NO20006572L - Medikamenter inneholdende bisfosfonsyrer og deres derivater for forhindring og behandling av autoimmune sykdommer og allergier - Google Patents
Medikamenter inneholdende bisfosfonsyrer og deres derivater for forhindring og behandling av autoimmune sykdommer og allergierInfo
- Publication number
- NO20006572L NO20006572L NO20006572A NO20006572A NO20006572L NO 20006572 L NO20006572 L NO 20006572L NO 20006572 A NO20006572 A NO 20006572A NO 20006572 A NO20006572 A NO 20006572A NO 20006572 L NO20006572 L NO 20006572L
- Authority
- NO
- Norway
- Prior art keywords
- acid
- derivatives
- bisphosphonic
- autoimmune diseases
- bisphosphonic acids
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 8
- 150000007513 acids Chemical class 0.000 title abstract 5
- 208000023275 Autoimmune disease Diseases 0.000 title abstract 3
- 206010020751 Hypersensitivity Diseases 0.000 title abstract 3
- 230000007815 allergy Effects 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- KBPGKWPDIYMIFV-UHFFFAOYSA-N (2-amino-2-imino-1-phosphonoethyl)phosphonic acid Chemical compound NC(=N)C(P(O)(O)=O)P(O)(O)=O KBPGKWPDIYMIFV-UHFFFAOYSA-N 0.000 abstract 1
- NHAOLKGXQFICNN-UHFFFAOYSA-N (amino-hydroxy-phosphonomethyl)phosphonic acid Chemical compound OP(=O)(O)C(O)(N)P(O)(O)=O NHAOLKGXQFICNN-UHFFFAOYSA-N 0.000 abstract 1
- MPBVHIBUJCELCL-UHFFFAOYSA-N Ibandronate Chemical compound CCCCCN(C)CCC(O)(P(O)(O)=O)P(O)(O)=O MPBVHIBUJCELCL-UHFFFAOYSA-N 0.000 abstract 1
- 206010028372 Muscular weakness Diseases 0.000 abstract 1
- IIDJRNMFWXDHID-UHFFFAOYSA-N Risedronic acid Chemical compound OP(=O)(O)C(P(O)(O)=O)(O)CC1=CC=CN=C1 IIDJRNMFWXDHID-UHFFFAOYSA-N 0.000 abstract 1
- 206010039710 Scleroderma Diseases 0.000 abstract 1
- DKJJVAGXPKPDRL-UHFFFAOYSA-N Tiludronic acid Chemical compound OP(O)(=O)C(P(O)(O)=O)SC1=CC=C(Cl)C=C1 DKJJVAGXPKPDRL-UHFFFAOYSA-N 0.000 abstract 1
- 206010046851 Uveitis Diseases 0.000 abstract 1
- 239000013566 allergen Substances 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 229960005236 ibandronic acid Drugs 0.000 abstract 1
- 229950006971 incadronic acid Drugs 0.000 abstract 1
- LWRDQHOZTAOILO-UHFFFAOYSA-N incadronic acid Chemical compound OP(O)(=O)C(P(O)(O)=O)NC1CCCCCC1 LWRDQHOZTAOILO-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000036473 myasthenia Effects 0.000 abstract 1
- WRUUGTRCQOWXEG-UHFFFAOYSA-N pamidronate Chemical compound NCCC(O)(P(O)(O)=O)P(O)(O)=O WRUUGTRCQOWXEG-UHFFFAOYSA-N 0.000 abstract 1
- 229960003978 pamidronic acid Drugs 0.000 abstract 1
- 239000000575 pesticide Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 229960000759 risedronic acid Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 229960005324 tiludronic acid Drugs 0.000 abstract 1
- 229960004276 zoledronic acid Drugs 0.000 abstract 1
- XRASPMIURGNCCH-UHFFFAOYSA-N zoledronic acid Chemical compound OP(=O)(O)C(P(O)(O)=O)(O)CN1C=CN=C1 XRASPMIURGNCCH-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Abstract
