NO127154B - - Google Patents
Download PDFInfo
- Publication number
- NO127154B NO127154B NO16734067A NO16734067A NO127154B NO 127154 B NO127154 B NO 127154B NO 16734067 A NO16734067 A NO 16734067A NO 16734067 A NO16734067 A NO 16734067A NO 127154 B NO127154 B NO 127154B
- Authority
- NO
- Norway
- Prior art keywords
- acid
- methyl
- thiazole
- stated
- aliphatic
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 claims description 18
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 16
- 239000002253 acid Substances 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 5
- 125000001931 aliphatic group Chemical group 0.000 claims description 4
- 125000004432 carbon atom Chemical group C* 0.000 claims description 4
- SUMDYPCJJOFFON-UHFFFAOYSA-N isethionic acid Chemical compound OCCS(O)(=O)=O SUMDYPCJJOFFON-UHFFFAOYSA-N 0.000 claims description 4
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 claims description 4
- 150000007513 acids Chemical class 0.000 claims description 2
- CCIVGXIOQKPBKL-UHFFFAOYSA-N ethanesulfonic acid Chemical compound CCS(O)(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-N 0.000 claims description 2
- 229940045996 isethionic acid Drugs 0.000 claims description 2
- 239000003960 organic solvent Substances 0.000 claims description 2
- AFAXGSQYZLGZPG-UHFFFAOYSA-N ethanedisulfonic acid Chemical compound OS(=O)(=O)CCS(O)(=O)=O AFAXGSQYZLGZPG-UHFFFAOYSA-N 0.000 claims 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 21
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 10
- 239000000243 solution Substances 0.000 description 8
- 238000002425 crystallisation Methods 0.000 description 4
- 230000008025 crystallization Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 206010002091 Anaesthesia Diseases 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- -1 aliphatic alcohols Chemical class 0.000 description 2
- 230000037005 anaesthesia Effects 0.000 description 2
- MIOPJNTWMNEORI-UHFFFAOYSA-N camphorsulfonic acid Chemical compound C1CC2(CS(O)(=O)=O)C(=O)CC1C2(C)C MIOPJNTWMNEORI-UHFFFAOYSA-N 0.000 description 2
- HPXRVTGHNJAIIH-UHFFFAOYSA-N cyclohexanol Chemical compound OC1CCCCC1 HPXRVTGHNJAIIH-UHFFFAOYSA-N 0.000 description 2
- AFAXGSQYZLGZPG-UHFFFAOYSA-L ethane-1,2-disulfonate Chemical compound [O-]S(=O)(=O)CCS([O-])(=O)=O AFAXGSQYZLGZPG-UHFFFAOYSA-L 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000155 melt Substances 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- 238000001953 recrystallisation Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 150000003557 thiazoles Chemical class 0.000 description 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical class [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 1
- 206010012225 Delirium tremens Diseases 0.000 description 1
- 241001539473 Euphoria Species 0.000 description 1
- 206010015535 Euphoric mood Diseases 0.000 description 1
- 206010026749 Mania Diseases 0.000 description 1
- 244000223014 Syzygium aromaticum Species 0.000 description 1
- 235000016639 Syzygium aromaticum Nutrition 0.000 description 1
- FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical compound C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000001773 anti-convulsant effect Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 210000003710 cerebral cortex Anatomy 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 150000001805 chlorine compounds Chemical class 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 230000002920 convulsive effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 210000000695 crystalline len Anatomy 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- DSGUSEBCDAKBCM-UHFFFAOYSA-N ethane-1,2-disulfonic acid;dihydrate Chemical compound O.O.OS(=O)(=O)CCS(O)(=O)=O DSGUSEBCDAKBCM-UHFFFAOYSA-N 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- OPUAWDUYWRUIIL-UHFFFAOYSA-L methanedisulfonate Chemical compound [O-]S(=O)(=O)CS([O-])(=O)=O OPUAWDUYWRUIIL-UHFFFAOYSA-L 0.000 description 1
