NO20051296L - Partielle og fullstendige agonister av A1-adenosinreseptorer - Google Patents

Partielle og fullstendige agonister av A1-adenosinreseptorer

Info

Publication number
NO20051296L
NO20051296L NO20051296A NO20051296A NO20051296L NO 20051296 L NO20051296 L NO 20051296L NO 20051296 A NO20051296 A NO 20051296A NO 20051296 A NO20051296 A NO 20051296A NO 20051296 L NO20051296 L NO 20051296L
Authority
NO
Norway
Prior art keywords
sup
optionally substituted
cycloalkyl
hydrogen
partial
Prior art date
Application number
NO20051296A
Other languages
English (en)
Inventor
Jeff A Zablocki
Elfatih O Elzein
Venkata Palle
Xiaofen Li
Original Assignee
Cv Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cv Therapeutics Inc filed Critical Cv Therapeutics Inc
Publication of NO20051296L publication Critical patent/NO20051296L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Transplantation (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Tilkjennegitt er nye forbindelser som er partielle eller fullstendige A1-adenosinreseptoragonister som er nyttige for behandling av ulike sykdomstilstander, spesielt supraventrikulære takykardier, kvalme, angina, hjerteinfarkt og hyperlipiden-fi.
NO20051296A 2002-08-15 2005-03-14 Partielle og fullstendige agonister av A1-adenosinreseptorer NO20051296L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40371202P 2002-08-15 2002-08-15
US45009403P 2003-02-25 2003-02-25
PCT/US2003/025629 WO2004016635A2 (en) 2002-08-15 2003-08-15 Partial and full agonists of a1 adenosine receptors

Publications (1)

Publication Number Publication Date
NO20051296L true NO20051296L (no) 2005-05-13

Family

ID=31891396

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20051296A NO20051296L (no) 2002-08-15 2005-03-14 Partielle og fullstendige agonister av A1-adenosinreseptorer

Country Status (15)

Country Link
US (2) US7022681B2 (no)
EP (1) EP1537133B1 (no)
JP (1) JP4596913B2 (no)
KR (1) KR20050067384A (no)
CN (1) CN100480255C (no)
AT (1) ATE368048T1 (no)
AU (1) AU2003263846B2 (no)
CA (1) CA2495370A1 (no)
DE (1) DE60315164T2 (no)
ES (1) ES2288632T3 (no)
MX (1) MXPA05001844A (no)
NO (1) NO20051296L (no)
NZ (1) NZ538590A (no)
RU (1) RU2340623C2 (no)
WO (1) WO2004016635A2 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2528385C (en) 2003-06-06 2011-03-15 Endacea, Inc. A1 adenosine receptor antogonists
ES2537959T3 (es) * 2007-05-17 2015-06-16 Gilead Sciences, Inc. Proceso para preparar un agonista de receptor de adenosin-A2A y sus polimorfos
WO2013062943A1 (en) * 2011-10-24 2013-05-02 Glaxosmithkline Intellectual Property Development Limited New compounds
SG11201706050WA (en) * 2015-02-24 2017-09-28 Pfizer Substituted nucleoside derivatives useful as anticancer agents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1254888A (en) * 1984-10-26 1989-05-30 Bharat Trivedi N.sup.6-bicycloadenosines
USRE36494E (en) * 1990-02-20 2000-01-11 Discovery Therapeutics, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
US5140015A (en) * 1990-02-20 1992-08-18 Whitby Research, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
US5278150A (en) * 1992-04-24 1994-01-11 Whitby Research, Inc. 2-hydrazoadenosines and their utility for the treatmeat of vascular conditions
US5589467A (en) * 1993-09-17 1996-12-31 Novo Nordisk A/S 2,5',N6-trisubstituted adenosine derivatives
WO1997033591A1 (en) * 1996-03-13 1997-09-18 Novo Nordisk A/S A method of treating disorders related to cytokines in mammals
WO1998016539A1 (en) * 1996-10-14 1998-04-23 Novo Nordisk A/S Novel therapeutically active adenosine derivatives
GB9723589D0 (en) * 1997-11-08 1998-01-07 Glaxo Group Ltd Chemical compounds
GB9813554D0 (en) 1998-06-23 1998-08-19 Glaxo Group Ltd Chemical compounds
US20040162422A1 (en) * 2001-03-20 2004-08-19 Adrian Hall Chemical compounds

Also Published As

Publication number Publication date
JP4596913B2 (ja) 2010-12-15
WO2004016635A2 (en) 2004-02-26
CN100480255C (zh) 2009-04-22
ES2288632T3 (es) 2008-01-16
KR20050067384A (ko) 2005-07-01
JP2006505525A (ja) 2006-02-16
AU2003263846A1 (en) 2004-03-03
DE60315164T2 (de) 2008-04-30
CN1675235A (zh) 2005-09-28
MXPA05001844A (es) 2005-04-19
RU2340623C2 (ru) 2008-12-10
EP1537133B1 (en) 2007-07-25
EP1537133A2 (en) 2005-06-08
RU2005106997A (ru) 2005-11-10
US7022681B2 (en) 2006-04-04
US20060135467A1 (en) 2006-06-22
AU2003263846B2 (en) 2009-12-17
WO2004016635A3 (en) 2004-04-08
US20040043960A1 (en) 2004-03-04
CA2495370A1 (en) 2004-02-26
NZ538590A (en) 2006-10-27
DE60315164D1 (de) 2007-09-06
ATE368048T1 (de) 2007-08-15

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