NO874197L - Bis-dioksopiperazinderivater. - Google Patents
Bis-dioksopiperazinderivater.Info
- Publication number
- NO874197L NO874197L NO87874197A NO874197A NO874197L NO 874197 L NO874197 L NO 874197L NO 87874197 A NO87874197 A NO 87874197A NO 874197 A NO874197 A NO 874197A NO 874197 L NO874197 L NO 874197L
- Authority
- NO
- Norway
- Prior art keywords
- dioxopiperazine
- bis
- bis dioxopiperazine
- Prior art date
Links
- JTHRRMFZHSDGNJ-UHFFFAOYSA-N piperazine-2,3-dione Chemical compound O=C1NCCNC1=O JTHRRMFZHSDGNJ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2519186 | 1986-02-07 | ||
PCT/JP1987/000074 WO1987004707A1 (en) | 1986-02-07 | 1987-02-05 | Bis-dioxopiperazine derivatives |
CA000536472A CA1305484C (en) | 1986-02-07 | 1987-05-06 | Bis-dioxopiperazine derivatives and process for preparation thereof |
Publications (4)
Publication Number | Publication Date |
---|---|
NO874197D0 NO874197D0 (no) | 1987-10-07 |
NO874197L true NO874197L (no) | 1987-12-07 |
NO173604B NO173604B (no) | 1993-09-27 |
NO173604C NO173604C (no) | 1994-01-05 |
Family
ID=25671332
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO874197A NO173604C (no) | 1986-02-07 | 1987-10-07 | Analogifremgangsmaate til fremstilling av bis-dioksopiperazinderivater |
Country Status (8)
Country | Link |
---|---|
US (1) | US4868303A (no) |
EP (1) | EP0256137B1 (no) |
JP (1) | JPH0674251B2 (no) |
CA (1) | CA1305484C (no) |
DE (1) | DE3783176T2 (no) |
DK (1) | DK156831C (no) |
NO (1) | NO173604C (no) |
WO (1) | WO1987004707A1 (no) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3050598B2 (ja) * | 1990-07-04 | 2000-06-12 | 全薬工業株式会社 | 水溶性ビスージオキソピペラジン誘導体 |
WO1993008288A1 (en) * | 1991-10-23 | 1993-04-29 | Cancer Research Campaign Technology Limited | Bacterial nitroreductase for the reduction of cb 1954 and analogues thereof to a cytotoxic form |
WO2014107622A1 (en) | 2013-01-07 | 2014-07-10 | University Of Southern California | Deoxyuridine triphosphatase inhibitors |
JP6513095B2 (ja) * | 2014-01-03 | 2019-05-15 | ユニバーシティ オブ サザン カリフォルニア | ヘテロ原子含有デオキシウリジントリホスファターゼ阻害剤 |
US10577321B2 (en) | 2015-07-08 | 2020-03-03 | University Of Southern California | Deoxyuridine triphosphatase inhibitors |
US10544105B2 (en) | 2015-07-08 | 2020-01-28 | Cv6 Therapeutics (Ni) Limited | Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage |
EP3319939A1 (en) | 2015-07-08 | 2018-05-16 | CV6 Therapeutics (NI) Limited | Hydantoin containing deoxyuridine triphosphatase inhibitors |
WO2017006271A1 (en) | 2015-07-08 | 2017-01-12 | University Of Southern California | Deoxyuridine triphosphatase inhibitors containing amino sulfonyl linkage |
US11168059B2 (en) | 2016-11-23 | 2021-11-09 | Cv6 Therapeutics (Ni) Limited | Amino sulfonyl compounds |
US11174271B2 (en) | 2016-11-23 | 2021-11-16 | Cv6 Therapeutics (Ni) Limited | 6-membered uracil isosteres |
WO2018098207A1 (en) | 2016-11-23 | 2018-05-31 | Cv6 Therapeutics (Ni) Limited | Hydantoin containing deoxyuridine triphosphatase inhibitors |
US10829457B2 (en) | 2016-11-23 | 2020-11-10 | Cv6 Therapeutics (Ni) Limited | Nitrogen ring linked deoxyuridine triphosphatase inhibitors |
WO2018098206A1 (en) | 2016-11-23 | 2018-05-31 | Cv6 Therapeutics (Ni) Limited | Hydantoin containing deoxyuridine triphosphatase inhibitors |
