NO157136B - Analogifremgangsmaate for fremstilling av terapeutisk aktive homocykliske derivater. - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk aktive homocykliske derivater. Download PDFInfo
- Publication number
- NO157136B NO157136B NO832574A NO832574A NO157136B NO 157136 B NO157136 B NO 157136B NO 832574 A NO832574 A NO 832574A NO 832574 A NO832574 A NO 832574A NO 157136 B NO157136 B NO 157136B
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- Norway
- Prior art keywords
- stands
- radical
- group
- slide
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- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- 150000003254 radicals Chemical class 0.000 abstract 5
- -1 hydroxyalkyl radical Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- CFHIDWOYWUOIHU-UHFFFAOYSA-N oxomethyl Chemical compound O=[CH] CFHIDWOYWUOIHU-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000006073 displacement reaction Methods 0.000 description 2
- 239000002243 precursor Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/86—Ring systems containing bridged rings containing four rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Description
Apparat for kopiering og gravering, spesielt for anbringelse på tverrsleden i pinoldreiebenker.
Den foreliggende oppfinnelse angår et
apparat for kopiering og gravering, spesielt for anbringelse på tverrsleden i pinoldreiebenker, med en dobbeltpanograf som samvirker med en fast sjablon, mens det annet leddparallellogram er forbundet med verktøyet.
Hensikten med oppfinnelsen er å til-veiebringe et særlig effektivt apparat av denne art, ved hjelp av hvilket man kan tilvirke arbeidsstykker med hvilkensom-helst omkretsform, spesielt underskjærin-ger eller serieartikler.
Apparatet ifølge oppfinnelsen karak-teriseres ved at det første leddparallellogram har et fastpunkt på en plate, på hvilken en første sleide styres, og tjener til styring av en tversgående annen sleide, som er leddet forbundet med dels det før-ste leddparallellogram og dels med det annet leddparallellogram, hvis langside som bærer føleren, er parallell med den annen sleide.
Andre trekk ved apparatet vil bli for-klart i det følgende under henvisning til tegningen, som viser apparatet sett oven-fra med de nærliggende deler av en pinol-dreiebenk antydet ved strekpunkterte lin-jer.
Apparatet omfatter en sleide 1, som er
U-formet og løper på dreiebenkens tverr-slede 2. Sleiden 1 styres på en frontplate 3, som er leddet forbundet med det ene ledd-punkt 4 i et leddparallellogram 5, som er
anordnet over frontplaten 3 og forløper
skrått i forhold til denne. Den er forlenget og er med enden av forlengelsen 7 leddet forbundet med en leddstang 9 som bærer føl-eren 10 og som danner den ene langside i et annet leddparallellogram 11,
beliggende under det første leddparallellogram 5 og forløpende tilnærmelsesvis pa-rallelt med dreiebenkens lengdeakse.
Det annet leddparallellogram 11 er med endene av sine to langsider 9, 9' leddet forbundet med henholdsvis de ene vinkel-armer hvis ene armer 14, 15 således danner kortsidene i leddparallellogrammet 11, mens deres andre armer 18, 19 med sine ytterender er leddet forbundet ved 20, 21 med en annen sleide 22, som i sin ene ende bærer en verktøyholder 23. Denne verk-tøy-bærende sleide 22 løper langs den
førstnevnte sleide 1 i dennes lengderetning.
Den førstnevnte sleide 1 løper på sin side vinkelrett på den verktøy-bærende sleide 22 og beveger seg sammen med denne når
apparatet settes i bevegelse ved hjelp av
føleren 10 over de forbundne leddparallello-grammer 5, 11.
Ved hjelp av apparatet ifølge oppfinnelsen kan det fremstilles f. eks. maskindeler med en hvilken som helst omkretsform, og spesielt underskj æringer eller serieartikler.
Den verktøy-bærende sleide 22 er for-synt med et fremskytende anlegg 24 med et roterbart hode 25, som er innrettet til å styre samt fastholde i enhver ønsket stil-ling den ene langside 26 i det første leddparallellogram 5.
Størrelsesforholdet mellom modellen 27 og arbeidsstykket 28 kan varieres ved regulerbar forskyvning av kortsidene 29, 6 i forhold til langsidene 26, 30, og ved regulerbar forskyvning av langsidene i forhold til anlegget 24.
Apparatet har i praksis vist seg å være meget nøyaktig og effektivt og muliggjør fremstilling av maskindeler som i form svarer til modellen 27 (sjablon, mal).
Claims (4)
1. Apparat for kopiering og gravering, spesielt for anbringelse på tverr-sleden i pinoldreiebenker, med en dobbeltpanto-graf, av hvilken det ene leddparallellogram bærer føleren, som samvirker med en fast sjablon, mens det annet leddparallellogram er forbundet med verktøyet, karakterisert ved at det første leddparallellogram (5) har et fastpunkt (4) på en plate (3), på hvilken en første sleide (1) styres, og tjener til styring av en tverrsgående annen sleide (22), som er leddet forbundet med dels det første parallellogram (5) og dels med det annet leddparallellogram (11) hvis langside (9), som bærer føleren (10), er parallell med den annen sleide (22).
2. Apparat ifølge påstand 1, karakterisert ved at den første sleide (1) har U-form, på hvis tverrdel den annen sleide (22) styres.
3. Apparat ifølge påstand 1 eller 2, karakterisert ved at leddpunktet (25) mellom den annen sleide (22) og det før-ste leddparallellogram (5) kan forskyves og fastholdes langs en parallellogramside (26).
4. Apparat ifølge en av de foregående påstander, karakterisert ved at det annet parallellograms (11) kortsider (14, 15) er vinkelformet.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8232084 | 1982-11-10 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO832574L NO832574L (no) | 1984-05-11 |
| NO157136B true NO157136B (no) | 1987-10-19 |
| NO157136C NO157136C (no) | 1988-01-27 |
Family
ID=10534162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO832574A NO157136C (no) | 1982-11-10 | 1983-07-15 | Analogifremgangsmaate for fremstilling av terapeutisk aktive homocykliske derivater. |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US4803201A (no) |
| EP (1) | EP0112603B2 (no) |
| JP (1) | JPS5988438A (no) |
| AT (1) | ATE25661T1 (no) |
| AU (1) | AU572787B2 (no) |
| CA (1) | CA1243025A (no) |
| DE (1) | DE3369965D1 (no) |
| DK (1) | DK332283A (no) |
| ES (2) | ES8604105A1 (no) |
| FI (1) | FI80440C (no) |
| GR (1) | GR78865B (no) |
| HU (1) | HU196159B (no) |
| IE (1) | IE55772B1 (no) |
| IL (1) | IL69319A (no) |
| NO (1) | NO157136C (no) |
| NZ (1) | NZ204933A (no) |
| PT (1) | PT77086B (no) |
| ZA (1) | ZA835252B (no) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5387520A (en) * | 1992-08-27 | 1995-02-07 | Worcester Foundation For Experimental Biology | Treatment of tumor cells in vitro with neurotrophic factors and cell proliferation inhibitors |
| US7396534B2 (en) * | 2004-05-11 | 2008-07-08 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Cosmetic compositions containing Nigrospora sphaerica extracts |
| CN108165496B (zh) * | 2017-12-01 | 2020-09-08 | 国家海洋局第三海洋研究所 | 富克尔核盘菌3a00494及其发酵化合物在制备抗肿瘤药物中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1331520A (en) * | 1971-01-27 | 1973-09-26 | Ici Ltd | Aphidicolin and derivatives thereof |
| US3761512A (en) * | 1972-02-28 | 1973-09-25 | Ici Ltd | Anti-viral compounds |
| FR2500440A1 (fr) * | 1981-02-23 | 1982-08-27 | Roussel Uclaf | Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one disubstituee en position 6, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one disubstituee en position 6, et leur procede de preparation ainsi que des produits intermediaires |
| JPS62155232A (ja) * | 1985-12-27 | 1987-07-10 | Rikagaku Kenkyusho | アフイデイコリン誘導体及びその合成法並びに制癌剤 |
-
1983
- 1983-07-15 AT AT83304118T patent/ATE25661T1/de not_active IP Right Cessation
- 1983-07-15 NO NO832574A patent/NO157136C/no unknown
- 1983-07-15 DE DE8383304118T patent/DE3369965D1/de not_active Expired
- 1983-07-15 EP EP83304118A patent/EP0112603B2/en not_active Expired - Lifetime
- 1983-07-18 IE IE1676/83A patent/IE55772B1/en not_active IP Right Cessation
- 1983-07-18 NZ NZ204933A patent/NZ204933A/en unknown
- 1983-07-19 ZA ZA835252A patent/ZA835252B/xx unknown
- 1983-07-19 FI FI832622A patent/FI80440C/fi not_active IP Right Cessation
- 1983-07-19 DK DK332283A patent/DK332283A/da not_active Application Discontinuation
- 1983-07-20 HU HU832560A patent/HU196159B/hu not_active IP Right Cessation
- 1983-07-20 CA CA000432812A patent/CA1243025A/en not_active Expired
- 1983-07-22 PT PT77086A patent/PT77086B/pt not_active IP Right Cessation
- 1983-07-22 AU AU17201/83A patent/AU572787B2/en not_active Ceased
- 1983-07-25 IL IL69319A patent/IL69319A/xx not_active IP Right Cessation
- 1983-08-05 JP JP58142641A patent/JPS5988438A/ja active Granted
- 1983-08-31 GR GR72119A patent/GR78865B/el unknown
- 1983-09-01 ES ES525299A patent/ES8604105A1/es not_active Expired
-
1984
- 1984-04-26 ES ES531941A patent/ES531941A0/es active Granted
-
1987
- 1987-05-28 US US07/054,897 patent/US4803201A/en not_active Expired - Lifetime
-
1990
- 1990-09-17 US US07/584,490 patent/US5039710A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0112603A1 (en) | 1984-07-04 |
| ZA835252B (en) | 1984-06-27 |
| EP0112603B2 (en) | 1992-03-18 |
| ES8604105A1 (es) | 1986-01-16 |
| GR78865B (no) | 1984-10-02 |
| JPH0480890B2 (no) | 1992-12-21 |
| JPS5988438A (ja) | 1984-05-22 |
| NO832574L (no) | 1984-05-11 |
| PT77086B (en) | 1986-01-24 |
| ES525299A0 (es) | 1986-01-16 |
| IE831676L (en) | 1984-05-10 |
| NO157136C (no) | 1988-01-27 |
| HU196159B (en) | 1988-10-28 |
| DK332283A (da) | 1984-05-11 |
| ES8506756A1 (es) | 1985-08-01 |
| FI80440C (fi) | 1990-06-11 |
| US5039710A (en) | 1991-08-13 |
| PT77086A (en) | 1983-08-01 |
| DE3369965D1 (en) | 1987-04-09 |
| AU1720183A (en) | 1984-05-17 |
| FI832622A0 (fi) | 1983-07-19 |
| ATE25661T1 (de) | 1987-03-15 |
| CA1243025A (en) | 1988-10-11 |
| EP0112603B1 (en) | 1987-03-04 |
| FI80440B (fi) | 1990-02-28 |
| NZ204933A (en) | 1986-12-05 |
| ES531941A0 (es) | 1985-08-01 |
| DK332283D0 (da) | 1983-07-19 |
| IL69319A (en) | 1987-01-30 |
| AU572787B2 (en) | 1988-05-19 |
| IE55772B1 (en) | 1991-01-16 |
| US4803201A (en) | 1989-02-07 |
| FI832622A (fi) | 1984-05-11 |
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