NO167924C - Analogifremgangsmaate for fremstilling av terapeutisk aktive thymopentinanaloger - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive thymopentinanaloger

Info

Publication number
NO167924C
NO167924C NO852567A NO852567A NO167924C NO 167924 C NO167924 C NO 167924C NO 852567 A NO852567 A NO 852567A NO 852567 A NO852567 A NO 852567A NO 167924 C NO167924 C NO 167924C
Authority
NO
Norway
Prior art keywords
preparation
therapeutically active
analogy procedure
thymopentin
analogs
Prior art date
Application number
NO852567A
Other languages
English (en)
Norwegian (no)
Other versions
NO852567L (no
NO167924B (no
Inventor
Gideon Goldstein
George Heavner
Daniel Kroon
Tapan Audhya
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of NO852567L publication Critical patent/NO852567L/no
Publication of NO167924B publication Critical patent/NO167924B/no
Publication of NO167924C publication Critical patent/NO167924C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/66Thymopoietins
    • C07K14/662Thymopoietins at least 1 amino acid in D-form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/18Thymus derived hormone or factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Control Of Eletrric Generators (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Control Of Charge By Means Of Generators (AREA)
  • Control Of Combustion (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NO852567A 1984-06-27 1985-06-26 Analogifremgangsmaate for fremstilling av terapeutisk aktive thymopentinanaloger NO167924C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/625,344 US4629723A (en) 1984-06-27 1984-06-27 Potent thymopentin analogs

Publications (3)

Publication Number Publication Date
NO852567L NO852567L (no) 1985-12-30
NO167924B NO167924B (no) 1991-09-16
NO167924C true NO167924C (no) 1991-12-27

Family

ID=24505633

Family Applications (1)

Application Number Title Priority Date Filing Date
NO852567A NO167924C (no) 1984-06-27 1985-06-26 Analogifremgangsmaate for fremstilling av terapeutisk aktive thymopentinanaloger

Country Status (14)

