NO173604C - Analogifremgangsmaate til fremstilling av bis-dioksopiperazinderivater - Google Patents

Analogifremgangsmaate til fremstilling av bis-dioksopiperazinderivater

Info

Publication number
NO173604C
NO173604C NO874197A NO874197A NO173604C NO 173604 C NO173604 C NO 173604C NO 874197 A NO874197 A NO 874197A NO 874197 A NO874197 A NO 874197A NO 173604 C NO173604 C NO 173604C
Authority
NO
Norway
Prior art keywords
bis
preparation
analogous procedure
dioxopiperazine derivatives
dioxopiperazine
Prior art date
Application number
NO874197A
Other languages
English (en)
Norwegian (no)
Other versions
NO874197L (no
NO874197D0 (no
NO173604B (no
Inventor
Takase Muneaki
Cai Jun-Chao
Original Assignee
Zenyaku Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zenyaku Kogyo Kk filed Critical Zenyaku Kogyo Kk
Publication of NO874197D0 publication Critical patent/NO874197D0/no
Publication of NO874197L publication Critical patent/NO874197L/no
Publication of NO173604B publication Critical patent/NO173604B/no
Publication of NO173604C publication Critical patent/NO173604C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO874197A 1986-02-07 1987-10-07 Analogifremgangsmaate til fremstilling av bis-dioksopiperazinderivater NO173604C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2519186 1986-02-07
PCT/JP1987/000074 WO1987004707A1 (en) 1986-02-07 1987-02-05 Bis-dioxopiperazine derivatives
CA000536472A CA1305484C (en) 1986-02-07 1987-05-06 Bis-dioxopiperazine derivatives and process for preparation thereof

Publications (4)

Publication Number Publication Date
NO874197D0 NO874197D0 (no) 1987-10-07
NO874197L NO874197L (no) 1987-12-07
NO173604B NO173604B (no) 1993-09-27
NO173604C true NO173604C (no) 1994-01-05

Family

ID=25671332

Family Applications (1)

Application Number Title Priority Date Filing Date
NO874197A NO173604C (no) 1986-02-07 1987-10-07 Analogifremgangsmaate til fremstilling av bis-dioksopiperazinderivater

Country Status (8)

Country Link
US (1) US4868303A (da)
EP (1) EP0256137B1 (da)
JP (1) JPH0674251B2 (da)
CA (1) CA1305484C (da)
DE (1) DE3783176T2 (da)
DK (1) DK156831C (da)
NO (1) NO173604C (da)
WO (1) WO1987004707A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3050598B2 (ja) * 1990-07-04 2000-06-12 全薬工業株式会社 水溶性ビスージオキソピペラジン誘導体
WO1993008288A1 (en) * 1991-10-23 1993-04-29 Cancer Research Campaign Technology Limited Bacterial nitroreductase for the reduction of cb 1954 and analogues thereof to a cytotoxic form
WO2014107622A1 (en) 2013-01-07 2014-07-10 University Of Southern California Deoxyuridine triphosphatase inhibitors
JP6513095B2 (ja) * 2014-01-03 2019-05-15 ユニバーシティ オブ サザン カリフォルニア ヘテロ原子含有デオキシウリジントリホスファターゼ阻害剤
US10577321B2 (en) 2015-07-08 2020-03-03 University Of Southern California Deoxyuridine triphosphatase inhibitors
US10544105B2 (en) 2015-07-08 2020-01-28 Cv6 Therapeutics (Ni) Limited Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage
EP3319939A1 (en) 2015-07-08 2018-05-16 CV6 Therapeutics (NI) Limited Hydantoin containing deoxyuridine triphosphatase inhibitors
WO2017006271A1 (en) 2015-07-08 2017-01-12 University Of Southern California Deoxyuridine triphosphatase inhibitors containing amino sulfonyl linkage
US11168059B2 (en) 2016-11-23 2021-11-09 Cv6 Therapeutics (Ni) Limited Amino sulfonyl compounds
US11174271B2 (en) 2016-11-23 2021-11-16 Cv6 Therapeutics (Ni) Limited 6-membered uracil isosteres
WO2018098207A1 (en) 2016-11-23 2018-05-31 Cv6 Therapeutics (Ni) Limited Hydantoin containing deoxyuridine triphosphatase inhibitors
US10829457B2 (en) 2016-11-23 2020-11-10 Cv6 Therapeutics (Ni) Limited Nitrogen ring linked deoxyuridine triphosphatase inhibitors
WO2018098206A1 (en) 2016-11-23 2018-05-31 Cv6 Therapeutics (Ni) Limited Hydantoin containing deoxyuridine triphosphatase inhibitors
US11247984B2 (en) 2017-01-05 2022-02-15 Cv6 Therapeutics (Ni) Limited Uracil containing compounds

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1240700B (de) * 1960-10-31 1967-05-18 Eastman Kodak Co Duesentreibstoffe
NL273690A (da) * 1961-01-19 1900-01-01
GB1234935A (en) * 1967-07-03 1971-06-09 Nat Res Dev Piperazine derivatives
NL163957C (nl) * 1968-07-02 1980-11-17 Nat Res Dev Werkwijze voor het bereiden van een geneesmiddel tegen kanker, alsmede werkwijze voor het bereiden van een 1,2-di(3,5-dioxopiperazinoalkaanverbinding.
DE2511891A1 (de) * 1975-03-19 1976-10-07 Gruenenthal Chemie Neue derivate des 2,6-dioxopiperazins, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel sowie verfahren zu deren herstellung
US4404381A (en) * 1981-06-19 1983-09-13 The Dow Chemical Company Novel 3,5-diketo-piperazinyl compounds containing epoxide substituted imides
US4737497A (en) * 1983-04-12 1988-04-12 Zenyaki Kogyo Kabushiki Kaisha Bis-dioxopiperazine derivatives, antitumor agents comprising them and compositions containing them
JPS6097963A (ja) * 1983-10-31 1985-05-31 Zenyaku Kogyo Kk ビス−ジオキソピペラジン誘導体，その製造方法及びそれからなる抗腫瘍剤
US4536564A (en) * 1983-12-09 1985-08-20 The Dow Chemical Company Polyamide from bis-carboxy containing 3,5,3',5'-tetraoxo-1,2-dipiperazine compound and diamine
JPS60152660A (ja) * 1984-01-23 1985-08-10 Nisshin Steel Co Ltd 高硬度マルテンサイト系析出硬化型ステンレス鋼材の製造方法
JPS61152660A (ja) * 1984-12-26 1986-07-11 Zenyaku Kogyo Kk ビス−ジオキソピペラジン誘導体
JPH0676392B2 (ja) * 1985-06-26 1994-09-28 全薬工業株式会社 ビス−ジオキソピペラジン誘導体及びそれからなる抗腫瘍剤
US4764614A (en) * 1987-03-23 1988-08-16 Monsanto Company Process for preparing (S)(+)-4,4'(methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)
JPH0697963A (ja) * 1992-07-02 1994-04-08 Oki Electric Ind Co Ltd パケット交換システム

Also Published As

Publication number Publication date
DK484787A (da) 1987-09-15
EP0256137B1 (en) 1992-12-23
DE3783176D1 (de) 1993-02-04
EP0256137A4 (en) 1989-01-19
DE3783176T2 (de) 1993-04-22
NO874197L (no) 1987-12-07
WO1987004707A1 (en) 1987-08-13
DK484787D0 (da) 1987-09-15
DK156831B (da) 1989-10-09
JPS62281870A (ja) 1987-12-07
NO874197D0 (no) 1987-10-07
JPH0674251B2 (ja) 1994-09-21
AU7025587A (en) 1987-08-25
CA1305484C (en) 1992-07-21
US4868303A (en) 1989-09-19
DK156831C (da) 1990-03-19
NO173604B (no) 1993-09-27
EP0256137A1 (en) 1988-02-24
AU602332B2 (en) 1990-10-11

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Legal Events

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MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN AUGUST 2002