NO148377C - 3-CHLORO-7-ALFA-AMINO-ACYLCEPHALOSPORINE COMPOUNDS FOR USE AS INTERMEDIATES IN THE PREPARATION OF THERAPEUTICALLY EFFECTIVE CEPHALOSPORINE DERIVATIVES - Google Patents

3-CHLORO-7-ALFA-AMINO-ACYLCEPHALOSPORINE COMPOUNDS FOR USE AS INTERMEDIATES IN THE PREPARATION OF THERAPEUTICALLY EFFECTIVE CEPHALOSPORINE DERIVATIVES

Info

Publication number
NO148377C
NO148377C NO792681A NO792681A NO148377C NO 148377 C NO148377 C NO 148377C NO 792681 A NO792681 A NO 792681A NO 792681 A NO792681 A NO 792681A NO 148377 C NO148377 C NO 148377C
Authority
NO
Norway
Prior art keywords
acylcephalosporine
alfa
intermediates
chloro
amino
Prior art date
Application number
NO792681A
Other languages
Norwegian (no)
Other versions
NO148377B (en
NO792681L (en
Inventor
Robert Raymond Chauvette
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO792681L publication Critical patent/NO792681L/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO148377B publication Critical patent/NO148377B/en
Publication of NO148377C publication Critical patent/NO148377C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
NO792681A 1973-02-23 1979-08-16 3-CHLORO-7-ALFA-AMINO-ACYLCEPHALOSPORINE COMPOUNDS FOR USE AS INTERMEDIATES IN THE PREPARATION OF THERAPEUTICALLY EFFECTIVE CEPHALOSPORINE DERIVATIVES NO148377C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33538173A 1973-02-23 1973-02-23

Publications (3)

Publication Number Publication Date
NO792681L NO792681L (en) 1974-08-26
NO148377B NO148377B (en) 1983-06-20
NO148377C true NO148377C (en) 1983-09-28

Family

ID=23311540

Family Applications (2)

Application Number Title Priority Date Filing Date
NO740606A NO148375C (en) 1973-02-23 1974-02-22 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 3-CHLORO-7-ALFA-AMINO-ACYLCEPHALOSPORINE
NO792681A NO148377C (en) 1973-02-23 1979-08-16 3-CHLORO-7-ALFA-AMINO-ACYLCEPHALOSPORINE COMPOUNDS FOR USE AS INTERMEDIATES IN THE PREPARATION OF THERAPEUTICALLY EFFECTIVE CEPHALOSPORINE DERIVATIVES

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO740606A NO148375C (en) 1973-02-23 1974-02-22 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 3-CHLORO-7-ALFA-AMINO-ACYLCEPHALOSPORINE

Country Status (37)

Country Link
JP (4) JPS6139313B2 (en)
AR (1) AR199510A1 (en)
AT (1) AT333953B (en)
BE (1) BE811495A (en)
BR (1) BR7401384D0 (en)
CA (1) CA1016537A (en)
CH (1) CH593988A5 (en)
CS (1) CS187409B2 (en)
CY (1) CY1043A (en)
DD (1) DD110278A5 (en)
DE (1) DE2408698C2 (en)
DK (1) DK153157C (en)
EG (1) EG11104A (en)
ES (1) ES423531A1 (en)
FI (1) FI63035C (en)
FR (1) FR2218877B1 (en)
GB (1) GB1461323A (en)
GT (1) GT197432133A (en)
HK (1) HK20080A (en)
HU (1) HU166849B (en)
IE (1) IE39046B1 (en)
IL (1) IL44262A (en)
IN (1) IN139620B (en)
KE (1) KE3027A (en)
MW (1) MW674A1 (en)
MY (1) MY8100024A (en)
NL (1) NL179057C (en)
NO (2) NO148375C (en)
OA (1) OA04809A (en)
PH (1) PH9616A (en)
PL (1) PL88702B1 (en)
RO (1) RO64663A (en)
SE (1) SE411212B (en)
SU (1) SU676166A3 (en)
YU (1) YU36970B (en)
ZA (1) ZA741191B (en)
ZM (1) ZM3574A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT342197B (en) * 1975-02-20 1978-03-28 Ciba Geigy Ag NEW PROCESS FOR PRODUCING 3-CEPHEM CONNECTIONS
CH619233A5 (en) * 1975-07-31 1980-09-15 Ciba Geigy Ag
CH622802A5 (en) * 1975-08-20 1981-04-30 Ciba Geigy Ag
IE45158B1 (en) * 1976-08-16 1982-06-30 Lilly Co Eli 3-chloro-cephem synthesis
DE3508258A1 (en) * 1985-03-08 1986-09-18 Bayer Ag, 5090 Leverkusen SS LACTAMANTIBIOTICS, METHOD FOR THE PRODUCTION AND THEIR USE AS AND IN MEDICINAL PRODUCTS
DE3509618A1 (en) 1985-03-16 1986-09-18 Bayer Ag, 5090 Leverkusen SS LACTAM ANTIBIOTICS, METHOD FOR THE PRODUCTION AND THEIR USE AS A MEDICINAL PRODUCT
JPS6436445U (en) * 1987-08-28 1989-03-06
DE3803169A1 (en) 1988-02-03 1989-08-17 Bayer Ag SS LACTAM ANTIBIOTICS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS AND IN MEDICINAL PRODUCTS
ES2010075A6 (en) * 1989-01-10 1989-10-16 Antibioticos Sa Process for the preparation of 3-chloro-cefem compounds.
JP2539459Y2 (en) * 1991-12-18 1997-06-25 三重ホーロー株式会社 Assembled garbage incinerator
IT1255458B (en) * 1992-05-11 1995-11-02 Col Marco Da PROCEDURE FOR THE PREPARATION OF HALOGENATED BETA-LACTAMIC DERIVATIVES
ES2079327B1 (en) 1994-12-13 1996-08-01 Lilly Sa PHARMACEUTICAL FORMULATIONS OF CEFACLOR.
CN101805357B (en) * 2010-04-28 2012-01-11 陶灵刚 Cefaclor compound and novel preparation method thereof
CN103588790A (en) * 2013-11-29 2014-02-19 中国科学院长春应用化学研究所 Preparation method of 7-amino-3-chloro-3-cephem-4-carboxylic acid-p-nitrobenzyl ester
CN106632400A (en) * 2016-12-16 2017-05-10 石家庄柏奇化工有限公司 Method for preparing 7-ACCA by removing 4-nitrobenzyl through catalytic hydrogenation of Pd-C

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
DE2265798C2 (en) * 1971-06-24 1985-09-26 Fujisawa Pharmaceutical Co., Ltd., Osaka Process for the preparation of oxoazetidine derivatives
AR206201A1 (en) * 1972-06-29 1976-07-07 Ciba Geigy Ag PROCEDURE FOR OBTAINING ACID COMPOUNDS 7BETA-AMINO-3-CEFEM-3-01-4-CARBOXILICO0-SUBSTITUIDOS

Also Published As

Publication number Publication date
IL44262A0 (en) 1974-05-16
EG11104A (en) 1976-12-31
IL44262A (en) 1977-08-31
IE39046B1 (en) 1978-07-19
DK153157C (en) 1988-10-31
JPS6139313B2 (en) 1986-09-03
GB1461323A (en) 1977-01-13
BE811495A (en) 1974-08-22
NL179057C (en) 1986-07-01
IN139620B (en) 1976-07-10
DE2408698C2 (en) 1983-11-10
JPS6140237B2 (en) 1986-09-08
FI63035C (en) 1983-04-11
NO148375B (en) 1983-06-20
PL88702B1 (en) 1976-09-30
ATA142574A (en) 1976-04-15
KE3027A (en) 1980-03-14
AU6591674A (en) 1975-08-28
JPS6140236B2 (en) 1986-09-08
HU166849B (en) 1975-06-28
DD110278A5 (en) 1974-12-12
AR199510A1 (en) 1974-09-09
JPS6140235B2 (en) 1986-09-08
PH9616A (en) 1976-01-20
CY1043A (en) 1980-08-01
SU676166A3 (en) 1979-07-25
IE39046L (en) 1974-08-23
YU36970B (en) 1984-08-31
GT197432133A (en) 1975-08-16
DE2408698A1 (en) 1974-09-05
BR7401384D0 (en) 1974-11-05
FR2218877A1 (en) 1974-09-20
MY8100024A (en) 1981-12-31
JPS49110689A (en) 1974-10-22
AT333953B (en) 1976-12-27
NO148377B (en) 1983-06-20
SE411212B (en) 1979-12-10
JPS56138190A (en) 1981-10-28
ZM3574A1 (en) 1975-11-21
NL179057B (en) 1986-02-03
JPS56138192A (en) 1981-10-28
CS187409B2 (en) 1979-01-31
CH593988A5 (en) 1977-12-30
MW674A1 (en) 1975-04-09
OA04809A (en) 1980-08-31
ZA741191B (en) 1975-10-29
NO740606L (en) 1974-08-26
RO64663A (en) 1979-02-15
ES423531A1 (en) 1976-05-16
HK20080A (en) 1980-04-25
CA1016537A (en) 1977-08-30
JPS56138191A (en) 1981-10-28
FR2218877B1 (en) 1977-03-11
NL7402489A (en) 1974-08-27
FI63035B (en) 1982-12-31
NO792681L (en) 1974-08-26
YU39974A (en) 1982-06-18
NO148375C (en) 1983-09-28
DK153157B (en) 1988-06-20

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