NO20011270L - Tricykliske <delta>3-piperidiner som <alfa>2-antagonister - Google Patents

Tricykliske <delta>3-piperidiner som <alfa>2-antagonister

Info

Publication number
NO20011270L
NO20011270L NO20011270A NO20011270A NO20011270L NO 20011270 L NO20011270 L NO 20011270L NO 20011270 A NO20011270 A NO 20011270A NO 20011270 A NO20011270 A NO 20011270A NO 20011270 L NO20011270 L NO 20011270L
Authority
NO
Norway
Prior art keywords
parta
piperidines
alfa
tricyclic
antagonists
Prior art date
Application number
NO20011270A
Other languages
English (en)
Norwegian (no)
Other versions
NO20011270D0 (no
Inventor
Ludo Edmond Josephine Kennis
Frans Maria Alfons Van Keybus
Josephus Carolus Mertens
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20011270D0 publication Critical patent/NO20011270D0/no
Publication of NO20011270L publication Critical patent/NO20011270L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
NO20011270A 1998-10-06 2001-03-13 Tricykliske <delta>3-piperidiner som <alfa>2-antagonister NO20011270L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98203370 1998-10-06
PCT/EP1999/007419 WO2000020421A2 (en) 1998-10-06 1999-10-01 TRICYCLIC Δ3-PIPERIDINES AS α2-ANTAGONISTS

Publications (2)

Publication Number Publication Date
NO20011270D0 NO20011270D0 (no) 2001-03-13
NO20011270L true NO20011270L (no) 2001-03-13

Family

ID=8234191

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20011270A NO20011270L (no) 1998-10-06 2001-03-13 Tricykliske <delta>3-piperidiner som <alfa>2-antagonister

Country Status (31)

Country Link
US (1) US6495555B1 (ja)
EP (1) EP1119571B1 (ja)
JP (1) JP4590101B2 (ja)
KR (1) KR20010071843A (ja)
CN (1) CN1131230C (ja)
AR (1) AR024216A1 (ja)
AT (1) ATE232869T1 (ja)
AU (1) AU760502B2 (ja)
BG (1) BG64872B1 (ja)
BR (1) BR9913507A (ja)
CA (1) CA2345622C (ja)
CZ (1) CZ20011104A3 (ja)
DE (1) DE69905478T2 (ja)
DK (1) DK1119571T3 (ja)
EE (1) EE04770B1 (ja)
ES (1) ES2193751T3 (ja)
HK (1) HK1038010A1 (ja)
HU (1) HUP0104002A3 (ja)
ID (1) ID28032A (ja)
IL (1) IL142443A0 (ja)
NO (1) NO20011270L (ja)
NZ (1) NZ510115A (ja)
PL (1) PL347894A1 (ja)
PT (1) PT1119571E (ja)
RU (1) RU2230744C2 (ja)
SI (1) SI1119571T1 (ja)
SK (1) SK285585B6 (ja)
TR (1) TR200100952T2 (ja)
TW (1) TWI248441B (ja)
UA (1) UA69420C2 (ja)
WO (1) WO2000020421A2 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20011105A3 (cs) * 1998-10-06 2001-12-12 Janssen Pharmaceutica N. V. Tricyklické delta3-piperidiny jako farmaceutika
CA2480266C (en) * 2002-04-03 2011-07-12 Orion Corporation Use of an alpha2-adrenoreceptor antagonist for cns-related diseases
CA2562406C (en) 2004-04-12 2013-03-19 Taisho Pharmaceutical Co., Ltd. Cyclic amine compound
US20060035939A1 (en) * 2004-07-14 2006-02-16 Japan Tobacco Inc. 3-Aminobenzamide compounds and inhibitors of vanilloid receptor subtype 1 (VR1) activity
RU2392278C2 (ru) * 2004-07-15 2010-06-20 Джапан Тобакко Инк. Конденсированное производное бензамида и ингибитор активности подтипа 1 рецептора ваниллоида (vr1)
US7906508B2 (en) * 2005-12-28 2011-03-15 Japan Tobacco Inc. 3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity
US8399465B2 (en) 2009-05-14 2013-03-19 Janssen Pharmaceutica Nv Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene A4 hydrolase
JOP20200052A1 (ar) * 2013-12-19 2017-06-16 Bayer Pharma AG بيبريدينيل تتراهيدرو كوينولينات مستبدلة واستخدامها كمعضدات مستقبل أدريني ألفا- 2c
US9624199B2 (en) 2013-12-19 2017-04-18 Bayer Pharma Aktiengesellschaft Substituted bipiperidinyl derivatives
CA2934133A1 (en) * 2013-12-19 2015-06-25 Bayer Pharma Aktiengesellschaft Substituted piperidinyl-tetrahydroquinolines
CN114276359B (zh) * 2022-01-05 2023-05-05 浙江大学 一种1,2,3,4-四氢苯并[4,5]呋喃[2,3-c]吡啶衍生物的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3522959A1 (de) 1985-06-27 1987-01-08 Merck Patent Gmbh Indolderivate
US4673680A (en) * 1985-09-18 1987-06-16 Pendleton Robert G α2 -adrenergic receptor antagonists as modifiers of gastrointestinal motility
US4985422A (en) * 1988-04-27 1991-01-15 Glaxo Group Limited Lactam derivatives
US4971974A (en) * 1988-06-16 1990-11-20 Neurex Corporation Benzothiophenes as appetite suppressants
US5100891A (en) * 1991-01-18 1992-03-31 Hoechst-Roussel Pharmaceuticals Inc. Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds
PT942911E (pt) * 1996-12-06 2002-04-29 Abbott Lab Compostos alfa 1 adrenergicos de benzopiranopirrolo e benzopiranopiridina
CN1129578C (zh) * 1997-12-25 2003-12-03 明治制果株式会社 四氢苯并吲哚衍生物
CZ20011105A3 (cs) * 1998-10-06 2001-12-12 Janssen Pharmaceutica N. V. Tricyklické delta3-piperidiny jako farmaceutika

Also Published As

Publication number Publication date
HUP0104002A2 (hu) 2002-03-28
DE69905478T2 (de) 2004-03-18
SK4322001A3 (en) 2002-01-07
CN1131230C (zh) 2003-12-17
PT1119571E (pt) 2003-06-30
TWI248441B (en) 2006-02-01
ES2193751T3 (es) 2003-11-01
IL142443A0 (en) 2002-03-10
CA2345622A1 (en) 2000-04-13
NO20011270D0 (no) 2001-03-13
CZ20011104A3 (cs) 2001-12-12
SI1119571T1 (en) 2003-08-31
WO2000020421A3 (en) 2000-08-03
US6495555B1 (en) 2002-12-17
AU760502B2 (en) 2003-05-15
BG105332A (en) 2001-11-30
KR20010071843A (ko) 2001-07-31
ID28032A (id) 2001-05-03
AU6334199A (en) 2000-04-26
CN1332744A (zh) 2002-01-23
EE04770B1 (et) 2007-02-15
BR9913507A (pt) 2001-06-05
AR024216A1 (es) 2002-09-25
NZ510115A (en) 2002-11-26
HK1038010A1 (en) 2002-03-01
SK285585B6 (sk) 2007-04-05
DE69905478D1 (de) 2003-03-27
PL347894A1 (en) 2002-04-22
RU2230744C2 (ru) 2004-06-20
BG64872B1 (bg) 2006-07-31
CA2345622C (en) 2007-12-04
HUP0104002A3 (en) 2003-12-29
TR200100952T2 (tr) 2001-10-22
JP2002526545A (ja) 2002-08-20
ATE232869T1 (de) 2003-03-15
EP1119571A2 (en) 2001-08-01
UA69420C2 (uk) 2004-09-15
EE200100209A (et) 2002-06-17
WO2000020421A2 (en) 2000-04-13
DK1119571T3 (da) 2003-05-26
JP4590101B2 (ja) 2010-12-01
EP1119571B1 (en) 2003-02-19

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