NO20034278L - Sammensetninger og fremgangsmåter til behandling av HCV- infeksjoner - Google Patents

Sammensetninger og fremgangsmåter til behandling av HCV- infeksjoner

Info

Publication number
NO20034278L
NO20034278L NO20034278A NO20034278A NO20034278L NO 20034278 L NO20034278 L NO 20034278L NO 20034278 A NO20034278 A NO 20034278A NO 20034278 A NO20034278 A NO 20034278A NO 20034278 L NO20034278 L NO 20034278L
Authority
NO
Norway
Prior art keywords
methods
compositions
hcv
treating hcv
hcv infections
Prior art date
Application number
NO20034278A
Other languages
English (en)
Other versions
NO20034278D0 (no
Inventor
Ann Kwong
Randal Byrn
Lola M Reid
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of NO20034278D0 publication Critical patent/NO20034278D0/no
Publication of NO20034278L publication Critical patent/NO20034278L/no

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0031—Serum-free culture media
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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    • C12N2500/00—Specific components of cell culture medium
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/12—Hepatocyte growth factor [HGF]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/18—Liver cell growth factor (LCGF, Gly-His-Lys)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/335—Glucagon; Glucagon-like peptide [GLP]; Exendin
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/375—Thyroid stimulating hormone [TSH]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
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    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Semiconductor Lasers (AREA)
NO20034278A 2001-03-27 2003-09-25 Sammensetninger og fremgangsmåter til behandling av HCV- infeksjoner NO20034278L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27917401P 2001-03-27 2001-03-27
PCT/US2002/009685 WO2002077206A1 (en) 2001-03-27 2002-03-27 Compositiona and methods useful for hcv infection

Publications (2)

Publication Number Publication Date
NO20034278D0 NO20034278D0 (no) 2003-09-25
NO20034278L true NO20034278L (no) 2003-11-25

Family

ID=23067944

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20034278A NO20034278L (no) 2001-03-27 2003-09-25 Sammensetninger og fremgangsmåter til behandling av HCV- infeksjoner

Country Status (15)

Country Link
US (3) US7879606B2 (no)
EP (1) EP1381673B1 (no)
JP (2) JP4499990B2 (no)
KR (1) KR100947911B1 (no)
CN (1) CN100362095C (no)
AT (1) ATE431396T1 (no)
CA (1) CA2441688C (no)
DE (1) DE60232322D1 (no)
ES (1) ES2328466T3 (no)
HK (1) HK1063334A1 (no)
MX (1) MXPA03008882A (no)
NO (1) NO20034278L (no)
NZ (1) NZ528462A (no)
WO (1) WO2002077206A1 (no)
ZA (1) ZA200307373B (no)

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ZA979327B (en) 1996-10-18 1998-05-11 Vertex Pharma Inhibitors of serine proteases, particularly hepatitis C virus NS3 protease.
SV2003000617A (es) 2000-08-31 2003-01-13 Lilly Co Eli Inhibidores de la proteasa peptidomimetica ref. x-14912m
JP2006508662A (ja) 2002-12-04 2006-03-16 アプレラ コーポレイション ポリヌクレオチドの多重増幅
TWI359147B (en) 2003-09-05 2012-03-01 Vertex Pharma Inhibitors of serine proteases, particularly hcv n
EP1689857A1 (en) * 2003-12-01 2006-08-16 Vertex Pharmaceuticals Incorporated Compositions comprising fetal liver cells and methods useful for hcv infection
US8399615B2 (en) 2005-08-19 2013-03-19 Vertex Pharmaceuticals Incorporated Processes and intermediates
US7964624B1 (en) 2005-08-26 2011-06-21 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases
AR055395A1 (es) 2005-08-26 2007-08-22 Vertex Pharma Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
CA2643688A1 (en) 2006-02-27 2007-08-30 Vertex Pharmaceuticals Incorporated Co-crystals and pharmaceutical compositions comprising the same
KR20080112303A (ko) 2006-03-16 2008-12-24 버텍스 파마슈티칼스 인코포레이티드 중수소화 ｃ형 간염 프로테아제 억제제
CA2679426A1 (en) 2007-02-27 2008-09-04 Luc Farmer Inhibitors of serine proteases
KR20090115970A (ko) 2007-02-27 2009-11-10 버텍스 파마슈티칼스 인코포레이티드 공-결정 및 그를 포함하는 제약 조성물
JP5443360B2 (ja) 2007-08-30 2014-03-19 バーテックス ファーマシューティカルズ インコーポレイテッド 共結晶体およびそれを含む医薬組成物
CA2707841C (en) * 2007-12-04 2017-10-24 Prionics Ag Kit and method for detecting bovine viral diarrhea virus in tissue samples
CN101906487A (zh) * 2010-08-05 2010-12-08 中国兽医药品监察所 一种猪瘟病毒核酸标准物质的制备方法
CN104755606B (zh) * 2012-08-31 2019-04-12 阿尔伯达大学董事会 用于产生具有原代人肝细胞表型的细胞的方法和组合物
EP3289074B1 (en) 2015-04-28 2023-10-04 Université de Strasbourg Clinical gene signature-based human cell culture model and uses thereof

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US5849686A (en) 1991-03-11 1998-12-15 Creative Biomolecules, Inc. Morphogen-induced liver regeneration
US6069005A (en) 1991-08-07 2000-05-30 Albert Einstein College Of Medicine Of Yeshwa University Hapatoblasts and method of isolating same
JPH07501206A (ja) 1991-08-07 1995-02-09 イェシバ・ユニバーシティ 前駆肝細胞の増殖
ES2260759T3 (es) 1993-11-19 2006-11-01 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University Hepatoblastos y metodo de aislamiento de los mismos.
KR19990036028A (ko) * 1995-08-01 1999-05-25 다니엘 케르니 일본뇌염 백신의 공업적인 생산방법 및 이에 의한 백신
US6127116A (en) 1995-08-29 2000-10-03 Washington University Functional DNA clone for hepatitis C virus (HCV) and uses thereof
ATE550429T1 (de) * 1996-11-20 2012-04-15 Crucell Holland Bv Adenovirus-zusammensetzungen erhältlich durch ein verbessertes produktions- und reinigungsverfahren
US6133030A (en) * 1997-05-14 2000-10-17 The General Hospital Corporation Co-cultivation of cells in a micropatterned configuration
FR2775983B1 (fr) * 1998-03-13 2000-11-10 Pasteur Merieux Serums Vacc Milieu et procede de propagation et de multiplication virales
EP0972828A1 (en) * 1998-06-24 2000-01-19 Institut National De La Sante Et De La Recherche Medicale (Inserm) Process for the in vitro replication of HCV
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KR100887623B1 (ko) 2000-10-03 2009-03-11 유니버시티 오브 노스 캐롤라이나 간 전구세포의 클론 증식방법
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Also Published As

Publication number Publication date
KR100947911B1 (ko) 2010-03-17
JP4499990B2 (ja) 2010-07-14
US20110229874A1 (en) 2011-09-22
EP1381673A1 (en) 2004-01-21
CA2441688C (en) 2014-01-21
US8211696B2 (en) 2012-07-03
US20130071834A1 (en) 2013-03-21
ZA200307373B (en) 2005-06-29
WO2002077206A1 (en) 2002-10-03
ATE431396T1 (de) 2009-05-15
DE60232322D1 (de) 2009-06-25
CA2441688A1 (en) 2002-10-03
EP1381673A4 (en) 2004-11-10
CN1511190A (zh) 2004-07-07
JP2004529637A (ja) 2004-09-30
US20020142449A1 (en) 2002-10-03
NZ528462A (en) 2005-11-25
CN100362095C (zh) 2008-01-16
MXPA03008882A (es) 2003-12-08
KR20040012739A (ko) 2004-02-11
ES2328466T3 (es) 2009-11-13
JP2010142249A (ja) 2010-07-01
HK1063334A1 (en) 2004-12-24
US7879606B2 (en) 2011-02-01
EP1381673B1 (en) 2009-05-13
NO20034278D0 (no) 2003-09-25
WO2002077206A9 (en) 2004-02-19

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