NO20005625L - Anvendelse av toremifen og dens metabolske analoger, og deres farmasoytisk akseptable salter, estere, N-oksider og blanding av disse, i fremstilling av et farmasoytisk preparat for behandling av prostataintraepitelisk neoplasi (PIN) - Google Patents
Anvendelse av toremifen og dens metabolske analoger, og deres farmasoytisk akseptable salter, estere, N-oksider og blanding av disse, i fremstilling av et farmasoytisk preparat for behandling av prostataintraepitelisk neoplasi (PIN)Info
- Publication number
- NO20005625L NO20005625L NO20005625A NO20005625A NO20005625L NO 20005625 L NO20005625 L NO 20005625L NO 20005625 A NO20005625 A NO 20005625A NO 20005625 A NO20005625 A NO 20005625A NO 20005625 L NO20005625 L NO 20005625L
- Authority
- NO
- Norway
- Prior art keywords
- pin
- intraepithelial neoplasia
- toremifene
- oxides
- esters
- Prior art date
Links
- 208000021046 prostate intraepithelial neoplasia Diseases 0.000 title abstract 3
- 150000001204 N-oxides Chemical class 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000002503 metabolic effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- XFCLJVABOIYOMF-QPLCGJKRSA-N toremifene Chemical compound C1=CC(OCCN(C)C)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 XFCLJVABOIYOMF-QPLCGJKRSA-N 0.000 title 1
- 229960005026 toremifene Drugs 0.000 title 1
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- IWEQQRMGNVVKQW-OQKDUQJOSA-N Toremifene citrate Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O.C1=CC(OCCN(C)C)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 IWEQQRMGNVVKQW-OQKDUQJOSA-N 0.000 abstract 1
- 230000002113 chemopreventative effect Effects 0.000 abstract 1
- 229940124443 chemopreventive agent Drugs 0.000 abstract 1
- 239000012627 chemopreventive agent Substances 0.000 abstract 1
- 229960004167 toremifene citrate Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8460298P | 1998-05-07 | 1998-05-07 | |
| PCT/US1999/010146 WO1999056739A1 (en) | 1998-05-07 | 1999-05-07 | A method for chemoprevention of prostate cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20005625D0 NO20005625D0 (no) | 2000-11-07 |
| NO20005625L true NO20005625L (no) | 2001-01-05 |
Family
ID=22186034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20005625A NO20005625L (no) | 1998-05-07 | 2000-11-07 | Anvendelse av toremifen og dens metabolske analoger, og deres farmasoytisk akseptable salter, estere, N-oksider og blanding av disse, i fremstilling av et farmasoytisk preparat for behandling av prostataintraepitelisk neoplasi (PIN) |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6265448B1 (cs) |
| EP (3) | EP1475087A3 (cs) |
| JP (2) | JP4482229B2 (cs) |
| AT (1) | ATE283043T1 (cs) |
| AU (1) | AU761435B2 (cs) |
| BG (1) | BG65597B1 (cs) |
| CA (1) | CA2323809C (cs) |
| CZ (1) | CZ300960B6 (cs) |
| DE (2) | DE69922131T2 (cs) |
| DK (1) | DK1003496T3 (cs) |
| EA (1) | EA003466B1 (cs) |
| ES (1) | ES2145730T3 (cs) |
| HR (1) | HRP20000729A2 (cs) |
| HU (1) | HUP0102068A3 (cs) |
| IL (3) | IL138437A0 (cs) |
| IS (2) | IS2213B (cs) |
| NO (1) | NO20005625L (cs) |
| NZ (1) | NZ527522A (cs) |
| PL (1) | PL207462B1 (cs) |
| PT (1) | PT1003496E (cs) |
| SI (1) | SI1003496T1 (cs) |
| SK (1) | SK16642000A3 (cs) |
| TR (1) | TR200003269T2 (cs) |
| UA (1) | UA74532C2 (cs) |
| WO (1) | WO1999056739A1 (cs) |
| YU (1) | YU68600A (cs) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040176470A1 (en) * | 1998-05-07 | 2004-09-09 | Steiner Mitchell S. | Method for treatment and chemoprevention of prostate cancer |
| US6413533B1 (en) * | 1998-05-07 | 2002-07-02 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
| US20030130316A1 (en) * | 2000-03-20 | 2003-07-10 | Steiner Mitchell S. | Method for chemoprevention of prostate cancer |
| US6410043B1 (en) * | 1998-05-07 | 2002-06-25 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
