NO180719C - Analogifremgangsmåte for fremstilling av terapeutisk aktive A-nor-steroid-3-carboxylsyrederivater - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive A-nor-steroid-3-carboxylsyrederivater

Info

Publication number
NO180719C
NO180719C NO905608A NO905608A NO180719C NO 180719 C NO180719 C NO 180719C NO 905608 A NO905608 A NO 905608A NO 905608 A NO905608 A NO 905608A NO 180719 C NO180719 C NO 180719C
Authority
NO
Norway
Prior art keywords
steroid
carboxylic acid
acid derivatives
preparation
therapeutically active
Prior art date
Application number
NO905608A
Other languages
English (en)
Norwegian (no)
Other versions
NO905608D0 (no
NO180719B (no
NO905608L (no
Inventor
Gary Alan Flynn
Philippe Bey
Thomas Robert Blohm
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO905608D0 publication Critical patent/NO905608D0/no
Publication of NO905608L publication Critical patent/NO905608L/no
Publication of NO180719B publication Critical patent/NO180719B/no
Publication of NO180719C publication Critical patent/NO180719C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J61/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by contraction of only one ring by one or two atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO905608A 1989-12-29 1990-12-27 Analogifremgangsmåte for fremstilling av terapeutisk aktive A-nor-steroid-3-carboxylsyrederivater NO180719C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45886989A 1989-12-29 1989-12-29
US07/580,759 US5100917A (en) 1989-12-29 1990-09-11 Novel a-nor-steroid-3-carboxylic acid derivatives

Publications (4)

Publication Number Publication Date
NO905608D0 NO905608D0 (no) 1990-12-27
NO905608L NO905608L (no) 1991-07-01
NO180719B NO180719B (no) 1997-02-24
NO180719C true NO180719C (no) 1997-06-04

Family

ID=27039140

Family Applications (1)

Application Number Title Priority Date Filing Date
NO905608A NO180719C (no) 1989-12-29 1990-12-27 Analogifremgangsmåte for fremstilling av terapeutisk aktive A-nor-steroid-3-carboxylsyrederivater

Country Status (20)

Country Link
US (1) US5100917A (de)
EP (1) EP0435321B1 (de)
JP (1) JP3039996B2 (de)
KR (3) KR0178468B1 (de)
CN (4) CN1033809C (de)
AT (1) ATE126232T1 (de)
AU (1) AU634326B2 (de)
CA (1) CA2033392C (de)
DE (1) DE69021530T2 (de)
DK (1) DK0435321T3 (de)
ES (1) ES2078291T3 (de)
FI (1) FI94418C (de)
GR (1) GR3017559T3 (de)
HU (1) HU210340B (de)
IE (1) IE67511B1 (de)
IL (1) IL96790A (de)
MX (1) MX9203338A (de)
NO (1) NO180719C (de)
NZ (1) NZ236589A (de)
PT (1) PT96394B (de)

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US5543406A (en) * 1991-12-20 1996-08-06 Glaxo Wellcome, Inc. Inhibitors of 5-α-testosterone reductase
SK140494A3 (en) * 1992-05-21 1995-07-11 Endorecherche Inc Inhibitors of testosterone 5-alpha-reductase activity
US5302589A (en) * 1992-08-07 1994-04-12 Glaxo, Inc. Heterocyclic inhibitors of 5-α-testosterone reductase
US5561124A (en) * 1992-11-18 1996-10-01 Webb; Robert L. 17-α-acyl steroids which inhibit 5-α-reductase
GB9224148D0 (en) * 1992-11-18 1993-01-06 Smithkline Beecham Corp Compounds
TW369521B (en) * 1993-09-17 1999-09-11 Smithkline Beecham Corp Androstenone derivative
US5541322A (en) * 1994-10-14 1996-07-30 Glaxo Wellcome Inc. Synthesis of 6-azaandrostenones
US5543417A (en) * 1994-10-21 1996-08-06 Merck & Co., Inc. Combination method of treating acne using 4-AZA-5α-cholestan-ones and 4-AZA-5α-androstan-ones as selective 5α-reductase inhibitors with anti-bacterial, keratolytic, or anti-inflammatory agents
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US8119109B2 (en) * 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US9668972B2 (en) * 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US7820145B2 (en) * 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
AU2003279493B2 (en) 2002-10-25 2009-08-20 Foamix Pharmaceuticals Ltd. Cosmetic and pharmaceutical foam
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
FR2857968B1 (fr) * 2003-07-25 2006-02-03 Inovat Sarl Nouveaux derives steroides et leurs utilisations therapeuthique
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
MX2007014101A (es) * 2005-05-09 2009-02-13 Foamix Ltd Vehiculo espumable y composiciones farmaceuticas del mismo.
US20080152596A1 (en) * 2005-07-19 2008-06-26 Foamix Ltd. Polypropylene glycol foamable vehicle and pharmaceutical compositions thereof
US20080206155A1 (en) * 2006-11-14 2008-08-28 Foamix Ltd. Stable non-alcoholic foamable pharmaceutical emulsion compositions with an unctuous emollient and their uses
US20080260655A1 (en) * 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
US8518376B2 (en) 2007-12-07 2013-08-27 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009090495A2 (en) 2007-12-07 2009-07-23 Foamix Ltd. Oil and liquid silicone foamable carriers and formulations
EP2242476A2 (de) * 2008-01-14 2010-10-27 Foamix Ltd. Aufschäumbare pharmazeutische poloxamer-zusammensetzungen mit wirkstoffen und/oder therapeutischen zellen und verwendungen
WO2010125470A2 (en) 2009-04-28 2010-11-04 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
MX359879B (es) 2009-10-02 2018-10-12 Foamix Pharmaceuticals Ltd Composiciones tópicas de tetraciclina.
JP5527236B2 (ja) * 2011-01-31 2014-06-18 信越化学工業株式会社 ポジ型化学増幅レジスト材料、パターン形成方法及び酸分解性ケトエステル化合物
CA2978573A1 (en) 2016-09-08 2018-03-08 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne

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US3600425A (en) * 1963-09-13 1971-08-17 Squibb & Sons Inc Synthesis of steroids
US3484476A (en) * 1963-09-13 1969-12-16 Squibb & Sons Inc A-nor steroids
US3336338A (en) * 1963-09-13 1967-08-15 Squibb & Sons Inc A-nor-cholestatriene-21-oic acid 21->24 lactones
US3424751A (en) * 1965-10-20 1969-01-28 Du Pont Selected 2-formyl-and 2alpha-(cyanoamidino)-a-nor-5alpha-androstane derivatives
US3492359A (en) * 1966-01-14 1970-01-27 Squibb & Sons Inc 11,12-oxo and/or oxy substituted a-norpregnenes
US4910226A (en) * 1987-04-29 1990-03-20 Smithkline Beckman Corporation Steroid 5-alpha-reductase inhibitors

Also Published As

Publication number Publication date
CN1127256A (zh) 1996-07-24
NO905608D0 (no) 1990-12-27
JPH04134094A (ja) 1992-05-07
CN1052866A (zh) 1991-07-10
AU634326B2 (en) 1993-02-18
NZ236589A (en) 1993-02-25
EP0435321B1 (de) 1995-08-09
AU6844790A (en) 1991-07-04
DE69021530T2 (de) 1996-02-01
US5100917A (en) 1992-03-31
FI906438L (fi) 1991-06-30
CA2033392A1 (en) 1991-06-30
ATE126232T1 (de) 1995-08-15
FI906438A0 (fi) 1990-12-28
KR0178468B1 (ko) 1999-04-01
HU210340B (en) 1995-03-28
FI94418B (fi) 1995-05-31
NO180719B (no) 1997-02-24
FI94418C (fi) 1995-09-11
KR0178471B1 (ko) 1999-04-01
NO905608L (no) 1991-07-01
KR910011887A (ko) 1991-08-07
IL96790A (en) 1995-03-15
CN1127258A (zh) 1996-07-24
ES2078291T3 (es) 1995-12-16
DE69021530D1 (de) 1995-09-14
MX9203338A (es) 1992-09-01
CN1033809C (zh) 1997-01-15
CA2033392C (en) 2002-08-27
IE904720A1 (en) 1991-07-17
HU908495D0 (en) 1991-07-29
IL96790A0 (en) 1991-09-16
DK0435321T3 (da) 1995-09-18
KR0178470B1 (ko) 1999-04-01
IE67511B1 (en) 1996-04-03
HUT56379A (en) 1991-08-28
CN1127257A (zh) 1996-07-24
CN1036200C (zh) 1997-10-22
PT96394A (pt) 1991-10-15
GR3017559T3 (en) 1995-12-31
EP0435321A3 (en) 1992-04-29
PT96394B (pt) 1998-10-30
EP0435321A2 (de) 1991-07-03
JP3039996B2 (ja) 2000-05-08

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