NO180198C - Peptidsyntese-fremgangsmåte og fast bærer for anvendelse i fremgangsmåten - Google Patents

Peptidsyntese-fremgangsmåte og fast bærer for anvendelse i fremgangsmåten

Info

Publication number
NO180198C
NO180198C NO910812A NO910812A NO180198C NO 180198 C NO180198 C NO 180198C NO 910812 A NO910812 A NO 910812A NO 910812 A NO910812 A NO 910812A NO 180198 C NO180198 C NO 180198C
Authority
NO
Norway
Prior art keywords
solid support
peptide synthesis
synthesis method
peptide
solid
Prior art date
Application number
NO910812A
Other languages
English (en)
Norwegian (no)
Other versions
NO180198B (no
NO910812D0 (no
NO910812L (no
Inventor
Rolf H Berg
Kristoffer Almdal
Walther Batsberg Pedersen
Arne Holm
James P Tam
Robert Bruce Merrifield
Original Assignee
Risoe Forskningscenter
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Risoe Forskningscenter filed Critical Risoe Forskningscenter
Publication of NO910812D0 publication Critical patent/NO910812D0/no
Publication of NO910812L publication Critical patent/NO910812L/no
Publication of NO180198B publication Critical patent/NO180198B/no
Publication of NO180198C publication Critical patent/NO180198C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Peptides Or Proteins (AREA)
NO910812A 1988-09-01 1991-02-28 Peptidsyntese-fremgangsmåte og fast bærer for anvendelse i fremgangsmåten NO180198C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23952588A 1988-09-01 1988-09-01
PCT/DK1989/000201 WO1990002749A1 (fr) 1988-09-01 1989-08-31 Procede de synthese de peptides et support solide de realisation dudit procede

Publications (4)

Publication Number Publication Date
NO910812D0 NO910812D0 (no) 1991-02-28
NO910812L NO910812L (no) 1991-04-26
NO180198B NO180198B (no) 1996-11-25
NO180198C true NO180198C (no) 1997-03-05

Family

ID=22902538

Family Applications (1)

Application Number Title Priority Date Filing Date
NO910812A NO180198C (no) 1988-09-01 1991-02-28 Peptidsyntese-fremgangsmåte og fast bærer for anvendelse i fremgangsmåten

Country Status (8)

Country Link
EP (1) EP0433345B1 (fr)
JP (1) JP2807522B2 (fr)
AU (1) AU4225889A (fr)
CA (1) CA1339987C (fr)
DE (1) DE68914843T2 (fr)
FI (1) FI102833B1 (fr)
NO (1) NO180198C (fr)
WO (1) WO1990002749A1 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK55990D0 (da) * 1990-03-02 1990-03-02 Risoe Forskningscenter Faste baerematerialer til anvendelse i biosystemer
DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
US5719262A (en) * 1993-11-22 1998-02-17 Buchardt, Deceased; Ole Peptide nucleic acids having amino acid side chains
US5766855A (en) * 1991-05-24 1998-06-16 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity and sequence specificity
US6451968B1 (en) 1991-05-24 2002-09-17 Isis Pharmaceuticals, Inc. Peptide nucleic acids
US6441130B1 (en) 1991-05-24 2002-08-27 Isis Pharmaceuticals, Inc. Linked peptide nucleic acids
US5714331A (en) * 1991-05-24 1998-02-03 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
US6713602B1 (en) 1991-05-24 2004-03-30 Ole Buchardt Synthetic procedures for peptide nucleic acids
US7223833B1 (en) 1991-05-24 2007-05-29 Isis Pharmaceuticals, Inc. Peptide nucleic acid conjugates
US6414112B1 (en) 1991-05-24 2002-07-02 Ole Buchardt Peptide nucleic acids having 2,6-diaminopurine nucleobases
DK72493D0 (da) * 1993-06-18 1993-06-18 Risoe Forskningscenter Solid supports for use in peptide synthesis and assays
US6710164B1 (en) 1993-11-22 2004-03-23 Peter E. Nielsen Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
US6133444A (en) * 1993-12-22 2000-10-17 Perseptive Biosystems, Inc. Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions
US5629152A (en) * 1994-08-01 1997-05-13 Isis Pharmaceuticals, Inc. Trisubstituted β-lactams and oligo β-lactamamides
DE69632324T2 (de) * 1995-06-07 2005-06-16 PerSeptive Biosystems, Inc., Framingham Pna-dna-chimäre und pna-synthone zu deren herstellung
GB9727126D0 (en) * 1997-12-22 1998-02-25 Zeneca Ltd Process
US20040076623A1 (en) * 2000-07-14 2004-04-22 Ede Nicholas Jon Activated modular grafted polymeric surfaces
AUPR224600A0 (en) 2000-12-21 2001-01-25 Polymerat Pty Ltd Novel polymers
AU2002367825A1 (en) * 2001-07-30 2003-10-13 Sts Biopolymers, Inc. Graft polymer matrices
US7169916B2 (en) 2002-04-01 2007-01-30 Isis Pharmaceuticals, Inc. Chloral-free DCA in oligonucleotide synthesis
ES2373714T3 (es) 2002-05-10 2012-02-08 Bio-Layer Pty Limited Generación de diversidad de recubrimientos de superficie.
EP1692139B1 (fr) 2003-11-13 2013-02-13 Isis Pharmaceuticals, Inc. Derives de 5, 6-dihydroxy-isoindole en tant que lieurs pour la synthese d'oligomeres en phase solide
AU2004296412B2 (en) 2003-12-12 2011-03-10 Anteo Technologies Pty Ltd A method for designing surfaces
EP1773866B1 (fr) 2004-07-02 2013-06-19 Bio-Layer Pty Limited Usage de complexes métalliques
US8636978B2 (en) 2008-06-23 2014-01-28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cyclized NGR peptide compounds, compositions, and methods of their use
EP2885312A4 (fr) 2012-08-15 2016-01-20 Isis Pharmaceuticals Inc Procédé de préparation de composés oligomères utilisant des protocoles de coiffage modifiés
US20190275072A1 (en) 2016-05-24 2019-09-12 Sarepta Therapeutics, Inc. Pharmaceutical compositions comprising eteplirsen
US11472824B2 (en) 2016-05-24 2022-10-18 Sarepta Therapeutics, Inc. Processes for preparing phosphorodiamidate morpholino oligomers
KR102506298B1 (ko) 2016-05-24 2023-03-06 사렙타 쎄러퓨틱스 인코퍼레이티드 올리고머의 제조 방법
MA45362A (fr) 2016-05-24 2019-04-10 Sarepta Therapeutics Inc Procédés de préparation d'oligomères morpholino de phosphorodiamidate
MX2018014123A (es) 2016-05-24 2019-04-29 Sarepta Therapeutics Inc Procesos para preparar oligomeros de morfolino fosforodiamidato.
SG11201809499UA (en) 2016-05-24 2018-12-28 Sarepta Therapeutics Inc Processes for preparing phosphorodiamidate morpholino oligomers
JP7022079B2 (ja) 2016-06-30 2022-02-17 サレプタ セラピューティクス， インコーポレイテッド ホスホロジアミダートモルホリノオリゴマーを調製するためのプロセス
WO2021025899A1 (fr) 2019-08-02 2021-02-11 Sarepta Therapeutics, Inc. Compositions pharmaceutiques à base d'oligomères morpholino phosphorodiamidate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1593880A1 (de) * 1967-06-16 1970-10-29 Farbwerk Hoechst Ag Vorm Meist Verfahren zur Herstellung von Peptiden
AU426743B2 (en) * 1967-09-21 1972-07-21 MONASH UNIVERSITY, and ICI AUSTRALIA LIMITED Processes forthe production of peptides and proteins
FR2078974A5 (fr) * 1970-02-25 1971-11-05 Hoffmann La Roche

Also Published As

Publication number Publication date
DE68914843T2 (de) 1994-11-10
FI102833B (fi) 1999-02-26
AU4225889A (en) 1990-04-02
EP0433345A1 (fr) 1991-06-26
NO180198B (no) 1996-11-25
JP2807522B2 (ja) 1998-10-08
JPH04501709A (ja) 1992-03-26
DE68914843D1 (de) 1994-05-26
NO910812D0 (no) 1991-02-28
WO1990002749A1 (fr) 1990-03-22
FI102833B1 (fi) 1999-02-26
CA1339987C (fr) 1998-08-04
FI911029A0 (fi) 1991-02-28
NO910812L (no) 1991-04-26
EP0433345B1 (fr) 1994-04-20

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN FEBRUARY 2002