797B2/en not_active Expired - Fee Related
- 2003-09-30 TW TW092127047A patent/TW200418498A/zh unknown
- 2003-09-30 JP JP2004540353A patent/JP2006505537A/ja not_active Revoked
- 2003-09-30 PL PL03376043A patent/PL376043A1/xx not_active Application Discontinuation
- 2003-09-30 WO PCT/US2003/031433 patent/WO2004028481A2/en active Application Filing
- 2003-09-30 KR KR1020057005196A patent/KR20050059199A/ko not_active Application Discontinuation
- 2003-09-30 MX MXPA05003400A patent/MXPA05003400A/es active IP Right Grant
- 2003-09-30 US US10/676,956 patent/US7425547B2/en not_active Expired - Fee Related
- 2003-09-30 CA CA002499253A patent/CA2499253A1/en not_active Abandoned
- 2003-09-30 EP EP03773127A patent/EP1572097A4/en not_active Withdrawn
- 2003-09-30 EA EA200500584A patent/EA200500584A1/ru unknown
- 2003-09-30 NZ NZ538457A patent/NZ538457A/en unknown
-
2005
- 2005-04-22 NO NO20051969A patent/NO20051969L/no not_active Application Discontinuation
-
2008
- 2008-05-19 US US12/123,310 patent/US7629320B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US7629320B2 (en) | 2009-12-08 |
KR20050059199A (ko) | 2005-06-17 |
WO2004028481A3 (en) | 2005-10-20 |
PL376043A1 (en) | 2005-12-12 |
AU2003279797A1 (en) | 2004-04-19 |
EP1572097A4 (en) | 2010-02-17 |
JP2006505537A (ja) | 2006-02-16 |
MXPA05003400A (es) | 2005-06-22 |
NZ538457A (en) | 2008-04-30 |
EP1572097A2 (en) | 2005-09-14 |
AU2003279797B2 (en) | 2009-10-22 |
US20080249060A1 (en) | 2008-10-09 |
TW200418498A (en) | 2004-10-01 |
WO2004028481A2 (en) | 2004-04-08 |
EA200500584A1 (ru) | 2006-02-24 |
US7425547B2 (en) | 2008-09-16 |
CA2499253A1 (en) | 2004-04-08 |
US20040147464A1 (en) | 2004-07-29 |
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