DK0573562T3 - Dihydroquinolin NMDA-antagonister - Google Patents
Dihydroquinolin NMDA-antagonisterInfo
- Publication number
- DK0573562T3 DK0573562T3 DK92907466.4T DK92907466T DK0573562T3 DK 0573562 T3 DK0573562 T3 DK 0573562T3 DK 92907466 T DK92907466 T DK 92907466T DK 0573562 T3 DK0573562 T3 DK 0573562T3
- Authority
- DK
- Denmark
- Prior art keywords
- dihydroquinoline
- nmda antagonists
- nmda
- antagonists
- sulfanimide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66178091A | 1991-02-27 | 1991-02-27 | |
US70000491A | 1991-05-14 | 1991-05-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0573562T3 true DK0573562T3 (da) | 1996-05-13 |
Family
ID=27098383
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK92907466.4T DK0573562T3 (da) | 1991-02-27 | 1992-02-11 | Dihydroquinolin NMDA-antagonister |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0573562B1 (no) |
JP (1) | JP3465794B2 (no) |
KR (1) | KR100224045B1 (no) |
AT (1) | ATE137225T1 (no) |
AU (1) | AU660969B2 (no) |
CA (1) | CA2104297C (no) |
DE (1) | DE69210229T2 (no) |
DK (1) | DK0573562T3 (no) |
ES (1) | ES2089511T3 (no) |
FI (1) | FI103202B1 (no) |
GR (1) | GR3019772T3 (no) |
HU (1) | HU217425B (no) |
NO (1) | NO180485C (no) |
WO (1) | WO1992015565A1 (no) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5318985A (en) * | 1991-12-20 | 1994-06-07 | Merrell Dow Pharmaceuticals Inc. | Potentiation of NMDA antagonists |
PT647137E (pt) * | 1992-06-22 | 2008-11-24 | Univ California | Antagonistas dos receptores da glicina e a sua utilização |
US5475007A (en) * | 1993-05-28 | 1995-12-12 | The Regents Of The University Of California | 1,2,3,4-tetrahydroquinoline-2,3,4-trione-3 or 4-oximes and the use thereof |
AU683114B2 (en) * | 1993-11-29 | 1997-10-30 | Merrell Pharmaceuticals Inc. | Novel benzenesulfonylimine derivatives as inhibitors of IL-1 action |
WO1995014670A1 (en) * | 1993-11-29 | 1995-06-01 | Merrell Pharmaceuticals Inc. | Heterocyclic benzenesulfonylimine derivatives as inhibitors of il-1 action |
AU2011216950A1 (en) | 2010-02-16 | 2012-08-23 | Pfizer Inc. | (R)-4-((4-((4-(tetrahydrofuran-3-yloxy) benzo[d]isoxazol-3-yloxy)methyl)piperidin-1-yl)methyl)tetrahydro-2H-pyran-4-ol, a partial agonist of 5-HT4 receptors |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8719102D0 (en) * | 1987-08-12 | 1987-09-16 | Merck Sharp & Dohme | Therapeutic agents |
DE69029668T2 (de) * | 1989-03-08 | 1997-08-07 | Merck Sharp & Dohme | Tetrahydroquinolin-Derivate, verwendbar bei neurodegenerativen Krankheiten |
NZ233641A (en) * | 1989-05-16 | 1992-07-28 | Merrell Dow Pharma | Quinoline and thienopyridine derivatives and excitatory amino acid antagonistic pharmaceutical compositions |
-
1992
- 1992-02-11 HU HU9302433A patent/HU217425B/hu not_active IP Right Cessation
- 1992-02-11 WO PCT/US1992/001093 patent/WO1992015565A1/en active IP Right Grant
- 1992-02-11 DE DE69210229T patent/DE69210229T2/de not_active Expired - Lifetime
- 1992-02-11 JP JP50728592A patent/JP3465794B2/ja not_active Expired - Lifetime
- 1992-02-11 CA CA002104297A patent/CA2104297C/en not_active Expired - Lifetime
- 1992-02-11 ES ES92907466T patent/ES2089511T3/es not_active Expired - Lifetime
- 1992-02-11 AU AU15320/92A patent/AU660969B2/en not_active Ceased
- 1992-02-11 DK DK92907466.4T patent/DK0573562T3/da active
- 1992-02-11 EP EP92907466A patent/EP0573562B1/en not_active Expired - Lifetime
- 1992-02-11 KR KR1019930702559A patent/KR100224045B1/ko not_active IP Right Cessation
- 1992-02-11 AT AT92907466T patent/ATE137225T1/de not_active IP Right Cessation
-
1993
- 1993-08-26 NO NO933042A patent/NO180485C/no not_active IP Right Cessation
- 1993-08-26 FI FI933762A patent/FI103202B1/fi active
-
1996
- 1996-04-25 GR GR960401099T patent/GR3019772T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
FI933762A0 (fi) | 1993-08-26 |
ES2089511T3 (es) | 1996-10-01 |
JP3465794B2 (ja) | 2003-11-10 |
KR100224045B1 (ko) | 1999-10-15 |
FI103202B (fi) | 1999-05-14 |
WO1992015565A1 (en) | 1992-09-17 |
HUT67301A (en) | 1995-03-28 |
ATE137225T1 (de) | 1996-05-15 |
GR3019772T3 (en) | 1996-07-31 |
DE69210229T2 (de) | 1996-11-14 |
CA2104297A1 (en) | 1992-08-28 |
DE69210229D1 (de) | 1996-05-30 |
KR930703257A (ko) | 1993-11-29 |
EP0573562B1 (en) | 1996-04-24 |
FI933762A (fi) | 1993-08-26 |
AU1532092A (en) | 1992-10-06 |
JPH06505746A (ja) | 1994-06-30 |
NO180485B (no) | 1997-01-20 |
NO933042L (no) | 1993-08-26 |
FI103202B1 (fi) | 1999-05-14 |
HU217425B (hu) | 2000-01-28 |
CA2104297C (en) | 2003-05-27 |
NO180485C (no) | 1997-04-30 |
EP0573562A1 (en) | 1993-12-15 |
HU9302433D0 (en) | 1993-11-29 |
AU660969B2 (en) | 1995-07-13 |
NO933042D0 (no) | 1993-08-26 |
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