Anvendelse av bisfosfonsyrer og deri- vater derav for fremstilling av farma- søytiske preparater for å forebygge og behandle autoimmunsykdommer eller aller- gier, i kombinasjon med de autoantigener som spesifikt anvendes for å behandle den respektive allergi. Noen eksempler på bisfosfonsyrene og derivatene derav som anvendes i henhold til oppfinnelsen, er aminohydroksymetyliden-bisfosfonsyre (AMP), 2-amino-l-hydroksyetyliden-l,1- bisfosfonsyre (AEP), pamidronsyre, alen- dronsyre, 6-amino-l-hydroksyheksyliden- 1,1-bisfosfonsyre (AHP), amidinometylen- bisfosfonsyre (AIMP), ibandronsyre, risedronsyre, zoledronsyre, cimadronsyre og tiludronsyre. Noen eksempler på auto- immunsykdommer for hvilke bisfosfonsyrer eller derivater derav kan anvendes, inn- befatter revmatoid artritt, myasthenia gråvis, diabetes mellitus, uveitis og skleroderma. Bisfosfonsyrene eller deri- vatene derav og autoantigenene eller allergenene kan anvendes samtidig eller etter hverandre. Preparatene på basis av kombinasjonene kan anvendes i fast form, som salter, som oppløsninger eller som sprøytemidler.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19828450A DE19828450A1 (de) | 1998-06-26 | 1998-06-26 | Bisphosphonsäuren und deren Derivate enthaltende Arzneimittel zur Prophylaxe und zur Behandlung von Autoimmunkrankheiten sowie von Allergien |
| PCT/DE1999/001844 WO2000000182A2 (de) | 1998-06-26 | 1999-06-24 | Bisphosphonsäuren und deren derivate enthaltende arzneimittel zur prophylaxe und zur behandlung von autoimmunkrankheiten sowie von allergien |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20006572D0 NO20006572D0 (no) | 2000-12-21 |
| NO20006572L true NO20006572L (no) | 2001-02-21 |
Family
ID=7872064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20006572A NO20006572L (no) | 1998-06-26 | 2000-12-21 | Medikamenter inneholdende bisfosfonsyrer og deres derivater for forhindring og behandling av autoimmune sykdommer og allergier |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1089761B1 (no) |
| JP (1) | JP2002519319A (no) |
| KR (1) | KR20010053211A (no) |
| AT (1) | ATE224734T1 (no) |
| AU (1) | AU740605B2 (no) |
| CA (1) | CA2334711C (no) |
| DE (2) | DE19828450A1 (no) |
| DK (1) | DK1089761T3 (no) |
| EA (1) | EA200100080A1 (no) |
| EE (1) | EE200000756A (no) |
| ES (1) | ES2184496T3 (no) |
| HR (1) | HRP20000820A2 (no) |
| HU (1) | HUP0102873A3 (no) |
| ID (1) | ID27515A (no) |
| IL (1) | IL139966A0 (no) |
| IS (1) | IS5748A (no) |
| MX (1) | MXPA00012338A (no) |
| NO (1) | NO20006572L (no) |
| NZ (1) | NZ509505A (no) |
| PL (1) | PL345287A1 (no) |
| PT (1) | PT1089761E (no) |
| SK (1) | SK19602000A3 (no) |
| TR (1) | TR200003821T2 (no) |
| WO (1) | WO2000000182A2 (no) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2356262A1 (en) | 1998-12-23 | 2000-07-06 | Jomaa Pharmaka Gmbh | Use of bisphosphonates for the prevention and treatment of infectious processes |
| WO2000038693A1 (fr) * | 1998-12-25 | 2000-07-06 | Toray Industries, Inc. | Inhibiteurs de la production d'interleukine-6 |
| EP1392325B1 (en) * | 2001-05-02 | 2006-06-21 | Novartis AG | Method of administration of bisphosphonates by inhalation in the treatment or prevention of bone resorption and osteoporosis |
| PT1408984E (pt) | 2001-07-20 | 2008-12-26 | Bioagency Ag | Compostos organofosforosos para activar células t gama/delta |
| GB0307989D0 (en) * | 2003-04-07 | 2003-05-14 | Mcewen Lab Ltd | Therapeutic composition |
| EP1713489B1 (en) * | 2004-08-23 | 2011-01-19 | Teva Pharmaceutical Industries Ltd | Crystalline form of ibandronate sodium and processes for preparation thereof |
| EP1931326A4 (en) * | 2005-09-12 | 2009-12-16 | Reddys Lab Ltd Dr | CRYSTALLINE TRIHYDRATE OF ZOLEDONIC ACID |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2114946T3 (es) * | 1991-09-05 | 1998-06-16 | Toray Industries | Derivado de acido metanodifosfonico, su produccion y uso medicinal. |
| WO1996022790A1 (en) * | 1995-01-23 | 1996-08-01 | Xenotech Incorporated | Composition to ameliorate osteolysis and metastasis |
-
1998
- 1998-06-26 DE DE19828450A patent/DE19828450A1/de not_active Withdrawn
-
1999
- 1999-06-24 AT AT99941383T patent/ATE224734T1/de active
- 1999-06-24 EP EP99941383A patent/EP1089761B1/de not_active Expired - Lifetime
- 1999-06-24 EA EA200100080A patent/EA200100080A1/ru unknown
- 1999-06-24 DK DK99941383T patent/DK1089761T3/da active
- 1999-06-24 AU AU55033/99A patent/AU740605B2/en not_active Ceased
- 1999-06-24 JP JP2000556767A patent/JP2002519319A/ja active Pending
- 1999-06-24 WO PCT/DE1999/001844 patent/WO2000000182A2/de not_active Application Discontinuation
- 1999-06-24 HU HU0102873A patent/HUP0102873A3/hu unknown
- 1999-06-24 DE DE59902856T patent/DE59902856D1/de not_active Expired - Lifetime
- 1999-06-24 TR TR2000/03821T patent/TR200003821T2/xx unknown
- 1999-06-24 EE EEP200000756A patent/EE200000756A/xx unknown
- 1999-06-24 CA CA002334711A patent/CA2334711C/en not_active Expired - Fee Related
- 1999-06-24 SK SK1960-2000A patent/SK19602000A3/sk unknown
- 1999-06-24 NZ NZ509505A patent/NZ509505A/xx not_active IP Right Cessation
- 1999-06-24 IL IL13996699A patent/IL139966A0/xx unknown
- 1999-06-24 ES ES99941383T patent/ES2184496T3/es not_active Expired - Lifetime
- 1999-06-24 MX MXPA00012338A patent/MXPA00012338A/es unknown
- 1999-06-24 ID IDW20002676A patent/ID27515A/id unknown
- 1999-06-24 PT PT99941383T patent/PT1089761E/pt unknown
- 1999-06-24 KR KR1020007014813A patent/KR20010053211A/ko not_active Application Discontinuation
- 1999-06-24 PL PL99345287A patent/PL345287A1/xx unknown
-
2000
- 2000-11-29 HR HR20000820A patent/HRP20000820A2/hr not_active Application Discontinuation
- 2000-12-01 IS IS5748A patent/IS5748A/is unknown
- 2000-12-21 NO NO20006572A patent/NO20006572L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE224734T1 (de) | 2002-10-15 |
| KR20010053211A (ko) | 2001-06-25 |
| DE19828450A1 (de) | 1999-12-30 |
| WO2000000182A2 (de) | 2000-01-06 |
| HUP0102873A3 (en) | 2002-04-29 |
| AU740605B2 (en) | 2001-11-08 |
| PL345287A1 (en) | 2001-12-03 |
| TR200003821T2 (tr) | 2001-06-21 |
| DK1089761T3 (da) | 2003-02-03 |
| EA200100080A1 (ru) | 2001-06-25 |
| HRP20000820A2 (en) | 2001-12-31 |
| HUP0102873A2 (hu) | 2001-12-28 |
| NZ509505A (en) | 2002-11-26 |
| CA2334711A1 (en) | 2000-01-06 |
| NO20006572D0 (no) | 2000-12-21 |
| PT1089761E (pt) | 2003-02-28 |
| CA2334711C (en) | 2006-12-05 |
| EP1089761B1 (de) | 2002-09-25 |
| MXPA00012338A (es) | 2003-04-25 |
| EP1089761A2 (de) | 2001-04-11 |
| DE59902856D1 (de) | 2002-10-31 |
| IL139966A0 (en) | 2002-02-10 |
| JP2002519319A (ja) | 2002-07-02 |
| AU5503399A (en) | 2000-01-17 |
| SK19602000A3 (sk) | 2001-07-10 |
| ID27515A (id) | 2001-04-12 |
| IS5748A (is) | 2000-12-01 |
| ES2184496T3 (es) | 2003-04-01 |
| EE200000756A (et) | 2002-04-15 |
| WO2000000182A3 (de) | 2000-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |