NO117986B - - Google Patents
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- Publication number
- NO117986B NO117986B NO65160376A NO16037665A NO117986B NO 117986 B NO117986 B NO 117986B NO 65160376 A NO65160376 A NO 65160376A NO 16037665 A NO16037665 A NO 16037665A NO 117986 B NO117986 B NO 117986B
- Authority
- NO
- Norway
- Prior art keywords
- dried
- freeze
- drying
- dextran
- vaccine
- Prior art date
Links
- 239000000463 material Substances 0.000 claims description 27
- 229920002307 Dextran Polymers 0.000 claims description 26
- 229960005486 vaccine Drugs 0.000 claims description 26
- 238000004108 freeze drying Methods 0.000 claims description 24
- 238000000034 method Methods 0.000 claims description 23
- 239000000080 wetting agent Substances 0.000 claims description 11
- 241000700605 Viruses Species 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 claims description 7
- 102000004190 Enzymes Human genes 0.000 claims description 6
- 108090000790 Enzymes Proteins 0.000 claims description 6
- 241000894006 Bacteria Species 0.000 claims description 5
- 239000000126 substance Substances 0.000 claims description 4
- 239000007864 aqueous solution Substances 0.000 claims description 2
- 230000001105 regulatory effect Effects 0.000 claims 1
- 239000000243 solution Substances 0.000 description 20
- 238000001035 drying Methods 0.000 description 17
- 239000000047 product Substances 0.000 description 17
- 239000000725 suspension Substances 0.000 description 16
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 9
- 239000008103 glucose Substances 0.000 description 9
- 239000002609 medium Substances 0.000 description 8
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 6
- 210000004027 cell Anatomy 0.000 description 5
- 230000035899 viability Effects 0.000 description 5
- 238000002255 vaccination Methods 0.000 description 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- 244000052616 bacterial pathogen Species 0.000 description 3
- 238000007710 freezing Methods 0.000 description 3
- 230000008014 freezing Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 210000002966 serum Anatomy 0.000 description 3
- 241000588832 Bordetella pertussis Species 0.000 description 2
- 102000016911 Deoxyribonucleases Human genes 0.000 description 2
- 108010053770 Deoxyribonucleases Proteins 0.000 description 2
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 239000002274 desiccant Substances 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 235000013601 eggs Nutrition 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 235000021588 free fatty acids Nutrition 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 239000008101 lactose Substances 0.000 description 2
- 239000002504 physiological saline solution Substances 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- DLYUQMMRRRQYAE-UHFFFAOYSA-N tetraphosphorus decaoxide Chemical compound O1P(O2)(=O)OP3(=O)OP1(=O)OP2(=O)O3 DLYUQMMRRRQYAE-UHFFFAOYSA-N 0.000 description 2
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 2
- 235000006491 Acacia senegal Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 244000165918 Eucalyptus papuana Species 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- 241000192132 Leuconostoc Species 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 102000006382 Ribonucleases Human genes 0.000 description 1
- 108010083644 Ribonucleases Proteins 0.000 description 1
- 241000187747 Streptomyces Species 0.000 description 1
- 241000187759 Streptomyces albus Species 0.000 description 1
- 241000187392 Streptomyces griseus Species 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 230000002052 anaphylactic effect Effects 0.000 description 1
- 235000021120 animal protein Nutrition 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- 229960001212 bacterial vaccine Drugs 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003245 coal Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 239000006619 dextran medium Substances 0.000 description 1
- 238000010981 drying operation Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000010985 leather Substances 0.000 description 1
