NO166642C - Anaolgifremgangsmaate for fremstilling av terapeutisk aktive 3-aryl-5-alkylthio-4h-1,2,4-triazoler. - Google Patents

Anaolgifremgangsmaate for fremstilling av terapeutisk aktive 3-aryl-5-alkylthio-4h-1,2,4-triazoler.

Info

Publication number
NO166642C
NO166642C NO880337A NO880337A NO166642C NO 166642 C NO166642 C NO 166642C NO 880337 A NO880337 A NO 880337A NO 880337 A NO880337 A NO 880337A NO 166642 C NO166642 C NO 166642C
Authority
NO
Norway
Prior art keywords
anaological
triazoles
alkylthio
aryl
procedure
Prior art date
Application number
NO880337A
Other languages
English (en)
Norwegian (no)
Other versions
NO880337D0 (no
NO880337L (no
NO166642B (no
Inventor
John M Kane
Francis P Miller
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO880337D0 publication Critical patent/NO880337D0/no
Publication of NO880337L publication Critical patent/NO880337L/no
Publication of NO166642B publication Critical patent/NO166642B/no
Publication of NO166642C publication Critical patent/NO166642C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO880337A 1987-01-27 1988-01-26 Anaolgifremgangsmaate for fremstilling av terapeutisk aktive 3-aryl-5-alkylthio-4h-1,2,4-triazoler. NO166642C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US706387A 1987-01-27 1987-01-27
US07/126,191 US4900743A (en) 1987-01-27 1987-12-04 3-aryl-5-alkylthio-4H-1,2,4-triazoles

Publications (4)

Publication Number Publication Date
NO880337D0 NO880337D0 (no) 1988-01-26
NO880337L NO880337L (no) 1988-07-28
NO166642B NO166642B (no) 1991-05-13
NO166642C true NO166642C (no) 1991-08-21

Family

ID=26676435

Family Applications (1)

Application Number Title Priority Date Filing Date
NO880337A NO166642C (no) 1987-01-27 1988-01-26 Anaolgifremgangsmaate for fremstilling av terapeutisk aktive 3-aryl-5-alkylthio-4h-1,2,4-triazoler.

Country Status (19)

Country Link
US (1) US4900743A (de)
EP (1) EP0276793B1 (de)
JP (1) JP2537651B2 (de)
KR (1) KR960007166B1 (de)
CN (1) CN1023480C (de)
AR (1) AR244682A1 (de)
AU (1) AU601013B2 (de)
CA (1) CA1312605C (de)
DE (1) DE3881712T2 (de)
DK (1) DK171599B1 (de)
ES (1) ES2058144T3 (de)
FI (1) FI91526C (de)
HU (1) HU205747B (de)
IE (1) IE61188B1 (de)
IL (1) IL85185A (de)
NO (1) NO166642C (de)
NZ (1) NZ223260A (de)
PH (1) PH24513A (de)
PT (1) PT86623B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2948189A (en) * 1987-12-31 1989-08-01 Smithkline Beckman Corporation 4-aralkyl-5-substituted-1,2,4-triazole-5-thiols
AU644500B2 (en) * 1990-12-20 1993-12-09 Merrell Dow Pharmaceuticals Inc. 3-aryl-5-alkylthio-4h-1,2,4-triazoles for treatment of hyperreflexia due to spinal trauma
DE4339412A1 (de) * 1993-11-18 1995-05-24 Bayer Ag Verfahren und neue Zwischenprodukte zur Herstellung von Triazolinonen
AR032653A1 (es) 2001-02-09 2003-11-19 Telik Inc Inhibidores heterociclicos del trasportador de glicina 2 composiciones farmaceuticas, uso y metodos.
CN1736381B (zh) * 2005-08-11 2010-09-08 沈阳药科大学 吗啉甲基萘满酮用于制备平滑肌解痉剂的用途
EP2376474A4 (de) * 2008-12-12 2012-07-04 Astrazeneca Ab Neues verfahren zur herstellung von 4-[4-methyl-5-(c1-10-alkylthio/c5-10-aryl-c1-6-alkylthio)-4h-1,2,4-triazol-2-yl]pyridinen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU193891B (en) * 1984-02-07 1987-12-28 Gyogyszerkutato Intezet Process for production of new derivatives of 1,2,4-triasole

Also Published As

Publication number Publication date
PT86623B (pt) 1993-01-29
EP0276793B1 (de) 1993-06-16
AU601013B2 (en) 1990-08-30
NO880337D0 (no) 1988-01-26
IL85185A0 (en) 1988-07-31
NO880337L (no) 1988-07-28
EP0276793A3 (en) 1988-09-21
CA1312605C (en) 1993-01-12
HUT47257A (en) 1989-02-28
PH24513A (en) 1990-07-18
KR960007166B1 (ko) 1996-05-29
IL85185A (en) 1996-03-31
FI91526C (fi) 1994-07-11
NO166642B (no) 1991-05-13
HU205747B (en) 1992-06-29
AR244682A1 (es) 1993-11-30
CN1023480C (zh) 1994-01-12
ES2058144T3 (es) 1994-11-01
FI880282A0 (fi) 1988-01-22
KR880008999A (ko) 1988-09-13
JPS63201176A (ja) 1988-08-19
DE3881712D1 (de) 1993-07-22
DK35488A (da) 1988-07-28
DK171599B1 (da) 1997-02-17
IE61188B1 (en) 1994-10-19
DE3881712T2 (de) 1993-12-23
FI880282A (fi) 1988-07-28
FI91526B (fi) 1994-03-31
DK35488D0 (da) 1988-01-26
NZ223260A (en) 1991-07-26
CN88100346A (zh) 1988-11-02
US4900743A (en) 1990-02-13
JP2537651B2 (ja) 1996-09-25
EP0276793A2 (de) 1988-08-03
PT86623A (pt) 1988-02-01
AU1072888A (en) 1988-07-28

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