GT199900014A - STREPTOMYCES AVERMILITIS GENE THAT DIRECTS THE AVERMECTIN RELATION B2: B1. - Google Patents
STREPTOMYCES AVERMILITIS GENE THAT DIRECTS THE AVERMECTIN RELATION B2: B1.Info
- Publication number
- GT199900014A GT199900014A GT199900014A GT199900014A GT199900014A GT 199900014 A GT199900014 A GT 199900014A GT 199900014 A GT199900014 A GT 199900014A GT 199900014 A GT199900014 A GT 199900014A GT 199900014 A GT199900014 A GT 199900014A
- Authority
- GT
- Guatemala
- Prior art keywords
- gene
- avermilitis
- avermectin
- streptomyces
- directs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
Abstract
LA PRESENTE INVENCION SE REFIERE A MOLECULAS POLINUCLEOTIDICAS QUE COMPRENDEN SECUENCIAS DE NUCLEOTIDOS QUE CODIFICAN UN PRODUCTO GENICO AVEC, MOLECULAS POLINUCLEOTIDICAS QUE PUEDEN USARSE PARA ALTERAR LA RELACION O CANTIDAD DE AVERMECTINAS DE CLASES 2 : 1 PRODUCIDAS EN CULTIVOS DE FERMENTACION DE S. AVERMITILIS. LA PRESENTE INVENCION SE REFIERE ADEMAS A VECTORES, CELULAS HOSPEDADORAS Y CEPAS MUTANTES DE S. AVERMITILIS EN LAS QUE EL GEN AVEC SE HA INACTIVADO O MUTADO PARA CAMBIAR LA RELACION O CANTIDAD DE AVERMECTINAS DE CLASES 2 : 1 PRODUCIDAS.THE PRESENT INVENTION REFERS TO POLYNUCLEOTIDIC MOLECULES WHICH INCLUDE NUCLEOTIDE SEQUENCES CODING A GENETIC PRODUCT AVEC, POLYNUCLEOTIDIC MOLECULES THAT MAY BE USED TO ALTER THE DEVELOPMENT OF THE 2-DEPARTMENT OF AVERMECTS OF CLAS THE PRESENT INVENTION FURTHER REFERS TO VECTORS, HOSPITAL CELLS AND MUTANT STRAINS OF S. AVERMITILIS IN WHICH THE AVEC GENE HAS BEEN INACTIVATED OR MUTED TO CHANGE THE RATIO OR NUMBER OF CLASS 2: 1 PRODUCTS PRODUCED.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7463698P | 1998-02-13 | 1998-02-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT199900014A true GT199900014A (en) | 2000-07-25 |
Family
ID=22120706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT199900014A GT199900014A (en) | 1998-02-13 | 1999-02-01 | STREPTOMYCES AVERMILITIS GENE THAT DIRECTS THE AVERMECTIN RELATION B2: B1. |
Country Status (32)
| Country | Link |
|---|---|
| EP (1) | EP1053335A1 (en) |
| JP (2) | JP2002503473A (en) |
| KR (3) | KR20040099389A (en) |
| CN (2) | CN1297485A (en) |
| AP (1) | AP9901463A0 (en) |
| AR (1) | AR018085A1 (en) |
| AU (1) | AU752343C (en) |
| BG (1) | BG64911B1 (en) |
| BR (1) | BR9907893A (en) |
| CA (2) | CA2320031A1 (en) |
| CO (1) | CO5070698A1 (en) |
| DZ (1) | DZ2720A1 (en) |
| EA (1) | EA003905B1 (en) |
| GT (1) | GT199900014A (en) |
| HN (1) | HN1999000008A (en) |
| HR (1) | HRP20000539A2 (en) |
| HU (1) | HUP0100784A3 (en) |
| IL (2) | IL137610A0 (en) |
| IS (1) | IS5567A (en) |
| MA (1) | MA24760A1 (en) |
| NO (1) | NO20004044L (en) |
| NZ (2) | NZ518657A (en) |
| OA (1) | OA11449A (en) |
| PA (1) | PA8467601A1 (en) |
| PE (1) | PE20000352A1 (en) |
| PL (1) | PL194270B1 (en) |
| SK (1) | SK11722000A3 (en) |
| TN (1) | TNSN99017A1 (en) |
| TW (1) | TW585910B (en) |
| WO (1) | WO1999041389A1 (en) |
| YU (1) | YU50900A (en) |
| ZA (1) | ZA991138B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ518657A (en) * | 1998-02-13 | 2003-10-31 | Pfizer Prod Inc | Streptomyces hygroscopicus directing the ratio of B2:B1 avermectins |
| US6248579B1 (en) * | 1998-02-13 | 2001-06-19 | Pfizer Inc | Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins |
| KR100489856B1 (en) * | 1999-08-12 | 2005-05-17 | 화이자 프로덕츠 인코포레이티드 | Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins |
| US7630836B2 (en) | 2001-05-30 | 2009-12-08 | The Kitasato Institute | Polynucleotides |
| MXPA04007777A (en) * | 2002-02-12 | 2004-10-15 | Pfizer Prod Inc | Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins. |
| CN107338210B (en) * | 2017-09-05 | 2021-08-17 | 天津科技大学 | Abamectin streptomycete synthetic medium and preparation method of fermentation liquor thereof |
| CN111269296B (en) * | 2020-03-06 | 2021-11-05 | 山东大学 | nLsA protein, structural gene thereof and application thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE434277B (en) * | 1976-04-19 | 1984-07-16 | Merck & Co Inc | SET TO MAKE NEW ANTIHELMINTICALLY EFFECTIVE ASSOCIATIONS BY CULTIVATING STREPTOMYCS AVERMITILIS |
| US4429042A (en) * | 1978-09-08 | 1984-01-31 | Merck & Co., Inc. | Strain of Streptomyces for producing antiparasitic compounds |
| IN167980B (en) * | 1987-01-23 | 1991-01-19 | Pfizer | |
| ATE89604T1 (en) * | 1987-10-23 | 1993-06-15 | Pfizer | PROCESS FOR THE PREPARATION OF AGLYCONES OF AVERMECTIN AND CULTURES CONTAINING THEM. |
| JPH0747171B2 (en) * | 1988-09-20 | 1995-05-24 | 株式会社東芝 | Rolling mill setting method and device |
| US5252474A (en) * | 1989-03-31 | 1993-10-12 | Merck & Co., Inc. | Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
| DE69023036T2 (en) * | 1989-03-31 | 1996-06-13 | Merck & Co Inc | Cloning of Streptomyces avermitilis genes for the biosynthesis of avermectin and method of using them. |
| JP2888586B2 (en) * | 1990-03-05 | 1999-05-10 | 社団法人北里研究所 | Microorganism for selective production of specific components of avermectin and its selective production method |
| FI942725A (en) * | 1993-12-16 | 1995-06-17 | Pfizer | Genes encoding branched chain alpha-keto acid dehydrogenase complex from Streptomyces avermitilis |
| NZ518657A (en) * | 1998-02-13 | 2003-10-31 | Pfizer Prod Inc | Streptomyces hygroscopicus directing the ratio of B2:B1 avermectins |
-
1999
- 1999-01-25 NZ NZ518657A patent/NZ518657A/en unknown
- 1999-01-25 CA CA002320031A patent/CA2320031A1/en not_active Abandoned
- 1999-01-25 SK SK1172-2000A patent/SK11722000A3/en unknown
- 1999-01-25 BR BR9907893-7A patent/BR9907893A/en not_active Application Discontinuation
- 1999-01-25 EP EP99900270A patent/EP1053335A1/en not_active Withdrawn
- 1999-01-25 NZ NZ505676A patent/NZ505676A/en unknown
- 1999-01-25 HU HU0100784A patent/HUP0100784A3/en not_active Application Discontinuation
- 1999-01-25 WO PCT/IB1999/000130 patent/WO1999041389A1/en not_active Application Discontinuation
- 1999-01-25 CN CN99805027A patent/CN1297485A/en active Pending
- 1999-01-25 KR KR10-2004-7015691A patent/KR20040099389A/en active Search and Examination
- 1999-01-25 KR KR10-2004-7008310A patent/KR20040053390A/en active Search and Examination
- 1999-01-25 EA EA200000758A patent/EA003905B1/en not_active IP Right Cessation
- 1999-01-25 IL IL13761099A patent/IL137610A0/en unknown
- 1999-01-25 KR KR10-2000-7008870A patent/KR100499214B1/en not_active IP Right Cessation
- 1999-01-25 CN CNA2004100054154A patent/CN1521180A/en active Pending
- 1999-01-25 AU AU18878/99A patent/AU752343C/en not_active Ceased
- 1999-01-25 YU YU50900A patent/YU50900A/en unknown
- 1999-01-25 JP JP2000531570A patent/JP2002503473A/en active Pending
- 1999-01-25 CA CA002521289A patent/CA2521289A1/en not_active Abandoned
- 1999-01-25 PL PL99342468A patent/PL194270B1/en not_active IP Right Cessation
- 1999-01-26 PA PA19998467601A patent/PA8467601A1/en unknown
- 1999-02-01 GT GT199900014A patent/GT199900014A/en unknown
- 1999-02-05 HN HN1991000008A patent/HN1999000008A/en unknown
- 1999-02-08 PE PE1999000099A patent/PE20000352A1/en not_active Application Discontinuation
- 1999-02-09 TW TW088102005A patent/TW585910B/en active
- 1999-02-10 DZ DZ990021A patent/DZ2720A1/en active
- 1999-02-10 TN TNTNSN99017A patent/TNSN99017A1/en unknown
- 1999-02-10 MA MA25460A patent/MA24760A1/en unknown
- 1999-02-11 AP APAP/P/1999/001463A patent/AP9901463A0/en unknown
- 1999-02-11 AR ARP990100571A patent/AR018085A1/en unknown
- 1999-02-12 CO CO99008652A patent/CO5070698A1/en unknown
- 1999-02-12 ZA ZA9901138A patent/ZA991138B/en unknown
-
2000
- 2000-07-20 IS IS5567A patent/IS5567A/en unknown
- 2000-08-04 OA OA1200000217A patent/OA11449A/en unknown
- 2000-08-11 HR HR20000539A patent/HRP20000539A2/en not_active Application Discontinuation
- 2000-08-11 NO NO20004044A patent/NO20004044L/en not_active Application Discontinuation
- 2000-09-12 BG BG104759A patent/BG64911B1/en unknown
-
2004
- 2004-04-27 JP JP2004130624A patent/JP4011036B2/en not_active Expired - Fee Related
-
2007
- 2007-05-31 IL IL183596A patent/IL183596A0/en unknown
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