US11247984B2 (en) | 2017-01-05 | 2022-02-15 | Cv6 Therapeutics (Ni) Limited | Uracil containing compounds |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1240700B (de) * | 1960-10-31 | 1967-05-18 | Eastman Kodak Co | Duesentreibstoffe |
NL273690A (no) * | 1961-01-19 | 1900-01-01 | ||
GB1234935A (en) * | 1967-07-03 | 1971-06-09 | Nat Res Dev | Piperazine derivatives |
NL163957C (nl) * | 1968-07-02 | 1980-11-17 | Nat Res Dev | Werkwijze voor het bereiden van een geneesmiddel tegen kanker, alsmede werkwijze voor het bereiden van een 1,2-di(3,5-dioxopiperazinoalkaanverbinding. |
DE2511891A1 (de) * | 1975-03-19 | 1976-10-07 | Gruenenthal Chemie | Neue derivate des 2,6-dioxopiperazins, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel sowie verfahren zu deren herstellung |
US4404381A (en) * | 1981-06-19 | 1983-09-13 | The Dow Chemical Company | Novel 3,5-diketo-piperazinyl compounds containing epoxide substituted imides |
US4737497A (en) * | 1983-04-12 | 1988-04-12 | Zenyaki Kogyo Kabushiki Kaisha | Bis-dioxopiperazine derivatives, antitumor agents comprising them and compositions containing them |
JPS6097963A (ja) * | 1983-10-31 | 1985-05-31 | Zenyaku Kogyo Kk | ビス−ジオキソピペラジン誘導体,その製造方法及びそれからなる抗腫瘍剤 |
US4536564A (en) * | 1983-12-09 | 1985-08-20 | The Dow Chemical Company | Polyamide from bis-carboxy containing 3,5,3',5'-tetraoxo-1,2-dipiperazine compound and diamine |
JPS60152660A (ja) * | 1984-01-23 | 1985-08-10 | Nisshin Steel Co Ltd | 高硬度マルテンサイト系析出硬化型ステンレス鋼材の製造方法 |
JPS61152660A (ja) * | 1984-12-26 | 1986-07-11 | Zenyaku Kogyo Kk | ビス−ジオキソピペラジン誘導体 |
JPH0676392B2 (ja) * | 1985-06-26 | 1994-09-28 | 全薬工業株式会社 | ビス−ジオキソピペラジン誘導体及びそれからなる抗腫瘍剤 |
US4764614A (en) * | 1987-03-23 | 1988-08-16 | Monsanto Company | Process for preparing (S)(+)-4,4'(methyl-1,2-ethanediyl)-bis(2,6-piperazinedione) |
JPH0697963A (ja) * | 1992-07-02 | 1994-04-08 | Oki Electric Ind Co Ltd | パケット交換システム |
-
1987
- 1987-02-04 JP JP62024348A patent/JPH0674251B2/ja not_active Expired - Lifetime
- 1987-02-05 WO PCT/JP1987/000074 patent/WO1987004707A1/ja active IP Right Grant
- 1987-02-05 EP EP87901122A patent/EP0256137B1/en not_active Expired - Lifetime
- 1987-02-05 DE DE8787901122T patent/DE3783176T2/de not_active Expired - Fee Related
- 1987-02-05 US US07/124,932 patent/US4868303A/en not_active Expired - Fee Related
- 1987-05-06 CA CA000536472A patent/CA1305484C/en not_active Expired - Fee Related
- 1987-09-15 DK DK484787A patent/DK156831C/da not_active IP Right Cessation
- 1987-10-07 NO NO874197A patent/NO173604C/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK484787A (da) | 1987-09-15 |
NO173604C (no) | 1994-01-05 |
EP0256137B1 (en) | 1992-12-23 |
DE3783176D1 (de) | 1993-02-04 |
EP0256137A4 (en) | 1989-01-19 |
DE3783176T2 (de) | 1993-04-22 |
WO1987004707A1 (en) | 1987-08-13 |
DK484787D0 (da) | 1987-09-15 |
DK156831B (da) | 1989-10-09 |
JPS62281870A (ja) | 1987-12-07 |
NO874197D0 (no) | 1987-10-07 |
JPH0674251B2 (ja) | 1994-09-21 |
AU7025587A (en) | 1987-08-25 |
CA1305484C (en) | 1992-07-21 |
US4868303A (en) | 1989-09-19 |
DK156831C (da) | 1990-03-19 |
NO173604B (no) | 1993-09-27 |
EP0256137A1 (en) | 1988-02-24 |
AU602332B2 (en) | 1990-10-11 |
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Legal Events
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---|---|---|---|
MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN AUGUST 2002 |