- 231100000518 lethal Toxicity 0.000 description 1
- 230000001665 lethal effect Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 230000001333 moisturizer Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229940066827 pertussis vaccine Drugs 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 239000003058 plasma substitute Substances 0.000 description 1
- 235000019833 protease Nutrition 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- VMOXILJFUFEZJL-UHFFFAOYSA-M sodium;ethylmercury;2-sulfanylbenzoate Chemical compound [Na+].CC[Hg].[O-]C(=O)C1=CC=CC=C1S VMOXILJFUFEZJL-UHFFFAOYSA-M 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000008174 sterile solution Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
Classifications
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03D—DEMODULATION OR TRANSFERENCE OF MODULATION FROM ONE CARRIER TO ANOTHER
- H03D1/00—Demodulation of amplitude-modulated oscillations
- H03D1/22—Homodyne or synchrodyne circuits
- H03D1/2281—Homodyne or synchrodyne circuits using a phase locked loop
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03C—MODULATION
- H03C3/00—Angle modulation
- H03C3/02—Details
- H03C3/06—Means for changing frequency deviation
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03D—DEMODULATION OR TRANSFERENCE OF MODULATION FROM ONE CARRIER TO ANOTHER
- H03D1/00—Demodulation of amplitude-modulated oscillations
- H03D1/22—Homodyne or synchrodyne circuits
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03D—DEMODULATION OR TRANSFERENCE OF MODULATION FROM ONE CARRIER TO ANOTHER
- H03D3/00—Demodulation of angle-, frequency- or phase- modulated oscillations
- H03D3/001—Details of arrangements applicable to more than one type of frequency demodulator
- H03D3/003—Arrangements for reducing frequency deviation, e.g. by negative frequency feedback
- H03D3/004—Arrangements for reducing frequency deviation, e.g. by negative frequency feedback wherein the demodulated signal is used for controlling an oscillator, e.g. the local oscillator
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03D—DEMODULATION OR TRANSFERENCE OF MODULATION FROM ONE CARRIER TO ANOTHER
- H03D5/00—Circuits for demodulating amplitude-modulated or angle-modulated oscillations at will
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04B—TRANSMISSION
- H04B15/00—Suppression or limitation of noise or interference
- H04B15/02—Reducing interference from electric apparatus by means located at or near the interfering apparatus
- H04B15/04—Reducing interference from electric apparatus by means located at or near the interfering apparatus the interference being caused by substantially sinusoidal oscillations, e.g. in a receiver or in a tape-recorder
- H04B15/06—Reducing interference from electric apparatus by means located at or near the interfering apparatus the interference being caused by substantially sinusoidal oscillations, e.g. in a receiver or in a tape-recorder by local oscillators of receivers
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N5/00—Details of television systems
- H04N5/44—Receiver circuitry for the reception of television signals according to analogue transmission standards
- H04N5/50—Tuning indicators; Automatic tuning control
Landscapes
- Engineering & Computer Science (AREA)
- Power Engineering (AREA)
- Signal Processing (AREA)
- Computer Networks & Wireless Communication (AREA)
- Multimedia (AREA)
- Superheterodyne Receivers (AREA)
- Amplifiers (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Amplitude Modulation (AREA)
- Television Receiver Circuits (AREA)
- Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
- Television Systems (AREA)
- Digital Transmission Methods That Use Modulated Carrier Waves (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEST22924A DE1221272B (de) | 1964-11-10 | 1964-11-10 | Vierstufiger transistorisierter Videoverstaerker |
| DEST22923A DE1218020B (de) | 1964-11-10 | 1964-11-10 | Verfahren zur Demodulation einer hochfrequenten elektrischen Schwingung |
| DEST22927A DE1254200B (de) | 1964-11-10 | 1964-11-11 | Synchrodynempfaenger fuer hochfrequente elektrische Schwingungen |
