NO20020217D0 - Nitrogenholdige heterobicykler som faktor Xa-inhibitorer - Google Patents

Nitrogenholdige heterobicykler som faktor Xa-inhibitorer

Info

Publication number
NO20020217D0
NO20020217D0 NO20020217A NO20020217A NO20020217D0 NO 20020217 D0 NO20020217 D0 NO 20020217D0 NO 20020217 A NO20020217 A NO 20020217A NO 20020217 A NO20020217 A NO 20020217A NO 20020217 D0 NO20020217 D0 NO 20020217D0
Authority
NO
Norway
Prior art keywords
inhibitors
factor
nitrogen
heterobicycles
same
Prior art date
Application number
NO20020217A
Other languages
English (en)
Other versions
NO20020217L (no
Inventor
Irina Cipora Jacobson
Mimi Lifen Quan
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of NO20020217D0 publication Critical patent/NO20020217D0/no
Publication of NO20020217L publication Critical patent/NO20020217L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20020217A 1999-07-16 2002-01-15 Nitrogenholdige heterobisykler som faktor Xa-inhibitorer NO20020217L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14434499P 1999-07-16 1999-07-16
PCT/US2000/018903 WO2001005784A1 (en) 1999-07-16 2000-07-12 NITROGEN CONTAINING HETEROBICYCLES AS FACTOR Xa INHIBITORS

Publications (2)

Publication Number Publication Date
NO20020217D0 true NO20020217D0 (no) 2002-01-15
NO20020217L NO20020217L (no) 2002-03-15

Family

ID=22508178

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20020217A NO20020217L (no) 1999-07-16 2002-01-15 Nitrogenholdige heterobisykler som faktor Xa-inhibitorer

Country Status (18)

Country Link
US (2) US6429205B1 (no)
EP (1) EP1196412B1 (no)
JP (1) JP2004507439A (no)
KR (1) KR20030011268A (no)
CN (1) CN1454211A (no)
AT (1) ATE268766T1 (no)
AU (1) AU2481501A (no)
BR (1) BR0013200A (no)
CA (1) CA2380727A1 (no)
DE (1) DE60011430T2 (no)
ES (1) ES2222257T3 (no)
HK (1) HK1045502B (no)
IL (1) IL147317A0 (no)
MX (1) MXPA02000537A (no)
NO (1) NO20020217L (no)
PL (1) PL357108A1 (no)
WO (1) WO2001005784A1 (no)
ZA (1) ZA200200094B (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6339099B1 (en) * 1997-06-20 2002-01-15 Dupont Pharmaceuticals Company Guanidine mimics as factor Xa inhibitors
EP1192132B1 (en) 1999-06-14 2005-09-07 Eli Lilly And Company Serine protease inhibitors
WO2001057021A2 (en) 2000-02-01 2001-08-09 Cor Therapeutics, Inc. 2-[1H]-QUINOLONE AND 2-[1H]-QUINOXALONE INHIBITORS OF FACTOR Xa
EP1255743A1 (en) * 2000-02-01 2002-11-13 Millenium Pharmaceuticals, Inc. 3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE INHIBITORS OF FACTOR Xa
EP1283199A4 (en) * 2000-05-16 2003-12-17 Takeda Chemical Industries Ltd MELANIN CONCENTRATION HORMONE ANTAGONIST
WO2002000647A1 (en) 2000-06-23 2002-01-03 Bristol-Myers Squibb Pharma Company Heteroaryl-phenyl substituted factor xa inhibitors
JP2004501918A (ja) 2000-06-23 2004-01-22 ブリストル−マイヤーズ　スクイブ　ファーマ　カンパニー Ｘａ因子阻害剤としての１−（ヘテロアリール−フェニル）−縮合ピラゾール誘導体
RS20080517A (en) 2001-09-21 2009-07-15 Bristol-Myers Squibb Company, Lactam containing compounds and derivatives thereof as factor xa inhibitors
TWI320039B (en) 2001-09-21 2010-02-01 Lactam-containing compounds and derivatives thereof as factor xa inhibitors
WO2003048081A2 (en) 2001-12-04 2003-06-12 Bristol-Myers Squibb Company Glycinamides as factor xa inhibitors
TW200302225A (en) 2001-12-04 2003-08-01 Bristol Myers Squibb Co Substituted amino methyl factor Xa inhibitors
ES2427141T3 (es) 2002-01-22 2013-10-29 E. I. Du Pont De Nemours And Company Quinazolina(di)onas para el control de plagas de invertebrados
CN1633296A (zh) 2002-03-26 2005-06-29 贝林格尔·英格海姆药物公司 糖皮质素模拟物、其制备方法、药物组合物及其用途
US7312214B2 (en) 2002-05-10 2007-12-25 Bristol-Myers Squibb Company 1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors
JP2006504678A (ja) * 2002-08-21 2006-02-09 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド グルココルチコイドミメチックス、その製造方法、その医薬組成物、及び使用
PT1569912E (pt) 2002-12-03 2015-09-15 Pharmacyclics Llc Derivados 2-(2-hidroxibifenil-3-il)-1h-benzoimidazole-5- carboxamidina como inibidores do fator viia
US7429581B2 (en) 2002-12-23 2008-09-30 Sanofi-Aventis Deutschland Gmbh Pyrazole-derivatives as factor Xa inhibitors
MXPA05006200A (es) * 2002-12-23 2005-08-19 Aventis Pharma Gmbh Derivados de pirazol como inhibidores del factor xa.
EP1479678A1 (en) * 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH Pyrazole-derivatives as factor xa inhibitors
US7122557B2 (en) 2003-03-18 2006-10-17 Bristol-Myers Squibb Company Sulfonyl-amidino-containing and tetrahydropyrimidino-containing compounds as factor Xa inhibitors
US7129264B2 (en) * 2003-04-16 2006-10-31 Bristol-Myers Squibb Company Biarylmethyl indolines and indoles as antithromboembolic agents
UY28526A1 (es) 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
US20050124664A1 (en) * 2003-10-30 2005-06-09 Eric Sartori Urea thiadiazole inhibitors of plasminogen activator inhibior-1
US7795272B2 (en) 2004-03-13 2010-09-14 Boehringer Ingelheim Pharmaceutical, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
AU2005299693B2 (en) * 2004-10-26 2012-07-05 Janssen Pharmaceutica, N.V. Factor Xa compounds
ES2326907T3 (es) 2004-12-27 2009-10-21 Boehringer Ingelheim Pharmaceuticals Inc. Mimeticos de glucocorticoides, metodos para su preparacion, composiciones farmaceuticas y su uso.
GT200600042A (es) * 2005-02-10 2006-09-27 Aventis Pharma Inc Compuestos de bis arilo y heteroarilo sustituido como antagonistas selectivos de 5ht2a
DE102005038947A1 (de) 2005-05-18 2006-11-30 Grünenthal GmbH Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln
WO2008070507A2 (en) 2006-12-06 2008-06-12 Boehringer Ingelheim International Gmbh Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
MX2009011923A (es) * 2007-05-10 2009-11-18 Amr Technology Inc Tetrahidrobenzo-1,4-diazepinas aril- y heteroaril-sustituidas y uso de las mismas para bloquear reabsorcion de norepinefrina, dopamina y serotonina.
MX2010013095A (es) 2008-06-06 2010-12-21 Boehringer Ingelheim Int Mimeticos de glucocorticoides, metodos para su fabricacion, composiciones farmaceuticas y usos de los mismos.
EP2865671B1 (en) * 2012-06-22 2017-11-01 Sumitomo Chemical Company, Ltd Fused heterocyclic compound
WO2017205296A1 (en) * 2016-05-23 2017-11-30 The Rockefeller University Aminoacylindazole immunomodulators for treatment of autoimmune diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1335897A (en) 1995-12-21 1997-07-17 Du Pont Merck Pharmaceutical Company, The Isoxazoline, isothiazoline and pyrazoline factor xa inhibitors
AU6645998A (en) 1996-12-23 1998-07-17 Du Pont Pharmaceuticals Company Oxygen or sulfur containing heteroaromatics as factor xa inhibitors
AU730224B2 (en) * 1996-12-23 2001-03-01 Du Pont Pharmaceuticals Company Nitrogen containing heteroaromatics as factor Xa inhibitors
JP2002507968A (ja) 1997-06-19 2002-03-12 デュポン ファーマシューティカルズ カンパニー 中性のＰ１特異性基を有するＸａ因子阻害剤
ZA985247B (en) * 1997-06-19 1999-12-17 Du Pont Merck Pharma Guanidine mimics as factor Xa inhibitors.
CA2314401A1 (en) 1997-12-22 1999-07-01 Du Pont Pharmaceuticals Company Nitrogen containing heteroaromatics with ortho-substituted p1's as factor xa inhibitors

Also Published As

Publication number Publication date
CN1454211A (zh) 2003-11-05
DE60011430T2 (de) 2005-07-07
CA2380727A1 (en) 2001-01-25
PL357108A1 (en) 2004-07-12
NO20020217L (no) 2002-03-15
HK1045502B (zh) 2004-12-10
US6429205B1 (en) 2002-08-06
HK1045502A1 (en) 2002-11-29
DE60011430D1 (de) 2004-07-15
BR0013200A (pt) 2002-05-07
US6716841B2 (en) 2004-04-06
AU2481501A (en) 2001-02-05
IL147317A0 (en) 2002-08-14
ES2222257T3 (es) 2005-02-01
WO2001005784A1 (en) 2001-01-25
ZA200200094B (en) 2003-04-30
KR20030011268A (ko) 2003-02-07
JP2004507439A (ja) 2004-03-11
ATE268766T1 (de) 2004-06-15
MXPA02000537A (es) 2004-09-10
US20030096820A1 (en) 2003-05-22
EP1196412B1 (en) 2004-06-09
EP1196412A1 (en) 2002-04-17

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FC2A Withdrawal, rejection or dismissal of laid open patent application