RO64663A - Process for the preparation of 3-halogen-cephalosporin compounds - Google Patents

Process for the preparation of 3-halogen-cephalosporin compounds

Info

Publication number
RO64663A
RO64663A RO7477796A RO7779674A RO64663A RO 64663 A RO64663 A RO 64663A RO 7477796 A RO7477796 A RO 7477796A RO 7779674 A RO7779674 A RO 7779674A RO 64663 A RO64663 A RO 64663A
Authority
RO
Romania
Prior art keywords
halogen
preparation
process
cephalosporin compounds
cephalosporin
Prior art date
Application number
RO7477796A
Other languages
French (fr)
Inventor
Robert Chauvette
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US33538173A priority Critical
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of RO64663A publication Critical patent/RO64663A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of products other than chlorine, adipic acid, caprolactam, or chlorodifluoromethane, e.g. bulk or fine chemicals or pharmaceuticals
    • Y02P20/55Synthetic design, e.g. reducing the use of auxiliary or protecting groups
RO7477796A 1973-02-23 1974-02-23 Process for the preparation of 3-halogen-cephalosporin compounds RO64663A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US33538173A true 1973-02-23 1973-02-23

Publications (1)

Publication Number Publication Date
RO64663A true RO64663A (en) 1979-02-15

Family

ID=23311540

Family Applications (1)

Application Number Title Priority Date Filing Date
RO7477796A RO64663A (en) 1973-02-23 1974-02-23 Process for the preparation of 3-halogen-cephalosporin compounds

Country Status (37)

Country Link
JP (4) JPS6139313B2 (en)
AR (1) AR199510A1 (en)
AT (1) AT333953B (en)
BE (1) BE811495A (en)
BR (1) BR7401384D0 (en)
CA (1) CA1016537A (en)
CH (1) CH593988A5 (en)
CS (1) CS187409B2 (en)
CY (1) CY1043A (en)
DD (1) DD110278A5 (en)
DE (1) DE2408698C2 (en)
DK (1) DK153157C (en)
EG (1) EG11104A (en)
ES (1) ES423531A1 (en)
FI (1) FI63035C (en)
FR (1) FR2218877B1 (en)
GB (1) GB1461323A (en)
GT (1) GT197432133A (en)
HK (1) HK20080A (en)
HU (1) HU166849B (en)
IE (1) IE39046B1 (en)
IL (1) IL44262A (en)
IN (1) IN139620B (en)
KE (1) KE3027A (en)
MW (1) MW674A1 (en)
MY (1) MY8100024A (en)
NL (1) NL179057C (en)
NO (2) NO148375C (en)
OA (1) OA4809A (en)
PH (1) PH9616A (en)
PL (1) PL88702B1 (en)
RO (1) RO64663A (en)
SE (1) SE411212B (en)
SU (1) SU676166A3 (en)
YU (1) YU36970B (en)
ZA (1) ZA7401191B (en)
ZM (1) ZM3574A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT342197B (en) * 1975-02-20 1978-03-28 Ciba Geigy Ag cephem-3 new process for the production of
CH619233A5 (en) * 1975-07-31 1980-09-15 Ciba Geigy Ag
CH622802A5 (en) * 1975-08-20 1981-04-30 Ciba Geigy Ag
IE45158B1 (en) * 1976-08-16 1982-06-30 Lilly Co Eli 3-chloro-cephem synthesis
DE3508258A1 (en) * 1985-03-08 1986-09-18 Bayer Ag Ss-lactam antibiotics, process for manufacture and their use as pharmaceuticals and
DE3509618A1 (en) * 1985-03-16 1986-09-18 Bayer Ag Ss-lactam antibiotics, process for manufacture and their use as medicines
JPS6436445U (en) * 1987-08-28 1989-03-06
DE3803169A1 (en) 1988-02-03 1989-08-17 Bayer Ag Ss-lactam antibiotics, process for their production and their use as pharmaceuticals and
ES2010075A6 (en) * 1989-01-10 1989-10-16 Antibioticos Sa A process for the preparation of compounds of 3-chloro-cephem.
JP2539459Y2 (en) * 1991-12-18 1997-06-25 三重ホーロー株式会社 Prefabricated garbage incinerator
IT1255458B (en) * 1992-05-11 1995-11-02 Col Marco Da Process for the preparation of beta-lactam halogenated
ES2079327B1 (en) 1994-12-13 1996-08-01 Lilly Sa Pharmaceutical formulations of cefaclor.
CN101805357B (en) * 2010-04-28 2012-01-11 陶灵刚 Cefaclor compound and novel preparation method thereof
CN103588790A (en) * 2013-11-29 2014-02-19 中国科学院长春应用化学研究所 Preparation method of 7-amino-3-chloro-3-cephem-4-carboxylic acid-p-nitrobenzyl ester
CN106632400A (en) * 2016-12-16 2017-05-10 石家庄柏奇化工有限公司 Method for preparing 7-ACCA by removing 4-nitrobenzyl through catalytic hydrogenation of Pd-C

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
FR2143211B1 (en) * 1971-06-24 1975-10-31 Fujisawa Pharmaceutical Co
AR206201A1 (en) * 1972-06-29 1976-07-07 Ciba Geigy Ag Procedure for obtaining acid compounds 7beta-amino-3-cephem-3-01-4-carboxilico0-substituted

Also Published As

Publication number Publication date
AR199510A1 (en) 1974-09-09
DK153157B (en) 1988-06-20
DE2408698A1 (en) 1974-09-05
OA4809A (en) 1980-08-31
CA1016537A1 (en)
JPS56138191A (en) 1981-10-28
AU6591674A (en) 1975-08-28
JPS56138192A (en) 1981-10-28
IN139620B (en) 1976-07-10
GT197432133A (en) 1975-08-16
JPS6140235B2 (en) 1986-09-08
ZM3574A1 (en) 1975-11-21
EG11104A (en) 1976-12-31
CA1016537A (en) 1977-08-30
NL179057B (en) 1986-02-03
ES423531A1 (en) 1976-05-16
BE811495A (en) 1974-08-22
FI63035C (en) 1983-04-11
PL88702B1 (en) 1976-09-30
DE2408698C2 (en) 1983-11-10
BR7401384D0 (en) 1974-11-05
PH9616A (en) 1976-01-20
SE411212B (en) 1979-12-10
IE39046B1 (en) 1978-07-19
HK20080A (en) 1980-04-25
IL44262A (en) 1977-08-31
CS187409B2 (en) 1979-01-31
CH593988A5 (en) 1977-12-30
NO148377C (en) 1983-09-28
JPS49110689A (en) 1974-10-22
DD110278A5 (en) 1974-12-12
SU676166A3 (en) 1979-07-25
FR2218877A1 (en) 1974-09-20
FR2218877B1 (en) 1977-03-11
NL179057C (en) 1986-07-01
DK153157C (en) 1988-10-31
JPS6140236B2 (en) 1986-09-08
HU166849B (en) 1975-06-28
MY8100024A (en) 1981-12-31
JPS56138190A (en) 1981-10-28
ZA7401191B (en) 1975-10-29
CY1043A (en) 1980-08-01
GB1461323A (en) 1977-01-13
NL7402489A (en) 1974-08-27
IE39046L (en) 1974-08-23
ATA142574A (en) 1976-04-15
JPS6140237B2 (en) 1986-09-08
YU36970B (en) 1984-08-31
AT333953B (en) 1976-12-27
KE3027A (en) 1980-03-14
MW674A1 (en) 1975-04-09
NO148375B (en) 1983-06-20
YU39974A (en) 1982-06-18
NO148377B (en) 1983-06-20
FI63035B (en) 1982-12-31
NO792681L (en) 1974-08-26
IL44262D0 (en) 1974-05-16
JPS6139313B2 (en) 1986-09-03
BE811495A1 (en)
NO148375C (en) 1983-09-28

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