NO20001510L - Spesifikke immunofilin-ligander som anti-asmatiske, anti- allergiske, anti-reumatiske, immunsuppressive, antipsoriatiske og neuroprotektive midler - Google Patents

Spesifikke immunofilin-ligander som anti-asmatiske, anti- allergiske, anti-reumatiske, immunsuppressive, antipsoriatiske og neuroprotektive midler

Info

Publication number
NO20001510L
NO20001510L NO20001510A NO20001510A NO20001510L NO 20001510 L NO20001510 L NO 20001510L NO 20001510 A NO20001510 A NO 20001510A NO 20001510 A NO20001510 A NO 20001510A NO 20001510 L NO20001510 L NO 20001510L
Authority
NO
Norway
Prior art keywords
asthmatic
rheumatic
immunosuppressive
allergic
antipsychotic
Prior art date
Application number
NO20001510A
Other languages
English (en)
Other versions
NO20001510D0 (no
Inventor
Dietmar Reichert
Bernhard Kutscher
Stefan Szelenyi
Hildegard Poppe
Gerhard Quinkert
Kay Brune
Holger Bang
Holger Deppe
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of NO20001510D0 publication Critical patent/NO20001510D0/no
Publication of NO20001510L publication Critical patent/NO20001510L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

De nye spesifikke immunofilin-ligander med den generelle Formel (I) har anti-astmatisk, anti-allergisk, anti-reumatisk, anti-betennelses-, immunsuppressiv, anti-psoriatisk og neuroprotektiv virkning og egner seg for fremstilling av legemidler.
NO20001510A 1997-09-25 2000-03-23 Spesifikke immunofilin-ligander som anti-asmatiske, anti- allergiske, anti-reumatiske, immunsuppressive, antipsoriatiske og neuroprotektive midler NO20001510L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742263A DE19742263A1 (de) 1997-09-25 1997-09-25 Neue spezifische Immunophilin-Liganden als Antiasthmatika, Antiallergika, Antirheumatika, Immunsuppressiva, Antipsoriatika, Neuroprotektiva
PCT/EP1998/005300 WO1999015501A1 (de) 1997-09-25 1998-08-20 Spezifische immunophilin-liganden als antiasthmatika, antiallergika, antirheumatika, immunsuppressiva, antipsoriatika, neuroprotektiva

Publications (2)

Publication Number Publication Date
NO20001510D0 NO20001510D0 (no) 2000-03-23
NO20001510L true NO20001510L (no) 2000-05-22

Family

ID=7843549

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20001510A NO20001510L (no) 1997-09-25 2000-03-23 Spesifikke immunofilin-ligander som anti-asmatiske, anti- allergiske, anti-reumatiske, immunsuppressive, antipsoriatiske og neuroprotektive midler

Country Status (12)

Country Link
EP (1) EP1017673A1 (no)
JP (1) JP2001517653A (no)
KR (1) KR20010040253A (no)
AU (1) AU9345098A (no)
BR (1) BR9813226A (no)
CA (1) CA2304451A1 (no)
DE (1) DE19742263A1 (no)
HU (1) HUP0004294A3 (no)
IL (1) IL133246A0 (no)
NO (1) NO20001510L (no)
WO (1) WO1999015501A1 (no)
ZA (1) ZA987819B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010052503A (ko) 1998-06-03 2001-06-25 다니엘 피. 맥컬럼 Ｎ-헤테로사이클릭 카복실산 또는 카복실산 등입체의ｎ-결합된 설폰아미드
US6300341B1 (en) 1998-09-30 2001-10-09 The Procter & Gamble Co. 2-substituted heterocyclic sulfonamides
US7253169B2 (en) 1999-11-12 2007-08-07 Gliamed, Inc. Aza compounds, pharmaceutical compositions and methods of use
US6417189B1 (en) 1999-11-12 2002-07-09 Gpi Nil Holdings, Inc. AZA compounds, pharmaceutical compositions and methods of use
WO2001046195A1 (en) 1999-12-21 2001-06-28 Gpi Nil Holdings, Inc. Hydantoin derivative compounds, pharmaceutical compositions, and methods of using same
CN101006053A (zh) 2004-06-18 2007-07-25 比奥里波克斯公司 用于治疗炎症的吲哚
DE602005011452D1 (de) * 2004-06-18 2009-01-15 Biolipox Ab Zur behandlung von entzündungen geeignete indole
US20110104186A1 (en) 2004-06-24 2011-05-05 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
CA2593155A1 (en) 2005-01-19 2006-07-27 Biolipox Ab Indoles useful in the treatment of inflammation
WO2013138600A1 (en) * 2012-03-16 2013-09-19 Rosen Eliot M Radioprotector compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192773A (en) * 1990-07-02 1993-03-09 Vertex Pharmaceuticals, Inc. Immunosuppressive compounds
MX9202466A (es) * 1991-05-24 1994-06-30 Vertex Pharma Compuestos inmunosupresores novedosos.
US5385918A (en) * 1993-02-09 1995-01-31 Miles Inc. Aminomethylene-peptides as immunosuppressants
US5614547A (en) * 1995-06-07 1997-03-25 Guilford Pharmaceuticals Inc. Small molecule inhibitors of rotamase enzyme
US5859031A (en) * 1995-06-07 1999-01-12 Gpi Nil Holdings, Inc. Small molecule inhibitors of rotamase enzyme activity
KR100266467B1 (ko) * 1995-09-27 2000-10-02 우에노 도시오 설폰아미드 유도체
DE19542189A1 (de) * 1995-11-13 1997-05-15 Hoechst Ag Cyclische N-substituierte alpha-Iminohydroxamsäuren
DE19616509A1 (de) * 1996-04-25 1998-01-15 Asta Medica Ag Neue spezifische Immunophilin-Liganden als Antiasthmatika, Immunsuppressiva

