NO20004044L - Streptomyces Avertimilis gene that controls the ratio of B2: B1 avermectins - Google Patents

Streptomyces Avertimilis gene that controls the ratio of B2: B1 avermectins

Info

Publication number
NO20004044L
NO20004044L NO20004044A NO20004044A NO20004044L NO 20004044 L NO20004044 L NO 20004044L NO 20004044 A NO20004044 A NO 20004044A NO 20004044 A NO20004044 A NO 20004044A NO 20004044 L NO20004044 L NO 20004044L
Authority
NO
Norway
Prior art keywords
avertimilis
avermectins
streptomyces
gene
controls
Prior art date
Application number
NO20004044A
Other languages
Norwegian (no)
Other versions
NO20004044D0 (en
Inventor
Kim Jonelle Stutzman-Engwall
Yoshihiro Katoh
Hamish Alastair Irvin Mcarthur
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20004044D0 publication Critical patent/NO20004044D0/en
Publication of NO20004044L publication Critical patent/NO20004044L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
NO20004044A 1998-02-13 2000-08-11 Streptomyces Avertimilis gene that controls the ratio of B2: B1 avermectins NO20004044L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7463698P 1998-02-13 1998-02-13
PCT/IB1999/000130 WO1999041389A1 (en) 1998-02-13 1999-01-25 Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins

Publications (2)

Publication Number Publication Date
NO20004044D0 NO20004044D0 (en) 2000-08-11
NO20004044L true NO20004044L (en) 2000-10-11

Family

ID=22120706

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004044A NO20004044L (en) 1998-02-13 2000-08-11 Streptomyces Avertimilis gene that controls the ratio of B2: B1 avermectins

Country Status (32)

Country Link
EP (1) EP1053335A1 (en)
JP (2) JP2002503473A (en)
KR (3) KR100499214B1 (en)
CN (2) CN1521180A (en)
AP (1) AP9901463A0 (en)
AR (1) AR018085A1 (en)
AU (1) AU752343C (en)
BG (1) BG64911B1 (en)
BR (1) BR9907893A (en)
CA (2) CA2521289A1 (en)
CO (1) CO5070698A1 (en)
DZ (1) DZ2720A1 (en)
EA (1) EA003905B1 (en)
GT (1) GT199900014A (en)
HN (1) HN1999000008A (en)
HR (1) HRP20000539A2 (en)
HU (1) HUP0100784A3 (en)
IL (2) IL137610A0 (en)
IS (1) IS5567A (en)
MA (1) MA24760A1 (en)
NO (1) NO20004044L (en)
NZ (2) NZ518657A (en)
OA (1) OA11449A (en)
PA (1) PA8467601A1 (en)
PE (1) PE20000352A1 (en)
PL (1) PL194270B1 (en)
SK (1) SK11722000A3 (en)
TN (1) TNSN99017A1 (en)
TW (1) TW585910B (en)
WO (1) WO1999041389A1 (en)
YU (1) YU50900A (en)
ZA (1) ZA991138B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6248579B1 (en) * 1998-02-13 2001-06-19 Pfizer Inc Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins
EP1053335A1 (en) * 1998-02-13 2000-11-22 Pfizer Products Inc. Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins
CA2380872C (en) * 1999-08-12 2007-11-27 Yan Chen Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins
US7630836B2 (en) 2001-05-30 2009-12-08 The Kitasato Institute Polynucleotides
ATE426659T1 (en) 2002-02-12 2009-04-15 Pfizer Prod Inc STREPTOMYCES AVERMITILIS GENE REGULATING THE B2:B1 AVERMECTINE RATIO
CN107338210B (en) * 2017-09-05 2021-08-17 天津科技大学 Abamectin streptomycete synthetic medium and preparation method of fermentation liquor thereof
CN111269296B (en) * 2020-03-06 2021-11-05 山东大学 nLsA protein, structural gene thereof and application thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (en) * 1976-04-19 1984-07-16 Merck & Co Inc SET TO MAKE NEW ANTIHELMINTICALLY EFFECTIVE ASSOCIATIONS BY CULTIVATING STREPTOMYCS AVERMITILIS
US4429042A (en) * 1978-09-08 1984-01-31 Merck & Co., Inc. Strain of Streptomyces for producing antiparasitic compounds
IN167980B (en) * 1987-01-23 1991-01-19 Pfizer
DE3881147T2 (en) * 1987-10-23 1993-09-02 Pfizer METHOD FOR PRODUCING AGLYCONES OF AVERMECTIN AND CULTURES CONTAINING THEM.
JPH0747171B2 (en) * 1988-09-20 1995-05-24 株式会社東芝 Rolling mill setting method and device
US5252474A (en) * 1989-03-31 1993-10-12 Merck & Co., Inc. Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use
NZ233116A (en) * 1989-03-31 1994-09-27 Merck & Co Inc Cloning genes from steptomyces avermitilis for avermectin biosynthesis
JP2888586B2 (en) * 1990-03-05 1999-05-10 社団法人北里研究所 Microorganism for selective production of specific components of avermectin and its selective production method
FI942725A (en) * 1993-12-16 1995-06-17 Pfizer Genes encoding branched chain alpha-keto acid dehydrogenase complex from Streptomyces avermitilis
EP1053335A1 (en) * 1998-02-13 2000-11-22 Pfizer Products Inc. Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins

Also Published As

Publication number Publication date
EA200000758A1 (en) 2001-04-23
DZ2720A1 (en) 2003-09-01
CN1521180A (en) 2004-08-18
AR018085A1 (en) 2001-10-31
KR20040053390A (en) 2004-06-23
AP9901463A0 (en) 1999-03-31
CA2521289A1 (en) 1999-08-19
PL194270B1 (en) 2007-05-31
NZ505676A (en) 2003-02-28
KR20040099389A (en) 2004-11-26
AU1887899A (en) 1999-08-30
KR100499214B1 (en) 2005-07-07
TW585910B (en) 2004-05-01
CA2320031A1 (en) 1999-08-19
GT199900014A (en) 2000-07-25
CN1297485A (en) 2001-05-30
NO20004044D0 (en) 2000-08-11
JP4011036B2 (en) 2007-11-21
MA24760A1 (en) 1999-10-01
HN1999000008A (en) 1999-10-29
PA8467601A1 (en) 2000-09-29
JP2004283174A (en) 2004-10-14
JP2002503473A (en) 2002-02-05
BG64911B1 (en) 2006-08-31
IL183596A0 (en) 2007-09-20
WO1999041389A1 (en) 1999-08-19
IS5567A (en) 2000-07-20
PE20000352A1 (en) 2000-05-16
TNSN99017A1 (en) 2005-11-10
IL137610A0 (en) 2001-07-24
AU752343B2 (en) 2002-09-19
ZA991138B (en) 2000-08-14
BR9907893A (en) 2000-11-14
EA003905B1 (en) 2003-10-30
SK11722000A3 (en) 2001-04-09
OA11449A (en) 2003-12-03
BG104759A (en) 2001-04-30
YU50900A (en) 2004-03-12
HUP0100784A2 (en) 2001-06-28
HRP20000539A2 (en) 2001-04-30
CO5070698A1 (en) 2001-08-28
HUP0100784A3 (en) 2004-10-28
AU752343C (en) 2005-11-03
EP1053335A1 (en) 2000-11-22
PL342468A1 (en) 2001-06-04
KR20010052166A (en) 2001-06-25
NZ518657A (en) 2003-10-31

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