NO164024C - Analogifremgangsmaate for fremstilling av terapeutisk aktive enantiomerer av substituerte fenylazacykloalkaner. - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk aktive enantiomerer av substituerte fenylazacykloalkaner.Info
- Publication number
- NO164024C NO164024C NO831040A NO831040A NO164024C NO 164024 C NO164024 C NO 164024C NO 831040 A NO831040 A NO 831040A NO 831040 A NO831040 A NO 831040A NO 164024 C NO164024 C NO 164024C
- Authority
- NO
- Norway
- Prior art keywords
- group
- carbon atoms
- alkyl group
- hydrogen
- chem
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical compound C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- -1 2,6-dimethylphenyl Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 125000004208 3-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C([H])C(*)=C1[H] 0.000 abstract 1
- 125000004203 4-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Psychiatry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8202023A SE446335B (sv) | 1982-03-30 | 1982-03-30 | Ren enantiomer av en metasubstituerad 3-fenyl-1-propylpiperidin |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO831040L NO831040L (no) | 1983-10-03 |
| NO164024B NO164024B (no) | 1990-05-14 |
| NO164024C true NO164024C (no) | 1990-08-22 |
Family
ID=20346417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO831040A NO164024C (no) | 1982-03-30 | 1983-03-23 | Analogifremgangsmaate for fremstilling av terapeutisk aktive enantiomerer av substituerte fenylazacykloalkaner. |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0097628B1 (en16) |
| JP (1) | JPS58177971A (en16) |
| AT (1) | ATE56705T1 (en16) |
| AU (1) | AU564287B2 (en16) |
| CA (1) | CA1202307A (en16) |
| DD (1) | DD209621A5 (en16) |
| DE (1) | DE3381885D1 (en16) |
| DK (1) | DK162214C (en16) |
| ES (3) | ES521080A0 (en16) |
| FI (1) | FI81088C (en16) |
| GB (1) | GB2117771B (en16) |
| GR (1) | GR79244B (en16) |
| HU (1) | HU191290B (en16) |
| IE (1) | IE55261B1 (en16) |
| NO (1) | NO164024C (en16) |
| PT (1) | PT76481B (en16) |
| SE (1) | SE446335B (en16) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8305362D0 (sv) * | 1983-09-30 | 1983-09-30 | Astra Laekemedel Ab | Novel substituted phenylazacycloalkanes, processes for preparation and pharmaceutical preparations for such compounds |
| SE9904724D0 (sv) * | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| JP2011057619A (ja) * | 2009-09-10 | 2011-03-24 | Tokai Univ | 光学活性アミン化合物の製造方法、並びに、ジアステレオマー塩及びその製造方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU542153B2 (en) * | 1979-12-05 | 1985-02-07 | Per Arvid Emil Carlsson | New phenyl-azacycloalkanes |
-
1982
- 1982-03-30 SE SE8202023A patent/SE446335B/sv unknown
-
1983
- 1983-03-23 NO NO831040A patent/NO164024C/no unknown
- 1983-03-25 AU AU12845/83A patent/AU564287B2/en not_active Ceased
- 1983-03-28 IE IE685/83A patent/IE55261B1/en not_active IP Right Cessation
- 1983-03-28 EP EP83850084A patent/EP0097628B1/en not_active Expired - Lifetime
- 1983-03-28 AT AT83850084T patent/ATE56705T1/de not_active IP Right Cessation
- 1983-03-28 DE DE8383850084T patent/DE3381885D1/de not_active Expired - Fee Related
- 1983-03-29 GB GB08308657A patent/GB2117771B/en not_active Expired
- 1983-03-29 HU HU831073A patent/HU191290B/hu not_active IP Right Cessation
- 1983-03-29 CA CA000424804A patent/CA1202307A/en not_active Expired
- 1983-03-29 JP JP58051781A patent/JPS58177971A/ja active Granted
- 1983-03-29 GR GR70924A patent/GR79244B/el unknown
- 1983-03-29 FI FI831068A patent/FI81088C/fi not_active IP Right Cessation
- 1983-03-29 DK DK143483A patent/DK162214C/da not_active IP Right Cessation
- 1983-03-29 ES ES521080A patent/ES521080A0/es active Granted
- 1983-03-30 PT PT76481A patent/PT76481B/pt not_active IP Right Cessation
- 1983-03-30 DD DD83249351A patent/DD209621A5/de not_active IP Right Cessation
-
1984
- 1984-03-01 ES ES530186A patent/ES530186A0/es active Granted
- 1984-12-24 ES ES539031A patent/ES539031A0/es active Granted
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