DE69026112D1 - Nichtoxidierend wirkende ophthalmische zusammensetzungen und verfahren zu ihrer konservierung und anwendung - Google Patents

Nichtoxidierend wirkende ophthalmische zusammensetzungen und verfahren zu ihrer konservierung und anwendung

Info

Publication number
DE69026112D1
DE69026112D1 DE69026112T DE69026112T DE69026112D1 DE 69026112 D1 DE69026112 D1 DE 69026112D1 DE 69026112 T DE69026112 T DE 69026112T DE 69026112 T DE69026112 T DE 69026112T DE 69026112 D1 DE69026112 D1 DE 69026112D1
Authority
DE
Germany
Prior art keywords
methods
compositions
preservation
oxidizing
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69026112T
Other languages
English (en)
Other versions
DE69026112T2 (de
Inventor
Anthony Dziabo
Michelle Wong
Peter Gyulai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Application granted granted Critical
Publication of DE69026112D1 publication Critical patent/DE69026112D1/de
Publication of DE69026112T2 publication Critical patent/DE69026112T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/12—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/143—Quaternary ammonium compounds
    • A61L12/145—Polymeric quaternary ammonium compounds
DE69026112T 1990-01-05 1990-12-18 Nichtoxidierend wirkende ophthalmische zusammensetzungen und verfahren zu ihrer konservierung und anwendung Expired - Fee Related DE69026112T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/461,181 US5145643A (en) 1990-01-05 1990-01-05 Nonoxidative ophthalmic compositions and methods for preserving and using same
PCT/US1990/007479 WO1991009523A1 (en) 1990-01-05 1990-12-18 Non oxidative ophthalmic compositions and methods for preserving and using same

Publications (2)

Publication Number Publication Date
DE69026112D1 true DE69026112D1 (de) 1996-04-25
DE69026112T2 DE69026112T2 (de) 1996-11-21

Family

ID=23831522

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69026112T Expired - Fee Related DE69026112T2 (de) 1990-01-05 1990-12-18 Nichtoxidierend wirkende ophthalmische zusammensetzungen und verfahren zu ihrer konservierung und anwendung

Country Status (17)

Country Link
US (1) US5145643A (de)
EP (1) EP0509017B1 (de)
JP (1) JP2877513B2 (de)
AT (1) ATE135589T1 (de)
AU (1) AU636443B2 (de)
CA (1) CA2070286C (de)
DE (1) DE69026112T2 (de)
DK (1) DK0509017T3 (de)
ES (1) ES2085467T3 (de)
GR (1) GR3020062T3 (de)
HK (1) HK1005308A1 (de)
IE (1) IE74684B1 (de)
IL (1) IL96786A (de)
NZ (1) NZ236515A (de)
PT (1) PT96430A (de)
WO (1) WO1991009523A1 (de)
ZA (1) ZA9168B (de)

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US5451398A (en) * 1990-01-05 1995-09-19 Allergan, Inc. Ophthalmic and disinfecting compositions and methods for preserving and using same
JP3058656B2 (ja) * 1990-06-18 2000-07-04 トーメー産業株式会社 コンタクトレンズ用液剤組成物及びそれを用いたコンタクトレンズの洗浄若しくは保存方法
US5356555A (en) * 1992-09-14 1994-10-18 Allergan, Inc. Non-oxidative method and composition for simultaneously cleaning and disinfecting contact lenses using a protease with a disinfectant
US5352833A (en) * 1992-10-26 1994-10-04 Isp Investments Inc. Antibacterial polymeric quaternary ammonium compounds
US5300287A (en) 1992-11-04 1994-04-05 Alcon Laboratories, Inc. Polymeric antimicrobials and their use in pharmaceutical compositions
TW243455B (de) * 1993-02-09 1995-03-21 Ciba Geigy
US5419897A (en) * 1993-04-09 1995-05-30 Buckman Laboratories International, Inc. Ionene polymers as anthelmintics in animals
IL109705A (en) * 1993-06-17 1998-07-15 Allergan Inc Enzyme compositions and methods for contact lens cleaning
US5783532A (en) * 1993-06-17 1998-07-21 Allergan Enzyme compositions and methods for contact lens cleaning
JPH0776700A (ja) * 1993-07-14 1995-03-20 Senju Pharmaceut Co Ltd コンタクトレンズ用剤の安定化方法
US5536494A (en) * 1994-10-04 1996-07-16 Alcon Laboratories, Inc. Polyethylene oxide-containing quaternary ammunium polymers and pharmaceutical compositions containing an antimicrobial amount of same
US5603929A (en) * 1994-11-16 1997-02-18 Alcon Laboratories, Inc. Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
US5858346A (en) * 1997-05-09 1999-01-12 Allergan Compositions and methods for enhancing contact lens wearability
EP1041885B1 (de) * 1997-12-23 2002-10-23 Rhodia Consumer Specialties Limited Biozide zusammemsetzungen und behandlungen
JP3605329B2 (ja) * 1999-12-03 2004-12-22 日華化学株式会社 眼科用液剤及びコンタクトレンズ用液剤
CA2395866C (en) 2000-01-25 2009-10-13 Alcon, Inc. Ophthalmic anti-allergy compositions suitable for use with contact lenses
JP3784609B2 (ja) * 2000-03-31 2006-06-14 日華化学株式会社 繊維用抗菌剤及び抗菌性繊維製品
AUPQ679100A0 (en) * 2000-04-07 2000-05-11 Novapharm Research (Australia) Pty Ltd Process and composition for cleaning medical instruments
JP3542940B2 (ja) * 2001-04-27 2004-07-14 日華化学株式会社 殺菌消毒剤、抗菌性薬剤及び抗菌性材料
US20040191332A1 (en) * 2003-03-27 2004-09-30 Allergan, Inc. Preserved ophthalmic compositions
US20090004288A1 (en) * 2007-06-29 2009-01-01 Collins Gary L Stabilized ophthalmic solutions
US20090145086A1 (en) * 2007-12-11 2009-06-11 Reynolds Ger M Method for treating ophthalmic lenses
US20090145091A1 (en) * 2007-12-11 2009-06-11 Richard Connolly Method for treating ophthalmic lenses
DE202009019116U1 (de) 2008-03-17 2016-08-01 Alcon Research, Ltd. Wässrige pharmazeutische Zusammensetzungen, die Borat-Polyol-Komplexe enthalten
TWI544927B (zh) 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
US20090239775A1 (en) * 2008-03-19 2009-09-24 Collins Gary L Ophthalmic solutions displaying improved efficacy
US8093352B2 (en) * 2008-08-05 2012-01-10 Alcon Research, Ltd. Polyalkylene oxide polyquaternary ammonium biocides
TW201023912A (en) 2008-12-05 2010-07-01 Alcon Res Ltd Pharmaceutical suspension
WO2010101989A1 (en) 2009-03-03 2010-09-10 Alcon Research, Ltd. PHARMACEUTICAL COMPOSITION FOR DELIVERY OF RECEPTOR TYROSINE KINASE INHIBITING (RTKi) COMPOUNDS TO THE EYE
TW201038295A (en) 2009-04-17 2010-11-01 Alcon Res Ltd Aqueous ophthalmic compositions containing anionic therapeutic agents
TWI489997B (zh) 2009-06-19 2015-07-01 Alcon Res Ltd 含有硼酸－多元醇錯合物之水性藥學組成物
TWI478730B (zh) 2009-12-03 2015-04-01 Alcon Res Ltd 眼科乳劑
EP2699228A2 (de) 2011-04-22 2014-02-26 Alcon Research, Ltd. Ophthalmische zusammensetzung mit einem viskositätsverstärkungssystem mit zwei unterschiedlichen viskositätsverstärkern
KR20140022901A (ko) 2011-04-22 2014-02-25 알콘 리서치, 리미티드 2종의 상이한 점도 증강제를 포함하는 점도 증강 시스템을 갖는 안과 조성물
TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物
TW201336527A (zh) 2012-02-10 2013-09-16 Alcon Res Ltd 具增強的穩定性之水性藥學組成物
US10174006B2 (en) 2013-06-06 2019-01-08 Novartis Ag Topical aqueous ophthalmic compositions containing a 1H-indole-1-carboxamide derivative and use thereof for treatment of ophthalmic disease
TW201938141A (zh) 2018-02-21 2019-10-01 瑞士商諾華公司 基於脂質的眼用乳劑
US11364253B2 (en) 2018-07-02 2022-06-21 Ayuvis Research, Inc. Immunodulating small molecules
EP3924345A1 (de) 2019-02-15 2021-12-22 Novartis AG Kristalline formen von 4-(7-hydroxy-2-isopropyl-4-oxo-4h-chinazolin-3-yl)-benzonitril und deren formulierungen
JP6994061B2 (ja) 2019-02-15 2022-01-14 ノバルティス アーゲー ４－（７－ヒドロキシ－２－イソプロピル－４－オキソ－４ｈ－キナゾリン－３－イル）－ベンゾニトリルの製剤
WO2022029656A1 (en) 2020-08-06 2022-02-10 Novartis Ag Crystalline forms of 4-(7-hydroxy-2-isopropyl-4-oxo-4h-quinazolin-3-yl)-benzonitrile and formulations thereof
WO2024062389A1 (en) 2022-09-21 2024-03-28 Bausch + Lomb Ireland Limited Crystalline polymorph forms of a trpv1 antagonist and formulations thereof

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3771989A (en) * 1971-11-26 1973-11-13 Buckman Labor Inc Method of controlling the growth of algae
US3910296A (en) * 1973-04-20 1975-10-07 Allergan Pharma Method of removing proteinaceous deposits from contact lenses
US3912451A (en) * 1973-06-04 1975-10-14 Warner Lambert Co Method for removing hydrogen peroxide from soft contact lenses
US4029817A (en) * 1973-09-24 1977-06-14 Allergan Pharmaceuticals Soft contact lens preserving solutions
US4168112A (en) * 1978-01-05 1979-09-18 Polymer Technology Corporation Contact lens with a hydrophilic, polyelectrolyte complex coating and method for forming same
JPS5513778A (en) * 1978-04-26 1980-01-30 Smith & Nephew Pharma Water soluble polymer*sterilization*and disinfectant colution
US4250269A (en) * 1979-11-26 1981-02-10 Buckman Laboratories, Inc. Water-soluble mixtures of quaternary ammonium polymers, nonionic and/or cationic vinyl-addition polymers, and nonionic and/or cationic surfactants
US4443429A (en) * 1980-11-28 1984-04-17 Bausch & Lomb Incorporated Contact lens disinfecting and preserving solution (polymeric)
US4499077A (en) * 1981-02-03 1985-02-12 Stockel Richard F Anti-microbial compositions and associated methods for preparing the same and for the disinfecting of various objects
US4482680A (en) * 1981-09-15 1984-11-13 Dynapol Quaternary ammonium group-containing polymers having antimicrobial activity
US4532128A (en) * 1981-09-15 1985-07-30 Dynapol Quaternary ammonium group-containing polymers having antimicrobial activity
US4525346A (en) * 1981-09-28 1985-06-25 Alcon Laboratories, Inc. Aqueous antimicrobial ophthalmic solutions
US4615882A (en) * 1982-09-27 1986-10-07 Stockel Richard F Disinfectant solution for contact lens
US4654208A (en) * 1983-03-01 1987-03-31 Stockel Richard F Anti-microbial compositions comprising an aqueous solution of a germicidal polymeric nitrogen compound and a potentiating oxidizing agent
GB2139260B (en) * 1983-05-04 1986-09-03 Unilever Plc Bleaching and cleaning composition
US4568517A (en) * 1983-08-25 1986-02-04 Barnes-Hind, Inc. Disinfection of contact lenses
US4836986A (en) * 1984-09-28 1989-06-06 Bausch & Lomb Incorporated Disinfecting and preserving systems and methods of use
USRE32672E (en) * 1985-09-09 1988-05-24 Allergan, Inc. Method for simultaneously cleaning and disinfecting contact lenses using a mixture of peroxide and proteolytic enzyme
US4786436A (en) * 1986-01-31 1988-11-22 Bausch & Lomb Incorporated Wetting solutions for contact lenses
JP2550036B2 (ja) * 1986-11-21 1996-10-30 株式会社メニコン コンタクトレンズ用液剤組成物
US4783488A (en) * 1987-01-31 1988-11-08 Bausch & Lomb Incorporated Contact lens wetting solution

Also Published As

Publication number Publication date
JPH05502874A (ja) 1993-05-20
CA2070286C (en) 2000-08-29
ES2085467T3 (es) 1996-06-01
ZA9168B (en) 1991-10-30
ATE135589T1 (de) 1996-04-15
IL96786A (en) 1995-01-24
WO1991009523A1 (en) 1991-07-11
AU7049791A (en) 1991-07-24
IE74684B1 (en) 1997-07-30
IL96786A0 (en) 1991-09-16
CA2070286A1 (en) 1992-04-06
US5145643A (en) 1992-09-08
NZ236515A (en) 1992-09-25
DE69026112T2 (de) 1996-11-21
EP0509017A1 (de) 1992-10-21
JP2877513B2 (ja) 1999-03-31
EP0509017A4 (en) 1993-02-24
IE910030A1 (en) 1991-07-17
HK1005308A1 (en) 1998-12-31
GR3020062T3 (en) 1996-08-31
DK0509017T3 (da) 1996-07-22
PT96430A (pt) 1991-10-31
AU636443B2 (en) 1993-04-29
EP0509017B1 (de) 1996-03-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee