DE69001526D1 - Verwendung von trifluormethylphenyltetrahydropyridinen zur herstellung von arzneimitteln zur bekaempfung intestinaler motilitaetsstoerungen. - Google Patents

Verwendung von trifluormethylphenyltetrahydropyridinen zur herstellung von arzneimitteln zur bekaempfung intestinaler motilitaetsstoerungen.

Info

Publication number
DE69001526D1
DE69001526D1 DE9090402257T DE69001526T DE69001526D1 DE 69001526 D1 DE69001526 D1 DE 69001526D1 DE 9090402257 T DE9090402257 T DE 9090402257T DE 69001526 T DE69001526 T DE 69001526T DE 69001526 D1 DE69001526 D1 DE 69001526D1
Authority
DE
Germany
Prior art keywords
group
trifluormethylphenyltetrahydropyridines
kills
production
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE9090402257T
Other languages
English (en)
Other versions
DE69001526T2 (de
Inventor
Alberto Bianchetti
Tiziano Croci
Luciano Manara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Elf Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elf Sanofi SA filed Critical Elf Sanofi SA
Publication of DE69001526D1 publication Critical patent/DE69001526D1/de
Application granted granted Critical
Publication of DE69001526T2 publication Critical patent/DE69001526T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE90402257T 1989-08-07 1990-08-07 Verwendung von Trifluormethylphenyltetrahydropyridinen zur Herstellung von Arzneimitteln zur Bekämpfung intestinaler Motilitätsstörungen. Expired - Fee Related DE69001526T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8910617A FR2650505B1 (fr) 1989-08-07 1989-08-07 Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale

Publications (2)

Publication Number Publication Date
DE69001526D1 true DE69001526D1 (de) 1993-06-09
DE69001526T2 DE69001526T2 (de) 1993-10-28

Family

ID=9384538

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90402257T Expired - Fee Related DE69001526T2 (de) 1989-08-07 1990-08-07 Verwendung von Trifluormethylphenyltetrahydropyridinen zur Herstellung von Arzneimitteln zur Bekämpfung intestinaler Motilitätsstörungen.

Country Status (6)

Country Link
US (1) US5109005A (de)
EP (1) EP0412901B1 (de)
JP (1) JP2952425B2 (de)
AT (1) ATE88892T1 (de)
DE (1) DE69001526T2 (de)
FR (1) FR2650505B1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618822A (en) * 1990-05-23 1997-04-08 Sanofi N-substituted trifluoromethylphenyltetrahydropyridines, process for the preparation thereof, intermediates in said process and pharmaceutical compositions containing them
FR2662442A1 (fr) * 1990-05-23 1991-11-29 Midy Spa Trifluoromethylphenyltetrahydropyridines n-substituees procede pour leur preparation, intermediaires du procede et compositions pharmaceutiques les contenant.
FR2672213B1 (fr) * 1991-02-05 1995-03-10 Sanofi Sa Utilisation de derives 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridiniques comme capteurs de radicaux libres.
FR2690158B1 (fr) * 1992-04-17 1994-07-22 Sanofi Elf Nouveau derive arylpiperidinique, procede pour sa preparation et compositions pharmaceutiques le contenant.
FR2702656B1 (fr) * 1993-03-18 1995-06-16 Sanofi Elf Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments cardioprotecteurs.
FR2736053B1 (fr) * 1995-06-28 1997-09-19 Sanofi Sa Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines
FR2757160B1 (fr) * 1996-12-13 1999-03-12 Sanofi Sa 1-phenylalkyl-1,2,3,6-tetrahydropyridines
FR2757161B1 (fr) * 1996-12-13 1999-03-12 Sanofi Sa Diphenylalkyl-tetrahydropyridines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR86403E (fr) * 1959-05-01 1966-02-04 May & Baker Ltd Nouveaux dérivés de la phényl-4 pipéridine et leur préparation
US4691019A (en) * 1981-03-11 1987-09-01 Sanofi Anorectic agent; 4-(3-trifluoromethylphenyl)-1-(2-cyanoethyl)-1,2,3,6-tetrahydropyridine
FR2501682A1 (fr) * 1981-03-11 1982-09-17 Sanofi Sa Trifluoromethylphenylpyridines a activite anorexigene, un procede de preparation et compositions pharmaceutiques en contenant
FR2531707A1 (fr) * 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques

Also Published As

Publication number Publication date
JPH0377824A (ja) 1991-04-03
EP0412901A3 (en) 1991-05-08
EP0412901B1 (de) 1993-05-05
FR2650505A1 (fr) 1991-02-08
FR2650505B1 (fr) 1994-06-03
US5109005A (en) 1992-04-28
ATE88892T1 (de) 1993-05-15
EP0412901A2 (de) 1991-02-13
JP2952425B2 (ja) 1999-09-27
DE69001526T2 (de) 1993-10-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-SYNTHELABO, PARIS, FR

8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-AVENTIS, PARIS, FR

8339 Ceased/non-payment of the annual fee