NO135901B - - Google Patents
Download PDFInfo
- Publication number
- NO135901B NO135901B NO2655/72A NO265572A NO135901B NO 135901 B NO135901 B NO 135901B NO 2655/72 A NO2655/72 A NO 2655/72A NO 265572 A NO265572 A NO 265572A NO 135901 B NO135901 B NO 135901B
- Authority
- NO
- Norway
- Prior art keywords
- chloro
- trifluoroethyl
- ether
- difluoromethyl ether
- mixture
- Prior art date
Links
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 claims description 69
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 65
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 claims description 44
- 239000000203 mixture Substances 0.000 claims description 36
- PIWKPBJCKXDKJR-UHFFFAOYSA-N Isoflurane Chemical compound FC(F)OC(Cl)C(F)(F)F PIWKPBJCKXDKJR-UHFFFAOYSA-N 0.000 claims description 31
- 229960002725 isoflurane Drugs 0.000 claims description 31
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 claims description 24
- 238000009835 boiling Methods 0.000 claims description 17
- 238000000034 method Methods 0.000 claims description 11
- TZZWXBLENLGFDD-UHFFFAOYSA-N 2-chloro-2-[chloro(difluoro)methoxy]-1,1,1-trifluoroethane Chemical compound FC(F)(F)C(Cl)OC(F)(F)Cl TZZWXBLENLGFDD-UHFFFAOYSA-N 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 238000004821 distillation Methods 0.000 claims description 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 13
- 150000002170 ethers Chemical class 0.000 description 6
- 239000006227 byproduct Substances 0.000 description 5
- 230000015572 biosynthetic process Effects 0.000 description 4
- 238000000926 separation method Methods 0.000 description 4
- 125000001028 difluoromethyl group Chemical group [H]C(F)(F)* 0.000 description 3
- 238000004508 fractional distillation Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 238000000746 purification Methods 0.000 description 3
- 230000003444 anaesthetic effect Effects 0.000 description 2
- 238000004587 chromatography analysis Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 238000004817 gas chromatography Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000011541 reaction mixture Substances 0.000 description 2
- ZASBKNPRLPFSCA-UHFFFAOYSA-N 2-(difluoromethoxy)-1,1,1-trifluoroethane Chemical compound FC(F)OCC(F)(F)F ZASBKNPRLPFSCA-UHFFFAOYSA-N 0.000 description 1
- XOBKSJJDNFUZPF-UHFFFAOYSA-N Methoxyethane Chemical class CCOC XOBKSJJDNFUZPF-UHFFFAOYSA-N 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000004811 liquid chromatography Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000003822 preparative gas chromatography Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/34—Separation; Purification; Stabilisation; Use of additives
- C07C41/40—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation
- C07C41/42—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation by distillation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16839971A | 1971-08-02 | 1971-08-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
NO135901B true NO135901B (fr) | 1977-03-14 |
NO135901C NO135901C (fr) | 1977-06-22 |
Family
ID=22611343
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO2655/72A NO135901C (fr) | 1971-08-02 | 1972-07-25 |
Country Status (19)
Country | Link |
---|---|
US (1) | US3720587A (fr) |
JP (1) | JPS528808B2 (fr) |
AR (1) | AR192960A1 (fr) |
AU (1) | AU442153B2 (fr) |
BE (1) | BE786675A (fr) |
BR (1) | BR7204982D0 (fr) |
CA (1) | CA976500A (fr) |
CH (1) | CH549543A (fr) |
DE (1) | DE2234309A1 (fr) |
DK (1) | DK141164B (fr) |
ES (1) | ES405150A1 (fr) |
FR (1) | FR2148036B1 (fr) |
GB (1) | GB1352484A (fr) |
IL (1) | IL39835A (fr) |
IT (1) | IT1048259B (fr) |
NL (1) | NL146141B (fr) |
NO (1) | NO135901C (fr) |
SE (1) | SE392887B (fr) |
ZA (1) | ZA724947B (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2610538B2 (ja) * | 1990-04-13 | 1997-05-14 | 日本メクトロン株式会社 | パーフルオロ(プロピルビニルエーテル)の精製法 |
US5230778A (en) * | 1992-05-01 | 1993-07-27 | Gavlin Associates | Purification of isoflurane by extractive distillation |
DK1765294T3 (da) * | 2004-05-12 | 2008-11-10 | Baxter Int | Nukleinsyremikrokugler samt deres fremstilling og afgivelse |
US7605291B2 (en) * | 2006-04-27 | 2009-10-20 | Adalberto Maldonado | Method for the preparation of volatile Anesthetics |
WO2008036858A2 (fr) * | 2006-09-20 | 2008-03-27 | The Board Of Regents Of The University Of Texas System | procédé pour administrer des anesthésiants volatils pour une anesthésie locale et/ou le soulagement de la douleur |
EP3581169A1 (fr) | 2008-01-22 | 2019-12-18 | The Board Of Regents Of The University Of Texas System | Compositions anesthésiques volatiles comprenant des solvants d'extraction pour une anesthésie régionale et/ou un soulagement de la douleur |
WO2013005178A1 (fr) * | 2011-07-05 | 2013-01-10 | Piramal Healthcare Limited | Procédé continu pour la purification de l'éther 1-chloro-2,2,2-trifluoroéthyl-difluorométhylique (isoflurane) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2442589A (en) * | 1946-03-19 | 1948-06-01 | Atomic Energy Commission | Purification of perfluoroheptane by azeotropic distillation with methyl ethyl ketone |
NL131714C (fr) * | 1963-02-06 | |||
US3406099A (en) * | 1965-09-16 | 1968-10-15 | Allied Chem | Distillation of an azeotropic mixture of cf3cocf3 hf and ccl2fccif2 |
US3501533A (en) * | 1967-09-06 | 1970-03-17 | Allied Chem | Recovery of fluorinated ether |
US3535388A (en) * | 1969-05-12 | 1970-10-20 | Air Reduction | 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether |
-
0
- BE BE786675D patent/BE786675A/fr not_active IP Right Cessation
-
1971
- 1971-08-02 US US00168399A patent/US3720587A/en not_active Expired - Lifetime
-
1972
- 1972-05-18 DE DE2234309A patent/DE2234309A1/de active Granted
- 1972-07-05 AU AU44236/72A patent/AU442153B2/en not_active Expired
- 1972-07-05 IL IL39835A patent/IL39835A/xx unknown
- 1972-07-07 GB GB3201072A patent/GB1352484A/en not_active Expired
- 1972-07-07 SE SE7209054A patent/SE392887B/xx unknown
- 1972-07-13 CA CA147,082A patent/CA976500A/en not_active Expired
- 1972-07-18 ZA ZA724947A patent/ZA724947B/xx unknown
- 1972-07-21 NL NL727210156A patent/NL146141B/xx not_active IP Right Cessation
- 1972-07-21 IT IT51679/72A patent/IT1048259B/it active Protection Beyond IP Right Term
- 1972-07-25 CH CH1107572A patent/CH549543A/fr not_active IP Right Cessation
- 1972-07-25 DK DK367972AA patent/DK141164B/da not_active IP Right Cessation
- 1972-07-25 NO NO2655/72A patent/NO135901C/no unknown
- 1972-07-26 JP JP47074929A patent/JPS528808B2/ja not_active Expired
- 1972-07-26 ES ES405150A patent/ES405150A1/es not_active Expired
- 1972-07-26 FR FR727226910A patent/FR2148036B1/fr not_active Expired