- LLKWEEDJFSNIAI-UHFFFAOYSA-N methanedisulfonic acid;dihydrate Chemical compound O.O.OS(=O)(=O)CS(O)(=O)=O LLKWEEDJFSNIAI-UHFFFAOYSA-N 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 201000000980 schizophrenia Diseases 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 150000003460 sulfonic acids Chemical class 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Landscapes
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO16734067A NO127154B (xx) | 1967-03-17 | 1967-03-17 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO16734067A NO127154B (xx) | 1967-03-17 | 1967-03-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO127154B true NO127154B (xx) | 1973-05-14 |
Family
ID=19909989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO16734067A NO127154B (xx) | 1967-03-17 | 1967-03-17 |
Country Status (1)
| Country | Link |
|---|---|
| NO (1) | NO127154B (xx) |
-
1967
- 1967-03-17 NO NO16734067A patent/NO127154B/no unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4792025B2 (ja) | ５−ヒドロキシインドール−３−カルボン酸エステル類誘導体およびその用途 | |
| BRPI0807319B1 (pt) | Base de minociclina cristalina forma 1, processo para preparar base de minociclina cristalina forma i, base de minociclina cristalina forma ii, processo para preparar base de minociclina cristalina forma ii, base de minociclina cristalina forma iii e processo para preparar base de minociclina cristalina forma iii | |
| BR112015029463B1 (pt) | Bissulfato de inibidor da janus quinase (jak), seu uso e seu método de preparação, e composição farmacêutica | |
| PT80453B (pt) | Processo de preparacao de sais estaveis da sulfo-adenosil-l-metionina (same) especialmente adequados para medicamento oral | |
| CN102924443B (zh) | 含有杂环的5-羟基吲哚类衍生物及其用途 | |
| EP0000353A2 (de) | Bicyclische Thiadiazaverbindungen, Verfahren und Zwischenprodukte bei deren Herstellung, und Arzneimittel welche diese Verbindungen oder Zwischenprodukte enthalten | |
| NO127154B (xx) | ||
| EP2698371B1 (en) | Novel addition salt of an inhibitor of platelet aggregation | |
| US9487477B2 (en) | Crystalline phase of (3S,3S′) 4,4′-disulfanediylbis(3-aminobutane 1-sulfonic acid) with L-lysine | |
| CN112047931B (zh) | FXIa凝血因子抑制剂、其药物组合物和用途 | |
| PT98215B (pt) | Processo para a preparacao de citrato de 2-hidroxi-1,2,3-propanotricarboxilato de 3-{(5-metil-2-furanil)metil}-n-(4-piperidinil)-3h-imidazo-{4,5-b}piridin-2-amina e de composicoes farmaceuticas que o contem | |
| CN116710102A (zh) | 一种五环三萜类化合物结晶及其制备方法 | |
| US3031457A (en) | Salts of 4-methyl-5 (beta-halogenoethyl)-thiazole and certain sulfonic acids | |
| US2720481A (en) | Bisulfite addition products of aldehyde derivatives of cortisone and hydrocortisone | |
| Manske | Lobinaline, an alkaloid from Lobelia cardinalis L. | |
| US2837513A (en) | Penicillin salts | |
| CN112047990B (zh) | 阿糖胞苷前药mb07133晶型及其应用 | |
| BR112019003949B1 (pt) | Sal de (r)-(1-metilpirrolidina-3-il)metil(3-cloro-4- fluoro-[1,1-bifenil] -2-il)carbamato inovador e uma forma cristalina dos mesmos | |
| PT86933B (pt) | Processo para a preparacao de derivados opticamente activos de oxo-isoindolinilo e de composicoes farmaceuticas que os contem | |
| BR112019010919B1 (pt) | Processo para preparar índigo carmim | |
| US1435187A (en) | hzsox | |
| US2477816A (en) | Benzil-acid derivative and process for the manufacture thereof | |
| Heidelberger et al. | SYNTHESES IN THE CINCHONA SERIES. X. DIHYDROCINCHONICINOL AND THE DIHYDROQUINICINOLS1 | |
| SE196140C1 (xx) | ||
| US1414333A (en) | Process for the preparation of the di-alkyl-amino-ethyl derivatives of theobromine |