NO180485C - NMDA-antagonister - Google Patents

NMDA-antagonister

Info

Publication number
NO180485C
NO180485C NO933042A NO933042A NO180485C NO 180485 C NO180485 C NO 180485C NO 933042 A NO933042 A NO 933042A NO 933042 A NO933042 A NO 933042A NO 180485 C NO180485 C NO 180485C
Authority
NO
Norway
Prior art keywords
nmda antagonists
nmda
antagonists
sulfanimide
directed
Prior art date
Application number
NO933042A
Other languages
English (en)
Other versions
NO933042D0 (no
NO180485B (no
NO933042L (no
Inventor
Boyd Lynn Harrison
Bruce Michael Baron
David M Stemerick
Ian Alexander Mcdonald
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO933042D0 publication Critical patent/NO933042D0/no
Publication of NO933042L publication Critical patent/NO933042L/no
Publication of NO180485B publication Critical patent/NO180485B/no
Publication of NO180485C publication Critical patent/NO180485C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO933042A 1991-02-27 1993-08-26 NMDA-antagonister NO180485C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66178091A 1991-02-27 1991-02-27
US70000491A 1991-05-14 1991-05-14
PCT/US1992/001093 WO1992015565A1 (en) 1991-02-27 1992-02-11 Nmda antagonists

Publications (4)

Publication Number Publication Date
NO933042D0 NO933042D0 (no) 1993-08-26
NO933042L NO933042L (no) 1993-08-26
NO180485B NO180485B (no) 1997-01-20
NO180485C true NO180485C (no) 1997-04-30

Family

ID=27098383

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933042A NO180485C (no) 1991-02-27 1993-08-26 NMDA-antagonister

Country Status (14)

Country Link
EP (1) EP0573562B1 (no)
JP (1) JP3465794B2 (no)
KR (1) KR100224045B1 (no)
AT (1) ATE137225T1 (no)
AU (1) AU660969B2 (no)
CA (1) CA2104297C (no)
DE (1) DE69210229T2 (no)
DK (1) DK0573562T3 (no)
ES (1) ES2089511T3 (no)
FI (1) FI103202B (no)
GR (1) GR3019772T3 (no)
HU (1) HU217425B (no)
NO (1) NO180485C (no)
WO (1) WO1992015565A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5318985A (en) * 1991-12-20 1994-06-07 Merrell Dow Pharmaceuticals Inc. Potentiation of NMDA antagonists
ATE404201T1 (de) * 1992-06-22 2008-08-15 Univ California Glycinrezeptorantagonisten und ihre verwendung
US5475007A (en) * 1993-05-28 1995-12-12 The Regents Of The University Of California 1,2,3,4-tetrahydroquinoline-2,3,4-trione-3 or 4-oximes and the use thereof
DE69416324T2 (de) * 1993-11-29 1999-06-10 Merrell Pharmaceuticals Inc., Cincinnati, Ohio Heterocyclische benzolsulfonyliminderivate als inhibitoren der il-1 wirkung
ES2131297T3 (es) * 1993-11-29 1999-07-16 Merrell Pharma Inc Nuevos derivados de bencenosulfonilamina como inhibidores de la accion il-1.
CA2788656A1 (en) 2010-02-16 2011-08-25 Pfizer Inc. (r)-4-((4-((4-(tetrahydrofuran-3-yloxy)benzo[d]isoxazol-3-yloxy)methyl)piperidin-1-yl)methyl)tetrahydro-2h-pyran-4-ol, a partial agonist of 5-ht4 receptors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8719102D0 (en) * 1987-08-12 1987-09-16 Merck Sharp & Dohme Therapeutic agents
IL93610A0 (en) * 1989-03-08 1990-12-23 Merck Sharp & Dohme Tetrahydroquinoline derivatives,their preparation and pharmaceutical compositions containing them
ZA903588B (en) * 1989-05-16 1991-02-27 Merrell Dow Pharma Excitatory amino acid antagonists

Also Published As

Publication number Publication date
WO1992015565A1 (en) 1992-09-17
AU660969B2 (en) 1995-07-13
DE69210229D1 (de) 1996-05-30
JP3465794B2 (ja) 2003-11-10
DE69210229T2 (de) 1996-11-14
ATE137225T1 (de) 1996-05-15
HU9302433D0 (en) 1993-11-29
NO933042D0 (no) 1993-08-26
CA2104297A1 (en) 1992-08-28
FI103202B1 (fi) 1999-05-14
HUT67301A (en) 1995-03-28
GR3019772T3 (en) 1996-07-31
DK0573562T3 (da) 1996-05-13
NO180485B (no) 1997-01-20
FI933762A (fi) 1993-08-26
AU1532092A (en) 1992-10-06
EP0573562A1 (en) 1993-12-15
FI933762A0 (fi) 1993-08-26
JPH06505746A (ja) 1994-06-30
HU217425B (hu) 2000-01-28
KR100224045B1 (ko) 1999-10-15
EP0573562B1 (en) 1996-04-24
FI103202B (fi) 1999-05-14
ES2089511T3 (es) 1996-10-01
CA2104297C (en) 2003-05-27
KR930703257A (ko) 1993-11-29
NO933042L (no) 1993-08-26

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees