NO20022650L - 4-Pyridyl-N-acyl-L-fenylalaniner - Google Patents
4-Pyridyl-N-acyl-L-fenylalaninerInfo
- Publication number
- NO20022650L NO20022650L NO20022650A NO20022650A NO20022650L NO 20022650 L NO20022650 L NO 20022650L NO 20022650 A NO20022650 A NO 20022650A NO 20022650 A NO20022650 A NO 20022650A NO 20022650 L NO20022650 L NO 20022650L
- Authority
- NO
- Norway
- Prior art keywords
- phenylalanine
- pyridyl
- acyl
- Prior art date
Links
- 229960005190 phenylalanine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16909099P | 1999-12-06 | 1999-12-06 | |
| PCT/EP2000/011979 WO2001042215A1 (en) | 1999-12-06 | 2000-11-29 | 4-pyridinyl-n-acyl-l-phenylalanines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20022650L true NO20022650L (no) | 2002-06-05 |
| NO20022650D0 NO20022650D0 (no) | 2002-06-05 |
| NO322910B1 NO322910B1 (no) | 2006-12-18 |
Family
ID=22614226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20022650A NO322910B1 (no) | 1999-12-06 | 2002-06-05 | 4-Pyridyl-N-acyl-L-fenylalaniner, anvendelse av disse som medikamenter, farmasoytiske preparater inneholdende slike forbindelser og fremgangsmate for fremstilling av disse. |
Country Status (33)
| Country | Link |
|---|---|
| EP (1) | EP1244625B1 (no) |
| JP (2) | JP2003516392A (no) |
| KR (1) | KR100492111B1 (no) |
| CN (1) | CN1196682C (no) |
| AR (1) | AR031083A1 (no) |
| AT (1) | ATE297895T1 (no) |
| AU (1) | AU779063B2 (no) |
| BR (1) | BR0016172A (no) |
| CA (1) | CA2392566A1 (no) |
| CO (1) | CO5080771A1 (no) |
| CZ (1) | CZ20022352A3 (no) |
| DE (1) | DE60020883T2 (no) |
| DK (1) | DK1244625T3 (no) |
| ES (1) | ES2243335T3 (no) |
| GC (1) | GC0000214A (no) |
| HR (1) | HRP20020467A2 (no) |
| HU (1) | HUP0203735A3 (no) |
| IL (2) | IL149622A0 (no) |
| JO (1) | JO2281B1 (no) |
| MA (1) | MA26849A1 (no) |
| MX (1) | MXPA02005240A (no) |
| MY (1) | MY128003A (no) |
| NO (1) | NO322910B1 (no) |
| NZ (1) | NZ518888A (no) |
| PE (1) | PE20010960A1 (no) |
| PL (1) | PL364814A1 (no) |
| PT (1) | PT1244625E (no) |
| RU (1) | RU2270193C2 (no) |
| TW (1) | TWI276629B (no) |
| UY (1) | UY26470A1 (no) |
| WO (1) | WO2001042215A1 (no) |
| YU (1) | YU40502A (no) |
| ZA (1) | ZA200203762B (no) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6960597B2 (en) | 2000-06-30 | 2005-11-01 | Orth-Mcneil Pharmaceutical, Inc. | Aza-bridged-bicyclic amino acid derivatives as α4 integrin antagonists |
| CA2420040C (en) | 2000-08-18 | 2009-02-03 | Ajinomoto Co., Inc. | New phenylalanine derivatives |
| JP4895067B2 (ja) | 2000-09-29 | 2012-03-14 | 味の素株式会社 | 新規フェニルアラニン誘導体 |
| WO2003053926A1 (en) | 2001-12-13 | 2003-07-03 | Ajinomoto Co.,Inc. | Novel phenylalanine derivative |
| US7482366B2 (en) | 2001-12-21 | 2009-01-27 | X-Ceptor Therapeutics, Inc. | Modulators of LXR |
| US7998986B2 (en) | 2001-12-21 | 2011-08-16 | Exelixis Patent Company Llc | Modulators of LXR |
| BRPI0418026A (pt) | 2003-12-22 | 2007-04-17 | Ajinomoto Kk | derivados de fenilalanina ou sais farmaceuticamente aceitáveis destes, composição farmacêutica, antagonista de alfa4 integrina, e, agente terapêutico ou agente preventivo para doenças |