- 1972-07-26 AR AR243274A patent/AR192960A1/es active
- 1972-07-26 BR BR4982/72A patent/BR7204982D0/pt unknown
Also Published As
Publication number | Publication date |
---|---|
ZA724947B (en) | 1973-04-25 |
BE786675A (fr) | 1973-01-25 |
NO135901C (fr) | 1977-06-22 |
CA976500A (en) | 1975-10-21 |
DE2234309B2 (fr) | 1974-04-11 |
DE2234309C3 (fr) | 1974-11-14 |
FR2148036A1 (fr) | 1973-03-11 |
DK141164C (fr) | 1980-07-28 |
SE392887B (sv) | 1977-04-25 |
NL7210156A (fr) | 1973-02-06 |
US3720587A (en) | 1973-03-13 |
IL39835A (en) | 1974-12-31 |
DE2234309A1 (de) | 1973-02-15 |
BR7204982D0 (pt) | 1973-05-15 |
IL39835A0 (en) | 1972-09-28 |
GB1352484A (en) | 1974-05-08 |
ES405150A1 (es) | 1976-02-16 |
JPS4828408A (fr) | 1973-04-14 |
AR192960A1 (es) | 1973-03-21 |
DK141164B (da) | 1980-01-28 |
FR2148036B1 (fr) | 1974-07-26 |
AU442153B2 (en) | 1973-11-15 |
JPS528808B2 (fr) | 1977-03-11 |
AU4423672A (en) | 1973-11-15 |
NL146141B (nl) | 1975-06-16 |
CH549543A (fr) | 1974-05-31 |
IT1048259B (it) | 1980-11-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6179967B1 (en) | Purification process of pentrafluoroethane | |
KR20100021488A (ko) | 이온성 액체를 사용하여 플루오로카본을 분리하는 방법 | |
NO327774B1 (no) | Fremgangsmate for fremstilling av maursyre | |
Summerbell et al. | The Stereochemistry of the 2, 3-Dichloro-p-dioxanes | |
NO135901B (fr) | ||
US3846332A (en) | Azeotropes of 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether with acetone, methyl ethylketone and tetrahydrofuran | |
US4897161A (en) | Separation of vinyl acetate from ethyl acetate by extractive distillation | |
US2779720A (en) | Condenser | |
US20230150902A1 (en) | Method for producing purified trans-1,2-difluoroethylene (hfo-1132(e)) and/or 1,1,2-trifluoroethylene (hfo-1123) | |
US4925533A (en) | Separation of vinyl acetate from ethyl acetate by extractive distillation with acids or acid amides | |
US5154800A (en) | Dehydration of acrylic acid by extractive distillation | |
US5358608A (en) | Separation of 1-propanol from 2-butanol by extractive distillation | |
US5439561A (en) | Separation of 3-methyl-2-butanol from 2-pentanol by azeotropic | |
US4710275A (en) | Separation of isopropanol from t-butanol by extractive distillation | |
NO146772B (no) | Fremgangsmaate for utvinning av dimetylkarbonat fra en azeotrop blanding med metanol | |
US4670106A (en) | Separation of n-amyl acetate and water from n-amyl alcohol by extractive distillation | |
US3409512A (en) | Azeotropic distillation of fluorinated ether and acetonitrile | |
US5092966A (en) | Separation of methylene chloride from ethyl ether by extractive distillation | |
US4601791A (en) | Separation of n-propanol from allyl alcohol by extractive distillation | |
US5407541A (en) | Separation of 3-methyl-2-butanol from 2-pentanol by azeotropic distillation | |
US4695350A (en) | Separation of n-hexyl acetate from n-hexyl alcohol by extractive distillation | |
US3917723A (en) | Process for the continuous manufacture of m-chloronitrobenzene from m-dinitrobenzene | |
CN111433178A (zh) | (z)-1-氯-2,3,3,3-四氟丙烯的纯化方法 | |
EP3950651A1 (fr) | Composition azéotropique ou de type azéotropique comprenant du fluorure d'hydrogène et du 1,1,2-trichloroéthane, du trans-1,2-dichloroéthylène ou du cis-1,2-dichloroéthylène | |
US4859285A (en) | Separation of 2-pentanone from formic acid by extractive distillation |