| US20040092602A1 (en) * | 1998-05-07 | 2004-05-13 | Steiner Mitchell S. | Method for treatment and chemoprevention of prostate cancer |
| EA003466B1 (ru) * | 1998-05-07 | 2003-06-26 | Те Юниверсити Оф Теннесси Рисерч Корпорейшн | Способ химиопрофилактики рака предстательной железы |
| US6642274B1 (en) | 1999-09-09 | 2003-11-04 | Gary W. Neal | Methods and compositions for preventing and treating prostate disorders |
| WO2001017479A2 (en) * | 1999-09-09 | 2001-03-15 | Androsolutions, Inc. | Methods and compositions for preventing and treating prostate disorders |
| MXPA04005112A (es) | 2001-11-29 | 2005-04-29 | Gtx Inc | Prevencion y tratamiento de osteoporosis inducida por privacion de androgeno. |
| US20040214898A1 (en) * | 2001-11-29 | 2004-10-28 | Steiner Mitchell S. | Methods for treating hot flashes |
| US20040096510A1 (en) * | 2001-11-29 | 2004-05-20 | Steiner Mitchell S. | Prevention and treatment of androgen-deprivation induced osteoporosis |
| US20050080143A1 (en) * | 2001-11-29 | 2005-04-14 | Steiner Mitchell S. | Treatment of androgen-deprivation induced osteoporosis |
| US20070197664A1 (en) * | 2001-11-29 | 2007-08-23 | Steiner Mitchell S | Prevention and treatment of androgen-deprivation induced osteoporosis |
| US7524866B2 (en) * | 2001-11-29 | 2009-04-28 | Gtx, Inc. | Prevention and treatment of androgen—deprivation induced osteoporosis |
| US20080249183A1 (en) * | 2001-11-29 | 2008-10-09 | Steiner Mitchell S | Treatment of androgen-deprivation induced osteoporosis |
| US20060269611A1 (en) * | 2001-11-29 | 2006-11-30 | Steiner Mitchell S | Prevention and treatment of androgen-deprivation induced osteoporosis |
| US20040213841A1 (en) * | 2001-11-29 | 2004-10-28 | Steiner Mitchell S | Methods for treating hot flashes and gynecomastia |
| US7332525B2 (en) * | 2003-01-17 | 2008-02-19 | Castle Erik P | Method of treatment of prostate cancer and composition for treatment thereof |
| US7070816B2 (en) * | 2003-12-05 | 2006-07-04 | New Chapter, Inc. | Methods for treating prostatic intraepithelial neoplasia with herbal compositions |
| US20050208159A1 (en) * | 2004-03-16 | 2005-09-22 | Kang Kyung S | Phytoestrogenic composition comprising an extract of chinese licorice root, liquiritin or isoliquiritin |
| US20060019989A1 (en) * | 2004-07-21 | 2006-01-26 | Steiner Mitchell S | Compositions comprising 5-alpha reductase inhibitors and SERMs and methods of use thereof |
| US20060105045A1 (en) * | 2004-11-08 | 2006-05-18 | Buchanan Charles M | Cyclodextrin solubilizers for liquid and semi-solid formulations |
| WO2006052922A2 (en) * | 2004-11-08 | 2006-05-18 | Eastman Chemical Company | Pharmaceutical formulations of cyclodextrins and selective estrogen receptor modulator compounds |
| US20060270641A1 (en) * | 2005-05-31 | 2006-11-30 | Steiner Mitchell S | Method for chemoprevention of prostate cancer |
| USD969722S1 (en) | 2021-09-28 | 2022-11-15 | Wagner Delima | Stabilizing wedge pad |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4329364A (en) | 1974-09-11 | 1982-05-11 | Schering Corporation | Antiandrogenic agents and methods for the treatment of androgen dependent disease states |
| US4474813A (en) | 1980-10-24 | 1984-10-02 | Schering Corporation | Pharmaceutical preparations comprising flutamide |
| GB2126576B (en) * | 1982-06-25 | 1985-06-19 | Farmos Group Limited | Alkane and alkene derivatives |
| FI77839C (fi) * | 1982-05-27 | 1989-05-10 | Farmos Oy | Foerfarande foer framstaellning av nya terapeutiskt effektiva trifenylalkan- och alkenderivat. |
| US5491173A (en) | 1982-06-25 | 1996-02-13 | Orion-Yhtyma Oy | Tri-phenyl alkene derivatives and their preparation and use |
| US5595985A (en) | 1989-03-10 | 1997-01-21 | Endorecherche Inc. | Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia |
| US4990538A (en) | 1989-08-23 | 1991-02-05 | Harris Adrian L | Use of toremifene and its metabolites for the reversal of multidrug resistance of cancer cells against cytotoxic drugs |
