NO20020217D0 - Nitrogenholdige heterobicykler som faktor Xa-inhibitorer - Google Patents

Nitrogenholdige heterobicykler som faktor Xa-inhibitorer

Info

Publication number
NO20020217D0
NO20020217D0 NO20020217A NO20020217A NO20020217D0 NO 20020217 D0 NO20020217 D0 NO 20020217D0 NO 20020217 A NO20020217 A NO 20020217A NO 20020217 A NO20020217 A NO 20020217A NO 20020217 D0 NO20020217 D0 NO 20020217D0
Authority
NO
Norway
Prior art keywords
inhibitors
factor
nitrogen
heterobicycles
same
Prior art date
Application number
NO20020217A
Other languages
English (en)
Other versions
NO20020217L (no
Inventor
Irina Cipora Jacobson
Mimi Lifen Quan
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of NO20020217D0 publication Critical patent/NO20020217D0/no
Publication of NO20020217L publication Critical patent/NO20020217L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20020217A 1999-07-16 2002-01-15 Nitrogenholdige heterobisykler som faktor Xa-inhibitorer NO20020217L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14434499P 1999-07-16 1999-07-16
PCT/US2000/018903 WO2001005784A1 (en) 1999-07-16 2000-07-12 NITROGEN CONTAINING HETEROBICYCLES AS FACTOR Xa INHIBITORS

Publications (2)

Publication Number Publication Date
NO20020217D0 true NO20020217D0 (no) 2002-01-15
NO20020217L NO20020217L (no) 2002-03-15

Family

ID=22508178

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20020217A NO20020217L (no) 1999-07-16 2002-01-15 Nitrogenholdige heterobisykler som faktor Xa-inhibitorer

Country Status (18)

Country Link
US (2) US6429205B1 (no)
EP (1) EP1196412B1 (no)
JP (1) JP2004507439A (no)
KR (1) KR20030011268A (no)
CN (1) CN1454211A (no)
AT (1) ATE268766T1 (no)
AU (1) AU2481501A (no)
BR (1) BR0013200A (no)
CA (1) CA2380727A1 (no)
DE (1) DE60011430T2 (no)
ES (1) ES2222257T3 (no)
HK (1) HK1045502B (no)
IL (1) IL147317A0 (no)
MX (1) MXPA02000537A (no)
NO (1) NO20020217L (no)
PL (1) PL357108A1 (no)
WO (1) WO2001005784A1 (no)
ZA (1) ZA200200094B (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6339099B1 (en) * 1997-06-20 2002-01-15 Dupont Pharmaceuticals Company Guanidine mimics as factor Xa inhibitors
ES2248084T3 (es) 1999-06-14 2006-03-16 Eli Lilly And Company Inhibidores de serinproteasa.
US6777413B2 (en) 2000-02-01 2004-08-17 Millennium Pharmaceuticals, Inc. 2-[1H]-quinolone and 2-[1H]-quinoxalone inhibitors of factor Xa
AU2001236606A1 (en) * 2000-02-01 2001-08-14 Cor Therapeutics, Inc. 3,4-dihydro-2h-benzo(1,4)oxazine inhibitors of factor xa
US7229986B2 (en) * 2000-05-16 2007-06-12 Takeda Pharmaceutical Company Ltd. Melanin-concentrating hormone antagonist
CA2409762A1 (en) 2000-06-23 2002-01-03 Donald J.P. Pinto Heteroaryl-phenyl substituted factor xa inhibitors
ES2290150T3 (es) 2000-06-23 2008-02-16 Bristol-Myers Squibb Pharma Company Derivados de pirazol condensados con 1-(heteroaril-fenilo) como inhibidores del factor xa.
TWI320039B (en) 2001-09-21 2010-02-01 Lactam-containing compounds and derivatives thereof as factor xa inhibitors
JP4249621B2 (ja) 2001-09-21 2009-04-02 ブリストル−マイヤーズ スクイブ カンパニー 第Ｘａ因子阻害剤としてのラクタム含有化合物およびその誘導体
TW200302225A (en) 2001-12-04 2003-08-01 Bristol Myers Squibb Co Substituted amino methyl factor Xa inhibitors
WO2003048081A2 (en) 2001-12-04 2003-06-12 Bristol-Myers Squibb Company Glycinamides as factor xa inhibitors
RU2315765C2 (ru) * 2002-01-22 2008-01-27 Е.И.Дюпон Де Немур Энд Компани Хиназолин(ди)оны, композиция для борьбы с насекомыми-вредителями, способ борьбы с насекомыми-вредителями, промежуточное соединение
WO2003082280A1 (en) 2002-03-26 2003-10-09 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
EP1505966A4 (en) 2002-05-10 2006-08-30 Bristol Myers Squibb Co 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA HEMMER
DE60322713D1 (de) * 2002-08-21 2008-09-18 Boehringer Ingelheim Pharma Substituierte dihydrochinoline als glucocorticoid-mmimetika,verfahren zu deren herstellung, pharmazeutische zubereitungen und deren verwendung
WO2004050637A2 (en) 2002-12-03 2004-06-17 Axys Pharmaceuticals, Inc. 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
EP1479678A1 (en) * 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH Pyrazole-derivatives as factor xa inhibitors
JP4585448B2 (ja) * 2002-12-23 2010-11-24 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 第Ｘａ因子阻害剤としてのピラゾール−誘導体
US7429581B2 (en) 2002-12-23 2008-09-30 Sanofi-Aventis Deutschland Gmbh Pyrazole-derivatives as factor Xa inhibitors
US7122557B2 (en) 2003-03-18 2006-10-17 Bristol-Myers Squibb Company Sulfonyl-amidino-containing and tetrahydropyrimidino-containing compounds as factor Xa inhibitors
US7129264B2 (en) * 2003-04-16 2006-10-31 Bristol-Myers Squibb Company Biarylmethyl indolines and indoles as antithromboembolic agents
UY28526A1 (es) 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
US20050124664A1 (en) * 2003-10-30 2005-06-09 Eric Sartori Urea thiadiazole inhibitors of plasminogen activator inhibior-1
US7795272B2 (en) 2004-03-13 2010-09-14 Boehringer Ingelheim Pharmaceutical, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
US7446210B2 (en) * 2004-10-26 2008-11-04 Janssen Pharmaceutica N.V. Factor Xa compounds
PE20060776A1 (es) 2004-12-27 2006-09-26 Boehringer Ingelheim Pharma Mimeticos de glucocorticoides, metodos para prepararlos y composiciones farmaceuticas
GT200600042A (es) * 2005-02-10 2006-09-27 Aventis Pharma Inc Compuestos de bis arilo y heteroarilo sustituido como antagonistas selectivos de 5ht2a
DE102005038947A1 (de) 2005-05-18 2006-11-30 Grünenthal GmbH Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln
KR20090097908A (ko) 2006-12-06 2009-09-16 베링거 인겔하임 인터내셔날 게엠베하 글루코코르티코이드 모사물, 이의 제조 방법, 이의 약제학적 조성물 및 용도
NZ580801A (en) * 2007-05-10 2012-09-28 Bristol Myers Squibb Co Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
KR20110020902A (ko) 2008-06-06 2011-03-03 베링거 인겔하임 인터내셔날 게엠베하 글루코코르티코이드 유사체, 이의 제조방법, 약제학적 조성물 및 이의 용도
US9260436B2 (en) 2012-06-22 2016-02-16 Sumitomo Chemical Company, Limited Fused heterocyclic compound
CN109475530B (zh) * 2016-05-23 2022-03-01 洛克菲勒大学 用于治疗自身免疫性疾病的氨酰基吲唑免疫调节剂

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2240946C (en) 1995-12-21 2002-09-10 The Dupont Merck Pharmaceutical Company Isoxazoline, isothiazoline and pyrazoline factor xa inhibitors
EP0946508B1 (en) * 1996-12-23 2009-09-23 Bristol-Myers Squibb Pharma Company NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS
JP2001506271A (ja) 1996-12-23 2001-05-15 デュポン ファーマシューティカルズ カンパニー Ｘａ因子阻害剤としての酸素またはイオウを含む複素環式芳香族化合物
ZA985247B (en) * 1997-06-19 1999-12-17 Du Pont Merck Pharma Guanidine mimics as factor Xa inhibitors.
WO1998057937A2 (en) 1997-06-19 1998-12-23 The Du Pont Merck Pharmaceutical Company Inhibitors of factor xa with a neutral p1 specificity group
EP1042299A1 (en) 1997-12-22 2000-10-11 Du Pont Pharmaceuticals Company Nitrogen containing heteroaromatics with ortho-substituted p1's as factor xa inhibitors

Also Published As

Publication number Publication date
DE60011430T2 (de) 2005-07-07
ATE268766T1 (de) 2004-06-15
HK1045502A1 (en) 2002-11-29
PL357108A1 (en) 2004-07-12
US20030096820A1 (en) 2003-05-22
CA2380727A1 (en) 2001-01-25
JP2004507439A (ja) 2004-03-11
EP1196412A1 (en) 2002-04-17
NO20020217L (no) 2002-03-15
WO2001005784A1 (en) 2001-01-25
CN1454211A (zh) 2003-11-05
KR20030011268A (ko) 2003-02-07
US6429205B1 (en) 2002-08-06
BR0013200A (pt) 2002-05-07
ES2222257T3 (es) 2005-02-01
AU2481501A (en) 2001-02-05
EP1196412B1 (en) 2004-06-09
IL147317A0 (en) 2002-08-14
HK1045502B (zh) 2004-12-10
US6716841B2 (en) 2004-04-06
ZA200200094B (en) 2003-04-30
DE60011430D1 (de) 2004-07-15
MXPA02000537A (es) 2004-09-10

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