NO20013159L - Kombinasjoner av ileumgallesyretransportinhibitorer og gallesyresekvestreringsmidler for kardiovaskulore indikasjoner - Google Patents
Kombinasjoner av ileumgallesyretransportinhibitorer og gallesyresekvestreringsmidler for kardiovaskulore indikasjonerInfo
- Publication number
- NO20013159L NO20013159L NO20013159A NO20013159A NO20013159L NO 20013159 L NO20013159 L NO 20013159L NO 20013159 A NO20013159 A NO 20013159A NO 20013159 A NO20013159 A NO 20013159A NO 20013159 L NO20013159 L NO 20013159L
- Authority
- NO
- Norway
- Prior art keywords
- bile acid
- combinations
- ileum
- transport inhibitors
- cardiovascular indications
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11395598P | 1998-12-23 | 1998-12-23 | |
US14304399P | 1999-07-07 | 1999-07-07 | |
PCT/US1999/027949 WO2000038728A1 (en) | 1998-12-23 | 1999-12-17 | Combinations of ileal bile acid transport inhibitors and bile acid sequestring agents for cardiovascular indications |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20013159D0 NO20013159D0 (no) | 2001-06-22 |
NO20013159L true NO20013159L (no) | 2001-08-22 |
Family
ID=26811681
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20013159A NO20013159L (no) | 1998-12-23 | 2001-06-22 | Kombinasjoner av ileumgallesyretransportinhibitorer og gallesyresekvestreringsmidler for kardiovaskulore indikasjoner |
Country Status (24)
Country | Link |
---|---|
US (2) | US6562860B1 (no) |
EP (1) | EP1140190B1 (no) |
JP (1) | JP2002533414A (no) |
KR (1) | KR20010102965A (no) |
CN (1) | CN1338945A (no) |
AR (1) | AR022022A1 (no) |
AT (1) | ATE228012T1 (no) |
AU (1) | AU776953B2 (no) |
BR (1) | BR9916484A (no) |
CA (1) | CA2356156A1 (no) |
CZ (1) | CZ20012345A3 (no) |
DE (1) | DE69904079T2 (no) |
DK (1) | DK1140190T3 (no) |
EA (1) | EA004877B1 (no) |
ES (1) | ES2189529T3 (no) |
HK (1) | HK1044292A1 (no) |
HU (1) | HUP0104745A3 (no) |
IL (1) | IL143943A0 (no) |
MX (1) | MXPA01006470A (no) |
NO (1) | NO20013159L (no) |
NZ (1) | NZ512535A (no) |
PL (1) | PL348609A1 (no) |
PT (1) | PT1140190E (no) |
WO (1) | WO2000038728A1 (no) |
Families Citing this family (56)
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SE0000772D0 (sv) | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | Chemical compounds |
KR100782245B1 (ko) * | 2000-11-28 | 2007-12-05 | 미쯔비시 웰 파마 가부시키가이샤 | 축적성 염소함유 화합물의 배설 촉진제 |
EG26979A (en) | 2000-12-21 | 2015-03-01 | Astrazeneca Ab | Chemical compounds |
CA2444028A1 (en) * | 2001-04-18 | 2002-10-31 | Genzyme Corporation | Methods of treating syndrome x with aliphatic polyamines |
GB0121337D0 (en) | 2001-09-04 | 2001-10-24 | Astrazeneca Ab | Chemical compounds |
GB0121621D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
GB0121622D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
EP1427423B9 (en) | 2001-09-08 | 2017-12-20 | AstraZeneca AB | Benzothiazepine and benzothiadiazepine derivatives with ileal bile acid transport (ibat) inhibitory activity for the treatment hyperlipidaemia |
GB0209467D0 (en) | 2002-04-25 | 2002-06-05 | Astrazeneca Ab | Chemical compounds |
GB0213669D0 (en) | 2002-06-14 | 2002-07-24 | Astrazeneca Ab | Chemical compounds |
GB0304194D0 (en) | 2003-02-25 | 2003-03-26 | Astrazeneca Ab | Chemical compounds |
GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
EP2995317A1 (en) | 2010-05-26 | 2016-03-16 | Satiogen Pharmaceuticals, Inc. | Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions |
RU2619215C2 (ru) * | 2010-11-08 | 2017-05-12 | Альбирео Аб | Фармацевтическая комбинация, включающая ibat-ингибитор и связующее желчной кислоты |
ES2586931T3 (es) | 2010-11-08 | 2016-10-19 | Albireo Ab | Inhibidores de IBAT para el tratamiento de enfermedades hepáticas |
JP2012171911A (ja) | 2011-02-22 | 2012-09-10 | Kao Corp | Ppar活性化剤 |
SG10201909122QA (en) | 2011-10-28 | 2019-11-28 | Lumena Pharmaceuticals Inc | Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases |
EA038594B1 (ru) | 2011-10-28 | 2021-09-21 | Шайр Хьюман Дженетик Терапис, Инк. | Ингибиторы рециркуляции желчных кислот для лечения гиперхолемии и холестатического заболевания печени |
WO2014144485A1 (en) | 2013-03-15 | 2014-09-18 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of barrett's esophagus and gastroesophageal reflux disease |
CA2907230A1 (en) | 2013-03-15 | 2014-09-18 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease |
JO3301B1 (ar) | 2013-04-26 | 2018-09-16 | Albireo Ab | تعديلات بلورية على إيلوبيكسيبات |
US10709755B2 (en) | 2014-06-25 | 2020-07-14 | Elobix Ab | Solid formulation and method for preventing or reducing coloration thereof |
EP3012252A1 (en) | 2014-10-24 | 2016-04-27 | Ferring BV | Crystal modifications of elobixibat |
US10441604B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Cholestyramine pellets and methods for preparation thereof |
US10786529B2 (en) | 2016-02-09 | 2020-09-29 | Albireo Ab | Oral cholestyramine formulation and use thereof |
CN108601745B (zh) | 2016-02-09 | 2021-12-07 | 阿尔比里奥公司 | 口服考来烯胺制剂及其用途 |
US10441605B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Oral cholestyramine formulation and use thereof |
CA3011565C (en) | 2016-02-09 | 2024-01-02 | Albireo Ab | Oral cholestyramine formulation and use thereof |
WO2019032026A1 (en) | 2017-08-09 | 2019-02-14 | Albireo Ab | CHOLESTYRAMINE GRANULES, ORAL FORMULATIONS OF CHOLESTYRAMINE AND THEIR USE |
CA3071182A1 (en) | 2017-08-09 | 2019-02-14 | Albireo Ab | Cholestyramine pellets, oral cholestyramine formulations and use thereof |
US10793534B2 (en) | 2018-06-05 | 2020-10-06 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
CN112449637B (zh) | 2018-06-05 | 2024-03-19 | 阿尔比里奥公司 | 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途 |
JP7448490B2 (ja) | 2018-06-20 | 2024-03-12 | アルビレオ・アクチボラグ | オデビキシバットの医薬製剤 |
US11801226B2 (en) | 2018-06-20 | 2023-10-31 | Albireo Ab | Pharmaceutical formulation of odevixibat |
US11007142B2 (en) | 2018-08-09 | 2021-05-18 | Albireo Ab | Oral cholestyramine formulation and use thereof |
US10722457B2 (en) | 2018-08-09 | 2020-07-28 | Albireo Ab | Oral cholestyramine formulation and use thereof |
US11549878B2 (en) | 2018-08-09 | 2023-01-10 | Albireo Ab | In vitro method for determining the adsorbing capacity of an insoluble adsorbant |
US10941127B2 (en) | 2019-02-06 | 2021-03-09 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
WO2020161216A1 (en) | 2019-02-06 | 2020-08-13 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
MX2021008981A (es) | 2019-02-06 | 2021-09-08 | Albireo Ab | Compuestos de benzotiadiazepina y su uso como moduladores del acido biliar. |
US10975045B2 (en) | 2019-02-06 | 2021-04-13 | Aibireo AB | Benzothiazepine compounds and their use as bile acid modulators |
MX2021009625A (es) | 2019-02-12 | 2021-11-04 | Mirum Pharmaceuticals Inc | Métodos para incrementar el crecimiento en sujetos pediátricos que tienen enfermedad de hígado colestásico. |
WO2021110883A1 (en) | 2019-12-04 | 2021-06-10 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
WO2021110884A1 (en) | 2019-12-04 | 2021-06-10 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
TW202134220A (zh) | 2019-12-04 | 2021-09-16 | 瑞典商艾爾比瑞歐公司 | 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途 |
FI4069360T3 (fi) | 2019-12-04 | 2024-02-20 | Albireo Ab | Bentsotia(di)atsepiinin yhdisteet ja niiden käyttö sappihapon modulaattoreina |
WO2021110887A1 (en) | 2019-12-04 | 2021-06-10 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
JP2023504643A (ja) | 2019-12-04 | 2023-02-06 | アルビレオ・アクチボラグ | ベンゾチア(ジ)アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 |
JP2023504647A (ja) | 2019-12-04 | 2023-02-06 | アルビレオ・アクチボラグ | ベンゾチア(ジ)アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 |
TW202134221A (zh) | 2019-12-04 | 2021-09-16 | 瑞典商艾爾比瑞歐公司 | 苯并噻二氮呯化合物及其作為膽酸調節劑之用途 |
US11014898B1 (en) | 2020-12-04 | 2021-05-25 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
CA3158184A1 (en) | 2019-12-04 | 2021-08-10 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
JP2023537285A (ja) | 2020-08-03 | 2023-08-31 | アルビレオ・アクチボラグ | ベンゾチア(ジ)アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 |
EP4243831A1 (en) | 2020-11-12 | 2023-09-20 | Albireo AB | Odevixibat for treating progressive familial intrahepatic cholestasis (pfic) |
CN116583504A (zh) | 2020-12-04 | 2023-08-11 | 阿尔比里奥公司 | 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途 |
WO2023237728A1 (en) | 2022-06-09 | 2023-12-14 | Albireo Ab | Treating hepatitis |
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-
1999
- 1999-12-17 AU AU23480/00A patent/AU776953B2/en not_active Ceased
- 1999-12-17 WO PCT/US1999/027949 patent/WO2000038728A1/en not_active Application Discontinuation
- 1999-12-17 PT PT99967140T patent/PT1140190E/pt unknown
- 1999-12-17 JP JP2000590679A patent/JP2002533414A/ja active Pending
- 1999-12-17 PL PL99348609A patent/PL348609A1/xx not_active Application Discontinuation
- 1999-12-17 EP EP99967140A patent/EP1140190B1/en not_active Revoked
- 1999-12-17 DE DE69904079T patent/DE69904079T2/de not_active Expired - Fee Related
- 1999-12-17 AT AT99967140T patent/ATE228012T1/de not_active IP Right Cessation
- 1999-12-17 IL IL14394399A patent/IL143943A0/xx unknown
- 1999-12-17 BR BR9916484-1A patent/BR9916484A/pt not_active IP Right Cessation
- 1999-12-17 US US09/466,592 patent/US6562860B1/en not_active Expired - Fee Related
- 1999-12-17 EA EA200100702A patent/EA004877B1/ru not_active IP Right Cessation
- 1999-12-17 HU HU0104745A patent/HUP0104745A3/hu unknown
- 1999-12-17 CZ CZ20012345A patent/CZ20012345A3/cs unknown
- 1999-12-17 NZ NZ512535A patent/NZ512535A/en unknown
- 1999-12-17 DK DK99967140T patent/DK1140190T3/da active
- 1999-12-17 ES ES99967140T patent/ES2189529T3/es not_active Expired - Lifetime
- 1999-12-17 CA CA002356156A patent/CA2356156A1/en not_active Abandoned
- 1999-12-17 MX MXPA01006470A patent/MXPA01006470A/es unknown
- 1999-12-17 CN CN99816267A patent/CN1338945A/zh active Pending
- 1999-12-17 KR KR1020017008090A patent/KR20010102965A/ko not_active Application Discontinuation
- 1999-12-23 AR ARP990106753A patent/AR022022A1/es not_active Application Discontinuation
-
2001
- 2001-06-22 NO NO20013159A patent/NO20013159L/no not_active Application Discontinuation
-
2002
- 2002-08-15 HK HK02105982.7A patent/HK1044292A1/zh unknown
-
2003
- 2003-02-26 US US10/373,180 patent/US20040029845A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
PL348609A1 (en) | 2002-06-03 |
CA2356156A1 (en) | 2000-07-06 |
ES2189529T3 (es) | 2003-07-01 |
EP1140190B1 (en) | 2002-11-20 |
AU776953B2 (en) | 2004-09-30 |
JP2002533414A (ja) | 2002-10-08 |
HUP0104745A3 (en) | 2003-01-28 |
PT1140190E (pt) | 2003-02-28 |
EA004877B1 (ru) | 2004-08-26 |
DE69904079T2 (de) | 2003-07-17 |
US20040029845A1 (en) | 2004-02-12 |
AU2348000A (en) | 2000-07-31 |
DE69904079D1 (de) | 2003-01-02 |
CN1338945A (zh) | 2002-03-06 |
NO20013159D0 (no) | 2001-06-22 |
EP1140190A1 (en) | 2001-10-10 |
WO2000038728A1 (en) | 2000-07-06 |
KR20010102965A (ko) | 2001-11-17 |
EA200100702A1 (ru) | 2001-12-24 |
BR9916484A (pt) | 2002-01-22 |
DK1140190T3 (da) | 2002-12-23 |
IL143943A0 (en) | 2002-04-21 |
US6562860B1 (en) | 2003-05-13 |
CZ20012345A3 (cs) | 2001-12-12 |
ATE228012T1 (de) | 2002-12-15 |
MXPA01006470A (es) | 2003-06-06 |
HK1044292A1 (zh) | 2002-10-18 |
AR022022A1 (es) | 2002-09-04 |
NZ512535A (en) | 2003-12-19 |
HUP0104745A2 (hu) | 2002-04-29 |
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