| GB9126209D0 (en) | 1991-12-10 | 1992-02-12 | Orion Yhtymae Oy | Drug formulations for parenteral use |
| GB9207437D0 (en) | 1992-04-03 | 1992-05-20 | Orion Yhtymae Oy | Topical administration of toremifene and its metabolites |
| CA2150714C (en) * | 1992-12-01 | 2002-02-05 | Anni Maija Warri | Syndecan stimulation of cellular differentiation |
| US5595722A (en) | 1993-01-28 | 1997-01-21 | Neorx Corporation | Method for identifying an agent which increases TGF-beta levels |
| JPH08510451A (ja) | 1993-05-13 | 1996-11-05 | ネオルックス コーポレイション | 異常増殖性平滑筋細胞に関連した病因の予防及び治療 |
| HUT74425A (en) | 1993-08-09 | 1996-12-30 | Baral | A method for sensitization of cancer for killer cell mediated lysis |
| US5650425A (en) * | 1994-04-04 | 1997-07-22 | Pharmos Corporation | Permanently ionic derivatives of steroid hormones and their antagonists |
| US5629007A (en) | 1995-03-21 | 1997-05-13 | Eli Lilly And Company | Method of preventing prostatic cancer development |
| US5635197A (en) | 1995-03-21 | 1997-06-03 | Eli Lilly And Company | Treatment and prevention of prostatic cancer metastasis |
| ZA984650B (en) * | 1997-06-19 | 1998-12-08 | Orion Corp | Intratumoral administration of triphenylethylenes for the treatment of cancer |
| EA003466B1 (ru) * | 1998-05-07 | 2003-06-26 | Те Юниверсити Оф Теннесси Рисерч Корпорейшн | Способ химиопрофилактики рака предстательной железы |
-
1999
- 1999-05-07 EA EA200000100A patent/EA003466B1/ru not_active IP Right Cessation
- 1999-05-07 CZ CZ20004118A patent/CZ300960B6/cs not_active IP Right Cessation
- 1999-05-07 DE DE69922131T patent/DE69922131T2/de not_active Expired - Lifetime
- 1999-05-07 WO PCT/US1999/010146 patent/WO1999056739A1/en not_active Ceased
- 1999-05-07 DK DK99924157T patent/DK1003496T3/da active
- 1999-05-07 EP EP04018861A patent/EP1475087A3/en not_active Withdrawn
- 1999-05-07 US US09/306,958 patent/US6265448B1/en not_active Expired - Fee Related
- 1999-05-07 TR TR2000/03269T patent/TR200003269T2/xx unknown
- 1999-05-07 AT AT99924157T patent/ATE283043T1/de not_active IP Right Cessation
- 1999-05-07 HU HU0102068A patent/HUP0102068A3/hu unknown
- 1999-05-07 SI SI9930740T patent/SI1003496T1/xx unknown
- 1999-05-07 CA CA002323809A patent/CA2323809C/en not_active Expired - Fee Related
- 1999-05-07 JP JP2000546766A patent/JP4482229B2/ja not_active Expired - Lifetime
- 1999-05-07 PT PT99924157T patent/PT1003496E/pt unknown
- 1999-05-07 YU YU68600A patent/YU68600A/sh unknown
- 1999-05-07 ES ES99924157T patent/ES2145730T3/es not_active Expired - Lifetime
- 1999-05-07 HR HR20000729A patent/HRP20000729A2/hr not_active Application Discontinuation
- 1999-05-07 IL IL13843799A patent/IL138437A0/xx unknown
- 1999-05-07 EP EP10012242A patent/EP2277514A1/en not_active Withdrawn
- 1999-05-07 AU AU40726/99A patent/AU761435B2/en not_active Ceased
- 1999-05-07 EP EP99924157A patent/EP1003496B1/en not_active Expired - Lifetime
- 1999-05-07 PL PL344000A patent/PL207462B1/pl not_active IP Right Cessation
- 1999-05-07 NZ NZ527522A patent/NZ527522A/xx unknown
- 1999-05-07 DE DE1003496T patent/DE1003496T1/de active Pending
- 1999-05-07 SK SK1664-2000A patent/SK16642000A3/sk unknown
- 1999-07-05 UA UA2000116229A patent/UA74532C2/uk unknown
-
2000
- 2000-09-12 IL IL138437A patent/IL138437A/en not_active IP Right Cessation
- 2000-11-01 IS IS5700A patent/IS2213B/is unknown
- 2000-11-07 NO NO20005625A patent/NO20005625L/no not_active Application Discontinuation
- 2000-12-05 BG BG105022A patent/BG65597B1/bg unknown
-
2006
- 2006-03-15 IS IS8354A patent/IS8354A/is unknown
-
2008
- 2008-03-21 JP JP2008074318A patent/JP2008163048A/ja active Pending
- 2008-08-04 IL IL193231A patent/IL193231A0/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application | ||
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |