NO164097B - Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-(n-substituert-guanidino)-4-hetero-aryl-tiazol-derivater. - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-(n-substituert-guanidino)-4-hetero-aryl-tiazol-derivater. Download PDFInfo
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- NO164097B NO164097B NO851695A NO851695A NO164097B NO 164097 B NO164097 B NO 164097B NO 851695 A NO851695 A NO 851695A NO 851695 A NO851695 A NO 851695A NO 164097 B NO164097 B NO 164097B
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- 238000000034 method Methods 0.000 title claims description 9
- -1 N-SUBSTITUTED-GUANIDINO Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 238000009413 insulation Methods 0.000 claims description 52
- 230000007704 transition Effects 0.000 claims description 11
- 238000004804 winding Methods 0.000 claims description 11
- 239000004020 conductor Substances 0.000 claims description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical group [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 239000012774 insulation material Substances 0.000 description 1
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
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- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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Description
Fremgangsmåte for isolering av staver eller spoler for høyspennings-statorviklinger.
Den foreliggende oppfinnelse vedrorer en fremgangsmåte for isolering av staver eller spoler i hoyspenningsstatorviklinger som såvel i spordelen som i viklingshodedelen er forsynt med båndisolasjon.
Av hoyspennings-statorviklinger forlanges en korrekt dimen-sjonert, tett isolasjon med stor elektrisk fasthet i spordelen. Til boyleforbindelsene for hodedelene på begge sider stilles vanligvis mindre strenge krav i så henseende. Det er kjent to fremgangsmåter for fremstilling av slike isolasjoner.
Ifolge den ene anbringes den i tallrike lag overlappende påviklede isolasjon gjennomgående og på samme måte i spordelen som i hodedelen. Om onsket, kan lagantallet og dermed isola-sjonens tykkelse gjores forskjellig for viklehodet og spordelen. Denne isolasjonstype kalles en likeformet, gjennomgående viklet isolasjon.
I det annet tilfelle anbringes spordelens og boylens isolasjoner hver for seg, og det kan benyttes forskjellige isolasjonsmateri-aler eller anbringelsesmetoder for de to deler. Det er således meget alminnelig å vikle en passende folie i en bred bane på spordelens lederbunt og presse den således dannede hylse fast under trykk- og eventuelt varmepåvirkning. For hodedelene kan det på grunn av boylens krumning bare benyttes båndisolasjon.
En således fremstilt isolasjon betegnes som ikke likeformet (diskontinuerlig) isolasjon. For ikke å forringe den elektriske sikkerhet på grunn av skjotene mellom spor- og boyleisolasjon, er det vanlig å gjore spordelens isolasjon lengre og påforé
den et godt stykke over statorens jerndel. På den koniske avslutning av spordelens isolasjon vikles så hodets båndisolasjon.
Et formål med den foreliggende oppfinnelse er å tilveiebringe
en hoy elektrisk fasthet i overgangen mellom spordelens og hodedelens isolasjon.
Dette oppnås ifolge oppfinnelsen ved at vekselvis er lederbuntens spordel henholdsvis hodedel omviklet med et sjikt av en adskilt båndisolasjon for innbyrdes forskyvning av overgangsstedet mellom de to isolasjoner fra sjikt til sjikt.
På denne måte vil det ved anbringelsen av isolasjonen på staven hhv. spolen overhodet ikke oppstå noe egentlig skjotested mellom de to isolasjoner, men hele isolasjonen forloper praktisk talt likeformet og kontinuerlig. Begge isolasjoner anbringes med en viss overdekking av sjiktene.
Oppfinnelsen skal beskrives nærmere under henvisning til tegningen, hvorpå figuren viser en del av en stav for en statorvikling i lengdesnitt. Stavens isolasjon utfores ifolge oppfinnelsen som folger:
Statorplatenes ende er antydet med b, for at den viklede
stavens stilling i forhold til statoren skal fremgå klart. På lederbunten a vikles forst et lag av et isolasjonsbånd av en eller annen isolasjon frem til det omtrentlige sted hvor overgangen fra den ene isolasjon til den annen skal opprettes, forst f.eks. laget n^ for sporisolasjonen. For bedre oversiktlighets skyld er båndets vindinger her vist kant i kant og ikke overlappende slik det er vanlig å legge dem. Til laget n^ slutter seg det nederste lag c, for boyleisolasjonen. Over dette anbringes lag c ? for bbyleisolasjonen og i tilslutning lag for spordelens isolasjon. På lignende måte anbringes derefter ytterligere lag n^, n^ m.v. for sporisolasjonen og tilsvarende lag c^/ c. m.v. for boyleisolasjonen vekselvis på staven inntil den onskede isolasjonstykkelse er oppnådd. Det må bare påaktes at skjotestedene mellom sporisolasjonens lag og de tilsvarende lag for boyleisolasjonen blir beliggende innenfor området for overgangen. Selvsagt er det også mulig å begynne med samme del av isolasjonen ved hvert nytt båndlag, dvs. å begynne enten med sporisolasjonen eller boyleisolasjonen, i stedet for å skifte som omtalt.
Som det vil fremgå av figuren, kan lagskjotene for de to isolasjoner forskyves i lengderetning fra lag til lag ved anbringelsen av isolasjonsbåndet. På denne måte oppnås enda storre elektrisk fasthet på overgangsstedet mellom de to isolasjoner, og ved bruk av bånd med forskjellig tykkelse for de to isolasjoner fås en jevnere overgang, dvs. man unngår praktisk talt utbukt-ning av isolasjonen på overgangsstedet. Ved bruk av forskjelligartede båndisolasjoner med forskjellig tykkelse for spor- og boyledelen kan det også tilveiebringes en utjevning uten ulemper for den elektriske fasthet på overgangen ved anbringelse av et storre antall lag på den side hvor båndet er tynnere og ved å
la to eller flere lag av samme bånd folge umiddelbart efter hverandre også på overgangsstedet.
Ved den beskrevne fremgangsmåte oppnås en intim overlapping av spordelens og boylens isolasjoner på overgangsstedet mellom de to isolasjoner. Det kan således opprettes en gjennomgående isolasjon for spordelen og viklehodet av statorviklingers staver eller spoler selv om det benyttes forskjelligartede båndisolasjoner for de to deler.
Claims (3)
- Fremgangsmåte for isolering av staver eller spoler i hoyspenningsstatorviklinger som såvel i spordelen som i viklingshodedelen er forsynt med båndisolasjon, karakterisert ved at vekselvis er lederbuntens spordel henholdsvis hodedel omviklet med et sjikt av en adskilt båndisolasjon for innbyrdes forskyvning av overgangsstedet mellom de to isolasjoner fra sjikt til sjikt.
- 2. Fremgangsmåte som angitt i krav 1, karakterisert ved at det for de to isoleringer anvendes bånd med forskjellige tykkelser.
- 3. Fremgangsmåte som angitt i krav 1, karakterisert ved at det for de to isoleringer anvendes bånd med samme tykkelse.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/605,510 US4560690A (en) | 1984-04-30 | 1984-04-30 | 2-(N-substituted guanidino)-4-hetero-arylthiazole antiulcer agents |
Publications (3)
Publication Number | Publication Date |
---|---|
NO851695L NO851695L (no) | 1985-10-31 |
NO164097B true NO164097B (no) | 1990-05-21 |
NO164097C NO164097C (no) | 1990-08-29 |
Family
ID=24423963
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO851695A NO164097C (no) | 1984-04-30 | 1985-04-29 | Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-(n-substituert-guanidino)-4-hetero-aryl-tiazol-derivater. |
Country Status (26)
Country | Link |
---|---|
US (1) | US4560690A (no) |
EP (1) | EP0161841B1 (no) |
JP (1) | JPS60239474A (no) |
KR (1) | KR870000925B1 (no) |
AR (1) | AR241784A1 (no) |
AU (1) | AU554271B2 (no) |
CA (1) | CA1262352A (no) |
CS (2) | CS248750B2 (no) |
DD (1) | DD233374A5 (no) |
DE (1) | DE3571618D1 (no) |
DK (1) | DK165693C (no) |
EG (1) | EG17391A (no) |
ES (2) | ES8605511A1 (no) |
FI (1) | FI81096C (no) |
GR (1) | GR851020B (no) |
HU (1) | HU198300B (no) |
IL (1) | IL75038A (no) |
IN (1) | IN165501B (no) |
NO (1) | NO164097C (no) |
NZ (1) | NZ211909A (no) |
PH (1) | PH21824A (no) |
PL (2) | PL146070B1 (no) |
PT (1) | PT80361B (no) |
SU (2) | SU1380614A3 (no) |
YU (2) | YU43977B (no) |
ZA (1) | ZA853161B (no) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
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WO1986003203A1 (en) * | 1984-11-22 | 1986-06-05 | Yoshitomi Pharmaceutical Industries, Ltd. | Thienylthiazole derivatives |
US5001138B1 (en) * | 1985-02-04 | 1998-01-20 | Bayer Agrochem Kk | Heterocyclic compounds |
EP0192060B1 (de) * | 1985-02-04 | 1991-09-18 | Nihon Bayer Agrochem K.K. | Heterocyclische Verbindungen |
DE3772301D1 (de) * | 1986-08-29 | 1991-09-26 | Pfizer | 2-guanidino-4-aryl-thiazole fuer die behandlung von peptischen geschwueren. |
US4997981A (en) * | 1986-10-29 | 1991-03-05 | Pfizer Inc. | Processes for 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl) thiazole and analogs |
US4997949A (en) * | 1986-10-29 | 1991-03-05 | Pfizer Inc. | Crystalline 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl) thiazole dihydrochloride trihydrate |
DE3750023T2 (de) * | 1986-10-29 | 1994-09-29 | Pfizer, Inc., New York, N.Y. | Verfahren zur Herstellung von 2-(1-Pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)Thiazol und dessen kristallinisches Dihydrochlorid-Trihydrat. |
DE3715704A1 (de) * | 1987-05-12 | 1988-11-24 | Bayer Ag | Ss-fluoracyl-ss-halogenvinylalkylether |
ES2030974T3 (es) * | 1988-07-21 | 1992-11-16 | Pfizer Inc. | Proceso de preparado de sustitutos de guaniltioureas. |
IL91152A0 (en) * | 1988-08-15 | 1990-03-19 | Fujisawa Pharmaceutical Co | Furylthiazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
WO1990002127A1 (en) * | 1988-08-30 | 1990-03-08 | Pfizer Inc. | Hemiphosphate hemihydrate of 2-(1-pentyl-3-guanidino-4-imidazolyl)thiazole |
GB8903592D0 (en) * | 1989-02-16 | 1989-04-05 | Boots Co Plc | Therapeutic agents |
IL95548A0 (en) * | 1989-09-15 | 1991-06-30 | Fujisawa Pharmaceutical Co | Thiazole derivatives,processes for the preparation thereof and pharmaceutical composition containing the same |
US4985402A (en) * | 1990-04-25 | 1991-01-15 | International Flavors & Fragrances Inc. | 2-Methyl-1-nitrilo-2-methyl -1-hydroxylamino-3-(methoxyphenyl) propane, organoleptic uses thereof and processes for preparing same |
US5387656A (en) * | 1990-07-23 | 1995-02-07 | Alliedsignal Inc. | Substituted cyanoguanidines as curing agents for epoxy resins |
EP0564479A1 (en) * | 1990-12-24 | 1993-10-13 | Gesellschaft für Biotechnologische Forschung mbH (GBF) | Thiangazole, its preparation, compositions and use thereof |
US5610038A (en) * | 1990-12-24 | 1997-03-11 | Ciba-Geigy Corporation | Thiangazole, its preparation, compositions and use thereof |
US5387597A (en) * | 1991-02-25 | 1995-02-07 | Pfizer Inc. | Hemiphosphate hemihydrate of 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole |
CA2105981A1 (en) * | 1991-03-13 | 1992-09-14 | Hisashi Takasugi | Thiazole derivatives |
JPH08506353A (ja) * | 1993-06-15 | 1996-07-09 | フアイザー・インコーポレイテツド | ウシもしくはブタの細菌感染における免疫刺激剤としてのh2−拮抗剤 |
DK0706514T3 (da) * | 1993-08-24 | 1999-08-02 | Medivir Ab | Forbindelser og fremgangsmåder til inhibering af HIV og relaterede vira |
DE19523658A1 (de) * | 1995-06-29 | 1997-01-02 | Bayer Ag | Substituierte N-Methylenthioharnstoffe |
SI0928793T1 (en) * | 1998-01-02 | 2002-10-31 | F. Hoffmann-La Roche Ag | Thiazole derivatives |
DE102004008141A1 (de) * | 2004-02-19 | 2005-09-01 | Abbott Gmbh & Co. Kg | Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren |
US8895564B2 (en) | 2010-12-02 | 2014-11-25 | Nihon University | Biguanide derivative compound |
EP4196793A1 (en) | 2020-08-11 | 2023-06-21 | Université de Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2455807A (en) * | 1945-09-11 | 1948-12-07 | American Cyanamid Co | Preparation of substituted cyanoguanidine |
IL49528A (en) * | 1975-05-21 | 1980-11-30 | Smith Kline French Lab | Imidazolyl(or thiazolyl)methylthio(or butyl)guanidine or thiourea derivatives,their preparation and pharmaceutical compositions comprising them |
EP0003640B1 (en) * | 1978-01-18 | 1982-01-27 | Imperial Chemical Industries Plc | Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them |
JPS6056143B2 (ja) * | 1979-08-02 | 1985-12-09 | 山之内製薬株式会社 | アミジン誘導体ならびにその製造法 |
GR71929B (no) * | 1979-11-13 | 1983-08-19 | Ici Ltd | |
US4374843A (en) * | 1980-10-14 | 1983-02-22 | Pfizer Inc. | 2-Guanidino-4-heteroarylthiazoles |
US4435396A (en) * | 1982-05-10 | 1984-03-06 | Pfizer Inc. | Antiulcer 2-guanidino-4-(2-substituted-amino-4-imidazolyl)thiazoles and process therefor |
-
1984
- 1984-04-30 US US06/605,510 patent/US4560690A/en not_active Expired - Lifetime
-
1985
- 1985-03-22 IN IN244/DEL/85A patent/IN165501B/en unknown
- 1985-04-24 EP EP85302844A patent/EP0161841B1/en not_active Expired
- 1985-04-24 DE DE8585302844T patent/DE3571618D1/de not_active Expired
- 1985-04-25 CS CS857163A patent/CS248750B2/cs not_active IP Right Cessation
- 1985-04-25 CS CS853042A patent/CS248741B2/cs not_active IP Right Cessation
- 1985-04-26 CA CA000480150A patent/CA1262352A/en not_active Expired
- 1985-04-26 NZ NZ211909A patent/NZ211909A/en unknown
- 1985-04-26 DD DD85275638A patent/DD233374A5/de not_active IP Right Cessation
- 1985-04-26 PL PL1985257845A patent/PL146070B1/pl unknown
- 1985-04-26 PT PT80361A patent/PT80361B/pt not_active IP Right Cessation
- 1985-04-26 PL PL1985253107A patent/PL145213B1/pl unknown
- 1985-04-26 GR GR851020A patent/GR851020B/el unknown
- 1985-04-28 EG EG268/85A patent/EG17391A/xx active
- 1985-04-29 AR AR85300218A patent/AR241784A1/es active
- 1985-04-29 PH PH32200A patent/PH21824A/en unknown
- 1985-04-29 HU HU851646A patent/HU198300B/hu not_active IP Right Cessation
- 1985-04-29 ZA ZA853161A patent/ZA853161B/xx unknown
- 1985-04-29 DK DK190885A patent/DK165693C/da not_active IP Right Cessation
- 1985-04-29 KR KR1019850002872A patent/KR870000925B1/ko not_active IP Right Cessation
- 1985-04-29 IL IL75038A patent/IL75038A/xx not_active IP Right Cessation
- 1985-04-29 YU YU723/85A patent/YU43977B/xx unknown
- 1985-04-29 ES ES542703A patent/ES8605511A1/es not_active Expired
- 1985-04-29 SU SU853884505A patent/SU1380614A3/ru active
- 1985-04-29 FI FI851683A patent/FI81096C/fi not_active IP Right Cessation
- 1985-04-29 AU AU41790/85A patent/AU554271B2/en not_active Ceased
- 1985-04-29 NO NO851695A patent/NO164097C/no unknown
- 1985-04-30 JP JP60093524A patent/JPS60239474A/ja active Granted
- 1985-10-21 ES ES548073A patent/ES8606336A1/es not_active Expired
-
1986
- 1986-04-02 SU SU864027210A patent/SU1400508A3/ru active
-
1987
- 1987-06-18 YU YU1145/87A patent/YU44632B/xx unknown
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