Country Link
US (2) US4629723A (fr)
EP (1) EP0166612B1 (fr)
JP (1) JPH0689029B2 (fr)
KR (1) KR920006563B1 (fr)
AT (1) ATE81135T1 (fr)
AU (1) AU592309B2 (fr)
CA (1) CA1269499A (fr)
DE (1) DE3586697T2 (fr)
DK (1) DK171238B1 (fr)
FI (1) FI92325C (fr)
IL (1) IL75637A (fr)
NO (1) NO167924C (fr)
NZ (1) NZ212461A (fr)
ZA (1) ZA854832B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU602483B2 (en) * 1985-01-18 1990-10-18 Immunetech Pharmaceuticals Immunoregulatory peptides
DE3619633A1 (de) * 1986-06-11 1987-12-17 Hoechst Ag Peptide mit einfluss auf die diurese und natriurese, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
HUT46044A (en) * 1986-11-21 1988-09-28 Richter Gedeon Vegyeszet Process for producing immunstimulant peptides inhibiting multiplication of leukaemic cells and pharmaceutics comprising same
IT1216908B (it) * 1987-03-19 1990-03-14 Eniricerche Spa Analoghi retro-inversi della timopentina e dei suoi frammenti, il metodo per la loro sintesi ed il loro impiego per la preparazionedi composizioni farmaceutiche.
HU199878B (en) * 1987-06-19 1990-03-28 Berlin Chemie Veb Process for producing acylated splenopentynes and pharmaceutical compositions comprising such compounds as active ingredient
US5656601A (en) * 1987-06-19 1997-08-12 Berlin-Chemie Ag Acylated splenopentins, methods for their synthesis and their use
JPH01125328A (ja) * 1987-07-30 1989-05-17 Centro Natl De Biopreparados 髄膜炎菌ワクチン
WO1989009229A1 (fr) * 1988-03-31 1989-10-05 Immunobiology Research Institute, Inc. Traitement de patient atteint de viremie du hiv a l'aide de thymopentine
NZ229004A (en) * 1988-05-19 1993-09-27 Immunobiology Res Inst Inc Tetrapeptides having t cell helper acitivity
US4943477A (en) * 1988-09-27 1990-07-24 Mitsubishi Rayon Co., Ltd. Conductive sheet having electromagnetic interference shielding function
HU205143B (en) * 1988-09-30 1992-03-30 Immunobiology Res Inst Inc Process for producing peptides having t cell suppressor activity and pharmaceutical compositions comprising same
US5218089A (en) * 1988-12-23 1993-06-08 Sclavo S.P.A. Retro-inverso analogues of thymopentin and the method for their synthesis
IT1227908B (it) * 1988-12-23 1991-05-14 Eniricerche S P A Milano Sclav Nuovi analoghi retro-inversi della timopentina, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche
US5036050A (en) * 1989-01-12 1991-07-30 Immunobiology Research Institute, Inc. Compositions containing thymopentin for topical treatment of skin disorders
JPH06506918A (ja) * 1991-02-04 1994-08-04 ジヨージ・ワシントン・ユニバーシテイ インターロイキン−1の産生を促進しそして年令−関連性免疫応答を調整するペプチドmb−4
US5492894A (en) * 1991-03-21 1996-02-20 The Procter & Gamble Company Compositions for treating wrinkles comprising a peptide
US5215964A (en) * 1991-06-03 1993-06-01 Immunobiology Research Institute, Inc. Peptides useful in regulating the immune and nervous systems
US5952465A (en) * 1993-04-23 1999-09-14 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
CA2161108A1 (fr) * 1993-04-23 1994-11-10 Herbert J. Evans Polypeptides avec groupes exercant une contrainte sur la conformation, a cote d'un site d'interaction proteine-proteine
US5965698A (en) * 1993-04-23 1999-10-12 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US5928896A (en) * 1993-04-23 1999-07-27 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US6258550B1 (en) 1993-04-23 2001-07-10 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5639729A (en) * 1993-08-26 1997-06-17 Immunobiology Research Institute, Inc. Tripeptides useful in immune and CNS therapy
US6084066A (en) * 1993-10-29 2000-07-04 Virginia Commonwealth University Polypetides that include conformation-constraining groups which flank a protein-protein interaction site
FR2741076B1 (fr) 1995-11-15 1998-01-30 Rech De Pathologie Appliquee S Conjugues peptidiques derives des hormones thymiques, leur utilisation a titre de medicament et compositions les contenant
CN101168560B (zh) * 2006-10-23 2012-09-05 江苏正大天晴药业股份有限公司 N-取代肽酰胺,其药物组合物与用途
CN116712571B (zh) * 2021-12-16 2024-01-30 江西中医药大学 一种新型环肽在制备肿瘤诊断和或治疗试剂中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4077949A (en) * 1973-12-28 1978-03-07 Sloan-Kettering Institute For Cancer Research Polypeptide hormones of the thymus
US4002740A (en) * 1975-08-21 1977-01-11 Gideon Goldstein Tridecapeptide compositions and methods
US4190646A (en) * 1975-11-11 1980-02-26 Sloan-Kettering Institute For Cancer Research Polypeptide compositions and methods
SE446867B (sv) * 1977-11-15 1986-10-13 Sloan Kettering Inst Cancer Sett att framstella en polypeptid med formaga att inducera differentiering av t-lymfocyter men inte av komplementreceptor (cr?72+) b-lymfocyter
ZA802170B (en) * 1979-04-12 1981-11-25 Ortho Pharma Corp Peptides having thymopoietin-like activity
CA1157466A (fr) * 1979-04-12 1983-11-22 Gideon Goldstein Peptides ayant des proprietes ressemblant a celles de la thymopoietine
US4261886A (en) * 1980-03-13 1981-04-14 Ortho Pharmaceutical Corporation Peptides having thymopoietin-like activity
DE2938420A1 (de) * 1979-09-22 1981-04-09 Hoechst Ag, 6000 Frankfurt Neue peptide und verfahren zu ihrer herstellung
US4309340A (en) * 1980-03-31 1982-01-05 American Home Products Corporation Polypeptide compositions
US4361673A (en) * 1980-09-19 1982-11-30 American Home Products Corporation Polypeptide compositions
US4305852A (en) * 1980-10-20 1981-12-15 American Home Products Corporation Polypeptide compositions
US4505853A (en) * 1983-11-18 1985-03-19 Ortho Pharmaceutical Corporation Enzyme-resistant immunomodulatory peptides
DE3421614A1 (de) * 1984-06-09 1985-12-12 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von pentapeptiden mit wirkung auf das immunsystem und zwischenprodukte dieses verfahrens

Also Published As

Publication number Publication date
DE3586697D1 (en) 1992-11-05
USRE34165E (en) 1993-01-19
KR860000314A (ko) 1986-01-28
JPS6118799A (ja) 1986-01-27
IL75637A (en) 1990-02-09
AU4421585A (en) 1986-01-02
NZ212461A (en) 1988-10-28
CA1269499A (fr) 1990-05-22
IL75637A0 (en) 1985-10-31
US4629723A (en) 1986-12-16
DK289285D0 (da) 1985-06-26
FI92325B (fi) 1994-07-15
DK171238B1 (da) 1996-08-05
AU592309B2 (en) 1990-01-11
JPH0689029B2 (ja) 1994-11-09
EP0166612B1 (fr) 1992-09-30
NO852567L (no) 1985-12-30
FI92325C (fi) 1994-10-25
DK289285A (da) 1985-12-28
FI852522A0 (fi) 1985-06-26
ZA854832B (en) 1987-02-25
NO167924B (no) 1991-09-16
EP0166612A2 (fr) 1986-01-02
EP0166612A3 (en) 1987-08-05
KR920006563B1 (ko) 1992-08-08
FI852522L (fi) 1985-12-28
ATE81135T1 (de) 1992-10-15
DE3586697T2 (de) 1993-02-11

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