NO161673C - Analogifremgangsm te for fremstilling av nye, substituerte 1,8-naftyridin-2-yl-amider. - Google Patents
Analogifremgangsm te for fremstilling av nye, substituerte 1,8-naftyridin-2-yl-amider.Info
- Publication number
- NO161673C NO161673C NO852877A NO852877A NO161673C NO 161673 C NO161673 C NO 161673C NO 852877 A NO852877 A NO 852877A NO 852877 A NO852877 A NO 852877A NO 161673 C NO161673 C NO 161673C
- Authority
- NO
- Norway
- Prior art keywords
- radical
- alkyloxy
- alkyl
- het
- optionally substituted
- Prior art date
Links
- 150000001408 amides Chemical class 0.000 title abstract 2
- -1 alkyloxy radical Chemical class 0.000 abstract 12
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 239000001961 anticonvulsive agent Substances 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- BQIKRTGTPBOIMK-UHFFFAOYSA-N [O]C[O] Chemical group [O]C[O] BQIKRTGTPBOIMK-UHFFFAOYSA-N 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000006404 alkylpyridazinyl group Chemical group 0.000 abstract 1
- 230000003556 anti-epileptic effect Effects 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 229960003965 antiepileptics Drugs 0.000 abstract 1
- 239000002249 anxiolytic agent Substances 0.000 abstract 1
- 230000000949 anxiolytic effect Effects 0.000 abstract 1
- 229940005530 anxiolytics Drugs 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Chemical group 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000003678 cyclohexadienyl group Chemical group C1(=CC=CCC1)* 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 239000003326 hypnotic agent Substances 0.000 abstract 1
- 230000000147 hypnotic effect Effects 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- KHUXNRRPPZOJPT-UHFFFAOYSA-N phenoxy radical Chemical compound O=C1C=C[CH]C=C1 KHUXNRRPPZOJPT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002098 pyridazinyl group Chemical group 0.000 abstract 1
- 125000005554 pyridyloxy group Chemical group 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 125000005942 tetrahydropyridyl group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cephalosporin Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8411442A FR2567887B1 (fr) | 1984-07-19 | 1984-07-19 | Nouveaux amides substitues, leur preparation et les medicaments qui les contiennent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO852877L NO852877L (no) | 1986-01-20 |
| NO161673B NO161673B (no) | 1989-06-05 |
| NO161673C true NO161673C (no) | 1989-09-13 |
Family
ID=9306273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO852877A NO161673C (no) | 1984-07-19 | 1985-07-18 | Analogifremgangsm te for fremstilling av nye, substituerte 1,8-naftyridin-2-yl-amider. |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US4642308A (pt) |
| EP (1) | EP0172083B1 (pt) |
| JP (1) | JPS6163656A (pt) |
| KR (1) | KR860001100A (pt) |
| AT (1) | ATE33652T1 (pt) |
| AU (1) | AU572672B2 (pt) |
| CA (1) | CA1224787A (pt) |
| CS (1) | CS253730B2 (pt) |
| DD (1) | DD240011A5 (pt) |
| DE (1) | DE3562250D1 (pt) |
| DK (1) | DK327285A (pt) |
| ES (1) | ES8604584A1 (pt) |
| FI (1) | FI79313C (pt) |
| FR (1) | FR2567887B1 (pt) |
| GR (1) | GR851774B (pt) |
| HU (1) | HU199802B (pt) |
| IL (1) | IL75817A (pt) |
| MA (1) | MA20487A1 (pt) |
| NO (1) | NO161673C (pt) |
| NZ (1) | NZ212764A (pt) |
| OA (1) | OA08069A (pt) |
| PH (1) | PH21301A (pt) |
| PL (1) | PL145331B1 (pt) |
| PT (1) | PT80840B (pt) |
| SU (1) | SU1417797A3 (pt) |
| YU (1) | YU118785A (pt) |
| ZA (1) | ZA855409B (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0208621B1 (fr) * | 1985-07-11 | 1989-04-12 | Rhone-Poulenc Sante | Amides substitués, leur préparation et compositions qui les contiennent |
| FR2592882B2 (fr) * | 1986-01-16 | 1988-03-11 | Rhone Poulenc Sante | Nouveaux amides substitues, leur preparation et les medicaments qui les contiennent |
| US4753941A (en) * | 1986-01-16 | 1988-06-28 | Rhone-Poulenc Sante | Amides based on certain 1,8-naphtyridine-2-amines useful as anxiolytics |
| US5197518A (en) * | 1991-06-27 | 1993-03-30 | Double Containment Systems | Centering support assembly for double containment pipe systems |
| GB9711257D0 (en) | 1997-05-30 | 1997-07-30 | Smithkline Beecham Plc | Novel compounds |
| US6340690B1 (en) * | 1999-02-22 | 2002-01-22 | Bio-Chem Pharma Inc. | Antiviral methods using [1,8]naphthyridine derivatives |
| US7432281B2 (en) | 2003-10-07 | 2008-10-07 | Renovis, Inc. | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same |
| US20080300243A1 (en) * | 2005-02-28 | 2008-12-04 | Kelly Michael G | Amide Derivatives as Ion-Channel Ligands and Pharmaceutical Compositions and Methods of Using the Same |
| US7576099B2 (en) | 2005-02-28 | 2009-08-18 | Renovis, Inc. | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same |
| WO2013090725A1 (en) * | 2011-12-15 | 2013-06-20 | Philadelphia Health & Education Corporation | NOVEL PI3K p110 INHIBITORS AND METHODS OF USE THEREOF |
| CN105646487B (zh) * | 2016-03-15 | 2017-12-05 | 红河学院 | 一类溴代1,8‑萘啶衍生物及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1006725A (fr) * | 1948-08-31 | 1952-04-28 | Cilag Spa | Nouveaux dérivés de la naphtyridine et procédé pour leur préparation |
| GB661515A (en) * | 1948-08-31 | 1951-11-21 | Cilag Ltd | Process for the production of naphthyridine derivatives |
| US3389142A (en) * | 1966-09-29 | 1968-06-18 | Bristol Myers Co | Esters of 2-substituted 1, 2-dihydroquinoline-nu-carboxylic acids and thione acids |
| US3576809A (en) * | 1968-05-06 | 1971-04-27 | Miles Lab | 2-substituted derivatives of 6-methoxyquinoline |
| US3624097A (en) * | 1969-07-22 | 1971-11-30 | Warner Lambert Co | N-pyridine 5-aminooxazoles |
| US4466965A (en) * | 1982-07-26 | 1984-08-21 | American Hospital Supply Corporation | Phthalazine compounds, compositions and use |
-
1984
- 1984-07-19 FR FR8411442A patent/FR2567887B1/fr not_active Expired
-
1985
- 1985-06-28 CA CA000485859A patent/CA1224787A/fr not_active Expired
- 1985-07-15 IL IL75817A patent/IL75817A/xx unknown
- 1985-07-16 MA MA20712A patent/MA20487A1/fr unknown
- 1985-07-17 PL PL1985254570A patent/PL145331B1/pl unknown
- 1985-07-17 GR GR851774A patent/GR851774B/el unknown
- 1985-07-17 ZA ZA855409A patent/ZA855409B/xx unknown
- 1985-07-17 DD DD85278694A patent/DD240011A5/de unknown
- 1985-07-17 NZ NZ212764A patent/NZ212764A/en unknown
- 1985-07-17 AU AU45090/85A patent/AU572672B2/en not_active Ceased
- 1985-07-17 US US06/755,896 patent/US4642308A/en not_active Expired - Fee Related
- 1985-07-18 FI FI852821A patent/FI79313C/fi not_active IP Right Cessation
- 1985-07-18 EP EP85401480A patent/EP0172083B1/fr not_active Expired
- 1985-07-18 DK DK327285A patent/DK327285A/da not_active Application Discontinuation
- 1985-07-18 SU SU853923698A patent/SU1417797A3/ru active
- 1985-07-18 CS CS855344A patent/CS253730B2/cs unknown
- 1985-07-18 KR KR1019850005134A patent/KR860001100A/ko not_active Withdrawn
- 1985-07-18 ES ES545336A patent/ES8604584A1/es not_active Expired
- 1985-07-18 HU HU852764A patent/HU199802B/hu not_active IP Right Cessation
- 1985-07-18 DE DE8585401480T patent/DE3562250D1/de not_active Expired
- 1985-07-18 NO NO852877A patent/NO161673C/no unknown
- 1985-07-18 AT AT85401480T patent/ATE33652T1/de not_active IP Right Cessation
- 1985-07-18 PH PH32541A patent/PH21301A/en unknown
- 1985-07-19 YU YU01187/85A patent/YU118785A/xx unknown
- 1985-07-19 OA OA58648A patent/OA08069A/xx unknown
- 1985-07-19 PT PT80840A patent/PT80840B/pt not_active IP Right Cessation
- 1985-07-19 JP JP60158504A patent/JPS6163656A/ja active Pending
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