NO172575C - Analogifremgangsmaate for fremstilling av terapeutisk aktive benzocykloalkanderivater - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk aktive benzocykloalkanderivaterInfo
- Publication number
- NO172575C NO172575C NO902279A NO902279A NO172575C NO 172575 C NO172575 C NO 172575C NO 902279 A NO902279 A NO 902279A NO 902279 A NO902279 A NO 902279A NO 172575 C NO172575 C NO 172575C
- Authority
- NO
- Norway
- Prior art keywords
- benzocyclylkane
- derivatives
- preparation
- therapeutic active
- analogue procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D315/00—Heterocyclic compounds containing rings having one oxygen atom as the only ring hetero atom according to more than one of groups C07D303/00 - C07D313/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
- C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/43—Y being a hetero atom
- C07C323/44—X or Y being nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/12—One of the condensed rings being a six-membered aromatic ring the other ring being at least seven-membered
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13432189 | 1989-05-25 | ||
JP926490 | 1990-01-17 |
Publications (4)
Publication Number | Publication Date |
---|---|
NO902279D0 NO902279D0 (no) | 1990-05-23 |
NO902279L NO902279L (no) | 1990-11-26 |
NO172575B NO172575B (no) | 1993-05-03 |
NO172575C true NO172575C (no) | 1993-08-11 |
Family
ID=26343949
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO902279A NO172575C (no) | 1989-05-25 | 1990-05-23 | Analogifremgangsmaate for fremstilling av terapeutisk aktive benzocykloalkanderivater |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0399422A1 (fr) |
KR (1) | KR900018065A (fr) |
CN (1) | CN1047859A (fr) |
AU (1) | AU632809B2 (fr) |
CA (1) | CA2017444A1 (fr) |
FI (1) | FI902597A0 (fr) |
HU (1) | HU206195B (fr) |
IL (1) | IL94450A0 (fr) |
NO (1) | NO172575C (fr) |
NZ (1) | NZ233790A (fr) |
PT (1) | PT94158A (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2068497T3 (es) * | 1990-03-12 | 1995-04-16 | Yamanouchi Pharma Co Ltd | Derivados de urea, su produccion, y composiciones farmaceuticas que los contienen. |
US5401848A (en) * | 1990-11-26 | 1995-03-28 | E. R. Squibb & Sons, Inc. | Indane and quinoline derivatives |
IL100915A (en) * | 1991-02-19 | 1996-03-31 | Erba Carlo Spa | Double-transformed urea and theories, their preparation and pharmaceutical preparations containing them |
US5420164A (en) * | 1991-04-04 | 1995-05-30 | Yoshitomi Pharmaceutical Industries, Ltd. | Cycloalkylurea compounds |
IL101785A0 (en) * | 1991-05-10 | 1992-12-30 | Fujisawa Pharmaceutical Co | Urea derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
CA2134359C (fr) * | 1992-05-28 | 1997-07-01 | Ernest S. Hamanaka | Nouveaux derives n-aryliques et n-heteroaryluree utilises comme inhibiteurs de l'acyl-coa : cholesterol acyltransferase |
NZ250916A (en) * | 1993-02-27 | 1995-08-28 | Nihon Nohyaku Co Ltd | N-heteroaryl-n'-phenylureas, their use as acat inhibitors |
ES2076865B1 (es) * | 1993-07-05 | 1996-08-01 | Pfizer | Nuevos derivados de n-aril- y n-heteroaril-urea como inhibidores de acil-coenzima a: colesterol acil transferasa (acat). |
DE4401893A1 (de) * | 1994-01-24 | 1995-07-27 | Bayer Ag | Substituierte Arylharnstoffe |
US6133326A (en) | 1994-08-31 | 2000-10-17 | Pfizer Inc | Compositions and methods for decreasing sebum production |
WO1996010559A1 (fr) * | 1994-10-04 | 1996-04-11 | Fujisawa Pharmaceutical Co., Ltd. | Derives d'uree et leur utilisation comme inhibiteurs de l'acat |
GB9913083D0 (en) | 1999-06-04 | 1999-08-04 | Novartis Ag | Organic compounds |
AP2002002612A0 (en) | 2000-02-02 | 2002-09-30 | Warner Lambert Co | Dual inhibitors of cholesterol ester and wax ester synthesis for sebaceous gland disorders |
TWI243164B (en) | 2001-02-13 | 2005-11-11 | Aventis Pharma Gmbh | Acylated indanyl amines and their use as pharmaceuticals |
PT1554240E (pt) * | 2002-10-21 | 2009-06-17 | Janssen Pharmaceutica Nv | Tetralinas e indanos substituídos e sua utilização |
JP2006503915A (ja) * | 2002-10-21 | 2006-02-02 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 置換テトラリンおよびインダンを用いたx症候群の治療 |
CN100349864C (zh) * | 2002-10-21 | 2007-11-21 | 詹森药业有限公司 | 取代的四氢化萘和茚满及其应用 |
AR048931A1 (es) | 2004-04-21 | 2006-06-14 | Janssen Pharmaceutica Nv | Proceso para la preparacion de derivados de tetralina sustituida e indano sustituido y preparacion de intermediarios de sintesis |
AU2010301449B2 (en) * | 2009-09-30 | 2013-03-14 | Toray Industries, Inc. | 2,3-dihydro-1H-indene-2-ylurea derivative and pharmaceutical application of same |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1479544A (en) * | 1974-02-07 | 1977-07-13 | American Cyanamid Co | 1,2,3,4-tetrahydro-1-naphthylurea derivatives their preparation and their use |
NZ180693A (en) * | 1975-05-30 | 1978-06-20 | American Cyanamid Co | 1,2,3,4-tetrahydro-4-oxo(oroxy)-1-naphthylurea derivatives,veterinary compositions containing them and the 1,2,3,4 tetrahydro-4-oxo-1-naphthylamine precursors |
BE854046A (fr) * | 1976-05-04 | 1977-10-28 | Scherico Ltd | Arylurees substituees, leur procede de preparation et compositions pharmaceutiques en contenant |
US4623662A (en) * | 1985-05-23 | 1986-11-18 | American Cyanamid Company | Antiatherosclerotic ureas and thioureas |
ES2068497T3 (es) * | 1990-03-12 | 1995-04-16 | Yamanouchi Pharma Co Ltd | Derivados de urea, su produccion, y composiciones farmaceuticas que los contienen. |
-
1990
- 1990-05-18 AU AU55188/90A patent/AU632809B2/en not_active Ceased
- 1990-05-19 EP EP19900109570 patent/EP0399422A1/fr not_active Ceased
- 1990-05-20 IL IL94450A patent/IL94450A0/xx unknown
- 1990-05-23 NZ NZ233790A patent/NZ233790A/xx unknown
- 1990-05-23 NO NO902279A patent/NO172575C/no unknown
- 1990-05-24 FI FI902597A patent/FI902597A0/fi not_active IP Right Cessation
- 1990-05-24 CA CA002017444A patent/CA2017444A1/fr not_active Abandoned
- 1990-05-25 KR KR1019900007621A patent/KR900018065A/ko not_active Application Discontinuation
- 1990-05-25 CN CN90103797A patent/CN1047859A/zh active Pending
- 1990-05-25 PT PT94158A patent/PT94158A/pt not_active Application Discontinuation
- 1990-05-25 HU HU903196A patent/HU206195B/hu not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT94158A (pt) | 1991-01-08 |
HUT54112A (en) | 1991-01-28 |
HU903196D0 (en) | 1990-10-28 |
CN1047859A (zh) | 1990-12-19 |
NO902279D0 (no) | 1990-05-23 |
HU206195B (en) | 1992-09-28 |
KR900018065A (ko) | 1990-12-20 |
NZ233790A (en) | 1991-11-26 |
NO902279L (no) | 1990-11-26 |
FI902597A0 (fi) | 1990-05-24 |
NO172575B (no) | 1993-05-03 |
AU632809B2 (en) | 1993-01-14 |
IL94450A0 (en) | 1991-03-10 |
AU5518890A (en) | 1990-11-29 |
EP0399422A1 (fr) | 1990-11-28 |
CA2017444A1 (fr) | 1990-11-25 |
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