NO20021701D0 - Fremgangsmåte for fremstilling av et konjugat av polyglutamat og et terapeutisk middel - Google Patents
Fremgangsmåte for fremstilling av et konjugat av polyglutamat og et terapeutisk middelInfo
- Publication number
- NO20021701D0 NO20021701D0 NO20021701A NO20021701A NO20021701D0 NO 20021701 D0 NO20021701 D0 NO 20021701D0 NO 20021701 A NO20021701 A NO 20021701A NO 20021701 A NO20021701 A NO 20021701A NO 20021701 D0 NO20021701 D0 NO 20021701D0
- Authority
- NO
- Norway
- Prior art keywords
- polyglutamate
- conjugate
- preparation
- therapeutic agent
- therapeutic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
- Polyamides (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15913599P | 1999-10-12 | 1999-10-12 | |
| PCT/US2000/028109 WO2001026693A2 (en) | 1999-10-12 | 2000-10-12 | Manufacture of polyglutamate-therapeutic agent conjugates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20021701D0 true NO20021701D0 (no) | 2002-04-11 |
| NO20021701L NO20021701L (no) | 2002-05-23 |
Family
ID=22571222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20021701A NO20021701L (no) | 1999-10-12 | 2002-04-11 | Fremgangsmåte for fremstilling av et konjugat av polyglutamat og et terapeutisk middel |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20020077279A1 (no) |
| EP (2) | EP1466627A1 (no) |
| JP (1) | JP2003511423A (no) |
| KR (1) | KR100821437B1 (no) |
| CN (2) | CN101507820A (no) |
| AU (1) | AU781735B2 (no) |
| BR (1) | BRPI0014652B1 (no) |
| CA (1) | CA2387611C (no) |
| HU (1) | HUP0203123A3 (no) |
| MX (1) | MXPA02003719A (no) |
| NO (1) | NO20021701L (no) |
| NZ (1) | NZ529789A (no) |
| PL (1) | PL354623A1 (no) |
| SG (1) | SG147286A1 (no) |
| WO (1) | WO2001026693A2 (no) |
| ZA (1) | ZA200202695B (no) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2413149A1 (en) | 2000-06-14 | 2001-12-20 | Medarex, Inc. | Prodrug compounds with isoleucine |
| US6872715B2 (en) | 2001-08-06 | 2005-03-29 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
| US8709998B2 (en) | 2003-04-22 | 2014-04-29 | Ipsen Pharma S.A.S. | Peptide vectors |
| FR2855521B1 (fr) * | 2003-05-28 | 2005-08-05 | Flamel Tech Sa | Polyaminoacides fonctionnalises par au moins un groupement h ydrophobe et leurs applications notamment therapeutiques. |
| US7259156B2 (en) | 2004-05-20 | 2007-08-21 | Kosan Biosciences Incorporated | Geldanamycin compounds and method of use |
| US8614228B2 (en) | 2004-08-11 | 2013-12-24 | Arqule, Inc. | Quinone prodrug compositions and methods of use |
| CA2583700A1 (en) | 2004-08-11 | 2006-02-23 | Arqule, Inc. | Quinone prodrug compositions and methods of use |
| KR101203475B1 (ko) | 2004-09-22 | 2012-11-21 | 니폰 가야꾸 가부시끼가이샤 | 신규 블록 공중합체, 미셀 제제물 및 이를 유효성분으로함유하는 항암제 |
| ATE432955T1 (de) | 2005-12-05 | 2009-06-15 | Nitto Denko Corp | Polyglutamat-aminosäure-konjugate und verfahren |
| US20070167349A1 (en) * | 2005-12-06 | 2007-07-19 | Cell Therapeutics, Inc. | Estrogen cancer therapy |
| US7462627B2 (en) * | 2006-02-09 | 2008-12-09 | Enzon Pharmaceuticals, Inc. | Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers |
| US7671067B2 (en) * | 2006-02-09 | 2010-03-02 | Enzon Pharmaceuticals, Inc. | Treatment of non-hodgkin's lymphomas with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamtothecin |
| KR20080106254A (ko) | 2006-03-28 | 2008-12-04 | 니폰 가야꾸 가부시끼가이샤 | 탁산류의 고분자 결합체 |
| US8940332B2 (en) | 2006-05-18 | 2015-01-27 | Nippon Kayaku Kabushiki Kaisha | High-molecular weight conjugate of podophyllotoxins |
