NO120701B - - Google Patents
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- Publication number
- NO120701B NO120701B NO170373A NO17037367A NO120701B NO 120701 B NO120701 B NO 120701B NO 170373 A NO170373 A NO 170373A NO 17037367 A NO17037367 A NO 17037367A NO 120701 B NO120701 B NO 120701B
- Authority
- NO
- Norway
- Prior art keywords
- medium
- griseofulvin
- strain
- sulfur
- original
- Prior art date
Links
- 239000002609 medium Substances 0.000 claims description 50
- IIUZTXTZRGLYTI-UHFFFAOYSA-N Dihydrogriseofulvin Natural products COC1CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 IIUZTXTZRGLYTI-UHFFFAOYSA-N 0.000 claims description 32
- UXWOXTQWVMFRSE-UHFFFAOYSA-N Griseoviridin Natural products O=C1OC(C)CC=C(C(NCC=CC=CC(O)CC(O)C2)=O)SCC1NC(=O)C1=COC2=N1 UXWOXTQWVMFRSE-UHFFFAOYSA-N 0.000 claims description 32
- DDUHZTYCFQRHIY-UHFFFAOYSA-N Negwer: 6874 Natural products COC1=CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 DDUHZTYCFQRHIY-UHFFFAOYSA-N 0.000 claims description 32
- 229960002867 griseofulvin Drugs 0.000 claims description 32
- DDUHZTYCFQRHIY-RBHXEPJQSA-N griseofulvin Chemical compound COC1=CC(=O)C[C@@H](C)[C@@]11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 DDUHZTYCFQRHIY-RBHXEPJQSA-N 0.000 claims description 32
- 238000000034 method Methods 0.000 claims description 29
- 230000035772 mutation Effects 0.000 claims description 24
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 21
- 239000011593 sulfur Substances 0.000 claims description 19
- 229910052717 sulfur Inorganic materials 0.000 claims description 19
- 241000228143 Penicillium Species 0.000 claims description 9
- 230000002285 radioactive effect Effects 0.000 claims description 9
- 235000015097 nutrients Nutrition 0.000 claims description 8
- 239000001963 growth medium Substances 0.000 claims description 6
- 241000228127 Penicillium griseofulvum Species 0.000 claims description 5
- 150000003467 sulfuric acid derivatives Chemical class 0.000 claims description 2
- 229910021653 sulphate ion Inorganic materials 0.000 claims description 2
- 230000028070 sporulation Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 description 10
- 239000000725 suspension Substances 0.000 description 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
- 229920001817 Agar Polymers 0.000 description 7
- 239000008272 agar Substances 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 6
- 238000012216 screening Methods 0.000 description 6
- DKPFZGUDAPQIHT-UHFFFAOYSA-N Butyl acetate Natural products CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 description 5
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 description 5
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 description 5
- 239000012499 inoculation medium Substances 0.000 description 5
- 239000008101 lactose Substances 0.000 description 5
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 4
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 238000005266 casting Methods 0.000 description 4
- 235000013339 cereals Nutrition 0.000 description 4
- 239000000460 chlorine Substances 0.000 description 4
- 231100000350 mutagenesis Toxicity 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 229910052801 chlorine Inorganic materials 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 238000011081 inoculation Methods 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- PAWQVTBBRAZDMG-UHFFFAOYSA-N 2-(3-bromo-2-fluorophenyl)acetic acid Chemical compound OC(=O)CC1=CC=CC(Br)=C1F PAWQVTBBRAZDMG-UHFFFAOYSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 239000005864 Sulphur Substances 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical compound ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- -1 nitro- Chemical class 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000005258 radioactive decay Effects 0.000 description 2
- 230000001850 reproductive effect Effects 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000004804 winding Methods 0.000 description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 244000174111 Brassica adpressa Species 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 235000019738 Limestone Nutrition 0.000 description 1
- 102000011931 Nucleoproteins Human genes 0.000 description 1
- 108010061100 Nucleoproteins Proteins 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241001149507 Penicillium urticae Species 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 235000011941 Tilia x europaea Nutrition 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000009088 enzymatic function Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 239000004571 lime Substances 0.000 description 1
- 239000006028 limestone Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000877 morphologic effect Effects 0.000 description 1
- 239000003471 mutagenic agent Substances 0.000 description 1
- 239000006916 nutrient agar Substances 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000000941 radioactive substance Substances 0.000 description 1
- 239000001054 red pigment Substances 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 125000004434 sulfur atom Chemical group 0.000 description 1
- 229940065278 sulfur compound Drugs 0.000 description 1
- 150000003464 sulfur compounds Chemical class 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000002211 ultraviolet spectrum Methods 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 108700026220 vif Genes Proteins 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- E—FIXED CONSTRUCTIONS
- E04—BUILDING
- E04F—FINISHING WORK ON BUILDINGS, e.g. STAIRS, FLOORS
- E04F13/00—Coverings or linings, e.g. for walls or ceilings
- E04F13/07—Coverings or linings, e.g. for walls or ceilings composed of covering or lining elements; Sub-structures therefor; Fastening means therefor
- E04F13/08—Coverings or linings, e.g. for walls or ceilings composed of covering or lining elements; Sub-structures therefor; Fastening means therefor composed of a plurality of similar covering or lining elements
- E04F13/18—Coverings or linings, e.g. for walls or ceilings composed of covering or lining elements; Sub-structures therefor; Fastening means therefor composed of a plurality of similar covering or lining elements of organic plastics with or without reinforcements or filling materials or with an outer layer of organic plastics with or without reinforcements or filling materials; plastic tiles
-
- E—FIXED CONSTRUCTIONS
- E04—BUILDING
- E04F—FINISHING WORK ON BUILDINGS, e.g. STAIRS, FLOORS
- E04F13/00—Coverings or linings, e.g. for walls or ceilings
- E04F13/07—Coverings or linings, e.g. for walls or ceilings composed of covering or lining elements; Sub-structures therefor; Fastening means therefor
- E04F13/08—Coverings or linings, e.g. for walls or ceilings composed of covering or lining elements; Sub-structures therefor; Fastening means therefor composed of a plurality of similar covering or lining elements
- E04F13/0801—Separate fastening elements
- E04F13/0832—Separate fastening elements without load-supporting elongated furring elements between wall and covering elements
- E04F13/0833—Separate fastening elements without load-supporting elongated furring elements between wall and covering elements not adjustable
- E04F13/0835—Separate fastening elements without load-supporting elongated furring elements between wall and covering elements not adjustable the fastening elements extending into the back side of the covering elements
-
- E—FIXED CONSTRUCTIONS
- E04—BUILDING
- E04F—FINISHING WORK ON BUILDINGS, e.g. STAIRS, FLOORS
- E04F13/00—Coverings or linings, e.g. for walls or ceilings
- E04F13/07—Coverings or linings, e.g. for walls or ceilings composed of covering or lining elements; Sub-structures therefor; Fastening means therefor
- E04F13/08—Coverings or linings, e.g. for walls or ceilings composed of covering or lining elements; Sub-structures therefor; Fastening means therefor composed of a plurality of similar covering or lining elements
- E04F13/0875—Coverings or linings, e.g. for walls or ceilings composed of covering or lining elements; Sub-structures therefor; Fastening means therefor composed of a plurality of similar covering or lining elements having a basic insulating layer and at least one covering layer
- E04F13/0876—Coverings or linings, e.g. for walls or ceilings composed of covering or lining elements; Sub-structures therefor; Fastening means therefor composed of a plurality of similar covering or lining elements having a basic insulating layer and at least one covering layer the covering layer comprising mutual alignment or interlocking means
-
- E—FIXED CONSTRUCTIONS
- E04—BUILDING
- E04F—FINISHING WORK ON BUILDINGS, e.g. STAIRS, FLOORS
- E04F13/00—Coverings or linings, e.g. for walls or ceilings
- E04F13/07—Coverings or linings, e.g. for walls or ceilings composed of covering or lining elements; Sub-structures therefor; Fastening means therefor
- E04F13/08—Coverings or linings, e.g. for walls or ceilings composed of covering or lining elements; Sub-structures therefor; Fastening means therefor composed of a plurality of similar covering or lining elements
- E04F13/0885—Coverings or linings, e.g. for walls or ceilings composed of covering or lining elements; Sub-structures therefor; Fastening means therefor composed of a plurality of similar covering or lining elements specially adapted for being adhesively fixed to the wall; Fastening means therefor; Fixing by means of plastics materials hardening after application
Landscapes
- Engineering & Computer Science (AREA)
- Architecture (AREA)
- Civil Engineering (AREA)
- Structural Engineering (AREA)
- Building Environments (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEK60626A DE1296325B (de) | 1966-11-03 | 1966-11-03 | Gebaeude-Aussenwandverkleidung aus Waermedaemm-Bauplatten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO120701B true NO120701B (da) | 1970-11-23 |
Family
ID=7229677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO170373A NO120701B (da) | 1966-11-03 | 1967-11-02 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3435573A (da) |
| AT (1) | AT285126B (da) |
| BE (1) | BE705874A (da) |
| CH (1) | CH457796A (da) |
| DE (1) | DE1296325B (da) |
| DK (1) | DK124622B (da) |
| FI (1) | FI43232B (da) |
| GB (1) | GB1209773A (da) |
| NL (1) | NL6714769A (da) |
| NO (1) | NO120701B (da) |
| SE (1) | SE321066B (da) |
| SU (1) | SU372834A3 (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4393632A (en) * | 1981-01-26 | 1983-07-19 | C. Levesque Co. Inc. | Building system |
| FR2520408A1 (fr) * | 1982-01-22 | 1983-07-29 | Smac Acieroid | Element d'isolation exterieure et veture utilisant de tels elements |
| AT398105B (de) * | 1990-07-12 | 1994-09-26 | Reinisch Erwin | Verkleidung von bauwerken od.dgl. und verfahren zu ihrer herstellung |
| US5475957A (en) * | 1993-11-22 | 1995-12-19 | Toyo Shutter Co., Ltd. | Building |
| DE4403014A1 (de) * | 1994-02-01 | 1995-08-03 | Steuler Industriewerke Gmbh | Vorrichtung und Verfahren zur Auskleidung eines statischen Trägers mit Kunststoffplatten |
| DE19811792A1 (de) * | 1998-03-18 | 1999-09-23 | Alstom Lhb Gmbh | Verfahren zur lösbaren Befestigung von Verkleidungsteilen mit Toleranzausgleich an Trägern mit Aufnahmerastern sowie ein nach diesem Verfahren hergestelltes Erzeugnis |
| US20050262798A1 (en) * | 2004-05-17 | 2005-12-01 | Todd Pringle | Window and door trim system |
| WO2012167270A1 (en) | 2011-06-03 | 2012-12-06 | Hercuwall Inc | Stronger wall system |
| US9458637B2 (en) * | 2012-09-25 | 2016-10-04 | Romeo Ilarian Ciuperca | Composite insulated plywood, insulated plywood concrete form and method of curing concrete using same |
| WO2014186299A1 (en) | 2013-05-13 | 2014-11-20 | Ciuperca Romeo Llarian | Insulated concrete battery mold, insulated passive concrete curing system, accelerated concrete curing apparatus and method of using same |
| US10065339B2 (en) | 2013-05-13 | 2018-09-04 | Romeo Ilarian Ciuperca | Removable composite insulated concrete form, insulated precast concrete table and method of accelerating concrete curing using same |
| WO2015035409A2 (en) | 2013-09-09 | 2015-03-12 | Ciuperca Romeo Llarian | Insulated concrete slip form and method of accelerating concrete curing using same |
| CA2956649A1 (en) | 2016-01-31 | 2017-07-31 | Romeo Ilarian Ciuperca | Self-annealing concrete forms and method of making and using same |
| WO2023146418A1 (en) * | 2022-01-27 | 2023-08-03 | Dbsorb Limited | Panel mount(s), panel system and methods of prefabricating and mounting a panel |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2298743A (en) * | 1942-10-13 | Means for removably positioning | ||
| US1972412A (en) * | 1932-03-28 | 1934-09-04 | Van Dresser Specialty Corp | Trimming |
| US2018201A (en) * | 1932-12-20 | 1935-10-22 | Mosaic Tile Company | Wall or base tile |
| US1973795A (en) * | 1933-02-04 | 1934-09-18 | Jr Munroe W Copper | Building construction |
| US2023452A (en) * | 1933-02-06 | 1935-12-10 | American Brass Co | Wall construction |
| US2005994A (en) * | 1933-05-27 | 1935-06-25 | Russell L Hohl | Building construction |
| US2056359A (en) * | 1935-06-29 | 1936-10-06 | Albert H Marty | Wall construction |
| US2135118A (en) * | 1936-04-18 | 1938-11-01 | Andrew H Stewart | Tile-mounting structure |
| US2101181A (en) * | 1936-10-02 | 1937-12-07 | Libbey Owens Ford Glass Co | Building block |
| US2227452A (en) * | 1937-03-30 | 1941-01-07 | Philip M Jullien | Construction unit |
| US2318820A (en) * | 1938-06-04 | 1943-05-11 | Johns Manville | Building construction |
| US2357525A (en) * | 1941-09-17 | 1944-09-05 | Libbey Owens Ford Glass Co | Wall construction |
| DE1870958U (de) * | 1961-02-02 | 1963-04-25 | Rostan Bauunternehmung Und Bet | Fuer eine bauwerkswand bestimmte wandplatte. |
-
1966
- 1966-11-03 DE DEK60626A patent/DE1296325B/de active Pending
-
1967
- 1967-10-30 AT AT975567A patent/AT285126B/de not_active IP Right Cessation
- 1967-10-30 BE BE705874D patent/BE705874A/xx unknown
- 1967-10-31 NL NL6714769A patent/NL6714769A/xx unknown
- 1967-11-01 FI FI2943/67A patent/FI43232B/fi active
- 1967-11-02 DK DK545567AA patent/DK124622B/da unknown
- 1967-11-02 SE SE15060/67A patent/SE321066B/xx unknown
- 1967-11-02 NO NO170373A patent/NO120701B/no unknown
- 1967-11-03 CH CH1541267A patent/CH457796A/de unknown
- 1967-11-03 SU SU1194767A patent/SU372834A3/ru active
- 1967-11-03 US US680503A patent/US3435573A/en not_active Expired - Lifetime
- 1967-11-03 GB GB50046/67A patent/GB1209773A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT285126B (de) | 1970-10-12 |
| SU372834A3 (da) | 1973-03-01 |
| DE1296325B (de) | 1969-05-29 |
| NL6714769A (da) | 1968-05-06 |
| DK124622B (da) | 1972-11-06 |
| BE705874A (da) | 1968-03-01 |
| US3435573A (en) | 1969-04-01 |
| SE321066B (da) | 1970-02-23 |
| GB1209773A (en) | 1970-10-21 |
| FI43232B (da) | 1970-11-02 |
| CH457796A (de) | 1968-06-15 |
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