| DEST023659 | 1965-04-09 | ||
| DE1965ST024726 DE1283928C2 (de) | 1964-11-10 | 1965-12-03 | Synchrodynempfaenger fuer hochfrequente elektrische schwingungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO117986B true NO117986B (fi) | 1969-10-20 |
Family
ID=27512246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO65160376A NO117986B (fi) | 1964-11-10 | 1965-11-08 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US3454710A (fi) |
| BE (3) | BE672125A (fi) |
| CH (3) | CH454969A (fi) |
| FI (1) | FI46447C (fi) |
| GB (3) | GB1131245A (fi) |
| NL (3) | NL150288B (fi) |
| NO (1) | NO117986B (fi) |
| SE (3) | SE321698B (fi) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3946148A (en) * | 1974-10-03 | 1976-03-23 | Zenith Radio Corporation | Television receiver operable in exact or extended range tuning modes |
| US3939341A (en) * | 1975-04-02 | 1976-02-17 | Hughes Aircraft Company | Phase-locked optical homodyne receiver |
| US4346477A (en) * | 1977-08-01 | 1982-08-24 | E-Systems, Inc. | Phase locked sampling radio receiver |
| US4715001A (en) * | 1984-08-23 | 1987-12-22 | Motorola, Inc. | Extremely accurate automatic frequency control circuit and method therefor |
| NL8403648A (nl) * | 1984-11-30 | 1986-06-16 | Philips Nv | Fasegesleutelde lus in het bijzonder voor toepassing in een direktmengende am-synchroonontvanger. |
| JPH01132253A (ja) * | 1987-11-18 | 1989-05-24 | Hitachi Ltd | 位相制御装置 |
| US5140703A (en) * | 1988-10-14 | 1992-08-18 | Payne Christopher P | Modulation distortion analyzer |
| US5444865A (en) * | 1991-04-01 | 1995-08-22 | Motorola, Inc. | Generating transmit injection from receiver first and second injections |
| KR19990008178A (ko) * | 1996-04-04 | 1999-01-25 | 이데이노브유끼 | 텔레비전 수신장치 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2231704A (en) * | 1939-03-04 | 1941-02-11 | Hazeltine Corp | Homodyne receiver |
| GB840485A (en) * | 1958-02-14 | 1960-07-06 | Gen Electric Co Ltd | Improvements in or relating to arrangements for demodulating electric carrier oscillations that are modulated by television signals |
| US3144512A (en) * | 1961-05-03 | 1964-08-11 | Int Standard Electric Corp | Televsion signal receiver terminal |
-
1965
- 1965-11-08 SE SE14333/65A patent/SE321698B/xx unknown
- 1965-11-08 NO NO65160376A patent/NO117986B/no unknown
- 1965-11-08 US US506647A patent/US3454710A/en not_active Expired - Lifetime
- 1965-11-10 FI FI652693A patent/FI46447C/fi active
- 1965-11-10 GB GB47664/65A patent/GB1131245A/en not_active Expired
- 1965-11-10 NL NL656514619A patent/NL150288B/xx unknown
- 1965-11-10 BE BE672125D patent/BE672125A/nl unknown
- 1965-11-10 CH CH1549865A patent/CH454969A/de unknown
-
1966
- 1966-04-05 NL NL666604586A patent/NL151600B/xx unknown
- 1966-04-06 CH CH505066A patent/CH478488A/de unknown
- 1966-04-07 GB GB15564/66A patent/GB1136451A/en not_active Expired
- 1966-04-07 SE SE4803/66A patent/SE344664B/xx unknown
- 1966-04-07 BE BE679172D patent/BE679172A/xx unknown
- 1966-11-08 US US592774A patent/US3519740A/en not_active Expired - Lifetime
- 1966-11-29 CH CH1699966A patent/CH486803A/de unknown
- 1966-12-01 NL NL666616908A patent/NL153742B/xx unknown
- 1966-12-01 SE SE16440/66A patent/SE345571B/xx unknown
- 1966-12-02 GB GB54107/66A patent/GB1146865A/en not_active Expired
- 1966-12-05 BE BE690662D patent/BE690662A/nl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE345571B (fi) | 1972-05-29 |
| BE690662A (fi) | 1967-06-05 |
| NL151600B (nl) | 1976-11-15 |
| NL6616908A (fi) | 1967-06-05 |
| SE321698B (fi) | 1970-03-16 |
| BE672125A (fi) | 1966-05-10 |
| NL150288B (nl) | 1976-07-15 |
| NL6604586A (fi) | 1966-10-10 |
| BE679172A (fi) | 1966-10-07 |
| FI46447B (fi) | 1972-11-30 |
| US3454710A (en) | 1969-07-08 |
| CH478488A (de) | 1969-09-15 |
| CH486803A (de) | 1970-02-28 |
| NL6514619A (fi) | 1966-05-11 |
| CH454969A (de) | 1968-04-30 |
| GB1131245A (en) | 1968-10-23 |
| FI46447C (fi) | 1973-03-12 |
| SE344664B (fi) | 1972-04-24 |
| GB1136451A (en) | 1968-12-11 |
| NL153742B (nl) | 1977-06-15 |
| GB1146865A (en) | 1969-03-26 |
| US3519740A (en) | 1970-07-07 |
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