NO126624B - - Google Patents

Download PDF

Info

Publication number
NO126624B
NO126624B NO01455/70A NO145570A NO126624B NO 126624 B NO126624 B NO 126624B NO 01455/70 A NO01455/70 A NO 01455/70A NO 145570 A NO145570 A NO 145570A NO 126624 B NO126624 B NO 126624B
Authority
NO
Norway
Prior art keywords
nitro
imidazolyl
methyl
carbon atoms
benzimidazole
Prior art date
Application number
NO01455/70A
Other languages
English (en)
Norwegian (no)
Inventor
Clemens Rufer
Eberhard Schroeder
Hans-Joachim Kessler
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO126624B publication Critical patent/NO126624B/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/95—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by nitrogen atoms, attached to other ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
    • C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
    • C07C209/325—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups reduction by other means than indicated in C07C209/34 or C07C209/36
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
    • C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
    • C07C209/36—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups by reduction of nitro groups bound to carbon atoms of six-membered aromatic rings in presence of hydrogen-containing gases and a catalyst
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO01455/70A 1969-04-19 1970-04-17 NO126624B (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1920635A DE1920635C3 (de) 1969-04-19 1969-04-19 2-(l-MethyI-5-nitro-2-imidazolyl)benzimidazole

Publications (1)

Publication Number Publication Date
NO126624B true NO126624B (fr) 1973-03-05

Family

ID=5732064

Family Applications (1)

Application Number Title Priority Date Filing Date
NO01455/70A NO126624B (fr) 1969-04-19 1970-04-17

Country Status (15)

Country Link
JP (1) JPS4914231B1 (fr)
AT (1) AT294075B (fr)
BE (1) BE749102A (fr)
CH (2) CH546774A (fr)
CS (1) CS167896B2 (fr)
DE (1) DE1920635C3 (fr)
DK (1) DK137758B (fr)
ES (1) ES378368A1 (fr)
FI (1) FI52861C (fr)
FR (1) FR2042351B1 (fr)
GB (1) GB1312056A (fr)
NL (1) NL7005703A (fr)
NO (1) NO126624B (fr)
SE (1) SE364962B (fr)
ZA (1) ZA702577B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053472A (en) * 1969-04-19 1977-10-11 Schering Aktiengesellschaft 2-(5-nitro-2-imidazolyl)-benzimidazoles
IT1043840B (it) * 1971-05-08 1980-02-29 Poli Ind Chimica Spa Pirimidine 2 5 disostituite e processo per la loro preparazione
US3996238A (en) * 1972-02-08 1976-12-07 Ciba-Geigy Corporation 4- or 5-Nitroimidazoles and processes for their manufacture
BE795636A (fr) * 1972-02-19 1973-08-20 Schering Ag Nitroimidazolylpyrimidines, et leur procede de preparation
PT78358B (en) * 1983-04-07 1986-05-30 Smith Kline French Lab Chemical process
EP0711768B1 (fr) * 1994-05-31 2002-02-13 Mitsui Chemicals, Inc. Derive de benzimidazol
WO1996006831A1 (fr) * 1994-08-26 1996-03-07 Auckland Division Cancer Society Of New Zealand Inc. Nouveaux agents d'alkilation cibles sur l'adn

Also Published As

Publication number Publication date
DK137758B (da) 1978-05-01
CS167896B2 (fr) 1976-05-28
JPS4914231B1 (fr) 1974-04-05
CH546768A (de) 1974-03-15
NL7005703A (fr) 1970-10-21
GB1312056A (en) 1973-04-04
ES378368A1 (es) 1972-06-16
DE1920635B2 (de) 1978-11-02
DE1920635A1 (de) 1970-10-29
FI52861C (fi) 1977-12-12
FR2042351B1 (fr) 1973-07-13
ZA702577B (en) 1971-01-27
AT294075B (de) 1971-11-10
DE1920635C3 (de) 1979-06-28
FR2042351A1 (fr) 1971-02-12
BE749102A (fr) 1970-10-19
DK137758C (fr) 1978-10-09
SE364962B (fr) 1974-03-11
CH546774A (de) 1974-03-15
FI52861B (fr) 1977-08-31

Similar Documents

Publication Publication Date Title
US5190942A (en) Benzoxazole and related heterocyclic substituted imidazole and benzimidazole derivatives
AU2008304439B2 (en) (s)-ethyl 2-amino-3-(4-(2-amino-6-((r)-1-(4-chloro-2-(3-methyl-1h-pyrazol-1-yl)phenyl)-2,2,2-trifluorethoxy)pyrimidin-4-yl)phenyl)propanoate
CN103059003B (zh) 具有抗真菌活性的苯并咪唑-1,2,3-三氮唑类化合物及其制备方法
CZ2005679A3 (cs) Zpusob odstranování trifenylmethanové chránící skupiny u prekursoru antihypertensních léciv
CA2627477A1 (fr) Nouveaux agonistes beta, leur procede de fabrication et leur utilisation en tant que medicaments
KR0183028B1 (ko) 벤즈이미다졸 유도체, 그 제조방법 및 의약물로서의 사용방법
AU2011342039B2 (en) Continuous arycyclic compound
CN106317025B (zh) 一种含三氟甲基吡唑的三唑类化合物及其制备方法和其应用
NO126624B (fr)
EP0510036B1 (fr) 4,5-diphenyl-imidazoles substitues en position 2
KR20100046026A (ko) 4-페닐-6-(2,2,2-트리플루오로-1-페닐에톡시)피리미딘-기재화합물의 제조 방법
JP6149104B2 (ja) トリアゾール化合物の調製方法
US3147270A (en) Substituted 2-imidazolines
US4436913A (en) 1H- and 2H- indazole derivatives
US20230150975A1 (en) Compounds used as kinase inhibitors and application thereof
NO742345L (fr)
US6156907A (en) Process for preparing 1-substituted 4-cyano-1,2,3-triazoles
JPS5826885A (ja) ６−｛５−〔ω−（１−イミダゾリル）−アルキル〕−チエン−２−イル｝−３−オキソ−２，３，４，５−テトラビドロ−ピリタジン化合物
CH505097A (de) Verfahren zur Herstellung heteroaromatischer Sulfone
SU1033003A3 (ru) Способ получени производных 4-пиримидона или их фармацевтически приемлемых кислотно-аддитивных солей
CN113999211B (zh) 一类特异性抗前列腺癌活性的含1,2,3-三氮唑的吲唑骨架衍生物
DK154295B (da) Analogifremgangsmaade til fremstilling af 2-nitroimidazol-derivater
JPS6025428B2 (ja) ４‐（ヒドロキシメチル）イミダゾール化合物の製法
US4053472A (en) 2-(5-nitro-2-imidazolyl)-benzimidazoles
US3378552A (en) Imidazole compounds and methods of making the same