NO174463C - Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrrolidinderivater - Google Patents
Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrrolidinderivaterInfo
- Publication number
- NO174463C NO174463C NO892021A NO892021A NO174463C NO 174463 C NO174463 C NO 174463C NO 892021 A NO892021 A NO 892021A NO 892021 A NO892021 A NO 892021A NO 174463 C NO174463 C NO 174463C
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- therapeutically active
- pyrrolidine derivatives
- analogous process
- active pyrrolidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT20648/88A IT1217657B (it) | 1988-05-20 | 1988-05-20 | Composti con attivita' analgesica centrale |
| IT8919480A IT1230754B (it) | 1989-02-17 | 1989-02-17 | Camposti con attivita' analgesica centrale. |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO892021D0 NO892021D0 (no) | 1989-05-19 |
| NO892021L NO892021L (no) | 1989-11-21 |
| NO174463B NO174463B (no) | 1994-01-31 |
| NO174463C true NO174463C (no) | 1994-05-11 |
Family
ID=26327181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO892021A NO174463C (no) | 1988-05-20 | 1989-05-19 | Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrrolidinderivater |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4960788A (sv) |
| EP (1) | EP0342613B1 (sv) |
| JP (1) | JP2802437B2 (sv) |
| AU (1) | AU624382B2 (sv) |
| CA (1) | CA1336333C (sv) |
| DE (1) | DE68903425T2 (sv) |
| DK (1) | DK172008B1 (sv) |
| ES (1) | ES2043943T3 (sv) |
| FI (1) | FI90662C (sv) |
| GR (1) | GR3006803T3 (sv) |
| HU (1) | HU208420B (sv) |
| IE (1) | IE61631B1 (sv) |
| IL (1) | IL90324A0 (sv) |
| NO (1) | NO174463C (sv) |
| SU (1) | SU1727531A3 (sv) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2653123B1 (fr) * | 1989-10-17 | 1992-01-17 | Roussel Uclaf | Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
| IT1239950B (it) * | 1990-03-28 | 1993-11-27 | Zambon Spa | Processo per la preparazione di composti con attivita' analgesica centrale |
| IL100360A (en) * | 1990-12-17 | 1998-08-16 | Merrell Dow Pharma | HISTORY OF PYROLIDINONE USED AS SUBSTANCE (S) -Vinyl and Alanyl GABA |
| US5208345A (en) * | 1990-12-17 | 1993-05-04 | Merrell Dow Pharmaceuticals Inc. | Process for the production of (S)-vinyl and allenyl gaba |
| WO2004069793A2 (en) | 2003-01-28 | 2004-08-19 | Bristol-Myers Squibb Company | Novel 2-substituted cyclic amines as calcium sensing receptor modulators |
| US7205322B2 (en) | 2003-02-12 | 2007-04-17 | Bristol-Myers Squibb Company | Thiazolidine compounds as calcium sensing receptor modulators |
| US7265145B2 (en) | 2003-05-28 | 2007-09-04 | Bristol-Myers Squibb Company | Substituted piperidines and pyrrolidines as calcium sensing receptor modulators and method |
| EP1993998B1 (en) * | 2005-12-07 | 2013-08-21 | UCB Pharma, S.A. | 3-carboxy- 2-oxo-1 -pyrrolidine derivatives and their uses |
| CN115475162B (zh) * | 2022-10-18 | 2023-06-02 | 浙江震元制药有限公司 | 4-异丁基-2-吡咯烷酮在制备镇痛药物中的应用、一种镇痛药物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2496163A (en) * | 1948-03-30 | 1950-01-31 | Du Pont | Synthesis of a 2-substituted-5-oxopyrrolidine |
| BE790747A (fr) * | 1971-10-30 | 1973-02-15 | Whitefin Holding Sa | Stereo-isomeres du 1-(1'-(0-chloro-benzyl)-pyrrol-2'-yl) -2-dibutyl sec.-amino-ethanol et procede pour leur preparation |
| IE45511B1 (en) * | 1976-09-01 | 1982-09-08 | Ciba Geigy Ag | New derivatives of perhydro-aza-heterocycles and processesfor the production thereof |
| US4525476A (en) * | 1983-05-26 | 1985-06-25 | Warner-Lambert Company | N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids and derivatives as cognition activators |
| FR2549053B1 (fr) * | 1983-07-12 | 1985-12-27 | Sanofi Sa | Nouveaux derives de la pyrrolidine actifs sur le systeme nerveux central, leur procede de preparation, les medicaments en contenant |
| DE3336024A1 (de) * | 1983-10-04 | 1985-04-18 | Boehringer Ingelheim KG, 6507 Ingelheim | 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel |
| DE3420193A1 (de) * | 1984-05-30 | 1985-12-05 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue substituierte pyrrolidinone, verfahren zu ihrer herstellung und arzneimittel |
-
1989
- 1989-05-16 IE IE157889A patent/IE61631B1/en unknown
- 1989-05-16 ES ES89108788T patent/ES2043943T3/es not_active Expired - Lifetime
- 1989-05-16 CA CA000599865A patent/CA1336333C/en not_active Expired - Fee Related
- 1989-05-16 DE DE8989108788T patent/DE68903425T2/de not_active Expired - Fee Related
- 1989-05-16 EP EP89108788A patent/EP0342613B1/en not_active Expired - Lifetime
- 1989-05-17 IL IL90324A patent/IL90324A0/xx not_active IP Right Cessation
- 1989-05-19 AU AU34993/89A patent/AU624382B2/en not_active Ceased
- 1989-05-19 US US07/354,361 patent/US4960788A/en not_active Expired - Lifetime
- 1989-05-19 FI FI892420A patent/FI90662C/sv not_active IP Right Cessation
- 1989-05-19 SU SU894614156A patent/SU1727531A3/ru active
- 1989-05-19 HU HU892506A patent/HU208420B/hu not_active IP Right Cessation
- 1989-05-19 NO NO892021A patent/NO174463C/no unknown
- 1989-05-19 DK DK244389A patent/DK172008B1/da not_active IP Right Cessation
- 1989-05-19 JP JP1127714A patent/JP2802437B2/ja not_active Expired - Lifetime
-
1993
- 1993-01-14 GR GR930400058T patent/GR3006803T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3006803T3 (sv) | 1993-06-30 |
| DK244389A (da) | 1989-12-20 |
| IE891578L (en) | 1989-11-20 |
| HU208420B (en) | 1993-10-28 |
| DK244389D0 (da) | 1989-05-19 |
| DE68903425T2 (de) | 1993-03-25 |
| FI90662B (sv) | 1993-11-30 |
| DE68903425D1 (de) | 1992-12-17 |
| AU3499389A (en) | 1989-11-23 |
| NO174463B (no) | 1994-01-31 |
| CA1336333C (en) | 1995-07-18 |
| JPH0217176A (ja) | 1990-01-22 |
| JP2802437B2 (ja) | 1998-09-24 |
| FI892420A (sv) | 1989-11-21 |
| AU624382B2 (en) | 1992-06-11 |
| ES2043943T3 (es) | 1994-01-01 |
| US4960788A (en) | 1990-10-02 |
| IL90324A0 (en) | 1989-12-15 |
| EP0342613B1 (en) | 1992-11-11 |
| EP0342613A1 (en) | 1989-11-23 |
| SU1727531A3 (ru) | 1992-04-15 |
| HUT50765A (en) | 1990-03-28 |
| NO892021L (no) | 1989-11-21 |
| FI892420A0 (sv) | 1989-05-19 |
| NO892021D0 (no) | 1989-05-19 |
| IE61631B1 (en) | 1994-11-16 |
| DK172008B1 (da) | 1997-09-15 |
| FI90662C (sv) | 1994-03-10 |
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