NO20004881L - Pyrrolo[1,2-a]pyrazin sPLA2 inhibitor - Google Patents
Pyrrolo[1,2-a]pyrazin sPLA2 inhibitorInfo
- Publication number
- NO20004881L NO20004881L NO20004881A NO20004881A NO20004881L NO 20004881 L NO20004881 L NO 20004881L NO 20004881 A NO20004881 A NO 20004881A NO 20004881 A NO20004881 A NO 20004881A NO 20004881 L NO20004881 L NO 20004881L
- Authority
- NO
- Norway
- Prior art keywords
- pyrrolo
- pyrazine
- atoms
- similar
- group
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8599798 | 1998-03-31 | ||
| JP24473598 | 1998-08-31 | ||
| PCT/JP1999/001670 WO1999051605A1 (en) | 1998-03-31 | 1999-03-31 | PYRROLO[1,2-a]PYRAZINE sPLA2 INHIBITOR |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20004881D0 NO20004881D0 (no) | 2000-09-28 |
| NO20004881L true NO20004881L (no) | 2000-11-28 |
Family
ID=26427020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20004881A NO20004881L (no) | 1998-03-31 | 2000-09-28 | Pyrrolo[1,2-a]pyrazin sPLA2 inhibitor |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6407104B1 (hu) |
| EP (1) | EP1066290A1 (hu) |
| JP (1) | JP4412521B2 (hu) |
| KR (1) | KR20010042307A (hu) |
| CN (1) | CN1303384A (hu) |
| AU (1) | AU3054399A (hu) |
| BR (1) | BR9909345A (hu) |
| CA (1) | CA2326522A1 (hu) |
| HU (1) | HUP0102981A3 (hu) |
| NO (1) | NO20004881L (hu) |
| WO (1) | WO1999051605A1 (hu) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000021563A1 (fr) * | 1998-10-14 | 2000-04-20 | Shionogi & Co., Ltd. | Moyens de traitement et de prevention contre les troubles ischemiques dus a la repercussion |
| WO2001005789A1 (fr) | 1999-07-19 | 2001-01-25 | Shionogi & Co., Ltd. | Composes tricycliques a action inhibitrice a l'encontre de spla¿2? |
| AU6473600A (en) | 1999-08-23 | 2001-03-19 | Shionogi & Co., Ltd. | Pyrrolotriazine derivatives having spla2-inhibitory activities |
| WO2001026653A1 (fr) * | 1999-10-15 | 2001-04-19 | Shionogi & Co., Ltd. | Inhibiteurs spla2 du type v et/ou du type x |
| AU1304801A (en) | 1999-11-15 | 2001-05-30 | Shionogi & Co., Ltd. | Tricyclic azaindolizine derivatives having an SPLA2- inhibiting effect |
| AU2001267823A1 (en) * | 2000-06-29 | 2002-01-08 | Shionogi And Co., Ltd. | Compounds exhibiting x-type spla2 inhibiting effect |
| AU2001267825A1 (en) | 2000-06-29 | 2002-01-08 | Shionogi And Co., Ltd. | Remedies for cirrhosis |
| AUPQ876400A0 (en) * | 2000-07-14 | 2000-08-03 | University Of Queensland, The | Compositions and method of using them |
| JP2004505982A (ja) * | 2000-08-04 | 2004-02-26 | イーライ・リリー・アンド・カンパニー | 新規なｓＰＬＡ２インヒビター |
| TWI314457B (hu) | 2001-03-19 | 2009-09-11 | Shionogi & Co | |
| US6730694B1 (en) | 2001-07-20 | 2004-05-04 | Eli Lilly And Company | sPLA2 inhibitors |
| DE10155727A1 (de) * | 2001-11-13 | 2003-05-28 | Morphochem Ag | Serin Protease Inhibitoren |
| AUPS282602A0 (en) | 2002-06-07 | 2002-06-27 | Garvan Institute Of Medical Research | Method of inhibiting cell proliferation |
| CA2617557A1 (en) * | 2005-08-04 | 2007-02-15 | Sirtris Pharmaceuticals, Inc. | Benzimidazole derivatives as sirtuin modulators |
| TW200916472A (en) * | 2007-06-20 | 2009-04-16 | Sirtris Pharmaceuticals Inc | Sirtuin modulating compounds |
| RU2624506C2 (ru) | 2009-04-29 | 2017-07-04 | АМАРИН КОРПОРЕЙШН ПиЭлСи | Фармацевтические композиции, содержащие ера и сердечно-сосудистое средство, и способы их применения |
| CN105622616A (zh) * | 2016-02-25 | 2016-06-01 | 上海雅本化学有限公司 | 一种4-氯吡咯并嘧啶的制备方法 |
| JPWO2023042716A1 (hu) * | 2021-09-17 | 2023-03-23 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL109311A0 (en) | 1993-04-16 | 1994-07-31 | Lilly Co Eli | 1H-indole-3-acetamide sPla2 inhibitors |
| IL109309A (en) | 1993-04-16 | 2000-06-29 | Lilly Co Eli | 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them |
| ES2377223T3 (es) | 1994-04-01 | 2012-03-23 | Eli Lilly And Company | Éster metÃlico de ácido [[3-(2-amino-1,2-dioxoetil)-2-etil-1-(fenilmetil)-11H-indol-4-IL]oxi]acético como inhibidor de sPLA2 |
| JPH10505584A (ja) * | 1994-07-21 | 1998-06-02 | イーライ・リリー・アンド・カンパニー | インドリジンｓＰＬＡ▲下２▼インヒビター |
| US6214876B1 (en) * | 1994-07-21 | 2001-04-10 | Eli Lilly And Company | Indene-1-acetamide sPLA2 inhibitors |
| US5641800A (en) | 1994-07-21 | 1997-06-24 | Eli Lilly And Company | 1H-indole-1-functional sPLA2 inhibitors |
| HUP9902120A3 (en) | 1995-12-13 | 1999-12-28 | Lilly Co Eli | Naphthyl glyoxamides as spla2 inhibitors |
| PT779271E (pt) | 1995-12-13 | 2001-11-30 | Lilly Co Eli | Naftilacetamidas como inibidores da spla2 |
| WO1998018464A1 (en) | 1996-10-30 | 1998-05-07 | Eli Lilly And Company | Substituted tricyclics |
| US5916922A (en) | 1996-12-03 | 1999-06-29 | Eli Lilly And Company | Phenyl glyoxamides as SPLA2 inhibitors |
| US6353128B1 (en) | 1996-12-03 | 2002-03-05 | Eli Lilly And Company | Phenyl acetamides as sPLA2 inhibitors |
| ID18983A (id) | 1996-12-04 | 1998-05-28 | Lilly Co Eli | Pirazola sebagai inhibitor sekresi fosfolipase a2 non-pankreas pada manusia |
| US5919774A (en) | 1996-12-10 | 1999-07-06 | Eli Lilly And Company | Pyrroles as sPLA2 inhibitors |
| TW455581B (en) | 1997-06-26 | 2001-09-21 | Lilly Co Eli | Process for preparing 4-substituted-1H-indole-3-glyoxamides |
-
1999
- 1999-03-31 WO PCT/JP1999/001670 patent/WO1999051605A1/en not_active Application Discontinuation
- 1999-03-31 KR KR1020007010855A patent/KR20010042307A/ko not_active Application Discontinuation
- 1999-03-31 EP EP99912066A patent/EP1066290A1/en not_active Ceased
- 1999-03-31 HU HU0102981A patent/HUP0102981A3/hu unknown
- 1999-03-31 CN CN99806627A patent/CN1303384A/zh active Pending
- 1999-03-31 CA CA002326522A patent/CA2326522A1/en not_active Abandoned
- 1999-03-31 JP JP2000542326A patent/JP4412521B2/ja not_active Expired - Fee Related
- 1999-03-31 US US09/623,591 patent/US6407104B1/en not_active Expired - Fee Related
- 1999-03-31 AU AU30543/99A patent/AU3054399A/en not_active Abandoned
- 1999-03-31 BR BR9909345-6A patent/BR9909345A/pt not_active IP Right Cessation
-
2000
- 2000-09-28 NO NO20004881A patent/NO20004881L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0102981A3 (en) | 2002-10-28 |
| CN1303384A (zh) | 2001-07-11 |
| AU3054399A (en) | 1999-10-25 |
| JP4412521B2 (ja) | 2010-02-10 |
| JP2002530268A (ja) | 2002-09-17 |
| BR9909345A (pt) | 2000-12-12 |
| CA2326522A1 (en) | 1999-10-14 |
| US6407104B1 (en) | 2002-06-18 |
| NO20004881D0 (no) | 2000-09-28 |
| WO1999051605A1 (en) | 1999-10-14 |
| HUP0102981A2 (hu) | 2002-01-28 |
| KR20010042307A (ko) | 2001-05-25 |
| EP1066290A1 (en) | 2001-01-10 |
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