Also Published As

Publication number Publication date
BR9813226A (pt) 2000-08-29
KR20010040253A (ko) 2001-05-15
EP1017673A1 (de) 2000-07-12
DE19742263A1 (de) 1999-04-01
HUP0004294A2 (hu) 2001-05-28
NO20001510D0 (no) 2000-03-23
IL133246A0 (en) 2001-04-30
CA2304451A1 (en) 1999-04-01
ZA987819B (en) 1999-04-07
AU9345098A (en) 1999-04-12
WO1999015501A1 (de) 1999-04-01
HUP0004294A3 (en) 2001-11-28
JP2001517653A (ja) 2001-10-09

Similar Documents

Publication Publication Date Title
TR200100238T2 (tr) Yeni sübstitüe edilmiş pirazol türevleri
ATE309237T1 (de) Aromatische heterozyklische verbindungen als antientzündungwirkstoffe
AU2002239344A1 (en) Pyrazolopyridines
WO2001017973A3 (de) Neue herbizide
WO2002002565A3 (en) Glucocortiocoid-selective antiinflammatory agents
TR200200785T2 (tr) 8-Fenil-6,9-dihidro-[1,2,4] triazolo [3,4-i] purin-5-on türevleri
HK1030218A1 (en) Novel 2-(iminomethyl)amino-phenyl derivatives, preparation, application as medicines and compositions containing same.
NO20001510L (no) Spesifikke immunofilin-ligander som anti-asmatiske, anti- allergiske, anti-reumatiske, immunsuppressive, antipsoriatiske og neuroprotektive midler
TR200100426T2 (tr) Nematisit pirazoller
HUP0200580A2 (hu) Celecoxib polimorf kristályos formái, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
WO2005035537A3 (en) Substituted tricyclic heterocycles and their uses
NO20016151L (no) Fremstilling av substituerte piperidin-4-oner
MY125674A (en) Use of 1-hydroxy-2-pyridones for the treatment of seborrheic dermatitis
ES2104174T3 (es) Derivados de bencilamino, bencilamido y bencilimido ciclicos utilizados como agentes antipsicoticos.
DE69528065D1 (de) Azazyklohexapeptid-verbindungen
NO943765L (no) Aryloksybenzen-herbicidmidler
DE60003031T2 (de) Benzo[f]naphthyridinderivate, ihre herstellung und sie enthaltende pharmazeutische zusammenstzungen
ID27440A (id) Proses untuk menyiapkan penengah-penengah
DE60003807D1 (de) Enantiomere von mercaptolactonen und verfahren zu ihrer herstellung
DK1250335T3 (da) Fremgangsmåde og mellemprodukter til fremstilling af imidazopyridiner
AU2003227622A1 (en) Methylthiophene carboxanilides
WO2001091625A3 (en) Methods and compositions for the diagnosis of schizophrenia
BG105247A (en) N-substituted azabicycloheptane derivatives, production and use thereof
MY122950A (en) Photochromic oxazine compounds and methods for their manufacture
TR199801961T2 (xx) Yeni oksalidin t�revleri, bunlar�n �retimi i�in i�lemler ve bu bile�ikleri ihtiva eden farmas�tik maddeler.

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application