NO20003206L - Polyetoksylert ricinusolje, samt fremgangsmÕte til fremstilling av samme - Google Patents
Polyetoksylert ricinusolje, samt fremgangsmÕte til fremstilling av sammeInfo
- Publication number
- NO20003206L NO20003206L NO20003206A NO20003206A NO20003206L NO 20003206 L NO20003206 L NO 20003206L NO 20003206 A NO20003206 A NO 20003206A NO 20003206 A NO20003206 A NO 20003206A NO 20003206 L NO20003206 L NO 20003206L
- Authority
- NO
- Norway
- Prior art keywords
- polyethoxylated castor
- castor oil
- cationic
- making
- well
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C07C67/56—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Fats And Perfumes (AREA)
- Polyethers (AREA)
Abstract
Det beskrives polyetoksylert ricinusolje med et lavt kationinnhold, sammen med bestemte fremgangsmåter for å oppnå polyetoksylert ricinusolje med et slikt lavt kation- innhold. En fremgangsmåte for framstilling av en slik poly- etoksylert ricinusolje med lavt kationinnhold i samsvar med oppfinnelsen er å forbehandle polyetoksylert ricinusolje med en sterk kationisk utbytteharpiks for å fjerne en vesentlig andel av kationene som foreligger i en ikke- behandlet polyetoksylert ricinusolje. Den polyetoksylerte ricinusolje med lavt kationinnhold ifølge oppfinnelsen kan deretter anvendes for å framstille formuleringer av for- skjellige midler som finnes å være sensitive til tidligere kommersielt tilgjengelige polyetoksylerte ricinusoljer (CREMOPHOR EL®).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/998,306 US5925776A (en) | 1997-12-24 | 1997-12-24 | Polyethoxylated castor oil, process of making the same and formulations thereof |
PCT/US1998/008521 WO1999033780A1 (en) | 1997-12-24 | 1998-04-28 | Novel polyethoxylated castor oil, process of making the same and formulations thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20003206D0 NO20003206D0 (no) | 2000-06-21 |
NO20003206L true NO20003206L (no) | 2000-08-22 |
Family
ID=25545031
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20003206A NO20003206L (no) | 1997-12-24 | 2000-06-21 | Polyetoksylert ricinusolje, samt fremgangsmÕte til fremstilling av samme |
Country Status (14)
Country | Link |
---|---|
US (1) | US5925776A (no) |
EP (1) | EP1045825A1 (no) |
JP (1) | JP2003518140A (no) |
KR (1) | KR20010033607A (no) |
AU (1) | AU7261798A (no) |
BG (1) | BG104555A (no) |
CA (1) | CA2315853A1 (no) |
EA (1) | EA200000569A1 (no) |
HU (1) | HUP0100211A2 (no) |
IL (1) | IL136942A0 (no) |
NO (1) | NO20003206L (no) |
PL (1) | PL341757A1 (no) |
SK (1) | SK9682000A3 (no) |
WO (1) | WO1999033780A1 (no) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100330373B1 (ko) * | 1996-05-28 | 2002-11-07 | 주식회사한국신약 | 탁솔을 함유한 주사용 약제 조성물 |
KR19990075621A (ko) * | 1998-03-23 | 1999-10-15 | 임성주 | 경사 평판형 배양조 |
WO2000023070A1 (en) | 1998-10-20 | 2000-04-27 | Ben Venue Laboratories, Inc. | Process for purification of solvents useful in the preparation of pharmaceutical compositions |
US6828346B2 (en) * | 1999-10-25 | 2004-12-07 | Supergen, Inc. | Methods for administration of paclitaxel |
US6136846A (en) * | 1999-10-25 | 2000-10-24 | Supergen, Inc. | Formulation for paclitaxel |
AR027519A1 (es) * | 2000-01-20 | 2003-04-02 | Baker Norton Pharma | Purificacion de aceites de castor polioxietilados con carbon activado |
WO2002043765A2 (en) * | 2000-11-28 | 2002-06-06 | Transform Pharmaceuticals, Inc. | Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof |
WO2002058689A1 (en) | 2000-12-05 | 2002-08-01 | Childrens Hospital Los Angeles | Pharmaceutical compositions of fenretinide having increased bioavailability and methods of using the same |
CA2466851C (en) * | 2001-11-26 | 2012-09-11 | Supergen, Inc. | Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions |
WO2003045357A1 (en) * | 2001-11-27 | 2003-06-05 | Transform Pharmaceuticals, Inc. | Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof |
CZ294371B6 (cs) * | 2002-06-10 | 2004-12-15 | Pliva - Lachema, A. S. | Stabilizovaná farmaceutická kompozice na bázi polyoxyethylovaného ricinového oleje a způsob její přípravy |
US20060263327A1 (en) * | 2003-03-19 | 2006-11-23 | Gerhard Eidenhammer | Method for the production of a stable injectable formulation made of difficult to dissolve antineoplastic active substances |
US20050016926A1 (en) * | 2003-07-24 | 2005-01-27 | Dabur Research Foundation | Stabilized formulation |
US20050256097A1 (en) * | 2004-05-11 | 2005-11-17 | Kosan Biosciences, Inc. | Pharmaceutical solution formulations containing 17-AAG |
RU2008100219A (ru) * | 2005-06-21 | 2009-07-27 | Дзе Кока-Кола Компани (US) | Способ удаления примесей из эфирных масел |
CA2620585C (en) | 2005-08-31 | 2015-04-28 | Abraxis Bioscience, Llc | Compositions comprising poorly water soluble pharmaceutical agents and antimicrobial agents |
AU2007219104B2 (en) * | 2006-02-21 | 2010-07-01 | Dabur Pharma Limited | Stable pharmaceutical composition of taxanes |
EP2777691A1 (en) * | 2013-03-14 | 2014-09-17 | Pharmachemie B.V. | Taxoid - Purification of Liquid Excipients |
CN112778513A (zh) * | 2020-12-30 | 2021-05-11 | 江苏优仿医药科技有限公司 | 一种聚氧乙烯蓖麻油的精制方法及其应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4960799A (en) * | 1988-09-13 | 1990-10-02 | Ciba-Geigy Corporation | Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use |
US5015744A (en) * | 1989-11-14 | 1991-05-14 | Florida State University | Method for preparation of taxol using an oxazinone |
US5407683A (en) * | 1990-06-01 | 1995-04-18 | Research Corporation Technologies, Inc. | Pharmaceutical solutions and emulsions containing taxol |
FR2698543B1 (fr) * | 1992-12-02 | 1994-12-30 | Rhone Poulenc Rorer Sa | Nouvelles compositions à base de taxoides. |
TW406020B (en) * | 1993-09-29 | 2000-09-21 | Bristol Myers Squibb Co | Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent |
US5415869A (en) * | 1993-11-12 | 1995-05-16 | The Research Foundation Of State University Of New York | Taxol formulation |
US5462726A (en) * | 1993-12-17 | 1995-10-31 | Bristol-Myers Squibb Company | Method of inhibiting side effects of solvents containing ricinoleic acid or castor oil or derivatives thereof employing a thromboxane A2 receptor antagonist and pharmaceutical compositions containing such solvents |
US5681846A (en) * | 1995-03-17 | 1997-10-28 | Board Of Regents, The University Of Texas System | Extended stability formulations for paclitaxel |
-
1997
- 1997-12-24 US US08/998,306 patent/US5925776A/en not_active Expired - Fee Related
-
1998
- 1998-04-28 JP JP2000526467A patent/JP2003518140A/ja not_active Withdrawn
- 1998-04-28 IL IL13694298A patent/IL136942A0/xx unknown
- 1998-04-28 EP EP98919938A patent/EP1045825A1/en not_active Withdrawn
- 1998-04-28 EA EA200000569A patent/EA200000569A1/ru unknown
- 1998-04-28 CA CA002315853A patent/CA2315853A1/en not_active Abandoned
- 1998-04-28 PL PL98341757A patent/PL341757A1/xx unknown
- 1998-04-28 SK SK968-2000A patent/SK9682000A3/sk unknown
- 1998-04-28 WO PCT/US1998/008521 patent/WO1999033780A1/en not_active Application Discontinuation
- 1998-04-28 KR KR1020007007120A patent/KR20010033607A/ko not_active Application Discontinuation
- 1998-04-28 HU HU0100211A patent/HUP0100211A2/hu unknown
- 1998-04-28 AU AU72617/98A patent/AU7261798A/en not_active Abandoned
-
2000
- 2000-06-21 NO NO20003206A patent/NO20003206L/no not_active Application Discontinuation
- 2000-06-23 BG BG104555A patent/BG104555A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
HUP0100211A2 (hu) | 2001-06-28 |
KR20010033607A (ko) | 2001-04-25 |
JP2003518140A (ja) | 2003-06-03 |
EP1045825A1 (en) | 2000-10-25 |
CA2315853A1 (en) | 1999-07-08 |
WO1999033780A1 (en) | 1999-07-08 |
NO20003206D0 (no) | 2000-06-21 |
EA200000569A1 (ru) | 2001-04-23 |
IL136942A0 (en) | 2001-06-14 |
SK9682000A3 (en) | 2000-12-11 |
PL341757A1 (en) | 2001-05-07 |
AU7261798A (en) | 1999-07-19 |
BG104555A (en) | 2001-08-31 |
US5925776A (en) | 1999-07-20 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |