NO174463C - Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrrolidinderivater - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrrolidinderivater

Info

Publication number
NO174463C
NO174463C NO892021A NO892021A NO174463C NO 174463 C NO174463 C NO 174463C NO 892021 A NO892021 A NO 892021A NO 892021 A NO892021 A NO 892021A NO 174463 C NO174463 C NO 174463C
Authority
NO
Norway
Prior art keywords
preparation
therapeutically active
pyrrolidine derivatives
analogous process
active pyrrolidine
Prior art date
Application number
NO892021A
Other languages
English (en)
Norwegian (no)
Other versions
NO174463B (no
NO892021D0 (no
NO892021L (no
Inventor
Angelo Carenzi
Dario Chiarino
Davide Della Bella
Gian Carlo Grancini
Carlo Veneziani
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT20648/88A external-priority patent/IT1217657B/it
Priority claimed from IT8919480A external-priority patent/IT1230754B/it
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of NO892021D0 publication Critical patent/NO892021D0/no
Publication of NO892021L publication Critical patent/NO892021L/no
Publication of NO174463B publication Critical patent/NO174463B/no
Publication of NO174463C publication Critical patent/NO174463C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • C07D211/76Oxygen atoms attached in position 2 or 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
NO892021A 1988-05-20 1989-05-19 Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrrolidinderivater NO174463C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20648/88A IT1217657B (it) 1988-05-20 1988-05-20 Composti con attivita' analgesica centrale
IT8919480A IT1230754B (it) 1989-02-17 1989-02-17 Camposti con attivita' analgesica centrale.

Publications (4)

Publication Number Publication Date
NO892021D0 NO892021D0 (no) 1989-05-19
NO892021L NO892021L (no) 1989-11-21
NO174463B NO174463B (no) 1994-01-31
NO174463C true NO174463C (no) 1994-05-11

Family

ID=26327181

Family Applications (1)

Application Number Title Priority Date Filing Date
NO892021A NO174463C (no) 1988-05-20 1989-05-19 Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrrolidinderivater

Country Status (15)

Country Link
US (1) US4960788A (sv)
EP (1) EP0342613B1 (sv)
JP (1) JP2802437B2 (sv)
AU (1) AU624382B2 (sv)
CA (1) CA1336333C (sv)
DE (1) DE68903425T2 (sv)
DK (1) DK172008B1 (sv)
ES (1) ES2043943T3 (sv)
FI (1) FI90662C (sv)
GR (1) GR3006803T3 (sv)
HU (1) HU208420B (sv)
IE (1) IE61631B1 (sv)
IL (1) IL90324A0 (sv)
NO (1) NO174463C (sv)
SU (1) SU1727531A3 (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2653123B1 (fr) * 1989-10-17 1992-01-17 Roussel Uclaf Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
IT1239950B (it) * 1990-03-28 1993-11-27 Zambon Spa Processo per la preparazione di composti con attivita' analgesica centrale
IL100360A (en) * 1990-12-17 1998-08-16 Merrell Dow Pharma HISTORY OF PYROLIDINONE USED AS SUBSTANCE (S) -Vinyl and Alanyl GABA
US5208345A (en) * 1990-12-17 1993-05-04 Merrell Dow Pharmaceuticals Inc. Process for the production of (S)-vinyl and allenyl gaba
WO2004069793A2 (en) 2003-01-28 2004-08-19 Bristol-Myers Squibb Company Novel 2-substituted cyclic amines as calcium sensing receptor modulators
US7205322B2 (en) 2003-02-12 2007-04-17 Bristol-Myers Squibb Company Thiazolidine compounds as calcium sensing receptor modulators
US7265145B2 (en) 2003-05-28 2007-09-04 Bristol-Myers Squibb Company Substituted piperidines and pyrrolidines as calcium sensing receptor modulators and method
AU2006322297A1 (en) * 2005-12-07 2007-06-14 Ucb Pharma, S.A. 3-carboxy- 2-oxo-1 -pyrrolidine derivatives and their uses
CN115475162B (zh) * 2022-10-18 2023-06-02 浙江震元制药有限公司 4-异丁基-2-吡咯烷酮在制备镇痛药物中的应用、一种镇痛药物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2496163A (en) * 1948-03-30 1950-01-31 Du Pont Synthesis of a 2-substituted-5-oxopyrrolidine
BE790747A (fr) * 1971-10-30 1973-02-15 Whitefin Holding Sa Stereo-isomeres du 1-(1'-(0-chloro-benzyl)-pyrrol-2'-yl) -2-dibutyl sec.-amino-ethanol et procede pour leur preparation
IE45511B1 (en) * 1976-09-01 1982-09-08 Ciba Geigy Ag New derivatives of perhydro-aza-heterocycles and processesfor the production thereof
US4525476A (en) * 1983-05-26 1985-06-25 Warner-Lambert Company N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids and derivatives as cognition activators
FR2549053B1 (fr) * 1983-07-12 1985-12-27 Sanofi Sa Nouveaux derives de la pyrrolidine actifs sur le systeme nerveux central, leur procede de preparation, les medicaments en contenant
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
DE3420193A1 (de) * 1984-05-30 1985-12-05 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte pyrrolidinone, verfahren zu ihrer herstellung und arzneimittel

Also Published As

Publication number Publication date
NO174463B (no) 1994-01-31
SU1727531A3 (ru) 1992-04-15
DE68903425D1 (de) 1992-12-17
JPH0217176A (ja) 1990-01-22
IE61631B1 (en) 1994-11-16
CA1336333C (en) 1995-07-18
IL90324A0 (en) 1989-12-15
NO892021D0 (no) 1989-05-19
IE891578L (en) 1989-11-20
AU624382B2 (en) 1992-06-11
EP0342613B1 (en) 1992-11-11
EP0342613A1 (en) 1989-11-23
JP2802437B2 (ja) 1998-09-24
DK244389D0 (da) 1989-05-19
FI892420A0 (sv) 1989-05-19
FI90662B (sv) 1993-11-30
US4960788A (en) 1990-10-02
ES2043943T3 (es) 1994-01-01
NO892021L (no) 1989-11-21
FI892420A (sv) 1989-11-21
AU3499389A (en) 1989-11-23
DK244389A (da) 1989-12-20
GR3006803T3 (sv) 1993-06-30
HU208420B (en) 1993-10-28
FI90662C (sv) 1994-03-10
DK172008B1 (da) 1997-09-15
DE68903425T2 (de) 1993-03-25
HUT50765A (en) 1990-03-28

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