NO179249C - Analogifremgangsmåte for fremstilling av terapeutisk aktive 4,6- disubstituerte 2,3-dikarboksylsyreindolderivater - Google Patents
Analogifremgangsmåte for fremstilling av terapeutisk aktive 4,6- disubstituerte 2,3-dikarboksylsyreindolderivaterInfo
- Publication number
- NO179249C NO179249C NO930035A NO930035A NO179249C NO 179249 C NO179249 C NO 179249C NO 930035 A NO930035 A NO 930035A NO 930035 A NO930035 A NO 930035A NO 179249 C NO179249 C NO 179249C
- Authority
- NO
- Norway
- Prior art keywords
- disubstituted
- preparation
- dicarboxylic acid
- indole derivatives
- therapeutically active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55605790A | 1990-07-16 | 1990-07-16 | |
PCT/US1991/004253 WO1992001670A1 (en) | 1990-07-16 | 1991-06-17 | Excitatory amino acid antagonists |
Publications (4)
Publication Number | Publication Date |
---|---|
NO930035D0 NO930035D0 (no) | 1993-01-07 |
NO930035L NO930035L (no) | 1993-01-07 |
NO179249B NO179249B (no) | 1996-05-28 |
NO179249C true NO179249C (no) | 1996-09-04 |
Family
ID=24219725
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO930035A NO179249C (no) | 1990-07-16 | 1993-01-07 | Analogifremgangsmåte for fremstilling av terapeutisk aktive 4,6- disubstituerte 2,3-dikarboksylsyreindolderivater |
Country Status (15)
Country | Link |
---|---|
US (1) | US5106847A (es) |
EP (1) | EP0539503B1 (es) |
JP (1) | JP3058688B2 (es) |
KR (1) | KR0178469B1 (es) |
AT (1) | ATE136295T1 (es) |
AU (1) | AU646686B2 (es) |
CA (1) | CA2087091C (es) |
DE (1) | DE69118539T2 (es) |
DK (1) | DK0539503T3 (es) |
ES (1) | ES2088011T3 (es) |
FI (1) | FI98455C (es) |
GR (1) | GR3019689T3 (es) |
HU (1) | HU216787B (es) |
NO (1) | NO179249C (es) |
WO (1) | WO1992001670A1 (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5189054A (en) * | 1990-11-02 | 1993-02-23 | Merrell Dow Pharmaceuticals Inc. | 3-amidoindolyl derivatives and pharmaceutical compositions thereof |
US5318985A (en) * | 1991-12-20 | 1994-06-07 | Merrell Dow Pharmaceuticals Inc. | Potentiation of NMDA antagonists |
GB9208492D0 (en) * | 1992-04-16 | 1992-06-03 | Glaxo Spa | Heterocyclic compounds |
USRE39300E1 (en) | 1993-01-28 | 2006-09-19 | Virginia Commonwealth University Medical College Of Virginia | Inhibiting the development of tolerance to and/or dependence on an addictive substance |
US5321012A (en) * | 1993-01-28 | 1994-06-14 | Virginia Commonwealth University Medical College | Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance |
US5519048A (en) * | 1993-05-27 | 1996-05-21 | Merrell Pharmaceuticals Inc. | 3-(indol-3-yl)-propenoic acid derivatives and pharmaceutical compositions thereof |
TW280819B (es) * | 1993-11-17 | 1996-07-11 | Sumitomo Pharma | |
US5696148A (en) * | 1994-03-14 | 1997-12-09 | Novo Nordisk A/S | Indole compounds and their use in treating diseases of the central nervous system |
US5783575A (en) * | 1994-03-14 | 1998-07-21 | Novo Nordisk A/S | Antagonists, their preparation and use |
US5563157B1 (en) * | 1994-10-31 | 1999-02-02 | Hoecst Marion Roussel Inc | Heterocycle substituted propenoic acid derivatives and pharmaceutical compositions thereof |
GB9502695D0 (en) * | 1995-02-11 | 1995-03-29 | Glaxo Spa | Pharmaceutical composition |
JPH11509847A (ja) * | 1995-07-31 | 1999-08-31 | ノボ ノルディスク アクティーゼルスカブ | ヘテロ環式化合物、それらの調製及び使用 |
EP0929521B1 (en) * | 1996-09-30 | 2005-11-09 | Aventis Pharmaceuticals Inc. | Nmda (n-methyl-d-aspartate) antagonists |
DE69826881T2 (de) * | 1997-03-14 | 2005-12-01 | Smithkline Beecham Corp. | Neue indolcarboxamide, pharmazeutische zusammensetzungen und methoden zur hemmung von calpain |
US5922752A (en) * | 1997-06-11 | 1999-07-13 | Hoechst Marion Roussell, Inc. | NMDA (n-methyl-d-aspartate) antagonists |
AU2002250256B2 (en) * | 2001-03-08 | 2008-04-03 | Emory University | pH-dependent NMDA receptor antagonists |
US20030162825A1 (en) * | 2001-11-09 | 2003-08-28 | Sepracor Inc. | D-amino acid oxidase inhibitors for learning and memory |
US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
MX2009014216A (es) * | 2007-06-29 | 2010-07-05 | Univ Emory | Antagonistas del receptor nmda para neuroproteccion. |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4960786A (en) * | 1989-04-24 | 1990-10-02 | Merrell Dow Pharmaceuticals Inc. | Excitatory amino acid antagonists |
JPH0347123A (ja) * | 1989-05-05 | 1991-02-28 | G D Searle & Co | インドール―2―カルボキシレート化合物類を含有するcns疾患治療用組成物 |
CA2091257A1 (en) * | 1990-09-10 | 1992-03-11 | Fu-Chih Huang | Substituted bicyclic aryl compounds exhibiting selective leukotriene b4 antagonists activity |
WO1993005020A1 (en) * | 1991-09-06 | 1993-03-18 | Merck & Co., Inc. | Indoles as inhibitors of hiv reverse transcriptase |
-
1991
- 1991-06-17 KR KR1019930700112A patent/KR0178469B1/ko not_active IP Right Cessation
- 1991-06-17 AT AT91913891T patent/ATE136295T1/de not_active IP Right Cessation
- 1991-06-17 AU AU82908/91A patent/AU646686B2/en not_active Ceased
- 1991-06-17 DK DK91913891.7T patent/DK0539503T3/da active
- 1991-06-17 WO PCT/US1991/004253 patent/WO1992001670A1/en active IP Right Grant
- 1991-06-17 JP JP3512894A patent/JP3058688B2/ja not_active Expired - Fee Related
- 1991-06-17 CA CA002087091A patent/CA2087091C/en not_active Expired - Fee Related
- 1991-06-17 DE DE69118539T patent/DE69118539T2/de not_active Expired - Fee Related
- 1991-06-17 HU HU9300100A patent/HU216787B/hu not_active IP Right Cessation
- 1991-06-17 EP EP91913891A patent/EP0539503B1/en not_active Expired - Lifetime
- 1991-06-17 ES ES91913891T patent/ES2088011T3/es not_active Expired - Lifetime
- 1991-08-01 US US07/742,146 patent/US5106847A/en not_active Expired - Fee Related
-
1993
- 1993-01-07 NO NO930035A patent/NO179249C/no unknown
- 1993-01-14 FI FI930150A patent/FI98455C/fi active
-
1996
- 1996-04-19 GR GR960401068T patent/GR3019689T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NO930035D0 (no) | 1993-01-07 |
CA2087091C (en) | 2001-09-11 |
ATE136295T1 (de) | 1996-04-15 |
DK0539503T3 (da) | 1996-05-13 |
AU646686B2 (en) | 1994-03-03 |
FI930150A0 (fi) | 1993-01-14 |
JPH05508857A (ja) | 1993-12-09 |
ES2088011T3 (es) | 1996-08-01 |
US5106847A (en) | 1992-04-21 |
FI98455B (fi) | 1997-03-14 |
FI98455C (fi) | 1997-06-25 |
EP0539503A4 (es) | 1994-03-23 |
DE69118539T2 (de) | 1996-09-19 |
KR0178469B1 (ko) | 1999-03-20 |
HUT67237A (en) | 1995-03-28 |
JP3058688B2 (ja) | 2000-07-04 |
FI930150A (fi) | 1993-01-14 |
EP0539503A1 (en) | 1993-05-05 |
HU9300100D0 (en) | 1993-04-28 |
AU8290891A (en) | 1992-02-18 |
NO179249B (no) | 1996-05-28 |
GR3019689T3 (en) | 1996-07-31 |
DE69118539D1 (de) | 1996-05-09 |
EP0539503B1 (en) | 1996-04-03 |
NO930035L (no) | 1993-01-07 |
CA2087091A1 (en) | 1992-01-17 |
WO1992001670A1 (en) | 1992-02-06 |
HU216787B (hu) | 1999-08-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO179249C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive 4,6- disubstituerte 2,3-dikarboksylsyreindolderivater | |
AU625998B2 (en) | Excitatory amino acid antagonists | |
NO180084C (no) | Analogifremgangsmåte ved fremstilling av terapeutisk aktive 1,4-dihydropyridinderivater | |
NO178857C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive 3-indolylthioacetatderivater | |
NO175976C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive 4-(1,6-dihydro-6-okso-pyridazinyl-3-oksy)-3-kromanolderivater | |
NO901391L (no) | Fremgangsmaate for fremstilling av et 1,8-naftyridin-derivat. | |
FI900145A (fi) | Menetelmä farmaseuttisesti käyttökelpoisten 1,1-diokso-kefem-4-karbotiolihappojohdannaisten valmistamiseksi | |
FI906084A (fi) | Menetelmä uusien terapeuttisesti käyttökelpoisten 5-(2-metyyli-4,4,4-trifluoributyylikarbamoyyli)indolijohdannaisten valmistamiseksi | |
FI103202B1 (fi) | Menetelmä terapeuttisesti käyttökelpoisten 4-sulfonamido-1,4-dihydrokinoliiinijohdannaisten valmistamiseksi | |
NO880922D0 (no) | Fremgangsmaate for fremstilling av farmakologisk aktive benzodioksolderivater. | |
FI93216C (fi) | Analogiamenetelmä terapeuttisesti käyttökelpoisten 1,3-dioksaanialkeenihappojohdannaisten valmistamiseksi | |
FI910448A0 (fi) | Menetelmä terapeuttisesti käyttökelpoisten 1,2,3,3a,8,8a-heksahydro-1,3a,8-trimetyylipyrrolo/2,3b/indolijohdannaisten valmistamiseksi | |
NO158254C (no) | Analogifremgangsmaate for fremstilling av bicyklo(3,2,1)oktan-karboksylsyrederivater. | |
NO178375C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive NMDA-antagonister | |
NO174393C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive 6-metyl-19-nor-pregna-4,6-diener som er 17 eventuelt 21-alkylert | |
NO884442L (no) | Fremgangsmaate for fremstilling av 3,3-disubstituerte indoliner. | |
NO910564D0 (no) | Fremgangsmaate for fremstilling av azaspiro(4,5)decan-7,9-dionderivater. | |
FI970396A0 (fi) | Menetelmä terapeuttisesti aktiivisten iminosubstituoitujen syklopent(b)indolijohdannaisten valmistamiseksi | |
NO883526D0 (no) | Framgangsmaate for framstilling av 1,5-benzotiazepinderivater. | |
NO913388L (no) | Framgangsmaate for framstilling av 1,5-benzotiazepinderivater. | |
NO883525D0 (no) | Framgangsmaate for framstilling av 1,5-benzotiazepinderivater. | |
NO913422L (no) | Framgangsmaate for framstilling av 1,5-benzotiazepinderivater. | |
HU913421D0 (en) | Process for the production of pirimidino(1,6:1,2)pirido(3,4-b)indole derivatives |