GB1331520A - Aphidicolin and derivatives thereof - Google Patents

Aphidicolin and derivatives thereof

Info

Publication number
GB1331520A
GB1331520A GB1331520DA GB1331520A GB 1331520 A GB1331520 A GB 1331520A GB 1331520D A GB1331520D A GB 1331520DA GB 1331520 A GB1331520 A GB 1331520A
Authority
GB
United Kingdom
Prior art keywords
aphidicolin
derivatives
compound
hemisuccinate
monoacetate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of GB1331520A publication Critical patent/GB1331520A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/18—Saturated compounds containing keto groups
    • C07C62/24—Saturated compounds containing keto groups the keto group being part of a ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/507—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
    • C07C49/513—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1331520 Aphidicolin and its derivatives IMPERIAL CHEMICAL INDUSTRIES Ltd 9 Feb 1972 [27 Jan 1971 20 Oct 1971] 3280/71 and 48719/71 Heading C2C [Also in Division A5] The novel compound of the Formula I or its mirror image (with the trivial name Aphidicolin) its 9α-monoacetate, its 9α-hemisuccinate and pharmaceutical-acceptable salts thereof may be prepared by cultivating a compound I producing strain of Cephalosporium aphidicola in a suitable nutrient medium and isolating the product therefrom optionally followed by ester and/or salt formation.
GB1331520D 1971-01-27 1971-01-27 Aphidicolin and derivatives thereof Expired GB1331520A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB328071 1971-01-27

Publications (1)

Publication Number Publication Date
GB1331520A true GB1331520A (en) 1973-09-26

Family

ID=9755362

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1331520D Expired GB1331520A (en) 1971-01-27 1971-01-27 Aphidicolin and derivatives thereof

Country Status (1)

Country Link
GB (1) GB1331520A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112603A1 (en) * 1982-11-10 1984-07-04 Imperial Chemical Industries Plc Aphidicolane derivatives, their preparation and pharmaceutical compositions comprising them
US5008252A (en) * 1987-03-20 1991-04-16 The University Of North Carolina At Chapel Hill Process for inhibiting herpes simplex virus-specified thymidine kinase

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112603A1 (en) * 1982-11-10 1984-07-04 Imperial Chemical Industries Plc Aphidicolane derivatives, their preparation and pharmaceutical compositions comprising them
US4803201A (en) * 1982-11-10 1989-02-07 Imperial Chemical Industries Plc Homocyclic derivatives
US5039710A (en) * 1982-11-10 1991-08-13 Imperial Chemical Industries Plc Homocyclic derivatives
US5008252A (en) * 1987-03-20 1991-04-16 The University Of North Carolina At Chapel Hill Process for inhibiting herpes simplex virus-specified thymidine kinase

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees