NO179695C - Anvendelse av æomega-[4-(2-pyrimidinyl)-1-piperazinylÅalkylå-1H-azol-derivater for fremstilling av medisinske produkter beregnet til behandling av forstyrrelser i kognitive funksjoner - Google Patents
Anvendelse av æomega-[4-(2-pyrimidinyl)-1-piperazinylÅalkylå-1H-azol-derivater for fremstilling av medisinske produkter beregnet til behandling av forstyrrelser i kognitive funksjonerInfo
- Publication number
- NO179695C NO179695C NO920342A NO920342A NO179695C NO 179695 C NO179695 C NO 179695C NO 920342 A NO920342 A NO 920342A NO 920342 A NO920342 A NO 920342A NO 179695 C NO179695 C NO 179695C
- Authority
- NO
- Norway
- Prior art keywords
- radical
- disorders
- treatment
- aryl
- cognitive functions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9100861A FR2671972B1 (fr) | 1991-01-25 | 1991-01-25 | Utilisation de derives 1-h-azole-(omega-(4-(2-pyrimidinyl)-1-piperazinyl)-alkyl) pour la preparation de medicaments destines au traitement des troubles des fonctions cognitives. |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO920342D0 NO920342D0 (no) | 1992-01-24 |
| NO920342L NO920342L (no) | 1992-07-27 |
| NO179695B NO179695B (no) | 1996-08-26 |
| NO179695C true NO179695C (no) | 1996-12-04 |
Family
ID=9409058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO920342A NO179695C (no) | 1991-01-25 | 1992-01-24 | Anvendelse av æomega-[4-(2-pyrimidinyl)-1-piperazinylÅalkylå-1H-azol-derivater for fremstilling av medisinske produkter beregnet til behandling av forstyrrelser i kognitive funksjoner |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5182281A (de) |
| EP (1) | EP0497658B1 (de) |
| JP (1) | JPH07121865B2 (de) |
| KR (1) | KR970001655B1 (de) |
| AT (1) | ATE126227T1 (de) |
| AU (1) | AU646137B2 (de) |
| CA (1) | CA2059984A1 (de) |
| DE (1) | DE69203874T2 (de) |
| DK (1) | DK0497658T3 (de) |
| ES (1) | ES2125207B1 (de) |
| FR (1) | FR2671972B1 (de) |
| GR (1) | GR3017648T3 (de) |
| HU (1) | HU214319B (de) |
| NO (1) | NO179695C (de) |
| RU (1) | RU2078568C1 (de) |
| ZA (1) | ZA92504B (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5681956A (en) * | 1990-12-28 | 1997-10-28 | Neurogen Corporation | 4-aryl substituted piperazinylmethyl phenylimidazole derivatives; a new class of dopamine receptor subtype specific ligands |
| US5646281A (en) * | 1990-12-28 | 1997-07-08 | Neurogen Corporation | Certain 4-piperidino- and piperazinomethyl-2-phenyl imidazole derivatives; dopamine receptor subtype specific ligands |
| FR2701260B1 (fr) * | 1993-02-05 | 1995-05-05 | Esteve Labor Dr | Dérivés de 2-[4-(4-azolylbutyl)-1-pipérazinyl]-5-hydroxypyrimidine, leur préparation et leur application en tant que médicaments. |
| FR2705098B1 (fr) * | 1993-05-10 | 1995-08-04 | Esteve Labor Dr | Procédé de préparation de 2-{4-[4-(chloro-1-pyrazolyl)butyl]1-pipérazinyl}pyrimidine (Lesopitron) . |
| GB9408084D0 (en) * | 1994-04-23 | 1994-06-15 | Boots Co Plc | Medical treatment |
| FR2723091B1 (fr) * | 1994-07-29 | 1996-11-08 | Esteve Labor Dr | Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles |
| US6355659B1 (en) | 1994-07-29 | 2002-03-12 | Laboratorios Del Dr. Esteve, S.A. | 4-(4-Chlorophenyl)-1236-tetrahydro-1(1H-124-triazol-1-yl)butty)pyrideine and salts thereof; pharmaceutical compositions and method of treating psychoses utilizing same |
| ES2117934B1 (es) * | 1994-07-29 | 1999-04-01 | Esteve Labor Dr | Tetrahidropiridinas (0 4-hidroxipiperidinas) alquilazoles. |
| ES2099031B1 (es) * | 1995-05-31 | 1997-12-01 | Esteve Labor Dr | Nuevos polimorfos de diclorhidrato de lesopitron y sus formas hidratadas, procedimientos de preparacion y composiciones que los contienen. |
| US6166205A (en) * | 1998-09-02 | 2000-12-26 | Neurogen Corporation | 2-Aryl-4-(1-[4-heteroaryl]piperazin-1-yl)methylimidazoles: dopamine . D.sub4 receptor subtype ligands |
| US9161783B2 (en) | 2004-10-20 | 2015-10-20 | Vertiflex, Inc. | Interspinous spacer |
| US8123807B2 (en) | 2004-10-20 | 2012-02-28 | Vertiflex, Inc. | Systems and methods for posterior dynamic stabilization of the spine |
| US8273108B2 (en) | 2004-10-20 | 2012-09-25 | Vertiflex, Inc. | Interspinous spacer |
| US8945183B2 (en) * | 2004-10-20 | 2015-02-03 | Vertiflex, Inc. | Interspinous process spacer instrument system with deployment indicator |
| US8167944B2 (en) | 2004-10-20 | 2012-05-01 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for posterior dynamic stabilization of the spine |
| US9023084B2 (en) * | 2004-10-20 | 2015-05-05 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for stabilizing the motion or adjusting the position of the spine |
| US8277488B2 (en) * | 2004-10-20 | 2012-10-02 | Vertiflex, Inc. | Interspinous spacer |
| US8128662B2 (en) | 2004-10-20 | 2012-03-06 | Vertiflex, Inc. | Minimally invasive tooling for delivery of interspinous spacer |
| US7763074B2 (en) | 2004-10-20 | 2010-07-27 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for posterior dynamic stabilization of the spine |
| US8123782B2 (en) * | 2004-10-20 | 2012-02-28 | Vertiflex, Inc. | Interspinous spacer |
| US8409282B2 (en) | 2004-10-20 | 2013-04-02 | Vertiflex, Inc. | Systems and methods for posterior dynamic stabilization of the spine |
| US8012207B2 (en) * | 2004-10-20 | 2011-09-06 | Vertiflex, Inc. | Systems and methods for posterior dynamic stabilization of the spine |
| US9119680B2 (en) | 2004-10-20 | 2015-09-01 | Vertiflex, Inc. | Interspinous spacer |
| US8613747B2 (en) * | 2004-10-20 | 2013-12-24 | Vertiflex, Inc. | Spacer insertion instrument |
| US8152837B2 (en) | 2004-10-20 | 2012-04-10 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for posterior dynamic stabilization of the spine |
| US8317864B2 (en) | 2004-10-20 | 2012-11-27 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for posterior dynamic stabilization of the spine |
| US8425559B2 (en) | 2004-10-20 | 2013-04-23 | Vertiflex, Inc. | Systems and methods for posterior dynamic stabilization of the spine |
| WO2009086010A2 (en) | 2004-12-06 | 2009-07-09 | Vertiflex, Inc. | Spacer insertion instrument |
| US8845726B2 (en) | 2006-10-18 | 2014-09-30 | Vertiflex, Inc. | Dilator |
| WO2008130564A1 (en) | 2007-04-16 | 2008-10-30 | Vertiflex Inc. | Interspinous spacer |
| AU2009206098B2 (en) * | 2008-01-15 | 2014-10-30 | Vertiflex, Inc. | Interspinous spacer |
| WO2011084477A2 (en) | 2009-12-15 | 2011-07-14 | Vertifex, Inc. | Spinal spacer for cervical and other vertebra, and associated systems and methods |
| US9675303B2 (en) | 2013-03-15 | 2017-06-13 | Vertiflex, Inc. | Visualization systems, instruments and methods of using the same in spinal decompression procedures |
| US10524772B2 (en) | 2014-05-07 | 2020-01-07 | Vertiflex, Inc. | Spinal nerve decompression systems, dilation systems, and methods of using the same |
| US12102542B2 (en) | 2022-02-15 | 2024-10-01 | Boston Scientific Neuromodulation Corporation | Interspinous spacer and methods and systems utilizing the interspinous spacer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2642759B1 (fr) * | 1989-02-09 | 1991-05-17 | Laboratorios Esteve Sa | Derives de pyrimidyl-piperazinyl-alkyl azoles avec activite anxiolytique et/ou tranquillisante |
| FR2654621B1 (fr) * | 1989-11-22 | 1994-09-23 | Esteve Labor Dr | Inhibition du syndrome d'abstinence. |
-
1991
- 1991-01-25 FR FR9100861A patent/FR2671972B1/fr not_active Expired - Lifetime
-
1992
- 1992-01-17 ES ES9200092A patent/ES2125207B1/es not_active Expired - Fee Related
- 1992-01-22 DK DK92400163.9T patent/DK0497658T3/da active
- 1992-01-22 DE DE69203874T patent/DE69203874T2/de not_active Expired - Fee Related
- 1992-01-22 AT AT92400163T patent/ATE126227T1/de not_active IP Right Cessation
- 1992-01-22 EP EP92400163A patent/EP0497658B1/de not_active Expired - Lifetime
- 1992-01-23 AU AU10445/92A patent/AU646137B2/en not_active Ceased
- 1992-01-24 NO NO920342A patent/NO179695C/no not_active IP Right Cessation
- 1992-01-24 JP JP4011131A patent/JPH07121865B2/ja not_active Expired - Lifetime
- 1992-01-24 CA CA002059984A patent/CA2059984A1/fr not_active Abandoned
- 1992-01-24 HU HU9200232A patent/HU214319B/hu not_active IP Right Cessation
- 1992-01-24 ZA ZA92504A patent/ZA92504B/xx unknown
- 1992-01-24 KR KR1019920001052A patent/KR970001655B1/ko not_active IP Right Cessation
- 1992-01-24 RU SU925010696A patent/RU2078568C1/ru active
- 1992-01-24 US US07/824,995 patent/US5182281A/en not_active Expired - Fee Related
-
1995
- 1995-10-04 GR GR950402761T patent/GR3017648T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO920342D0 (no) | 1992-01-24 |
| NO920342L (no) | 1992-07-27 |
| CA2059984A1 (fr) | 1992-07-26 |
| ATE126227T1 (de) | 1995-08-15 |
| DE69203874T2 (de) | 1995-12-07 |
| US5182281A (en) | 1993-01-26 |
| RU2078568C1 (ru) | 1997-05-10 |
| KR970001655B1 (ko) | 1997-02-13 |
| JPH04312529A (ja) | 1992-11-04 |
| AU1044592A (en) | 1992-07-30 |
| KR920014472A (ko) | 1992-08-25 |
| ZA92504B (en) | 1992-10-28 |
| EP0497658B1 (de) | 1995-08-09 |
| GR3017648T3 (en) | 1996-01-31 |
| EP0497658A1 (de) | 1992-08-05 |
| ES2125207B1 (es) | 1999-01-01 |
| DE69203874D1 (de) | 1995-09-14 |
| DK0497658T3 (da) | 1995-10-02 |
| HU214319B (hu) | 1998-03-02 |
| HU9200232D0 (en) | 1992-04-28 |
| NO179695B (no) | 1996-08-26 |
| AU646137B2 (en) | 1994-02-10 |
| FR2671972A1 (fr) | 1992-07-31 |
| HUT60433A (en) | 1992-09-28 |
| FR2671972B1 (fr) | 1995-03-03 |
| JPH07121865B2 (ja) | 1995-12-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN JULY 2002 |