| US7618981B2 (en) * | 2004-05-06 | 2009-11-17 | Cytokinetics, Inc. | Imidazopyridinyl-benzamide anti-cancer agents |
| WO2006023396A2 (en) * | 2004-08-16 | 2006-03-02 | Merck & Co., Inc. | Vla-4 antagonists |
| JP4784224B2 (ja) | 2004-09-24 | 2011-10-05 | 味の素株式会社 | 糖鎖転移方法および糖鎖転移酵素 |
| US8410115B2 (en) * | 2006-02-28 | 2013-04-02 | Elan Pharmaceuticals, Inc. | Methods of treating inflammatory and autoimmune diseases with alpha-4 inhibitory compounds |
| TW200811164A (en) * | 2006-05-12 | 2008-03-01 | Jerini Ag | New heterocyclic compounds for the inhibition of integrins and use thereof |
| AU2008219007A1 (en) | 2007-02-20 | 2008-08-28 | Merrimack Pharmaceuticals, Inc. | Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist |
| JP5639039B2 (ja) | 2008-04-11 | 2014-12-10 | メリマック ファーマシューティカルズ インコーポレーティッド | ヒト血清アルブミンリンカーおよびそのコンジュゲート |
| RU2012106074A (ru) * | 2009-07-23 | 2013-08-27 | Байер Кропсайенс Аг | Новые алкоксиеноны и енаминокетоны и способ их получения |
| US8877815B2 (en) | 2010-11-16 | 2014-11-04 | Novartis Ag | Substituted carbamoylcycloalkyl acetic acid derivatives as NEP |
| BR112014013135A2 (pt) * | 2012-01-27 | 2017-12-05 | Hoffmann La Roche | composto, composição farmacêutica, método para o tratamento da inflamação, uso de um composto e invenção |
| JP6573604B2 (ja) * | 2013-06-11 | 2019-09-11 | セルジーン インターナショナル ツー エスエーアールエル | 新規なｇｌｐ−１レセプターモジュレーター |
| ES2856125T3 (es) | 2016-02-05 | 2021-09-27 | Ea Pharma Co Ltd | Derivado de sulfonamida y composición farmacéutica que contiene la misma |
| DK3873884T3 (da) | 2018-10-30 | 2025-02-17 | Gilead Sciences Inc | 3-(quinolin-8-yl)-1,4-dihydropyrido[3,4-d]pyrimidin-2,4-dion-derivater som alpha4beta7-integrinhæmmere til behandling af inflammatoriske sygdomme |
| WO2020092394A1 (en) | 2018-10-30 | 2020-05-07 | Gilead Sciences, Inc. | Imidazopyridine derivatives as alpha4beta7 integrin inhibitors |
| WO2020092401A1 (en) | 2018-10-30 | 2020-05-07 | Gilead Sciences, Inc. | COMPOUNDS FOR INHIBITION OF ALPHA 4β7 INTEGRIN |
| ES2987796T3 (es) | 2018-10-30 | 2024-11-18 | Gilead Sciences Inc | Derivados de N-benzoil-fenilalanina como inhibidores de la integrina alfa4beta7 para el tratamiento de enfermedades inflamatorias |
| AU2020329207B2 (en) | 2019-08-14 | 2024-02-29 | Gilead Sciences, Inc. | Compounds for inhibition of alpha 4 beta 7 integrin |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA848275B (en) * | 1983-12-28 | 1985-08-28 | Degussa | New piridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring |
| EP1001764A4 (en) * | 1997-05-29 | 2005-08-24 | Merck & Co Inc | HETEROCYCLIC AMIDE COMPOUNDS AS INHIBITORS OF CELL ADHESION |
| ATE318841T1 (de) * | 1997-05-29 | 2006-03-15 | Merck & Co Inc | Biarylalkansäuren in der verwendung als zelladhäsionsinhibitoren |
| US6197794B1 (en) * | 1998-01-08 | 2001-03-06 | Celltech Therapeutics Limited | Phenylalanine derivatives |
| MY153569A (en) * | 1998-01-20 | 2015-02-27 | Mitsubishi Tanabe Pharma Corp | Inhibitors of ?4 mediated cell adhesion |
| US6329372B1 (en) * | 1998-01-27 | 2001-12-11 | Celltech Therapeutics Limited | Phenylalanine derivatives |
| JP2002504534A (ja) * | 1998-02-26 | 2002-02-12 | セルテック・セラピューティクス・リミテッド | α４インテグリンの阻害剤としてのフェニルアラニン誘導体 |
| GB9811159D0 (en) * | 1998-05-22 | 1998-07-22 | Celltech Therapeutics Ltd | Chemical compounds |
| JP2003524614A (ja) * | 1998-12-22 | 2003-08-19 | 田辺製薬株式会社 | α４β１媒介細胞接着のインヒビター |
| AR035838A1 (es) * | 1999-01-22 | 2004-07-21 | Elan Pharm Inc | Compuestos multiciclicos que inhiben la adhesion de leucocitos mediada por vla-4 y el uso de los mismos para la preparacion de un medicamento |
-
2000
- 2000-11-29 DK DK00985117T patent/DK1244625T3/da active
- 2000-11-29 WO PCT/EP2000/011979 patent/WO2001042215A1/en not_active Ceased
- 2000-11-29 JP JP2001543516A patent/JP2003516392A/ja active Pending
- 2000-11-29 PT PT00985117T patent/PT1244625E/pt unknown
- 2000-11-29 CA CA002392566A patent/CA2392566A1/en not_active Abandoned
- 2000-11-29 RU RU2002117419/04A patent/RU2270193C2/ru not_active IP Right Cessation
- 2000-11-29 PL PL00364814A patent/PL364814A1/xx not_active Application Discontinuation
- 2000-11-29 ES ES00985117T patent/ES2243335T3/es not_active Expired - Lifetime
- 2000-11-29 MX MXPA02005240A patent/MXPA02005240A/es active IP Right Grant
- 2000-11-29 CZ CZ20022352A patent/CZ20022352A3/cs unknown
- 2000-11-29 BR BR0016172-1A patent/BR0016172A/pt not_active Application Discontinuation
- 2000-11-29 JO JO2000189A patent/JO2281B1/en active
- 2000-11-29 YU YU40502A patent/YU40502A/sh unknown
- 2000-11-29 DE DE60020883T patent/DE60020883T2/de not_active Expired - Lifetime
- 2000-11-29 HU HU0203735A patent/HUP0203735A3/hu unknown
- 2000-11-29 CN CNB008164800A patent/CN1196682C/zh not_active Expired - Fee Related
- 2000-11-29 HR HR20020467A patent/HRP20020467A2/xx not_active Application Discontinuation
- 2000-11-29 IL IL14962200A patent/IL149622A0/xx active IP Right Grant
- 2000-11-29 AT AT00985117T patent/ATE297895T1/de not_active IP Right Cessation
- 2000-11-29 AU AU21639/01A patent/AU779063B2/en not_active Ceased
- 2000-11-29 NZ NZ518888A patent/NZ518888A/en unknown
- 2000-11-29 EP EP00985117A patent/EP1244625B1/en not_active Expired - Lifetime
- 2000-11-29 KR KR10-2002-7007201A patent/KR100492111B1/ko not_active Expired - Fee Related
- 2000-12-02 GC GCP20001072 patent/GC0000214A/en active
- 2000-12-04 MY MYPI20005689A patent/MY128003A/en unknown
- 2000-12-04 AR ARP000106416A patent/AR031083A1/es not_active Application Discontinuation
- 2000-12-05 TW TW089125889A patent/TWI276629B/zh not_active IP Right Cessation
- 2000-12-05 CO CO00092690A patent/CO5080771A1/es unknown
- 2000-12-05 UY UY26470A patent/UY26470A1/es not_active Application Discontinuation
- 2000-12-06 PE PE2000001306A patent/PE20010960A1/es not_active Application Discontinuation
-
2002
- 2002-05-10 ZA ZA200203762A patent/ZA200203762B/xx unknown
- 2002-05-13 IL IL149622A patent/IL149622A/en not_active IP Right Cessation
- 2002-06-05 MA MA26672A patent/MA26849A1/fr unknown
- 2002-06-05 NO NO20022650A patent/NO322910B1/no unknown
-
2007
- 2007-10-05 JP JP2007262543A patent/JP2008094842A/ja active Pending
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