NO20006205L - Morfin-6-glukuronidsyntese - Google Patents
Morfin-6-glukuronidsynteseInfo
- Publication number
- NO20006205L NO20006205L NO20006205A NO20006205A NO20006205L NO 20006205 L NO20006205 L NO 20006205L NO 20006205 A NO20006205 A NO 20006205A NO 20006205 A NO20006205 A NO 20006205A NO 20006205 L NO20006205 L NO 20006205L
- Authority
- NO
- Norway
- Prior art keywords
- morphine
- glukuronidsyntese
- pivaloyloxymorphine
- pivaloylglucouronate
- ethylorthopivalate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/127—Preparation from compounds containing pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
- C07H9/04—Cyclic acetals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyridine Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9812097.5A GB9812097D0 (en) | 1998-06-06 | 1998-06-06 | Morphine-6-glucuronide synthesis |
GB9900833 | 1999-01-15 | ||
PCT/GB1999/001777 WO1999064430A2 (en) | 1998-06-06 | 1999-06-04 | Morphine-6-glucuronide synthesis |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20006205L true NO20006205L (no) | 2000-12-06 |
NO20006205D0 NO20006205D0 (no) | 2000-12-06 |
NO316876B1 NO316876B1 (no) | 2004-06-07 |
Family
ID=26313798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20006205A NO316876B1 (no) | 1998-06-06 | 2000-12-06 | Morfin-6-glukuronidsyntese |
Country Status (15)
Country | Link |
---|---|
US (2) | US6566510B1 (no) |
EP (1) | EP1086114B1 (no) |
JP (1) | JP2002517504A (no) |
AT (1) | ATE225363T1 (no) |
AU (1) | AU762800B2 (no) |
CA (1) | CA2332974C (no) |
DE (1) | DE69903291T2 (no) |
DK (1) | DK1086114T3 (no) |
ES (1) | ES2185350T3 (no) |
HU (1) | HUP0102333A3 (no) |
IL (1) | IL139773A0 (no) |
NO (1) | NO316876B1 (no) |
PL (1) | PL194362B1 (no) |
PT (1) | PT1086114E (no) |
WO (1) | WO1999064430A2 (no) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9914382D0 (en) * | 1999-06-21 | 1999-08-18 | Ufc Limited | New process for the manufacture of morphine-6-glucuronide and its analogues and also to a manufacture of new intermediaries |
FR2907121B1 (fr) | 2006-10-12 | 2012-05-04 | Neorphys | Nouveaux derives morphiniques |
FR2939437B1 (fr) | 2008-12-10 | 2010-12-17 | Sanofi Aventis | Derives de morphine-6-glucuronide, leur preparation et leur application en therapeutique |
FR2939436B1 (fr) * | 2008-12-10 | 2010-12-17 | Sanofi Aventis | Synthese de morphine-6-glucuronide ou de l'un de ses derives |
FR2939796B1 (fr) | 2008-12-11 | 2010-12-17 | Sanofi Aventis | Derives bicycliques de morphine-6-glucuronide, leur preparation et leur application en therapeutique |
US20180110725A1 (en) | 2016-10-21 | 2018-04-26 | Somniferum Labs LLC | Compositions, methods and kits for the safe inhaled delivery of targeted opioids for the treatment of pain and addiction |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9116909D0 (en) * | 1991-08-06 | 1991-09-18 | Salford Ultrafine Chem & Res | Morphine derivatives |
GB9325065D0 (en) * | 1993-12-07 | 1994-02-02 | Salford Ultrafine Chem & Res | An enzymatic process for making morphine-6-glucuronide or substituted morphine-6-glucuronide |
FR2680786B1 (fr) | 1991-09-04 | 1995-03-10 | Irepa | Procede de synthese de glucuronides d'epoxy-4,5 morphinanes. |
AU5108596A (en) * | 1995-03-14 | 1996-10-02 | Mundipharma Gmbh | Morphine-3-esters |
DE19508664C2 (de) * | 1995-03-14 | 2001-08-23 | Christian Mignat | Verwendung von Morphin-3-estern, Morphin-3-ester als solche und Verfahren zu deren Herstellung |
-
1999
- 1999-06-04 PT PT99925205T patent/PT1086114E/pt unknown
- 1999-06-04 WO PCT/GB1999/001777 patent/WO1999064430A2/en active IP Right Grant
- 1999-06-04 CA CA002332974A patent/CA2332974C/en not_active Expired - Fee Related
- 1999-06-04 PL PL99345195A patent/PL194362B1/pl not_active IP Right Cessation
- 1999-06-04 HU HU0102333A patent/HUP0102333A3/hu unknown
- 1999-06-04 IL IL13977399A patent/IL139773A0/xx not_active IP Right Cessation
- 1999-06-04 DK DK99925205T patent/DK1086114T3/da active
- 1999-06-04 JP JP2000553438A patent/JP2002517504A/ja active Pending
- 1999-06-04 US US09/700,909 patent/US6566510B1/en not_active Expired - Fee Related
- 1999-06-04 DE DE69903291T patent/DE69903291T2/de not_active Expired - Lifetime
- 1999-06-04 ES ES99925205T patent/ES2185350T3/es not_active Expired - Lifetime
- 1999-06-04 EP EP99925205A patent/EP1086114B1/en not_active Expired - Lifetime
- 1999-06-04 AU AU41584/99A patent/AU762800B2/en not_active Ceased
- 1999-06-04 AT AT99925205T patent/ATE225363T1/de active
-
2000
- 2000-12-06 NO NO20006205A patent/NO316876B1/no not_active IP Right Cessation
-
2002
- 2002-10-04 US US10/263,693 patent/US6693179B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2002517504A (ja) | 2002-06-18 |
DE69903291T2 (de) | 2003-06-26 |
ATE225363T1 (de) | 2002-10-15 |
HUP0102333A3 (en) | 2003-07-28 |
WO1999064430A3 (en) | 2000-02-03 |
CA2332974A1 (en) | 1999-12-16 |
HUP0102333A2 (hu) | 2001-11-28 |
NO316876B1 (no) | 2004-06-07 |
ES2185350T3 (es) | 2003-04-16 |
EP1086114B1 (en) | 2002-10-02 |
DE69903291D1 (en) | 2002-11-07 |
US20030083476A1 (en) | 2003-05-01 |
IL139773A0 (en) | 2002-02-10 |
PL194362B1 (pl) | 2007-05-31 |
PT1086114E (pt) | 2003-02-28 |
AU762800B2 (en) | 2003-07-03 |
WO1999064430A2 (en) | 1999-12-16 |
CA2332974C (en) | 2009-03-10 |
PL345195A1 (en) | 2001-12-03 |
US6566510B1 (en) | 2003-05-20 |
NO20006205D0 (no) | 2000-12-06 |
AU4158499A (en) | 1999-12-30 |
DK1086114T3 (da) | 2003-02-10 |
US6693179B2 (en) | 2004-02-17 |
EP1086114A2 (en) | 2001-03-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |