NO20020938L - Substituerte alfa-hydroksysyre-caspaseinhibitorer og deres anvendelse - Google Patents
Substituerte alfa-hydroksysyre-caspaseinhibitorer og deres anvendelseInfo
- Publication number
- NO20020938L NO20020938L NO20020938A NO20020938A NO20020938L NO 20020938 L NO20020938 L NO 20020938L NO 20020938 A NO20020938 A NO 20020938A NO 20020938 A NO20020938 A NO 20020938A NO 20020938 L NO20020938 L NO 20020938L
- Authority
- NO
- Norway
- Prior art keywords
- hydroxy acid
- substituted alpha
- caspase inhibitors
- inhibitors
- cell death
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
- C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15107799P | 1999-08-27 | 1999-08-27 | |
US15837399P | 1999-10-12 | 1999-10-12 | |
PCT/US2000/023566 WO2001016093A1 (en) | 1999-08-27 | 2000-08-28 | SUBSTITUTED α-HYDROXY ACID CASPASE INHIBITORS AND THE USE THEREOF |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20020938D0 NO20020938D0 (no) | 2002-02-26 |
NO20020938L true NO20020938L (no) | 2002-04-15 |
Family
ID=26848309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20020938A NO20020938L (no) | 1999-08-27 | 2002-02-26 | Substituerte alfa-hydroksysyre-caspaseinhibitorer og deres anvendelse |
Country Status (15)
Country | Link |
---|---|
US (1) | US6495522B1 (de) |
EP (1) | EP1212295B1 (de) |
JP (1) | JP2003508379A (de) |
KR (1) | KR20020033777A (de) |
CN (1) | CN1235875C (de) |
AT (1) | ATE409688T1 (de) |
AU (1) | AU775291B2 (de) |
BR (1) | BR0013666A (de) |
CA (1) | CA2383002A1 (de) |
DE (1) | DE60040397D1 (de) |
EA (1) | EA200200301A1 (de) |
IL (1) | IL148426A0 (de) |
MX (1) | MXPA02002038A (de) |
NO (1) | NO20020938L (de) |
WO (1) | WO2001016093A1 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6184210B1 (en) * | 1997-10-10 | 2001-02-06 | Cytovia, Inc. | Dipeptide apoptosis inhibitors and the use thereof |
US6248904B1 (en) * | 1998-07-21 | 2001-06-19 | Cytovia, Inc. | Fluorescence dyes and their applications for whole-cell fluorescence screening assays for caspases, peptidases, proteases and other enzymes and the use thereof |
CN1346344A (zh) * | 1999-03-16 | 2002-04-24 | 西托维亚公司 | 取代的2-氨基苯甲酰胺天冬氨酸特异性半胱氨酸蛋白酶抑制剂及其应用 |
JP2002541237A (ja) * | 1999-04-09 | 2002-12-03 | サイトビア インコーポレイテッド | カスパーゼインヒビターおよびその使用 |
AU2001249619B2 (en) | 2000-03-29 | 2006-08-17 | Vertex Pharmaceuticals Incorporated | Carbamate caspase inhibitors and uses thereof |
PE20011350A1 (es) | 2000-05-19 | 2002-01-15 | Vertex Pharma | PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE) |
WO2002079459A2 (en) * | 2001-03-29 | 2002-10-10 | Nsgene A/S | Means for inhibiting proteolytical processing of parkin |
US6777443B2 (en) * | 2001-05-15 | 2004-08-17 | Novartis Ag | Dipeptide derivatives |
WO2002094263A2 (en) * | 2001-05-23 | 2002-11-28 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
WO2003008373A1 (de) * | 2001-07-19 | 2003-01-30 | Merck Patent Gmbh | Tyrosinhydrazide |
WO2003068242A1 (en) | 2002-02-11 | 2003-08-21 | Vertex Pharmaceuticals Incorporated | Phospholipids as caspase inhibitor prodrugs |
US20050171023A1 (en) * | 2002-04-05 | 2005-08-04 | Cai Sui X. | Caspase inhibitors for the treatment of diseases and conditions caused by exposure to radionuclides, biological agents, or chemical agents |
WO2003088917A2 (en) * | 2002-04-19 | 2003-10-30 | Vertex Pharmaceuticals Incorporated | Regulation of tnf-alpha |
US7504382B2 (en) * | 2003-05-06 | 2009-03-17 | Cytovia, Inc. | Protease inhibitors for coronaviruses and SARS-CoV and the use thereof |
US7482379B2 (en) * | 2004-02-18 | 2009-01-27 | Georgia Tech Research Corporation | Propenoyl hydrazides |
JP4898658B2 (ja) | 2004-03-12 | 2012-03-21 | バーテックス ファーマシューティカルズ インコーポレイテッド | アスパラギン酸アセタールカスパーゼ阻害剤の製造のための方法および中間体 |
CA2566362C (en) | 2004-05-15 | 2013-09-10 | Vertex Pharmaceuticals Incorporated | Treating seizures using ice inhibitors |
CN1980658A (zh) | 2004-05-27 | 2007-06-13 | 沃泰克斯药物股份有限公司 | 治疗自身炎性疾病的ice抑制剂 |
WO2009076598A1 (en) | 2007-12-12 | 2009-06-18 | Children's Hospital & Research Center At Oakland | Use of unsaturated sphingosine compounds as chemotherapeutic agents for the treatment of cancer |
EP2352724B1 (de) * | 2008-09-11 | 2015-04-22 | The Regents of the University of Michigan | Arylguanidine-f1f0-aptase inhibitoren und deren therapeutischen verwendung |
HUP1000243A2 (en) | 2010-05-06 | 2012-01-30 | Avidin Kft | 8-hidroxy-quinoline derivatives |
WO2012061786A1 (en) | 2010-11-05 | 2012-05-10 | Brandeis University | Ice cleaved alpha-synuclein a biomarker |
US9956260B1 (en) | 2011-07-22 | 2018-05-01 | The J. David Gladstone Institutes | Treatment of HIV-1 infection and AIDS |
CA2930084A1 (en) * | 2013-11-21 | 2015-05-28 | Allergan, Inc. | Phenylcarbamate derivatives as formyl peptide receptor modulators |
CN104803864B (zh) * | 2014-01-29 | 2017-01-11 | 华东师范大学 | β-羟基-α-氨基酸衍生物及其合成方法和应用 |
GB201712282D0 (en) * | 2017-07-31 | 2017-09-13 | Nodthera Ltd | Selective inhibitors of NLRP3 inflammasome |
Family Cites Families (45)
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FR2381023A1 (fr) | 1977-02-18 | 1978-09-15 | Delalande Sa | Nouveaux oligopeptides trifluoromethyles derives de la l-alanine, leur procede de preparation et leur application en therapeutique |
US4518528A (en) | 1983-05-19 | 1985-05-21 | Rasnick David W | α Amino fluoro ketones |
US5221607A (en) | 1989-09-18 | 1993-06-22 | Scios Nova Inc. | Assays and reagents for amyloid deposition |
US5416013A (en) | 1990-04-04 | 1995-05-16 | Sterling Winthrop Inc. | Interleukin 1β protease and interleukin 1β protease inhibitors |
US5252463A (en) | 1990-06-22 | 1993-10-12 | The Du Pont Merck Pharmaceutical Company | Clipsin, a chymotrypsin-like protease and method of using same |
US5824297A (en) | 1990-06-25 | 1998-10-20 | Oncogene Science, Inc. | Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof |
EP0519748B1 (de) | 1991-06-21 | 1998-09-02 | Merck & Co. Inc. | Peptidylderivate als Inhibitoren von Interleukin-1B-konvertierenden Enzymen |
HU220098B (hu) | 1991-08-30 | 2001-10-28 | Vertex Pharmaceuticals Incorporated | Interleukin-1 béta proteáz enzim, és interleukin-1 béta proteáz inhibitorok |
DE69320176T2 (de) | 1992-02-21 | 1999-04-08 | Merck & Co Inc | Peptidylderivate und inhibitoren des interleukin-1-g(b)-konvertierenden enzyms |
EP0618223A3 (de) | 1993-03-08 | 1996-06-12 | Sandoz Ltd | Peptide, die Freisetzung vom Interleukin 1-Bêta, nützlich als entzündungshemmende Wirkstoffe. |
TW494094B (en) * | 1993-04-29 | 2002-07-11 | Vertex Pharma | Peptide analogs as irreversible interleukin-1β protease inhibitors and pharmaceutical compositions comprising the same |
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JPH0789951A (ja) | 1993-06-03 | 1995-04-04 | Sterling Winthrop Inc | インターロイキン−1β転換酵素阻害剤 |
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WO1995005192A1 (en) | 1993-08-13 | 1995-02-23 | Merck & Co., Inc. | SUBSTITUTED KETONE DERIVATIVES AS INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME |
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US5565430A (en) * | 1994-08-02 | 1996-10-15 | Sterling Winthrop Inc. | Azaaspartic acid analogs as interleukin-1β converting enzyme inhibitors |
US5744451A (en) | 1995-09-12 | 1998-04-28 | Warner-Lambert Company | N-substituted glutamic acid derivatives with interleukin-1 β converting enzyme inhibitory activity |
US5843904A (en) | 1995-12-20 | 1998-12-01 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1βconverting enzyme |
AU739496B2 (en) | 1996-09-12 | 2001-10-11 | Idun Pharmaceuticals, Incorporated | Novel tricyclic compounds for the inhibition of the ice/ced-3 protease family of enzymes |
US5869519A (en) | 1996-12-16 | 1999-02-09 | Idun Pharmaceuticals, Inc. | C-terminal modified (n-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases |
US6200969B1 (en) | 1996-09-12 | 2001-03-13 | Idun Pharmaceuticals, Inc. | Inhibition of apoptosis using interleukin-1β-converting enzyme (ICE)/CED-3 family inhibitors |
CA2265853C (en) | 1996-09-12 | 2010-08-03 | Idun Pharmaceuticals, Inc. | Inhibition of apoptosis using interleukin-1.beta.-converting enzyme (ice)/ced-3 family inhibitors |
US5877197A (en) | 1996-12-16 | 1999-03-02 | Karanewsky; Donald S. | C-terminal modified (N-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases |
US6184244B1 (en) | 1996-12-16 | 2001-02-06 | Idun Pharmaceuticals, Inc. | C-terminal modified (N-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases |
BR9810409A (pt) | 1997-03-18 | 2000-08-22 | Basf Ag | Métodos e composições para a modulação de responsividade a corticosteróides |
JPH111491A (ja) | 1997-04-18 | 1999-01-06 | Takeda Chem Ind Ltd | ペプチド類及びその剤 |
US6184210B1 (en) | 1997-10-10 | 2001-02-06 | Cytovia, Inc. | Dipeptide apoptosis inhibitors and the use thereof |
KR100580333B1 (ko) | 1997-10-10 | 2006-05-16 | 시토비아 인크. | 디펩티드 고사 억제제 및 그의 용도 |
JPH11180891A (ja) | 1997-12-25 | 1999-07-06 | Dai Ichi Seiyaku Co Ltd | 抗細胞死剤 |
CA2323439A1 (en) | 1998-03-16 | 1999-09-23 | Cytovia, Inc. | Dipeptide caspase inhibitors and the use thereof |
TR200003252T2 (tr) | 1998-05-05 | 2001-04-20 | Warner-Lambert Company | Interleukın-1ß dönüştürme enzimi succınamıde inhibitörleri. |
US6197750B1 (en) | 1998-07-02 | 2001-03-06 | Idun Pharmaceuticals, Inc. | C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases |
US6201118B1 (en) | 1998-08-19 | 2001-03-13 | Vertex Pharmaceuticals Inc. | Process for forming an N-acylated, N,N-containing bicyclic ring from piperazic acid or an ester thereof especially useful as an intermediate in the manufacture of a caspase inhibitor |
US6242422B1 (en) | 1998-10-22 | 2001-06-05 | Idun Pharmacueticals, Inc. | (Substituted)Acyl dipeptidyl inhibitors of the ice/ced-3 family of cysteine proteases |
EP1135406A1 (de) | 1998-12-02 | 2001-09-26 | Merck Frosst Canada & Co. | Gamma-ketosäure-tetrapeptide als kaspase-3-inhibitoren |
CN1346344A (zh) | 1999-03-16 | 2002-04-24 | 西托维亚公司 | 取代的2-氨基苯甲酰胺天冬氨酸特异性半胱氨酸蛋白酶抑制剂及其应用 |
EP1163214A1 (de) | 1999-03-16 | 2001-12-19 | Merck Frosst Canada & Co. | Gamma-ketosäure-dipeptide als inhibitoren von caspase-3 |
JP2002541237A (ja) | 1999-04-09 | 2002-12-03 | サイトビア インコーポレイテッド | カスパーゼインヒビターおよびその使用 |
AU6894800A (en) | 1999-08-06 | 2001-03-05 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
US6566338B1 (en) | 1999-10-12 | 2003-05-20 | Cytovia, Inc. | Caspase inhibitors for the treatment and prevention of chemotherapy and radiation therapy induced cell death |
AR026748A1 (es) | 1999-12-08 | 2003-02-26 | Vertex Pharma | Un compuesto inhibidor de caspasas, una composicion farmaceutica que lo comprende, un metodo para la sintesis del mismo y un compuesto intermediario paradicha sintesis |
AU2001249619B2 (en) | 2000-03-29 | 2006-08-17 | Vertex Pharmaceuticals Incorporated | Carbamate caspase inhibitors and uses thereof |
PE20020058A1 (es) | 2000-05-23 | 2002-01-31 | Vertex Pharma | Derivados de piperidina tetrahidroquinolina, tetrahidroisoquinolina como inhibidores de caspasas |
AU2001275279B2 (en) | 2000-06-07 | 2007-01-04 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
-
2000
- 2000-08-28 US US09/649,810 patent/US6495522B1/en not_active Expired - Fee Related
- 2000-08-28 BR BR0013666-2A patent/BR0013666A/pt not_active Application Discontinuation
- 2000-08-28 KR KR1020027002581A patent/KR20020033777A/ko not_active Application Discontinuation
- 2000-08-28 IL IL14842600A patent/IL148426A0/xx unknown
- 2000-08-28 EA EA200200301A patent/EA200200301A1/ru unknown
- 2000-08-28 JP JP2001519663A patent/JP2003508379A/ja not_active Withdrawn
- 2000-08-28 AT AT00959495T patent/ATE409688T1/de not_active IP Right Cessation
- 2000-08-28 MX MXPA02002038A patent/MXPA02002038A/es unknown
- 2000-08-28 EP EP00959495A patent/EP1212295B1/de not_active Expired - Lifetime
- 2000-08-28 WO PCT/US2000/023566 patent/WO2001016093A1/en active IP Right Grant
- 2000-08-28 AU AU70809/00A patent/AU775291B2/en not_active Ceased
- 2000-08-28 CN CNB008134464A patent/CN1235875C/zh not_active Expired - Fee Related
- 2000-08-28 CA CA002383002A patent/CA2383002A1/en not_active Abandoned
- 2000-08-28 DE DE60040397T patent/DE60040397D1/de not_active Expired - Fee Related
-
2002
- 2002-02-26 NO NO20020938A patent/NO20020938L/no unknown
Also Published As
Publication number | Publication date |
---|---|
JP2003508379A (ja) | 2003-03-04 |
WO2001016093A1 (en) | 2001-03-08 |
EA200200301A1 (ru) | 2002-08-29 |
CN1235875C (zh) | 2006-01-11 |
ATE409688T1 (de) | 2008-10-15 |
CN1382119A (zh) | 2002-11-27 |
US6495522B1 (en) | 2002-12-17 |
DE60040397D1 (de) | 2008-11-13 |
CA2383002A1 (en) | 2001-03-08 |
AU7080900A (en) | 2001-03-26 |
NO20020938D0 (no) | 2002-02-26 |
KR20020033777A (ko) | 2002-05-07 |
BR0013666A (pt) | 2002-05-14 |
EP1212295B1 (de) | 2008-10-01 |
IL148426A0 (en) | 2002-09-12 |
AU775291B2 (en) | 2004-07-29 |
MXPA02002038A (es) | 2002-10-31 |
EP1212295A1 (de) | 2002-06-12 |
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