| EP2080779B1 (en) | 2006-11-06 | 2016-05-18 | Nippon Kayaku Kabushiki Kaisha | Polymeric derivative of nucleic acid metabolic antagonist |
| JP5548365B2 (ja) | 2006-11-08 | 2014-07-16 | 日本化薬株式会社 | 核酸系代謝拮抗剤の高分子誘導体 |
| CN101209350B (zh) * | 2006-12-30 | 2011-09-07 | 中国人民解放军军事医学科学院毒物药物研究所 | 以氨基酸为连接子的多聚谷氨酸-药物偶合物 |
| MX2009008549A (es) * | 2007-02-09 | 2009-08-18 | Enzon Pharmaceuticals Inc | Tratamiento de canceres resistentes o refractarios con conjugados polimericos de brazos multiples de 7-etil-10-hidroxicamptotecina. |
| CN101674852A (zh) * | 2007-04-10 | 2010-03-17 | 日东电工株式会社 | 多功能聚谷氨酸盐药物载体 |
| TWI401081B (zh) | 2007-04-30 | 2013-07-11 | Arqule Inc | 苯醌化合物的羥基磺酸鹽及其用途 |
| CN101730549B (zh) * | 2007-05-09 | 2015-12-09 | 日东电工株式会社 | 与铂类药物结合的聚合物 |
| JP2010526917A (ja) * | 2007-05-09 | 2010-08-05 | 日東電工株式会社 | 複数種の薬物を有するポリグルタミン酸塩複合体及びポリグルタミン酸塩−アミノ酸複合体 |
| ES2430380T3 (es) * | 2007-05-09 | 2013-11-20 | Nitto Denko Corporation | Composiciones que incluyen un compuesto hidrófobo y un conjugado de poliaminoácido |
| JP5349318B2 (ja) | 2007-09-28 | 2013-11-20 | 日本化薬株式会社 | ステロイド類の高分子結合体 |
| CA2716662A1 (en) * | 2008-03-06 | 2009-03-11 | Nitto Denko Corporation | Polymer paclitaxel conjugates and methods for treating cancer |
| EP2258397B1 (en) | 2008-03-18 | 2017-10-11 | Nippon Kayaku Kabushiki Kaisha | Polymer conjugate of physiologically active substance |
| WO2009136572A1 (ja) | 2008-05-08 | 2009-11-12 | 日本化薬株式会社 | 葉酸若しくは葉酸誘導体の高分子結合体 |
| US20100056555A1 (en) * | 2008-08-29 | 2010-03-04 | Enzon Pharmaceuticals, Inc. | Method of treating ras associated cancer |
| BRPI0920655A2 (pt) | 2008-10-07 | 2019-07-09 | Rexahn Pharmaceuticals Inc | conjugados e hpma-docetaxel ou gencitabina e usos dos mesmos |
| EP2358396A2 (en) * | 2008-10-15 | 2011-08-24 | Nitto Denko Corporation | Method of preparing polyglutamate conjugates |
| CN102215688A (zh) * | 2008-10-21 | 2011-10-12 | 安龙制药公司 | 用7-乙基-10-羟基喜树碱的多臂聚合物对神经母细胞瘤的治疗 |
| DE102008060549A1 (de) * | 2008-12-04 | 2010-06-10 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung |
| CN102421827B (zh) | 2009-05-15 | 2014-07-30 | 日本化药株式会社 | 具有羟基的生理活性物质的高分子结合体 |
| AU2010306917B2 (en) | 2009-10-13 | 2014-11-27 | Rexahn Pharmaceuticals, Inc. | Polymeric systems for the delivery of anticancer agents |
| AU2011224374A1 (en) * | 2010-03-11 | 2012-09-27 | Nitto Denko Corporation | Carbohydrate-polyamino acid-drug conjugates |
| WO2011123813A2 (en) | 2010-04-02 | 2011-10-06 | Amunix Operating Inc. | Binding fusion proteins, binding fusion protein-drug conjugates, xten-drug conjugates and methods of making and using same |
| EP2641605B1 (en) | 2010-11-17 | 2018-03-07 | Nippon Kayaku Kabushiki Kaisha | Polymer derivative of cytidine metabolism antagonist |
| CN102649810A (zh) * | 2011-05-19 | 2012-08-29 | 东北林业大学 | 喜树碱衍生物、其制备方法和用途 |
| US8691284B2 (en) | 2011-07-07 | 2014-04-08 | Empire Technology Development Llc | Fluorinated block co-polymers |
| EP2754682B1 (en) | 2011-09-11 | 2017-06-07 | Nippon Kayaku Kabushiki Kaisha | Method for manufacturing block copolymer |
| US8383093B1 (en) | 2011-11-01 | 2013-02-26 | Serina Therapeutics, Inc. | Subcutaneous delivery of poly(oxazoline) conjugates |
| US8907045B2 (en) | 2012-04-03 | 2014-12-09 | Empire Technology Development Llc | Biocompatible adhesive polymers |
| US9839694B2 (en) | 2013-04-26 | 2017-12-12 | Nitto Denko Corporation | Reduction of endotoxins from polyanionic polymer conjugates |
| KR101507119B1 (ko) * | 2013-05-31 | 2015-03-30 | 주식회사 바이오리더스 | 점막 점착성 폴리감마글루탐산 나노마이셀 및 이를 이용한 약물 전달체 |
| CN106267227A (zh) * | 2016-08-12 | 2017-01-04 | 北京蓝贝望生物医药科技股份有限公司 | 抗肿瘤药物 |
| CN106750272B (zh) * | 2016-12-05 | 2019-05-28 | 福建卫生职业技术学院 | 一种水溶性蛇葡萄素聚合物 |
| CN110123748A (zh) * | 2019-04-22 | 2019-08-16 | 南京师范大学 | 一种叶酸介导的靶向双载药聚合物胶束及其制备方法和应用 |
| CN113773282A (zh) * | 2021-09-22 | 2021-12-10 | 无锡紫杉药业有限公司 | 一种10-乙酰紫杉醇的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4356166A (en) * | 1978-12-08 | 1982-10-26 | University Of Utah | Time-release chemical delivery system |
| US5629433A (en) * | 1994-07-18 | 1997-05-13 | Hauser, Inc. | Selective process for the deacylation and deacetylation of taxol and taxanes |
| CA2192725C (en) * | 1995-12-28 | 2004-04-20 | Kenji Tsujihara | Camptothecin derivatives |
| AU735900B2 (en) * | 1996-03-12 | 2001-07-19 | Pg-Txl Company, L.P. | Water soluble paclitaxel prodrugs |
| US6441025B2 (en) * | 1996-03-12 | 2002-08-27 | Pg-Txl Company, L.P. | Water soluble paclitaxel derivatives |
| IL151685A0 (en) * | 2000-03-17 | 2003-04-10 | Cell Therapeutics Inc | Polyglutamic acid-camptothecin conjugates, methods for the preparation thereof and pharmaceutical compositons containing the same |
-
2000
- 2000-10-12 AU AU10793/01A patent/AU781735B2/en not_active Ceased
- 2000-10-12 EP EP04013703A patent/EP1466627A1/en not_active Withdrawn
- 2000-10-12 SG SG200401981-6A patent/SG147286A1/en unknown
- 2000-10-12 EP EP00972079A patent/EP1225917A2/en not_active Withdrawn
- 2000-10-12 HU HU0203123A patent/HUP0203123A3/hu unknown
- 2000-10-12 PL PL00354623A patent/PL354623A1/xx not_active IP Right Cessation
- 2000-10-12 KR KR1020027004640A patent/KR100821437B1/ko not_active IP Right Cessation
- 2000-10-12 CA CA2387611A patent/CA2387611C/en not_active Expired - Fee Related
- 2000-10-12 JP JP2001529754A patent/JP2003511423A/ja active Pending
- 2000-10-12 WO PCT/US2000/028109 patent/WO2001026693A2/en active IP Right Grant
- 2000-10-12 MX MXPA02003719A patent/MXPA02003719A/es active IP Right Grant
- 2000-10-12 CN CNA2009101276554A patent/CN101507820A/zh active Pending
- 2000-10-12 BR BRPI0014652A patent/BRPI0014652B1/pt not_active IP Right Cessation
- 2000-10-12 CN CNA008170290A patent/CN1607962A/zh active Pending
- 2000-10-12 NZ NZ529789A patent/NZ529789A/en not_active IP Right Cessation
-
2001
- 2001-10-09 US US09/971,657 patent/US20020077279A1/en not_active Abandoned
-
2002
- 2002-04-05 ZA ZA200202695A patent/ZA200202695B/en unknown
- 2002-04-11 NO NO20021701A patent/NO20021701L/no not_active Application Discontinuation
-
2003
- 2003-04-02 US US10/404,152 patent/US7399860B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200202695B (en) | 2004-02-25 |
| US20020077279A1 (en) | 2002-06-20 |
| WO2001026693A2 (en) | 2001-04-19 |
| CA2387611C (en) | 2011-03-29 |
| SG147286A1 (en) | 2008-11-28 |
| US20030224971A1 (en) | 2003-12-04 |
| EP1225917A2 (en) | 2002-07-31 |
| CA2387611A1 (en) | 2001-04-19 |
| JP2003511423A (ja) | 2003-03-25 |
| BRPI0014652B1 (pt) | 2016-08-09 |
| AU1079301A (en) | 2001-04-23 |
| HUP0203123A2 (hu) | 2003-01-28 |
| PL354623A1 (en) | 2004-02-09 |
| CN1607962A (zh) | 2005-04-20 |
| BR0014652A (pt) | 2003-06-10 |
| KR20020059616A (ko) | 2002-07-13 |
| WO2001026693A3 (en) | 2001-12-27 |
| NZ529789A (en) | 2005-04-29 |
| EP1466627A1 (en) | 2004-10-13 |
| KR100821437B1 (ko) | 2008-04-10 |
| HUP0203123A3 (en) | 2004-12-28 |
| CN101507820A (zh) | 2009-08-19 |
| US7399860B2 (en) | 2008-07-15 |
| MXPA02003719A (es) | 2002-08-30 |
| NO20021701L (no) | 2002-05-23 |
| AU781735B2 (en) | 2005-06-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |