NO160212C - Analogifremgangsmaate til fremstilling av nye karboksylsyreestere med anti-inflammatoriske virkninger. - Google Patents

Analogifremgangsmaate til fremstilling av nye karboksylsyreestere med anti-inflammatoriske virkninger.

Info

Publication number
NO160212C
NO160212C NO843298A NO843298A NO160212C NO 160212 C NO160212 C NO 160212C NO 843298 A NO843298 A NO 843298A NO 843298 A NO843298 A NO 843298A NO 160212 C NO160212 C NO 160212C
Authority
NO
Norway
Prior art keywords
preparation
carboxylic acid
acid esters
inflammatory effects
analogy procedure
Prior art date
Application number
NO843298A
Other languages
English (en)
Norwegian (no)
Other versions
NO843298L (no
NO160212B (no
Inventor
Julius Schmidlin
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO843298L publication Critical patent/NO843298L/no
Publication of NO160212B publication Critical patent/NO160212B/no
Publication of NO160212C publication Critical patent/NO160212C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Fats And Perfumes (AREA)
NO843298A 1983-08-18 1984-08-17 Analogifremgangsmaate til fremstilling av nye karboksylsyreestere med anti-inflammatoriske virkninger. NO160212C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH451283 1983-08-18

Publications (3)

Publication Number Publication Date
NO843298L NO843298L (no) 1985-02-19
NO160212B NO160212B (no) 1988-12-12
NO160212C true NO160212C (no) 1989-03-22

Family

ID=4277476

Family Applications (1)

Application Number Title Priority Date Filing Date
NO843298A NO160212C (no) 1983-08-18 1984-08-17 Analogifremgangsmaate til fremstilling av nye karboksylsyreestere med anti-inflammatoriske virkninger.

Country Status (21)

Country Link
US (1) US4607028A (da)
EP (1) EP0135476B1 (da)
JP (1) JPS6058999A (da)
KR (1) KR850001725A (da)
AT (1) ATE37186T1 (da)
AU (1) AU3204484A (da)
CA (1) CA1234564A (da)
CY (1) CY1593A (da)
DD (1) DD227966A5 (da)
DE (1) DE3474025D1 (da)
DK (1) DK160993C (da)
ES (1) ES8601234A1 (da)
FI (1) FI80888C (da)
GR (1) GR80131B (da)
HK (1) HK42791A (da)
HU (1) HUT34991A (da)
IL (1) IL72702A0 (da)
NO (1) NO160212C (da)
PT (1) PT79106B (da)
SG (1) SG32091G (da)
ZA (1) ZA846406B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78144A0 (en) * 1985-04-04 1986-07-31 Draco Ab Novel androstane-17beta-carboxylic acid esters
JPH04506066A (ja) * 1989-06-16 1992-10-22 ジ・アップジョン・カンパニー 脈管形成を抑制するためのスラミン・タイプの化合物および脈管形成抑止ステロイド類
FR2701262B1 (fr) * 1993-02-05 1995-03-24 Roussel Uclaf Nouveau procédé de préparation de stéroïdes 6 alpa, 9 alpha-difluorés et nouveaus intermédiaires.
JPH07119308A (ja) * 1993-10-27 1995-05-09 Koa:Kk 移動作業床による外壁貼りの吊り支え工法並にその装置
GB9501286D0 (en) * 1995-01-24 1995-03-15 Ciba Geigy Ag Pharmaceutical compositions and preparations thereof
US5981517A (en) * 1996-05-09 1999-11-09 Soft Drugs, Inc. Androstene derivatives
AUPP583198A0 (en) * 1998-09-11 1998-10-01 Soltec Research Pty Ltd Mousse composition
GB0015876D0 (en) * 2000-06-28 2000-08-23 Novartis Ag Organic compounds
US6777400B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
OA12394A (en) * 2000-08-05 2004-07-09 Glaxo Group Ltd 6.Alpha-,9.alpha.-difluoro-17.alpha.-'(2-furanylcarboxyl)oxyl-11.beta.-hydroxy-16.alpha.-methyl-3-oxo-androst-1,4,-diene-17-carbothioic acid s-fuoromethyl ester as an anti-inflammatory agent.
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858593B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6787532B2 (en) * 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
US6750210B2 (en) * 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
GB0029562D0 (en) * 2000-12-04 2001-01-17 Novartis Ag Organic compounds
UA77656C2 (en) * 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
EP2039700A2 (en) * 2001-04-30 2009-03-25 Glaxo Group Limited Novel anti-inflammatory androstane derivatives
GB0202216D0 (en) * 2002-01-31 2002-03-20 Glaxo Group Ltd Novel compounds
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) * 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1384372A (en) * 1971-01-20 1975-02-19 Glaxo Lab Ltd Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids
GB1514476A (en) * 1974-08-30 1978-06-14 Glaxo Lab Ltd Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates
JPS5297597A (en) * 1976-02-09 1977-08-16 Walt Disney Prod Guide device of ship
JPS5938239B2 (ja) * 1976-02-12 1984-09-14 グラクソ・ラボラトリ−ス・リミテツド 新規ステロイド化合物
CH628355A5 (de) * 1976-02-24 1982-02-26 Ciba Geigy Ag Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.
CH634081A5 (en) * 1977-04-13 1983-01-14 Ciba Geigy Ag Process for the preparation of novel androstadiene-17beta-carboxylic acid esters
ZA814440B (en) * 1980-07-10 1982-10-27 Otsuka Pharma Co Ltd Soft steroids having anti-inflammatory activity

Also Published As

Publication number Publication date
FI80888C (fi) 1990-08-10
AU3204484A (en) 1985-02-21
ES535242A0 (es) 1985-11-01
EP0135476B1 (de) 1988-09-14
ATE37186T1 (de) 1988-09-15
DK160993B (da) 1991-05-13
DD227966A5 (de) 1985-10-02
HUT34991A (en) 1985-05-28
JPH0253440B2 (da) 1990-11-16
SG32091G (en) 1991-06-21
DE3474025D1 (en) 1988-10-20
CY1593A (en) 1992-04-03
DK396284A (da) 1985-02-19
FI843219A (fi) 1985-02-19
JPS6058999A (ja) 1985-04-05
PT79106B (en) 1986-11-14
ZA846406B (en) 1985-03-27
CA1234564A (en) 1988-03-29
NO843298L (no) 1985-02-19
DK396284D0 (da) 1984-08-17
FI843219A0 (fi) 1984-08-15
ES8601234A1 (es) 1985-11-01
EP0135476A2 (de) 1985-03-27
EP0135476A3 (en) 1985-12-18
DK160993C (da) 1991-11-04
GR80131B (en) 1984-12-19
PT79106A (en) 1984-09-01
FI80888B (fi) 1990-04-30
HK42791A (en) 1991-06-07
IL72702A0 (en) 1984-11-30
KR850001725A (ko) 1985-04-01
US4607028A (en) 1986-08-19
NO160212B (no) 1988-12-12

Similar Documents

Publication Publication Date Title
NO160212C (no) Analogifremgangsmaate til fremstilling av nye karboksylsyreestere med anti-inflammatoriske virkninger.
JPS5278848A (en) Preparation of novel propionic acid ester derivatives
NO158508C (no) Analogifremgangsmaate for fremstilling av antiinflammatorisk virksomme 4-pregnenderivater.
GB1490603A (en) Glycerides with anti-inflammatory properties
JPS523046A (en) Prepration of 4-homotwistane-3-carboxylic acid esters
JPS5265263A (en) Azetidinone compounds
JPS5227715A (en) Process for preparation of gamma-halogeno-delta- unsaturated carboxylic acid ester and/or gamma-lactone derivatives
JPS51131821A (en) Process for preparation of gamma-halo-delta-unsaturated carboxylic acids
JPS51131857A (en) Process for preparation of substituted cyclopropanecarboxylic acid est ers
JPS52153965A (en) Triazolylacetic acid derivatives
JPS51131818A (en) Process for preparation of r-unsaturated carboxylic acid esters
JPS52118441A (en) 2-carbamoyl-3-methyl-3-(4-isobutylphenyl)glycidic acid derivatives an d method of preparing the same
JPS527935A (en) Preparation of substituted phenylacetic acid derivatives
JPS5210271A (en) A process for preparing 2-substituted thiazole-4-carboxylic acid amide derivatives
JPS5283714A (en) Novel alkyl ester derivatives of 16-alkyl-20-alkoxyprostadienoic acids
JPS5242858A (en) Synthetic method of triphenyl phosphite
JPS5273880A (en) Synthesis of dihydrocarbostyril derivatives
JPS51115481A (en) Process for preparation of (3,4-dihydro-6-carbostyril)carboxylic and e ster derivatives
JPS51133246A (en) Process for preparing 3- benzyloxyphenylacetic acids
JPS5242854A (en) Process for preparation of 2-oxyethylcyclopenta necarboxylic acid derivatives
JPS51128961A (en) Process for preparing 8-azaprostanoic acid derivatives
JPS5253838A (en) Preparation of novel 16-alkyl-20-alkoxyprostadienoic acid alkyl ester derivtives